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12560

Total database: 17430
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9109 (72.5%)
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6912 (55.0%)
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109 (0.9%)
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12560 (100.0%)

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Hasil Pencarian (12560)

Halaman 56 / 252
Azenosertib DB18028
small molecule | CAS: 2376146-48-2

Deskripsi belum tersedia.

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biotech

Deskripsi belum tersedia.

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Azficel-T Approved DB11051
biotech

Azficel-T is an autologous cellular product composed of fibroblasts indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. Dermal fibroblasts are collected from the post-auricular biopsy tissue and aseptically ex…

Kategori:
Autologous Cultured Cell
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Azidocillin DB08795
small molecule | CAS: 17243-38-8

Azidocillin is a penicillin antibiotic similir to ampicillin.

Kategori:
AmidesAnti-Bacterial AgentsAntibacterials for Systemic Use +8
Target Protein:
Penicillin-binding protein 2aPenicillin-binding protein 1bPenicillin-binding protein 3 +2
Waktu Paruh-
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Azilsartan medoxomil Approved DB08822
small molecule | CAS: 863031-21-4

Azilsartan medoxomil is a prodrug that is broken down to azilsartan, which belongs in the angiotensin-receptor blocking (ARB) drug class. It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed…

Kategori:
Agents Acting on the Renin-Angiotensin SystemAgents causing angioedemaAgents causing hyperkalemia +18
Target Protein:
Type-1 angiotensin II receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensRenal clearance of …
Genetik -
Azimilide DB04957
small molecule | CAS: 149908-53-2

Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels. It is not approved for use in any country, but is currently in clinical trials in the United States.

Kategori:
Antiarrhythmic agentsAntiarrhythmics, Class IIICalcium-Regulating Hormones and Agents +11
Target Protein:
Potassium voltage-gated channel subfamily E member 1Potassium voltage-gated channel subfamily KQT member 1Voltage-gated inwardly rectifying potassium channel KCNH2
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biotech | CAS: 1826819-58-2

Azintuxizumab vedotin is under investigation in clinical trial NCT02951117 (A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer Has Come Back or Had No Response to Recent Cancer Treatmen…

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Azithromycin Approved DB00207
small molecule | CAS: 83905-01-5

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175]. It is primarily used for the treatment of respiratory, enteric and genito…

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntibacterials for Systemic Use +22
Target Protein:
23S ribosomal RNAProtein-arginine deiminase type-4
Waktu ParuhTerminal eliminatio…
Vol. DistribusiAfter oral administ…
KlirensMean apparent plasm…
Genetik -
Azlocillin Approved DB01061
small molecule | CAS: 37091-66-0

Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.

Kategori:
Agents that reduce seizure thresholdAmidesAnti-Bacterial Agents +11
Target Protein:
Penicillin-binding protein 1A
Waktu ParuhMean elimination ha…
Vol. Distribusi-
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Azosemide DB08961
small molecule | CAS: 27589-33-9

Azosemide is a loop diuretic used to treat hypertension, edema, and ascites.

Kategori:
AmidesAminesAniline Compounds +7
Waktu ParuhTerminal half life …
Vol. DistribusiPoor affinity for h…
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small molecule | CAS: 892497-01-7

Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).

Kategori:
Macromolecular Substances
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Aztreonam Approved DB00355
small molecule | CAS: 78110-38-0

A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-posit…

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +9
Target Protein:
Penicillin-binding protein 3Peptidoglycan synthase FtsIBeta-lactamase +1
Waktu ParuhThe serum half-life…
Vol. Distribusi* 12.6 L
Klirens* 91 mL/min [health…
Genetik -
Azurin-p28 DB17241
biotech | CAS: 897026-25-4

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBacterial ProteinsMetalloproteins +2
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Azvudine DB16407
small molecule | CAS: 1011529-10-4

Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)).

Kategori:
DeoxyribonucleosidesExperimental Unapproved Treatments for COVID-19Nitrogen Compounds +4
Target Protein:
Broad substrate specificity ATP-binding cassette transporter ABCG2ATP-binding cassette sub-family C member 2ATP-dependent translocase ABCB1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
H subunit of photosynthetic reaction center complexAquaporin ZCytochrome b +6
Waktu Paruh-
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small molecule | CAS: 69984-73-2

Deskripsi belum tersedia.

Target Protein:
Pancreatic triacylglycerol lipaseCytochrome c oxidase subunit 1Cytochrome c oxidase subunit 2 +11
Waktu Paruh-
Vol. Distribusi-
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B27PD DB16289
biotech | CAS: 160387-12-2

B27PD is under investigation in clinical trial NCT01195948 (Optiquel® as Corticosteroid-sparing Therapy for Chronic Noninfectious Uveitis).

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biotech

Deskripsi belum tersedia.

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BA-2664 DB01479
small molecule | CAS: 641-82-7

Deskripsi belum tersedia.

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BA1301 DB19390
biotech

BA1301 is an anti-Claudin18.2 monoclonal antibody conjugated with Duostatin-5.

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Bacampicillin Approved DB01602
small molecule | CAS: 50972-17-3

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbi…

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Target Protein:
Penicillin-binding protein
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Baccharis halimifolia pollen Approved DB10757
biotech

Baccharis halimifolia pollen is the pollen of the Baccharis halimifolia plant. Baccharis halimifolia pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Baccharis sarothroides whole Approved DB15502
biotech

Baccharis sarothroides whole allergenic extract is used in allergenic testing.

