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6694

Total database: 17430
Struktur (SMILES)
4518 (67.5%)
Target
3751 (56.0%)
Genomik
81 (1.2%)
Referensi
6694 (100.0%)

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Hasil Pencarian (6694)

Halaman 63 / 134
biotech

Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is a vaccine for intramuscular injection used in the prevention of invasive disease caused by *Haemophilus influenzae* type b. *H. influenzae* is a Gram-negativ…

Kategori:
Actively Acquired ImmunityHaemophilus VaccinesInactivated Haemophilus Influenzae B Vaccine
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vacci…

Kategori:
Actively Acquired ImmunityHaemophilus VaccinesInactivated Haemophilus Influenzae B Vaccine +2
Waktu Paruh-
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Genetik -
Halcinonide Approved DB06786
small molecule | CAS: 3093-35-4

Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Labora…

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroid Hormone Receptor Agonists +13
Target Protein:
Steroid hormone receptor ERR1Steroid hormone receptor ERR2Estrogen-related receptor gamma +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Halicin DB15624
small molecule | CAS: 40045-50-9

Deskripsi belum tersedia.

Kategori:
Sulfur CompoundsThiazoles
Target Protein:
c-Jun N-terminal kinases
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Halofantrine Approved DB01218
small molecule | CAS: 69756-53-2

Halofantrine is an antimalarial. It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine. It appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting in the parasite being poiso…

Kategori:
Agents that reduce seizure thresholdAnti-Infective AgentsAntimalarials +13
Target Protein:
Fe(II)-protoporphyrin IXCalmodulin-1Calmodulin-3 +3
Waktu Paruh6-10 days
Vol. Distribusi-
Klirens-
Genetik -
Haloperidol Approved DB00502
small molecule | CAS: 52-86-8

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide.[A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain,[A274…

Kategori:
Agents that reduce seizure thresholdAnti-Dyskinesia AgentsAntidepressive Agents +50
Target Protein:
5-hydroxytryptamine receptor 2CD(2) dopamine receptor5-hydroxytryptamine receptor 2A +15
Waktu ParuhFollowing oral admi…
Vol. DistribusiThe apparent volume…
KlirensFollowing intraveno…
Genetik -
Haloprogin Approved DB00793
small molecule | CAS: 777-11-7

Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Com…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Halothane Approved DB01159
small molecule | CAS: 151-67-7

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxatio…

Kategori:
Agents that produce hypertensionAnestheticsAnesthetics, General +14
Target Protein:
Potassium channel subfamily K member 3Potassium channel subfamily K member 9GABA(A) Receptor +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Haloxyfop-P DB07870
small molecule | CAS: 95977-29-0

Deskripsi belum tersedia.

Target Protein:
Acetyl-CoA carboxylase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
AngiospermsBiological ProductsComplex Mixtures +10
Waktu Paruh-
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Genetik -
Hazelnut Approved DB10654
biotech

Hazelnut allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

Heat stable ricin vaccine is an alum-adjuvanted, heat stable recombinant subunit vaccine.

Waktu Paruh-
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biotech

Hedera helix leaf extract allergenic extract is used in allergenic testing.

Kategori:
Cough and Cold PreparationsExpectorants
Waktu Paruh-
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Hemin Approved DB03404
biotech | CAS: 16009-13-5

Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.

Kategori:
Biological FactorsBlood and Blood Forming OrgansHeme +5
Target Protein:
5-aminolevulinate synthase, non-specific, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 142261-03-8

Hemoglobin in which the alpha-subunit are cross-linked intramolecularly.

Kategori:
Amino Acids, Peptides, and ProteinsBenzene DerivativesBlood and Blood Forming Organs +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heparin Approved DB01109
small molecule | CAS: 9005-49-6

Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III …

Kategori:
Agents causing hyperkalemiaAnticoagulantsAntivaricose Therapy +16
Target Protein:
Antithrombin-IIICoagulation factor XP-selectin +9
Waktu ParuhThe plasma half-lif…
Vol. DistribusiThe volume of distr…
KlirensThe clearance in ad…
Genetik -
Hepatitis A Vaccine Approved DB10989
biotech

Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure.[A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has bee…

Kategori:
Actively Acquired ImmunityBiological ProductsComplex Mixtures +4
Target Protein:
B-lymphocytes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
Hepatitis B immune globulin Approved DB05276
biotech

Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatit…

Kategori:
Amino Acids, Peptides, and ProteinsAntiinfectives for Systemic UseBlood Proteins +12
Target Protein:
HBsAg
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. …

Kategori:
Actively Acquired ImmunityAmino Acids, Peptides, and ProteinsAntigens +19
Waktu ParuhEvaluation of pharm…
Vol. DistribusiEvaluation of pharm…
KlirensEvaluation of pharm…
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBlood ProteinsGlobulins +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hepcidin-25 DB19226
biotech | CAS: 1356390-47-0

Hepcidin-25 is under investigation in clinical trial NCT03381833 (A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-dependent Beta Thalassemia).

