Hasil Filter

17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (17430)

Halaman 63 / 349
biotech

Beef liver allergenic extract is used in allergenic testing.

Kategori:
Non-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allicin DB11780
small molecule | CAS: 539-86-6

Allicin has been used in trials studying the treatment of Follicular Lymphoma.

Kategori:
AcidsAcids, NoncarboxylicAnions +15
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 947331-05-7

Allisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).

Kategori:
Agents Acting on the Renin-Angiotensin SystemAngiotensin II receptor antagonistsAngiotensin II Type 1 Receptor Blockers +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allitinib DB18840
small molecule | CAS: 897383-62-9

Allitinib is under investigation in clinical trial NCT04671303 (To Evaluate the Efficacy and Safety of Anlotinib Combined With Allitinib in Lung Cancer).

Kategori:
Acids, AcyclicAcrylatesAmides +2
Target Protein:
Epidermal growth factor receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ALLO-605 DB18641
biotech

ALLO-605 is an allogeneic turbo chimeric antigen receptor (Turbocar) T Cell therapy targeting B Cell maturation antigen (BCMA).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ALLO-715 DB18640
biotech

ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen (BCMA).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allobarbital DB13577
small molecule | CAS: 52-43-7

Deskripsi belum tersedia.

Kategori:
Barbiturates, PlainCentral Nervous System DepressantsHypnotics and Sedatives +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allocetra DB16424
biotech

Allocetra is a novel therapy where billions of early apoptotic cells are infused into the bloodstream of a patient, using the body's own natural regulation mechanisms to rebalance an unbalanced immune system without immune system suppression. With infusion, t…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Cardiosphere-derived cells (CDCs) are derived from human neonatal heart tissue with a distinct antigenic profile (CD105+, CD45-, and CD90low). They exert their effects by secreting exosomes: nanometer-sized, membrane-bound vesicles used for the purpose of cel…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention…

Kategori:
FibroblastsKeratinocytes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Allogeneic processed thymus tissue is used for immune reconstitution in immune disorders where the patients are severely immunocompromised due to the absence of a functional thymus, such as congenital athymia. As part of the immune system, the thymus is an or…

Waktu ParuhThe pharmacokinetic…
Vol. DistribusiThe pharmacokinetic…
KlirensThe pharmacokinetic…
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other …

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Umbilical-cord derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and anti-inflammatory properties. In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and genera…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Human olfactory mucosa-derived mesenchymal stem cells (OM-MSCs) reside in an accessible location of the nasal cavity and have properties of multipotency and high proliferation, which contributes to high potential for regenerative medicine. In humans, OM-MSCs …

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alloin Approved DB15477
small molecule | CAS: 8015-61-0

Deskripsi belum tersedia.

Kategori:
AnthracenesAnthraquinonesBiological Products +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allolactose DB04116
small molecule | CAS: 645-03-4

Deskripsi belum tersedia.

Kategori:
CarbohydratesDisaccharidesOligosaccharides +1
Target Protein:
Beta-galactosidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allopurinol Approved DB00437
small molecule | CAS: 315-30-0

Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints [A175942]. This disease has been well-documented in historical medical records and appears in the biographies of several prominent, h…

Kategori:
Antigout PreparationsAntimetabolitesAntioxidants +12
Target Protein:
Xanthine dehydrogenase/oxidase
Gen Terkait:
HCP5
Waktu ParuhThe plasma half-lif…
Vol. DistribusiAllopurinol and oxy…
KlirensSince allopurinol a…
Genetik 1 Varian
small molecule | CAS: 16220-07-8

Allopurinol riboside is a nucleoside analogue of [allopurinol] with a beta-D-ribofuranosyl moiety at the 1-position.

Kategori:
Anti-Infective AgentsAntiparasitic AgentsAntiprotozoals +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allosamidin DB04628
small molecule | CAS: 103782-08-7

Allosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from <i>Candida albicans</i>, and can be utilized as potent antifungal agent.

Kategori:
AgrochemicalsAmino SugarsCarbohydrates +9
Target Protein:
Chitinase BChitinase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allosamizoline DB04404
small molecule

Deskripsi belum tersedia.

