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16618

Total database: 17430
Struktur (SMILES)
11654 (70.1%)
Target
8974 (54.0%)
Genomik
112 (0.7%)
Referensi
16618 (100.0%)

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Hasil Pencarian (16618)

Halaman 55 / 333
ADAM I-123 DB19213
small molecule | CAS: 305352-16-3

ADAM I-123 is under investigation in clinical trial NCT01160263 (Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls).

Waktu Paruh-
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Genetik -
Adamantane DB03627
small molecule

A tricyclo bridged hydrocarbon. [PubChem]

Kategori:
Bridged-Ring CompoundsCycloparaffins
Target Protein:
Camphor 5-monooxygenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Camphor 5-monooxygenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Camphor 5-monooxygenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Adamantanone DB02125
small molecule | CAS: 700-58-3

Deskripsi belum tersedia.

Kategori:
Bridged-Ring CompoundsCycloparaffins
Target Protein:
Camphor 5-monooxygenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Adapalene Approved DB00210
small molecule | CAS: 106685-40-9

Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with _Cutibacterium acnes_ (also known as…

Kategori:
Anti-Acne PreparationsAnti-Acne Preparations for Topical UseAnti-Inflammatory Agents +5
Target Protein:
Retinoic acid receptor betaRetinoic acid receptor gammaRetinoic acid receptor RXR-beta +6
Waktu ParuhIn one clinical stu…
Vol. Distribusi-
KlirensAdapalene is rapidl…
Genetik -
Adavosertib DB11740
small molecule | CAS: 955365-80-7

MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.

Kategori:
Enzyme InhibitorsPyrimidines
Target Protein:
Wee1-like protein kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ADC4022 DB05195
small molecule

ADC4022 is an investigational medicine for the treatment of Chronic Obstructive Pulmonary Disease (COPD) and severe asthma.

Waktu Paruh-
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Adebrelimab DB16412
biotech | CAS: 2247114-85-6

Adebrelimab is under investigation in clinical trial NCT03711305 (Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-stage (ES) Small Cell Lung Cancer (SCLC)).

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Adecatumumab DB05006
biotech | CAS: 503605-66-1

Adecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity to epithelial cell adhesion molecule (EpCAM). EpCAM (CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types,…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +14
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Adefovir DB13868
small molecule | CAS: 106941-25-7

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsAntiviral AgentsEnzyme Inhibitors +8
Target Protein:
Protein PDNA polymerase catalytic subunit
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Adefovir dipivoxil Approved DB00718
small molecule | CAS: 142340-99-6

Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir …

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +14
Target Protein:
Protein P
Waktu ParuhPlasma adefovir con…
Vol. Distribusi* 392 ± 75 mL/kg [V…
Klirens* 469 ± 99.0 mL/min…
Genetik -
Adegramotide DB17248
small molecule | CAS: 1252802-98-4

Deskripsi belum tersedia.

Waktu Paruh-
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Adelmidrol DB16083
small molecule | CAS: 1675-66-7

Adelmidrol is under investigation in clinical trial NCT01420510 (Saginil in vs. Placebo for Gynecologic Oncology Patients Affected by Vaginitis).

Kategori:
Acids, AcyclicFatty AcidsLipids
Waktu Paruh-
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Ademetionine Approved DB00118
small molecule | CAS: 29908-03-0

Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)

Kategori:
Alimentary Tract and MetabolismAmino AcidsAmino Acids and Derivatives +14
Target Protein:
Catechol O-methyltransferaseCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1Arsenite methyltransferase +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Adenine Approved DB00173
small molecule | CAS: 73-24-5

A purine base and a fundamental unit of adenine nucleotides.

Kategori:
Dietary SupplementsHeterocyclic Compounds, Fused-RingPurines +2
Target Protein:
Adenine phosphoribosyltransferaseDNAS-methyl-5'-thioadenosine phosphorylase +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Adenosine Approved DB00640
small molecule | CAS: 58-61-7

The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were not described in literature until the 1940s.[A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] thou…

Kategori:
Adenosine, antagonists & inhibitorsAgents producing tachycardiaAlkenes +32
Target Protein:
Adenosine receptor A1Adenosine receptor A2aAdenosine receptor A2b +1
Waktu ParuhThe half life of ad…
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik -
small molecule | CAS: 1053-73-2

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesHeterocyclic Compounds, Fused-RingIsomerism +5
Target Protein:
Heparan sulfate glucosamine 3-O-sulfotransferase 1Sulfotransferase 2B1Non-secretory ribonuclease +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 3768-14-7

Deskripsi belum tersedia.

