Hasil Filter

16004

Total database: 17430
Struktur (SMILES)
12010 (75.0%)
Target
9041 (56.5%)
Genomik
112 (0.7%)
Referensi
16004 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (16004)

Halaman 64 / 321
small molecule | CAS: 14215-68-0

The N-acetyl derivative of galactosamine. [PubChem]

Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Chloramphenicol 3-O phosphotransferase
Waktu Paruh-
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Genetik -
small molecule | CAS: 604-59-1

Deskripsi belum tersedia.

Kategori:
BenzopyransChromonesFlavonoids +2
Target Protein:
DNA-dependent protein kinase catalytic subunitAromataseCytochrome P450 1A2
Waktu Paruh-
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Genetik -
alpha-Pinene DB15573
small molecule | CAS: 80-56-8

Deskripsi belum tersedia.

Kategori:
Bridged-Ring CompoundsMonoterpenesTerpenes
Waktu Paruh-
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Genetik -
small molecule | CAS: 13415-58-2

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Waktu Paruh-
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Genetik -
alpha-Tocopherol acetate Approved DB14003
small molecule | CAS: 7695-91-2

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is conside…

Kategori:
AntioxidantsBenzopyransBiological Factors +16
Target Protein:
Free radicals
Waktu ParuhThe apparent half-l…
Vol. DistribusiWhen three particul…
KlirensWhen three specific…
Genetik -
alpha-Tocopherol succinate Approved DB14001
small molecule | CAS: 4345-03-3

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is conside…

Kategori:
AntioxidantsBenzopyransBiological Factors +12
Target Protein:
SEC14-like protein 3SEC14-like protein 2Nuclear receptor subfamily 1 group I member 2 +5
Waktu Paruh_In addition to any…
Vol. Distribusi_In addition to any…
Klirens_In addition to any…
Genetik -
small molecule | CAS: 17199-58-5

A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]

Kategori:
AnalgesicsCentral Nervous System AgentsCentral Nervous System Depressants +6
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Alphameprodine DB01499
small molecule | CAS: 468-51-9

Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred…

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Alphamethadol DB01498
small molecule | CAS: 17199-54-1

Deskripsi belum tersedia.

Waktu Paruh-
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Alphaprodine DB13160
small molecule | CAS: 77-20-3

Deskripsi belum tersedia.

Kategori:
AnalgesicsCentral Nervous System AgentsCentral Nervous System Depressants +6
Waktu Paruh-
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Genetik -
biotech

Deskripsi belum tersedia.

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Alprazolam Approved DB00404
small molecule | CAS: 28981-97-7

Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiaz…

Kategori:
AminesAnti-Anxiety AgentsBenzazepines +25
Target Protein:
GABA(A) ReceptorTranslocator proteinGABA(A) Receptor Benzodiazepine Binding Site
Waktu ParuhAlprazolam has a me…
Vol. DistribusiAlprazolam has a vo…
KlirensA 0.8 mg oral dose …
Genetik -
Alprenolol DB00866
small molecule | CAS: 13655-52-2

One of the adrenergic beta-antagonists used as an antihypertensive, anti-anginal, and anti-arrhythmic agent. Alprenolol is no longer marketed by AstraZeneca, but may still be available in generic varieties.

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-Antagonists +24
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptor5-hydroxytryptamine receptor 1A +1
Waktu Paruh2-3 hours
Vol. Distribusi-
Klirens-
Genetik -
Alprostadil Approved DB00770
small molecule | CAS: 745-65-3

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppositor…

Kategori:
AutacoidsBiological FactorsCardiac Therapy +27
Target Protein:
Thromboxane A2 receptorProstaglandin E2 receptor EP1 subtypeProstaglandin E2 receptor EP2 subtype +3
Waktu ParuhIn healthy adults a…
Vol. DistribusiThe volume of distr…
KlirensIn patients with er…
Genetik -
Alrestatin DB02020
small molecule | CAS: 51411-04-2

Deskripsi belum tersedia.