Waktu Paruh-
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HEPES DB16872
small molecule | CAS: 7365-45-9

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonic AcidsBuffers +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Heptanoic acid DB02938
small molecule | CAS: 111-14-8

Deskripsi belum tersedia.

Target Protein:
Phospholipase A2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hesperidin Approved DB04703
small molecule | CAS: 520-26-3

Hesperidin is a flavan-on glycoside found in citrus fruits.

Kategori:
BenzopyransCarbohydratesChromones +5
Target Protein:
Voltage-dependent N-type calcium channel subunit alpha-1BAurora kinase B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hetacillin Approved DB00739
small molecule | CAS: 3511-16-8

Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of ant…

Kategori:
AmidesAnti-Bacterial AgentsAntibacterials for Systemic Use +8
Target Protein:
Penicillin-binding protein 2aPenicillin-binding protein 1bPenicillin-binding protein 3 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 29710-31-4

Deskripsi belum tersedia.

Target Protein:
HTH-type transcriptional regulator EthR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexamethonium DB08960
small molecule | CAS: 60-26-4

A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hyp…

Kategori:
AminesAnticholinergic AgentsAntihypertensive Agents +14
Target Protein:
Neuronal acetylcholine receptor subunit alpha-2Dihydroorotate dehydrogenase (quinone), mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexaminolevulinate Approved DB06261
small molecule | CAS: 140898-97-1

Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approv…

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsCarbon Radioisotopes +5
Waktu ParuhBiphasic eliminatio…
Vol. Distribusi-
Klirens-
Genetik -
Hexetidine Approved DB08958
small molecule | CAS: 141-94-6

A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.

Kategori:
Alimentary Tract and MetabolismAnti-Infective AgentsAnti-Infective Agents, Local +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexobarbital DB01355
small molecule | CAS: 56-29-1

A barbiturate that is effective as a hypnotic and sedative.

Kategori:
AdjuvantsAnestheticsAnesthetics, General +18
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-3Gamma-aminobutyric acid receptor subunit alpha-4 +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lipase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lipase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hexylresorcinol Approved DB11254
small molecule | CAS: 136-77-6

Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid …

Kategori:
AnthelminticsAnti-Infective AgentsAnti-Infective Agents, Local +6
Target Protein:
TyrosinaseDNA topoisomerase 1Protein-glutamine gamma-glutamyltransferase 2
Waktu ParuhReadily accessible …
Vol. DistribusiReadily accessible …
KlirensReadily accessible …
Genetik -
HG004 DB18666
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HGS-TR2J DB05895
biotech

HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies. It is developed by Human Genome Sciences, Inc and is under Phase I of clinical trial.

Target Protein:
Tumor necrosis factor receptor superfamily member 10B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
HH-009 DB18727
biotech

HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.

Waktu Paruh-
Vol. Distribusi-
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Hiltonol DB17293
biotech | CAS: 59789-29-6

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicAmino AcidsAmino Acids, Basic +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hippuric acid DB16842
small molecule | CAS: 495-69-2

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzamides and benzamide derivatives +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histidine DB00117
small molecule | CAS: 71-00-1

An essential amino acid that is required for the production of histamine.

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Essential +4
Target Protein:
Histidine decarboxylaseHistidine--tRNA ligase, cytoplasmicSodium-coupled neutral amino acid transporter 3 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Histrelin Approved DB06788
small molecule | CAS: 76712-82-8

Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher pot…

Kategori:
Adrenal Cortex HormonesAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +17
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe apparent volume…
KlirensIn prostate cancer …
Genetik -
HMI-103 DB17684
biotech

HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
HMI-203 DB18520
biotech

HMI-203 is an investigational gene therapy developed by Homology Medicines, Inc. It consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate-2-sulfatase (hIDS).

Waktu Paruh-
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HMI-204 DB18338
biotech

HMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Homatropine methylbromide Approved DB00725
small molecule | CAS: 80-49-9

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAlkaloids +7
Target Protein:
Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M4 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Homidium DB17031
small molecule | CAS: 3546-21-2

Homidium is a group II compound with trypanocidal effects.[A253017]

Kategori:
Anti-Infective AgentsAnticholinergic AgentsAntiparasitic Agents +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 848-53-3

Deskripsi belum tersedia.

Kategori:
Piperazines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Homocysteine DB04422
small molecule | CAS: 6027-13-0

Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +1
Target Protein:
S-ribosylhomocysteine lyase5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase5-methyltetrahydrofolate S-homocysteine methyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 451-13-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicPhenylacetates
Target Protein:
Penicillin G acylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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