Kategori:
5'-Nucleotidase, antagonists & inhibitorsAdenine NucleotidesEnzyme Inhibitors +6
Target Protein:
5'-nucleotidaseDNARibose-phosphate pyrophosphokinase +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 485-84-7

5'-Adenylic acid, monoanhydride with sulfuric acid. The initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS.

Kategori:
Adenine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4
Target Protein:
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1ATP sulfurylase (Sulfate adenylyltransferase)
Waktu Paruh-
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Genetik -
small molecule | CAS: 35094-46-3

A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.

Kategori:
Adenine NucleotidesAffinity LabelsCompounds used in a research, industrial, or household setting +8
Target Protein:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2Synapsin-1Branched-chain alpha-ketoacid dehydrogenase kinase +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 58-64-0

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4
Target Protein:
P2Y purinoceptor 6Transient receptor potential cation channel subfamily M member 4P2Y purinoceptor 12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Bis(5'-adenosyl)-triphosphatase
Waktu Paruh-
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Genetik -
Adenosine phosphate Approved DB00131
small molecule | CAS: 61-19-8

Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor ef…

Kategori:
Adenine NucleotidesDietary SupplementsHeterocyclic Compounds, Fused-Ring +6
Target Protein:
5'-AMP-activated protein kinaseAdenosine kinase5'-AMP-activated protein kinase subunit beta-1 +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAdenine Nucleotides +8
Target Protein:
Nucleoside diphosphate kinase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Eosinophil cationic proteinRibonuclease pancreaticNon-secretory ribonuclease
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nuclease P1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Vanadates
Target Protein:
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Adenosine 5'-monophosphoramidase HINT1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Serves as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin in higher plants. [PubChem]

Target Protein:
ADP-L-glycero-D-manno-heptose-6-epimerase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Diadenosine hexaphosphate hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Acetyl-coenzyme A synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Adenylate cyclase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Folylpolyglutamate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Insulin receptorFolylpolyglutamate synthaseChemotaxis protein CheA +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
NAD-dependent protein deacylase sirtuin-5, mitochondrialp-hydroxybenzoate hydroxylaseADP-ribose pyrophosphatase +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Actively Acquired ImmunityAdenovirus VaccinesLive Human Adenovirus Type 7 Vaccine +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Adenovirus/PNP DB17175
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Ribonuclease pancreatic
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 19046-78-7

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesAmino AcidsAmino Acids, Acidic +9
Target Protein:
Adenylosuccinate synthetase isozyme 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1985-21-3

Deskripsi belum tersedia.

Kategori:
Nucleic Acids, Nucleotides, and NucleosidesNucleotidesOligonucleotides +1
Target Protein:
Diphtheria toxin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ADH-1 DB05485
biotech

Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investiga…

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Genetik -
ADH-503 DB17133
small molecule | CAS: 2055362-74-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
AdimrSC-2f DB16436
biotech

The AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine manufacturer with both EU GMP and US FDA certification in Asia[L30553]. A phase I study (NCT04522089) will investigate the safety and immunogenicity of t…

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Genetik -
Adinazolam DB00546
small molecule | CAS: 37115-32-5

Adinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant properties. Adinazolam was first developed to enhance the antidepressant effects of [alprazolam]. It has never been approved by the FDA for clin…

Kategori:
Anti-Anxiety AgentsAntidepressive AgentsBenzazepines +12
Target Protein:
Translocator proteinGABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding Site
Waktu ParuhLess than 3 hours.
Vol. Distribusi-
Klirens-
Genetik -
Adiphenine Approved DB15795
small molecule | CAS: 64-95-9

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAnticholinergic AgentsPhenylacetates
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Adipiplon DB06579
small molecule | CAS: 840486-93-3

Adipiplon is an nonbenzodiazepine anxiolytic developed by Neurogen Corporation. It is known by the standardized identifier NG2-73.

Kategori:
Anti-Anxiety AgentsCentral Nervous System AgentsCentral Nervous System Depressants +5
Target Protein:
GABA(A) Receptor Benzodiazepine Binding SiteGamma-aminobutyric acid receptor subunit alpha-3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Adipose mesenchymal stem cells (AMSCs) are MSCs derived from adipose tissue, which is more accessible and less painful than stem cells extracted from most other sources. Autologous stem cells are those derived from a patient’s own cells while allogeneic stem …

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ADL 10-0101 DB05443
small molecule

ADL 10-0101 is a peripheral kappa opioid agonist analgesic product candidate. Preclinical trials of ADL 10-0101 have suggested that the compound may be effective for the treatment of inflammatory pain, itch and visceral pain. Because ADL 10-0101 does not cros…

Target Protein:
Kappa-type opioid receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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