Kategori:
Amino SugarsCarbohydratesChitinases +1
Target Protein:
Chitotriosidase-1Chitinase BChitinase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allovectin-7 DB17439
biotech | CAS: 190857-15-9

Allovectin-7 or allovectin-7(r) is a lipid complex that contains the DNA sequences encoding HLA-B7 and beta-2 microglobulin. It was discontinued after it failed to improve the objective response rate or overall survival versus first-line chemotherapy in malig…

Kategori:
LiposomesNucleic AcidsNucleic Acids, Nucleotides, and Nucleosides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allspice Approved DB10669
biotech

Allspice allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Squalene--hopene cyclase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Squalene--hopene cyclase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allylestrenol DB01431
small molecule | CAS: 432-60-0

A synthetic steroid with progestational activity. It is widely marketed throughout Europe, including Russia and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though notably …

Kategori:
Adrenal Cortex HormonesCytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 Substrates +13
Target Protein:
Progesterone receptorSodium- and chloride-dependent glycine transporter 1Estrogen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allylprodine DB01542
small molecule | CAS: 25384-17-2

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Allysine DB02571
small molecule | CAS: 6665-12-9

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAdipatesAmino Acids +3
Target Protein:
Glutaminase-asparaginase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ALM201 DB17206
biotech

ALM201 is an anti-angiogenic synthetic peptide identified from the endogenous human protein, FKBPL. It is being investigated in the treatment of various cancers.[A254556]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Almasilate Approved DB13595
small molecule | CAS: 71205-22-6

Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. However its therapeutic effic…

Kategori:
Alimentary Tract and MetabolismAluminum and magnesium containing antacidsAntacids +6
Waktu ParuhReadily accessible …
Vol. DistribusiThe distribution of…
KlirensReadily accessible …
Genetik -
ALMB-0166 DB17937
biotech

ALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of acute spinal cord injury. It was granted FDA orphan designation in November 2018.[L47067]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ALMB-0168 DB16926
biotech

ALMB-0168 is a humanized connexin 43 (Cx43) monoclonal antibody being investigated for osteosarcoma.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alminoprofen DB13314
small molecule | CAS: 39718-89-3

Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.

Kategori:
Acids, AcyclicAgents causing hyperkalemiaAgents that produce hypertension +16
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Almitrine Approved DB01430
small molecule | CAS: 27469-53-0

Almitrine is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. It is used in the treatment of chronic obstructive pulmonary disease. It is also reported to have a potentially …

Kategori:
AlkaloidsCentral Nervous System AgentsCompounds used in a research, industrial, or household setting +12
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Almond Approved DB10500
biotech

Almond allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Almonertinib DB16640
small molecule | CAS: 1899921-05-1

Almonertinib is a third-generation EGFR tyrosine kinase inhibitor targeting EGFR-sensitizing and T790M resistance mutations.[A231859, A231864, A231869] It is being investigated against advanced or metastatic EGFR-mutated non-small cell lung cancer (NSCLC).[A2…

Kategori:
Acids, AcyclicAcrylatesAmides +1
Target Protein:
Epidermal growth factor receptorReceptor protein-tyrosine kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Almorexant DB06673
small molecule | CAS: 871224-64-5

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAmides +1
Target Protein:
Orexin/Hypocretin receptor type 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Almotriptan Approved DB00918
small molecule | CAS: 154323-57-6

Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain,…

Kategori:
Agents that produce hypertensionAminesAnalgesics +30
Target Protein:
5-hydroxytryptamine receptor 1D5-hydroxytryptamine receptor 1B
Gen Terkait:
GNB3
Waktu Paruh3-4 hours
Vol. Distribusi* 180 to 200 L
Klirens* 57 L/h [healthy] …
Genetik 1 Varian
Alnuctamab DB17194
biotech | CAS: 2296827-07-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alnus glutinosa DB15904
biotech

Deskripsi belum tersedia.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Alnus incana subsp. rugosa pollen is the pollen of the Alnus incana subsp. rugosa plant. Alnus incana subsp. rugosa pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alnus rhombifolia pollen Approved DB10722
biotech

Alnus rhombifolia pollen is the pollen of the Alnus rhombifolia plant. Alnus rhombifolia pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alnus rubra pollen Approved DB10721
biotech

Alnus rubra pollen is the pollen of the Alnus rubra plant. Alnus rubra pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alnus serrulata pollen Approved DB15509
biotech

Alnus serrulata pollen allergenic extract is used in allergenic testing.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 3101–3150 dari 17430
Sebelumnya Halaman 63 / 349 Berikutnya