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14494

Total database: 17430
Struktur (SMILES)
9687 (66.8%)
Target
7525 (51.9%)
Genomik
112 (0.8%)
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14494 (100.0%)

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Hasil Pencarian (14494)

Halaman 60 / 290
small molecule | CAS: 17499-98-8

A specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A.

Kategori:
Amino Acids, Peptides, and ProteinsBacteriochlorophyllsHeterocyclic Compounds, Fused-Ring +2
Target Protein:
Bacteriochlorophyll a proteinBacteriochlorophyll a protein
Waktu Paruh-
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Genetik -
biotech

Bacteroides thetaiotaomicron is a live biotherapeutic. Developed by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.[A259892]

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BacTRL-spike DB15811
biotech

BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum engineered to deliver synthetic DNA encoding spike protein from SARS-CoV-2 contained by plasmids. The vaccine was developed by Symvivo Corporation. As of J…

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Bafetinib DB11851
small molecule | CAS: 859212-16-1

Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.

Kategori:
Enzyme InhibitorsProtein Kinase Inhibitors
Target Protein:
Tyrosine-protein kinase Lyn
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Bafilomycin A1 DB06733
small molecule | CAS: 88899-55-2

The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins are specific inhibitors of vacuolar-type H…

Kategori:
Anti-Infective AgentsAntifungal AgentsEnzyme Inhibitors +3
Target Protein:
V-type proton ATPase catalytic subunit A
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Bafilomycin B1 DB06734
small molecule | CAS: 88899-56-3

Deskripsi belum tersedia.

Kategori:
LactonesPolyketides
Target Protein:
V-type proton ATPase catalytic subunit A
Waktu Paruh-
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Baicalein DB16101
small molecule | CAS: 491-67-8

Baicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ?A Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of Improve Other Aspects of Healthy …

Kategori:
AntioxidantsBenzopyransBiological Factors +11
Target Protein:
Lactoylglutathione lyaseTumor necrosis factorXanthine dehydrogenase/oxidase +4
Waktu Paruh-
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Bakuchiol DB16102
small molecule | CAS: 10309-37-2

Bakuchiol is under investigation in clinical trial NCT03112863 (Comparison of the Cosmetic Effects of Bakuchiol and Retinol).

Kategori:
Benzene Derivatives
Waktu Paruh-
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Balapiravir DB12283
small molecule | CAS: 690270-29-2

Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic.

Kategori:
CarbohydratesGlycosidesNucleic Acids, Nucleotides, and Nucleosides
Target Protein:
Genome polyprotein
Waktu Paruh-
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Balhimycin DB04111
small molecule | CAS: 140932-79-2

Balhimycin is a novel glycopeptide antibiotic.

Kategori:
Amino Acids, Peptides, and ProteinsCarbohydratesGlycoconjugates +2
Waktu Paruh-
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Balicatib DB12239
small molecule | CAS: 354813-19-7

Balicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +1
Target Protein:
Cathepsin K
Waktu Paruh-
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Balipodect DB14774
small molecule | CAS: 1238697-26-1

Balipodect is under investigation in clinical trial NCT01892189 (Effects of TAK-063 on Preventing Ketamine-Induced Brain Activity Changes as Well as Psychotic-Like Symptoms in Healthy Male Adults).

Target Protein:
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Waktu Paruh-
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Balixafortide DB15370
biotech | CAS: 1051366-32-5

Balixafortide is under investigation in clinical trial NCT03786094 (Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
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Baloramotide DB17986
biotech | CAS: 2207581-19-7

Deskripsi belum tersedia.

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Balovaptan DB14823
small molecule | CAS: 1228088-30-9

Balovaptan is under investigation in clinical trial NCT01793441 (A Study of RG7314 to Investigate Efficacy and Safety in Individuals With Autism Spectrum Disorders (ASD)).

Kategori:
Antidiuretic Hormone Receptor AntagonistsBenzazepinesHeterocyclic Compounds, Fused-Ring +1
Target Protein:
Vasopressin V1a receptor
Waktu Paruh-
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Genetik -
Baloxavir DB15675
small molecule | CAS: 1985605-59-1

Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).

