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11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

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Hasil Pencarian (11778)

Halaman 56 / 236
Bergamot oil DB14335
biotech | CAS: 8007-75-8

Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Biological ProductsComplex MixturesCompounds used in a research, industrial, or household setting +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berkelium DB12993
small molecule | CAS: 7440-40-6

Berkelium is under investigation in clinical trial NCT02189122 (Comparative Effects of Aspirin and NHP-544C).

Kategori:
Actinoid Series ElementsElementsElements, Radioactive +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bermekimab DB14947
biotech | CAS: 1401965-15-8

Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beroctocog alfa Approved DB14473
biotech | CAS: 9001-27-8

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berotralstat Approved DB15982
small molecule | CAS: 1809010-50-1

Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE).[L26661] It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that pro…

Kategori:
BCRP/ABCG2 SubstratesBlood and Blood Forming OrgansCytochrome P-450 CYP2D6 Inhibitors +16
Target Protein:
Plasma kallikrein
Waktu ParuhFollowing a single …
Vol. DistribusiThe blood to plasma…
KlirensThere is no informa…
Genetik -
Bersacapavir DB19035
small molecule | CAS: 1638266-40-6

Bersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).

Kategori:
Anti-Infective AgentsAntiviral Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bersanlimab DB17377
biotech | CAS: 1987854-08-9

Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bersiporocin DB18017
small molecule | CAS: 2241808-52-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berubicin DB17149
small molecule | CAS: 677017-23-1

Deskripsi belum tersedia.

Kategori:
Aminoglycoside AntibacterialsAnti-Bacterial AgentsCarbohydrates +2
Target Protein:
DNA topoisomerase 2-alphaDNA topoisomerase 2-beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berzosertib DB11794
small molecule | CAS: 1232416-25-9

Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.

Target Protein:
Serine/threonine-protein kinase ATR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Besifloxacin Approved DB06771
small molecule | CAS: 141388-76-3

Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +16
Target Protein:
DNA topoisomerase 4 subunit ADNA gyrase subunit BDNA gyrase subunit A +3
Waktu ParuhThe average elimina…
Vol. DistribusiNot absorbed into t…
KlirensN/A
Genetik -
Besifovir DB15671
small molecule | CAS: 441785-25-7

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingOrganophosphorus CompoundsPurines +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 441785-26-8

Besifovir dipivoxil is a small-molecule orally available inhibitor of the HBV polymerase. The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of RNA. Besifovir dipivoxil is believed to inhibit viral proliferation…

Kategori:
Heterocyclic Compounds, Fused-RingOrganophosphorus CompoundsPurines +2
Target Protein:
Protein P
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Besilesomab Approved DB13979
biotech | CAS: 537694-98-7

Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
Carcinoembryonic antigen
Waktu ParuhWhole blood concent…
Vol. DistribusiIn the besilesomab …
KlirensOnce administered i…
Genetik -
Beta carotene Approved DB06755
small molecule | CAS: 7235-40-7

Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors.[T162] It is the most abundant form of carote…

Kategori:
Alimentary Tract and MetabolismAlkenesBiological Factors +20
Target Protein:
Free radicals
Waktu ParuhThe apparent half-l…
Vol. DistribusiNo pharmacokinetic …
KlirensThe clearance rate …
Genetik -
Beta vulgaris pollen Approved DB10837
biotech

Beta vulgaris pollen is the pollen of the Beta vulgaris plant. Beta vulgaris pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 9051-97-2

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicCarbohydratesExperimental Unapproved Treatments for COVID-19 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1ProthrombinTyrosine--tRNA ligase, cytoplasmic
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 22951-96-8

Deskripsi belum tersedia.

Target Protein:
Phenylalanine-4-hydroxylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beta-3-Cysteine DB02780
small molecule

Deskripsi belum tersedia.

Target Protein:
Envelope glycoprotein gp160
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Alanine DB03107
small molecule | CAS: 107-95-9

beta-Alanine is an amino acid formed in vivo by the degradation of [dihydrouracil] and [carnosine]. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBU…

Kategori:
AlanineAmino AcidsAmino Acids, Peptides, and Proteins
Target Protein:
Sodium- and chloride-dependent GABA transporter 3Pantothenate synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 477-52-1

beta-Apopicropodophyllin is a component of the freshwater plant _Micranthemum umbrosum_.

Kategori:
Biological ProductsComplex MixturesPlant Extracts +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Ribose-5-phosphate isomerase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7660-25-5

Deskripsi belum tersedia.