Kategori:
Autonomic AgentsEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +2
Target Protein:
Aldo-keto reductase family 1 member B1
Waktu Paruh-
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Genetik -
Alrizomadlin DB17549
small molecule | CAS: 1818393-16-6

Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]

Target Protein:
E3 ubiquitin-protein ligase Mdm2Cellular tumor antigen p53
Waktu Paruh-
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ALS-08 DB05705
small molecule

ALS-08 is a proprietary creatine-derivative that is being developed as a potential therapeutic for amyotrophic lateral sclerosis (ALS). It is being developed by Avicena Group, Inc.

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Alsactide DB13298
small molecule | CAS: 34765-96-3

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsDiagnostic AgentsHormones +12
Waktu Paruh-
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ALT-2074 DB05631
small molecule | CAS: 173026-17-0

An organoselenium drug previously studied by Oxis International in Phase-II clinical trials for ulcerative colitis patients. Some indications of efficacy were demonstrated. BXT-51072 has enthusiastic endorsement for treatment in cardiovascular indications, pr…

Kategori:
Selenium Compounds
Target Protein:
Nitric oxide synthase, inducible
Waktu Paruh2.08 (+/-0.17) hour…
Vol. Distribusi-
Klirens24.15 (+/-2.38) (ml…
Genetik -
ALT-801 DB15386
biotech | CAS: 1188450-53-4

ALT-801 is under investigation in clinical trial NCT01478074 (ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +8
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ALT-P1 DB18485
biotech

ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.

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ALT-P7 DB17220
biotech

Deskripsi belum tersedia.

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Alteplase Approved DB00009
biotech | CAS: 105857-23-6

Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of…

Kategori:
Agents causing angioedemaAmino Acids, Peptides, and ProteinsAnticoagulants +19
Target Protein:
PlasminogenFibrinogen alpha chainFibrinogen gamma chain +1
Waktu ParuhAlteplase has an in…
Vol. DistribusiThe initial volume …
KlirensAlteplase has a pla…
Genetik -
Altiratinib DB17191
small molecule | CAS: 1345847-93-9

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +1
Target Protein:
High affinity nerve growth factor receptorNT-3 growth factor receptorVascular endothelial growth factor receptor 2 +2
Waktu Paruh-
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Genetik -
Altrenogest DB11372
small molecule | CAS: 850-52-2

Altrenogest, also known as allyltrenbolone, is a steroidal progestin that is widely used in veterinary medicine to suppress estrus in animals.

Kategori:
Adrenal Cortex HormonesEstranesEstrenes +6
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Altretamine Approved DB00488
small molecule | CAS: 645-05-6

An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.

Kategori:
Alkylating ActivityAlkylating DrugsAntineoplastic Agents +8
Target Protein:
DNA
Waktu Paruh4.7-10.2 hours
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Altropane DB04947
small molecule | CAS: 180468-34-2

Boston Life Sciences (BLS) is developing Altropane as a potential radio-imaging agent to be used with single photon emission tomography (SPECT), for the early diagnosis of Parkinson's disease (PD) and attention deficit hyperactivity disorder (ADHD).

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +2
Target Protein:
Sodium-dependent dopamine transporter
Waktu Paruh-
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Altropane I-123 DB15144
small molecule | CAS: 208517-65-1

Altropane I-123 is under investigation in clinical trial NCT01950468 (A Cross-Over, Multi-Center Trial to Evaluate the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes).

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ALTU-135 DB05330
biotech

ALTU-135, the Company's orally administered enzyme replacement therapy for patients with pancreatic insufficiency, is manufactured by blending three drug substance enzymes: lipase, protease and amylase. This consistent and pure enzyme combination is designed …

Kategori:
Carboxylic Ester HydrolasesEnzymesEnzymes and Coenzymes +3
Waktu Paruh-
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Aluminium Approved DB01370
small molecule | CAS: 7429-90-5

A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.

