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12560

Total database: 17430
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9109 (72.5%)
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12560 (100.0%)

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Halaman 64 / 252
Blinatumomab Approved DB09052
biotech | CAS: 853426-35-4

Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an ant…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +17
Target Protein:
B-lymphocyte antigen CD19T-cell surface glycoprotein CD3 delta chain
Waktu ParuhBlinatumomab has a …
Vol. DistribusiBlinatumomab has a …
KlirensBlinatumomab has an…
Genetik -
Blisibimod DB12330
biotech | CAS: 1236126-45-6

Blisibimod has been used in trials studying the treatment of IgA Nephropathy, Microscopic Polyangiitis, Systemic Lupus Erythematosus, and Granulomatosis With Polyangiitis.

Kategori:
Amino Acids, Peptides, and ProteinsB-Cell Activating FactorImmunologic Factors +2
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Blosozumab DB12560
biotech | CAS: 1132758-87-2

Blosozumab has been used in trials studying the basic science and treatment of Osteoporosis and Osteoporosis, Postmenopausal.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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BLU-9931 DB17985
small molecule | CAS: 1538604-68-0

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAcrylatesAmides +1
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BLX-883 DB05904
small molecule

BLX-883 is a form of alfa interferon developed by Biolex for the treatment of hepatitis viral C. Alfa interferon is used in the treatment of hepatitis C, hepatitis B, and multiple cancers and its worldwide sales currently exceed $3 billion.

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BLXA4 DB12133
small molecule | CAS: 864516-86-9

BLXA4 has been used in trials studying the treatment of Gingival Inflammation.

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BLZ-945 DB16838
small molecule | CAS: 953769-46-5

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingPyridinesReceptor, Macrophage Colony-Stimulating Factor, antagonists & inhibitors +1
Target Protein:
Granulocyte colony-stimulating factor receptorMacrophage colony-stimulating factor 1 receptor
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BM-3103 DB18056
small molecule

Deskripsi belum tersedia.

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BMN-045 DB17004
biotech

Deskripsi belum tersedia.

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BMN-046 DB17005
biotech

Deskripsi belum tersedia.

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BMN-052 DB17006
biotech

Deskripsi belum tersedia.

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BMN-053 DB17008
biotech

Deskripsi belum tersedia.

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BMN-055 DB17009
biotech

Deskripsi belum tersedia.

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BMN-351 DB18186
biotech

BMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to exon 51 of dystrophin pre-mRNA. It is under investigation for the treatment of Duchenne Muscular Dystrophy (DMD).

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BMS-181156 DB02466
small molecule | CAS: 110368-35-9

Deskripsi belum tersedia.

Target Protein:
Retinoic acid receptor gamma
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BMS-184476 DB12633
small molecule | CAS: 160237-25-2

BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
CyclodecanesCycloparaffinsDiterpenes +1
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BMS-214662 DB12234
small molecule | CAS: 195987-41-8

BMS-214662 has been used in trials studying the treatment of Childhood Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Relapsing Chronic Myelogenous Leukemia, and Adult Acute Promyelocytic Leukemia (M3)…

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-Ring
Target Protein:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit beta
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BMS-275183 DB12144
small molecule | CAS: 355113-98-3

BMS-275183 has been used in trials studying the treatment of Tumors and Non-small Cell Lung Cancer.

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BMS-488043 DB05532
small molecule | CAS: 452296-83-2

BMS-488043 has been investigated as an anti-HIV agent.

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +6
Target Protein:
Free fatty acid receptor 4
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BMS-564929 DB07286
small molecule | CAS: 627530-84-1

BMS-564929 is an investigational therapeutic agent built to be a selective androgen receptor modulator (SARM). So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause.

Target Protein:
Androgen receptor
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BMS-582949 DB12696
small molecule | CAS: 623152-17-0

BMS-582949 has been investigated for the treatment of Psoriasis.

Kategori:
Mitogen-Activated Protein Kinase 14, antagonists & inhibitors
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BMS-599626 DB12318
small molecule | CAS: 714971-09-2

BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.

Kategori:
Acids, AcyclicErbB Receptors, antagonists & inhibitors
Target Protein:
Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2
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BMS-690514 DB11665
small molecule | CAS: 859853-30-8

BMS-690514 has been investigated for the treatment of Breast Cancer.

Kategori:
Carbon Radioisotopes
Target Protein:
Vascular endothelial growth factor receptor 2Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2 +1
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BMS-741672 DB19004
small molecule | CAS: 1386991-77-0

BMS-741672 is under investigation in clinical trial NCT00699790 (Proof of Confidence Study of CCR2 Antagonist (BMS-741672) in Insulin Resistance).

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BMS-754807 DB15399
small molecule | CAS: 1001350-96-4

BMS-754807 is under investigation in clinical trial NCT00908024 (Combination Study of BMS-754807 and Erbitux® in Subjects With Advanced or Metastatic Solid Tumors).