Kategori:
Anti-Infective AgentsAntiviral AgentsBaloxavir and prodrugs +8
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Baloxavir marboxil Approved DB13997
small molecule | CAS: 1985606-14-1

Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +25
Target Protein:
Polymerase acidic protein
Waktu ParuhThe apparent termin…
Vol. DistribusiThe volume of distr…
KlirensClearance of baloxa…
Genetik -
Balsalazide Approved DB01014
small molecule | CAS: 80573-04-2

Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenz…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +27
Target Protein:
Peroxisome proliferator-activated receptor gammaProstaglandin G/H synthase 2Prostaglandin G/H synthase 1 +1
Waktu ParuhHalf-life could not…
Vol. Distribusi-
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Balsam of Peru DB11482
small molecule | CAS: 8007-00-9

Balsam of Peru is a resin that comes from the tree Myroxylon balsamum pereirae. It is constituted by a mixture of substances from which the major components are benzyl cinnamate and [DB00676]. Balsam of Peru has also presented several allergens such as cinnam…

Kategori:
Biological ProductsBiopolymersCell-mediated Immunity +8
Waktu ParuhThis pharmacokineti…
Vol. DistribusiThis pharmacokineti…
KlirensThis pharmacokineti…
Genetik -
Baltaleucel-T DB19145
biotech

Deskripsi belum tersedia.

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Bambermycins DB11377
small molecule | CAS: 11015-37-5

Bambermycins are antibiotic complexes which are retrieved from the organism, _Streptomyces bambergiensis_. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics consists primarily of moenomycins A and C.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntigens +5
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biotech

Deskripsi belum tersedia.

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biotech

Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Bambuterol DB01408
small molecule | CAS: 81732-65-2

Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.

Kategori:
Adrenergic AgonistsAdrenergic beta-2 Receptor AgonistsAdrenergic beta-Agonists +20
Target Protein:
Beta-2 adrenergic receptorCholinesterase
Waktu Paruh13 hours for bambut…
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Bamet-UD2 DB08857
small molecule

Bamet-UD2 is a novel bile acid-platinum derivative.

Kategori:
Bile Acids and SaltsCholanesCholic Acids +3
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Bamifylline DB13203
small molecule | CAS: 2016-63-9

Bamifylline is a selective A1 adenosine receptor antagonist.

Kategori:
AlkaloidsAnalgesicsAnti-Asthmatic Agents +15
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Baminercept DB06576
biotech | CAS: 909110-25-4

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsProteinsRecombinant Proteins
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Bamlanivimab Approved DB15718
biotech | CAS: 2423943-37-5

Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of the first blood samples in the United States from a patient who recovered from COVID-19.[A224039, L15311, L15316] Bamlanivimab is a neutralizing Ig…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntibodies +10
Target Protein:
Spike glycoprotein
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Bamocaftor DB15177
small molecule | CAS: 2204245-48-5

Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis).

Kategori:
Chloride Channel AgonistsMembrane Transport Modulators
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Bamosiran DB12256
biotech | CAS: 1337968-84-9

Bamosiran has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, and Open Angle Glaucoma.

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Banana Approved DB10505
biotech

Banana allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Banoxantrone DB04975
small molecule | CAS: 136470-65-0

Banoxantrone is a highly selective bioreductive drug that is activated in, and is preferentially toxic to, hypoxic cells in tumours. It has been shown to work synergistically with fractionated radiation to significantly delay growth of tumours compared to adm…

Kategori:
AnthracenesAntineoplastic AgentsCytochrome P-450 CYP2B6 Substrates +4
Target Protein:
DNA topoisomerase 2-betaDNA topoisomerase 2-alpha
Waktu Paruh0.64 to 0.83 hours
Vol. Distribusi-
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Barbexaclone DB09001
small molecule | CAS: 4388-82-3

Barbexaclone, a salt compound of propylhexedrine and phenobarbital, is a potent antiepileptic. By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. While barbexaclone has sedative properties, propylhexedrine has psychostimulant properties in…

Kategori:
AnticonvulsantsBarbituratesBarbiturates and Derivatives +8
Waktu ParuhAfter IV administra…
Vol. DistribusiIn mice, the volume…
Klirens-
Genetik -
Barbital DB01483
small molecule | CAS: 57-44-3

A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice for central nervous system depression. Barbital is a schedule IV con…

Kategori:
Anticholinergic AgentsAnticonvulsantsBarbiturates +20
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Gamma-aminobutyric acid receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-3 +7
Waktu Paruh-
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Bardoxolone DB12651
small molecule | CAS: 218600-44-3

Bardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors. It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in cancer cells that are …

Kategori:
Pentacyclic TriterpenesSapogeninsTerpenes +1
Target Protein:
Nitric oxide synthase, inducibleCaspase-8
Waktu Paruh-
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Barecetamab DB17479
biotech | CAS: 2275727-74-5

Deskripsi belum tersedia.