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biotech

Deskripsi belum tersedia.

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Bacillus cereus DB19245
biotech | CAS: 68038-62-0

Deskripsi belum tersedia.

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biotech

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biotech | CAS: 68038-65-3

Deskripsi belum tersedia.

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Bacitracin Approved DB00626
small molecule | CAS: 1405-87-4

Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A.[A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named …

Kategori:
Acids, CarbocyclicAmino Acids, Peptides, and ProteinsAnti-Bacterial Agents +19
Target Protein:
C55-isoprenyl pyrophosphateInsulin-degrading enzymeAlpha-2-macroglobulin
Waktu ParuhData regarding the …
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik -
Baclofen Approved DB00181
small molecule | CAS: 1134-47-0

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patie…

Kategori:
Agents Causing Muscle ToxicityAmino AcidsAmino Acids, Peptides, and Proteins +15
Target Protein:
Gamma-aminobutyric acid type B receptor subunit 2C-X-C chemokine receptor type 4Gamma-aminobutyric acid type B receptor subunit 1
Waktu ParuhThe half-life is 2-…
Vol. DistribusiThe volume of distr…
KlirensThe systemic cleara…
Genetik -
BACTEK-R DB16526
biotech

MV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that are involved in upper and lower respiratory infections. These include streptococcus pneumoniae and staphylococcus aureus. Though studies have shown that it…

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small molecule | CAS: 17499-98-8

A specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A.

Kategori:
Amino Acids, Peptides, and ProteinsBacteriochlorophyllsHeterocyclic Compounds, Fused-Ring +2
Target Protein:
Bacteriochlorophyll a proteinBacteriochlorophyll a protein
Waktu Paruh-
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Genetik -
biotech

Bacteroides thetaiotaomicron is a live biotherapeutic. Developed by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.[A259892]

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BacTRL-spike DB15811
biotech

BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum engineered to deliver synthetic DNA encoding spike protein from SARS-CoV-2 contained by plasmids. The vaccine was developed by Symvivo Corporation. As of J…

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Bafetinib DB11851
small molecule | CAS: 859212-16-1

Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.

Kategori:
Enzyme InhibitorsProtein Kinase Inhibitors
Target Protein:
Tyrosine-protein kinase Lyn
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Bafilomycin A1 DB06733
small molecule | CAS: 88899-55-2

The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins are specific inhibitors of vacuolar-type H…

Kategori:
Anti-Infective AgentsAntifungal AgentsEnzyme Inhibitors +3
Target Protein:
V-type proton ATPase catalytic subunit A
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Bafilomycin B1 DB06734
small molecule | CAS: 88899-56-3

Deskripsi belum tersedia.

Kategori:
LactonesPolyketides
Target Protein:
V-type proton ATPase catalytic subunit A
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Balicatib DB12239
small molecule | CAS: 354813-19-7

Balicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +1
Target Protein:
Cathepsin K
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Baliforsen DB17852
biotech | CAS: 1698048-23-5

Deskripsi belum tersedia.

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Balixafortide DB15370
biotech | CAS: 1051366-32-5

Balixafortide is under investigation in clinical trial NCT03786094 (Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
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Baloramotide DB17986
biotech | CAS: 2207581-19-7

Deskripsi belum tersedia.

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Baloxavir DB15675
small molecule | CAS: 1985605-59-1

Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).

Kategori:
Anti-Infective AgentsAntiviral AgentsBaloxavir and prodrugs +8
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Baloxavir marboxil Approved DB13997
small molecule | CAS: 1985606-14-1

Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +25
Target Protein:
Polymerase acidic protein
Waktu ParuhThe apparent termin…
Vol. DistribusiThe volume of distr…
KlirensClearance of baloxa…
Genetik -
Balsalazide Approved DB01014
small molecule | CAS: 80573-04-2

Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenz…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +27
Target Protein:
Peroxisome proliferator-activated receptor gammaProstaglandin G/H synthase 2Prostaglandin G/H synthase 1 +1
Waktu ParuhHalf-life could not…
Vol. Distribusi-
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Balstilimab DB15676
biotech | CAS: 2148321-77-9

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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Baltaleucel-T DB19145
biotech

Deskripsi belum tersedia.

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Balugrastim DB12699
biotech | CAS: 527698-09-5

Balugrastim has been used in trials studying the treatment of Solid Tumors.

Kategori:
Adjuvants, ImmunologicAlbuminsAmino Acids, Peptides, and Proteins +14
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Bambermycins DB11377
small molecule | CAS: 11015-37-5

Bambermycins are antibiotic complexes which are retrieved from the organism, _Streptomyces bambergiensis_. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics consists primarily of moenomycins A and C.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntigens +5
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biotech

Deskripsi belum tersedia.

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Bambuterol DB01408
small molecule | CAS: 81732-65-2

Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.

Kategori:
Adrenergic AgonistsAdrenergic beta-2 Receptor AgonistsAdrenergic beta-Agonists +20
Target Protein:
Beta-2 adrenergic receptorCholinesterase
Waktu Paruh13 hours for bambut…
Vol. Distribusi-
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Bamet-UD2 DB08857
small molecule

Bamet-UD2 is a novel bile acid-platinum derivative.

Kategori:
Bile Acids and SaltsCholanesCholic Acids +3
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