Target Protein:
Fucose-binding lectin PA-IIL
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
CarbohydratesOligosaccharidesPolysaccharides
Target Protein:
Arabinogalactan endo-beta-1,4-galactanase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 14196-86-2

Deskripsi belum tersedia.

Target Protein:
Galectin-7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beta-D-Glucose DB02379
small molecule | CAS: 492-61-5

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

Kategori:
CarbohydratesGlucosidesGlycosides +2
Target Protein:
Neutral alpha-glucosidase ABNeutral alpha-glucosidase CHexokinase-4 +91
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7296-60-8

Deskripsi belum tersedia.

Target Protein:
Angiotensin-converting enzymeRibose import binding protein RbsBD-ribose pyranase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Escin DB15774
small molecule | CAS: 26339-90-2

Deskripsi belum tersedia.

Kategori:
CarbohydratesCardiovascular AgentsGlycosides +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 20790-72-1

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +2
Target Protein:
Mannan-binding lectin serine protease 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 300-85-6

Beta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236 (completed for type 1 diabetes), and NCT0558104…

Kategori:
Acids, AcyclicButyratesExperimental Unapproved Treatments for COVID-19 +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 78995-10-5

Deskripsi belum tersedia.

Kategori:
Piperidines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Peptides, and Proteins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24915-04-6

Deskripsi belum tersedia.

Kategori:
AlkaloidsAntiarrhythmic agentsCardiovascular Agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7296-56-2

Deskripsi belum tersedia.

Target Protein:
L-arabinose-binding periplasmic protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Mannobiose DB01687
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6051-87-2

?-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.

Kategori:
BenzoflavonesBenzopyransChromones +7
Target Protein:
Estrogen receptorSteroid hormone receptor ERR1COUP transcription factor 1 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Prothrombin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Pinene DB15574
small molecule | CAS: 127-91-3

Deskripsi belum tersedia.

Kategori:
Bridged-Ring CompoundsMonoterpenesTerpenes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 17199-59-6

A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betadex DB03995
small molecule | CAS: 7585-39-9

Deskripsi belum tersedia.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingCyclodextrins +15
Target Protein:
Neopullulanase 2Maltose-binding periplasmic proteinMaltogenic amylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betahistine Approved DB06698
small molecule | CAS: 5638-76-6

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-l…

Kategori:
Antivertigo PreparationsHistamine AgentsHistamine Agonists +7
Target Protein:
Histamine H1 receptorHistamine H3 receptor
Waktu ParuhThe half-life of be…
Vol. DistribusiIn a pharmacokineti…
Klirens-
Genetik -
Betaine Approved DB06756
small molecule | CAS: 107-43-7

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252…

Kategori:
Acid PreparationsAlimentary Tract and MetabolismAmines +12
Target Protein:
Betaine--homocysteine S-methyltransferase 1
Waktu ParuhIn healthy voluntee…
Vol. DistribusiBased on a study do…
KlirensBased on a study do…
Genetik -
small molecule | CAS: 7418-61-3

Deskripsi belum tersedia.

Kategori:
AminesOnium CompoundsQuaternary Ammonium Compounds +1
Target Protein:
Gamma-aminobutyraldehyde dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betamethasone Approved DB00443
small molecule | CAS: 378-44-9

Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.[A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmu…

Kategori:
Adrenal Cortex HormonesAdrenalsAgents Causing Muscle Toxicity +52
Target Protein:
Glucocorticoid receptor
Waktu ParuhIn a study that inc…
Vol. DistribusiIn a study that inc…
KlirensIn a study that inc…
Genetik -
Betaprodine DB01473
small molecule | CAS: 468-59-7

An opioid analgesic chemically related to and with an action resembling that of meperidine, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures.…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betaxolol Approved DB00195
small molecule | CAS: 63659-18-7

A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-1 Receptor Antagonists +28
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptor
Waktu Paruh14-22 hours
Vol. Distribusi-
Klirens-
Genetik -
Betazole Approved DB00272
small molecule | CAS: 105-20-4

A histamine H2 agonist used clinically to test gastric secretory function.

Kategori:
Diagnostic AgentsGastrointestinal AgentsHistamine Agents +4
Target Protein:
Histamine H2 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bethanechol Approved DB01019
small molecule | CAS: 674-38-4

Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympat…

Kategori:
Acids, AcyclicAminesAmmonium Compounds +16
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M5Muscarinic acetylcholine receptor M1 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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