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Baricitinib Approved DB11817
small molecule | CAS: 1187594-09-7

Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the …

Kategori:
AmidesAntineoplastic and Immunomodulating AgentsAntirheumatic Agents +31
Target Protein:
Tyrosine-protein kinase JAK1Tyrosine-protein kinase JAK2Tyrosine-protein kinase JAK3 +1
Waktu ParuhThe elimination hal…
Vol. DistribusiFollowing intraveno…
KlirensThe total body clea…
Genetik -
Barium DB12481
small molecule | CAS: 7440-39-3

Barium is under investigation for the diagnostic of Known or Suspected Abdominal Disease.

Kategori:
ElementsMetalsMetals, Alkaline Earth +1
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Barium sulfate Approved DB11150
small molecule | CAS: 7727-43-7

Barium sulfate is an inorganic compound with the chemical formula BaSO4 [L1957]. Barium sulfate occurs in nature as the mineral _barite_. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield [L1…

Kategori:
Barium CompoundsBarium Sulfate Containing X-Ray Contrast MediaCompounds used in a research, industrial, or household setting +9
Waktu Paruh-
Vol. Distribusi-
KlirensThe rate of excreti…
Genetik -
Barley Approved DB10506
biotech

Barley allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Barley malt Approved DB10980
biotech

Barley malt allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
Waktu Paruh-
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Genetik -
Barley malt syrup Approved DB14601
biotech

Barley malt syrup allergenic extract is used in allergenic testing.

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Barnidipine DB09227
small molecule | CAS: 104713-75-9

Barnidipine is a long-acting novel calcium antagonist that belongs to the dihydropyridine (DHP) group of calcium channel blockers. Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the smooth muscle cells in…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsBradycardia-Causing Agents +17
Target Protein:
Voltage-dependent L-type calcium channel subunit alpha-1CVoltage-dependent T-type calcium channel subunit alpha-1GVoltage-dependent T-type calcium channel subunit alpha-1H
Waktu ParuhIn a two-compartmen…
Vol. DistribusiAfter administratio…
Klirens-
Genetik -
Barzolvolimab DB18934
biotech | CAS: 2438203-51-9

Barzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).

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biotech | CAS: 106096-93-9

Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. Several different forms of the human protein exist ranging fro…

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsFibroblast Growth Factor 2, antagonists & inhibitors +4
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Basifungin DB14058
small molecule | CAS: 127785-64-2

Basifungin, also known as _aureuobacidin A_, is a phosphorylceramide synthase inhibitor [L2960], [A33381].

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntifungal Agents +3
Target Protein:
Inositol phosphorylceramide synthase
Waktu Paruh-
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Basil Approved DB10829
biotech

Basil allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
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Basiliximab Approved DB00074
biotech | CAS: 179045-86-4

A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lym…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +14
Target Protein:
Interleukin-2 receptor subunit alphaInterleukin-2 receptor subunit beta
Waktu Paruh7.2 +/- 3.2 days (a…
Vol. Distribusi* 7.8 ± 5.1 L [Pedi…
Klirens* 41 +/- 19 mL/h [A…
Genetik -
Basimglurant DB11833
small molecule | CAS: 802906-73-6

Basimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome, and Major Depressive Disorder.

Target Protein:
Metabotropic glutamate receptor 5
Waktu Paruh-
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Basmisanil DB11877
small molecule | CAS: 1159600-41-5

Basmisanil has been used in trials studying the treatment and basic science of Down Syndrome.

Kategori:
Oxazines
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-5
Waktu Paruh-
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Genetik -
Menampilkan 2951–3000 dari 14494
Sebelumnya Halaman 60 / 290 Berikutnya