Kategori:
Aluminium CompoundsAluminum and magnesium containing antacidsAntacids +6
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1Kallikrein-1Amyloid-beta precursor protein +1
Waktu Paruh-
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small molecule | CAS: 19022-77-6

Aluminium acetoacetate is an aluminum containing antacid.

Kategori:
Alimentary Tract and MetabolismAluminium CompoundsAluminum and magnesium containing antacids +5
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small molecule | CAS: 15930-12-8

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsOtologicalsSensory Organs
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Genetik -
small molecule | CAS: 24818-79-9

Deskripsi belum tersedia.

Kategori:
Agents Causing Muscle ToxicityFibric AcidsLipid Modifying Agents +2
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small molecule | CAS: 41354-48-7

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAlkaliesAluminium Compounds +12
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small molecule | CAS: 7047-84-9

Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of …

Kategori:
Fatty AcidsLipids
Target Protein:
Troponin C, slow skeletal and cardiac musclesNon-selective voltage-gated ion channel VDAC1Voltage-dependent anion-selective channel protein 2 +1
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small molecule | CAS: 1976-28-9

Deskripsi belum tersedia.

Kategori:
Lipid Modifying AgentsLipid Modifying Agents, PlainNicotinic Acid and Derivatives
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Aluminium phosphate Approved DB14517
small molecule | CAS: 7784-30-7

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAdjuvants, Immunologic +16
Target Protein:
SerotransferrinSodium/potassium-transporting ATPase subunit alpha-1Kallikrein-1 +1
Waktu Paruh-
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Genetik -
small molecule | CAS: 637-12-7

Deskripsi belum tersedia.

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Aluminum acetate Approved DB14518
small molecule | CAS: 139-12-8

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
Target Protein:
SerotransferrinSodium/potassium-transporting ATPase subunit alpha-1Kallikrein-1 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Aluminum cation DB14519
small molecule | CAS: 22537-23-1

Deskripsi belum tersedia.

Kategori:
Polyvalent cation containing laxatives, antacids, oral supplements
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Aluminum chloride Approved DB11081
small molecule | CAS: 7446-70-0

Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. It is used in various chemical applications as a Lewis base, with anhydrous a…

Kategori:
Aluminium CompoundsAnti-Acne PreparationsAnti-Acne Preparations for Topical Use +10
Target Protein:
Glutamate dehydrogenase 1, mitochondrial
Waktu ParuhFollowing oral admi…
Vol. DistribusiFollowing oral admi…
KlirensFollowing oral admi…
Genetik -
Aluminum chlorohydrate Approved DB11573
small molecule | CAS: 12359-72-7

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydr…

Kategori:
AlkaliesAluminium CompoundsAnions +12
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
small molecule | CAS: 53026-85-0

Aluminum chlorohydrex propylene glycol is a complex consisting of Aluminum Chorohydrate and propylene glycol (PG). It is an antiperspirant active ingredient found in antiperspirant drug products for over-the-counter human use.

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Aluminum hydroxide Approved DB06723
small molecule | CAS: 21645-51-2

Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandi…

Kategori:
Adjuvants, ImmunologicAlimentary Tract and MetabolismAlkalies +17
Waktu Paruh-
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Aluminum oxide Approved DB11342
small molecule | CAS: 1344-28-1

Aluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in food contact substances by the FDA.

Kategori:
Aluminium CompoundsAluminum OxidesAnti-Acne Preparations +6
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Aluminum subacetate Approved DB15679
small molecule | CAS: 142-03-0

Deskripsi belum tersedia.

Kategori:
Astringents
Waktu Paruh-
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Aluminum sulfate Approved DB11239
small molecule | CAS: 10043-01-3

Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table [L2148]. It is a chemical agent used in water purification, the pH regulation of garden soil, and other…

Kategori:
Adjuvants, ImmunologicAluminium CompoundsImmunologic Factors +6
Waktu ParuhNumerous studies ha…
Vol. DistribusiAluminium which is …
Klirens-
Genetik -
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