Target Protein:
RAC-alpha serine/threonine-protein kinaseInsulin-like growth factor 1 receptorInsulin receptor
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BMS-770767 DB18902
small molecule | CAS: 1875067-34-7

BMS-770767 is under investigation in clinical trial NCT01058083 (Safety Study of BMS-770767 in Subjects With Hypercholesterolemia).

Kategori:
Carbon Radioisotopes
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BMS-777607 DB12064
small molecule | CAS: 1025720-94-8

BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.

Kategori:
AminesPyridines
Target Protein:
Hepatocyte growth factor receptor
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BMS-791826 DB15023
small molecule | CAS: 1008116-73-1

BMS-791826 is under investigation in clinical trial NCT03198013 (A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males).

Kategori:
Heterocyclic Compounds, Fused-RingSulfur CompoundsThiazoles
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BMS-813160 DB16240
small molecule | CAS: 1286279-29-5

BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).

Kategori:
Cardiovascular Agents
Target Protein:
C-C chemokine receptor type 2C-C chemokine receptor type 5
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BMS-817399 DB14941
small molecule | CAS: 1202400-18-7

BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).

Kategori:
AmidesAmino AcidsAmino Acids, Branched-Chain +1
Target Protein:
C-C chemokine receptor type 1
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BMS-833923 DB16844
small molecule | CAS: 1059734-66-5

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
Target Protein:
Protein smoothened
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BMS-863233 DB12357
small molecule | CAS: 1169558-38-6

BMS-863233 has been investigated for the treatment of Refractory Hematologic Cancer.

Target Protein:
Cell division cycle 7-related protein kinase
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BMS-903452 DB11773
small molecule | CAS: 1339944-47-6

BMS-903452 has been used in trials studying the treatment of Diabetes.

Kategori:
PyridinesSulfur Compounds
Target Protein:
Glucose-dependent insulinotropic receptor
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BMS-908662 DB12854
small molecule | CAS: 870603-16-0

BMS-908662 has been used in trials studying the treatment of Melanoma and Colorectal Cancer.

Target Protein:
Serine/threonine-protein kinase B-raf
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BMS-911543 DB12591
small molecule | CAS: 1271022-90-2

BMS-911543 has been used in trials studying the treatment of Cancer.

Kategori:
Heterocyclic Compounds, Fused-RingJanus Kinase 2, antagonists & inhibitorsJanus Kinases, antagonists & inhibitors
Target Protein:
Tyrosine-protein kinase JAK2
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BMS-919373 DB15047
small molecule | CAS: 1272353-82-8

BMS-919373 is under investigation in clinical trial NCT02153437 (Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers).

Target Protein:
Potassium voltage-gated channel subfamily A member 5
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BMS-929075 DB14950
small molecule | CAS: 1217338-97-0

BMS-929075 is under investigation in clinical trial NCT01525212 (Multiple Ascending Dose Study of BMS-929075 in Hepatitis C Virus (HCV) Infected Patients).

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BMS-955176 DB15193
small molecule | CAS: 1392312-45-6

BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults).

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +2
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BMS-986012 DB14831
biotech | CAS: 1894272-37-7

BMS-986012 is a human antifucosyl-GM1 antibody. It is under investigation in clinical trial NCT02815592 (Trial of BMS-986012 in Combination With Platinum and Etoposide).

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BMS-986020 DB14948
small molecule | CAS: 1257213-50-5

BMS-986020 is under investigation in clinical trial NCT02017730 (To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy Volunteers).

Target Protein:
Lysophosphatidic acid receptor 1
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BMS-986094 DB11966
small molecule | CAS: 1234490-83-5

INX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis C Virus.

Kategori:
Guanine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4
Target Protein:
Genome polyprotein
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BMS-986104 DB15214
small molecule | CAS: 1622180-31-7

BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986104 in Healthy Male Subjects).

Target Protein:
Sphingosine 1-phosphate receptor 1
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BMS-986115 DB13126
small molecule | CAS: 1584647-27-7

BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer.

Kategori:
BenzazepinesEnzyme InhibitorsGamma Secretase Inhibitors and Modulators +1
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BMS-986141 DB14942
small molecule | CAS: 1478711-48-6

BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Target Protein:
PRKC apoptosis WT1 regulator protein
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BMS-986142 DB15291
small molecule | CAS: 1643368-58-4

BMS-986142 is under investigation in clinical trial NCT02880670 (Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects).

Target Protein:
Tyrosine-protein kinase BTK
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BMS-986158 DB15435
small molecule | CAS: 1800340-40-2

BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With Select Advanced Cancers).

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BMS-986251 DB19007
small molecule | CAS: 2041841-30-7

BMS-986251 is under investigation in clinical trial NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis).

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BMS-986278 DB18011
small molecule | CAS: 2170126-74-4

Deskripsi belum tersedia.

Target Protein:
Lysophosphatidic acid receptor 1
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small molecule | CAS: 1379866-50-8

Deskripsi belum tersedia.

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BN-201 DB18295
small molecule | CAS: 1361200-34-1

Deskripsi belum tersedia.

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