Hasil Filter

16004

Total database: 17430
Struktur (SMILES)
12010 (75.0%)
Target
9041 (56.5%)
Genomik
112 (0.7%)
Referensi
16004 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (16004)

Halaman 53 / 321
small molecule | CAS: 143205-42-9

9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse.

Kategori:
Amino Acids, Peptides, and ProteinsCyclosporinsImmunosuppressive Agents +2
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
CREB-binding protein
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Neuraminidase
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small molecule

9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour agents N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 9-amino-DACA.

Target Protein:
DNA
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Genetik -
small molecule | CAS: 91421-43-1

Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.

Kategori:
AlkaloidsAntineoplastic AgentsCytochrome P-450 CYP3A Substrates +3
Target Protein:
DNA topoisomerase 1
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small molecule | CAS: 947-73-9

Deskripsi belum tersedia.

Target Protein:
6-deoxyerythronolide B hydroxylase
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Genetik -
small molecule

Deskripsi belum tersedia.

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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Purine nucleoside phosphorylase DeoD-type
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Heat shock protein HSP 90-alpha
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Heat shock protein HSP 90-alpha
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Heat shock protein HSP 90-alpha
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Heat shock protein HSP 90-alphaHeat shock protein HSP 90-beta
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Heat shock protein HSP 90-alpha
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Heat shock protein HSP 90-alpha
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin K
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9-Deazaguanine DB04356
small molecule | CAS: 65996-58-9

Deskripsi belum tersedia.

Kategori:
Cytochrome P-450 CYP1A2 SubstratesCytochrome P-450 SubstratesHeterocyclic Compounds, Fused-Ring +3
Target Protein:
Hypoxanthine-guanine-xanthine phosphoribosyltransferaseHypoxanthine-guanine phosphoribosyltransferase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingPurinesPurinones
Target Protein:
Purine nucleoside phosphorylasePurine nucleoside phosphorylase
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9-deazainosine DB02796
small molecule | CAS: 89458-19-5

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and NucleosidesNucleosides +3
Target Protein:
Purine nucleoside phosphorylase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Purine nucleoside phosphorylase
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Wee1-like protein kinase
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Wee1-like protein kinase
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Group IIE secretory phospholipase A2
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Genetik -
small molecule

Deskripsi belum tersedia.

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9-Methylguanine DB02489
small molecule | CAS: 5502-78-3

Deskripsi belum tersedia.

Kategori:
Cytochrome P-450 CYP1A2 SubstratesCytochrome P-450 SubstratesHeterocyclic Compounds, Fused-Ring +3
Target Protein:
Dihydroneopterin aldolase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Cholinesterase Inhibitors
Target Protein:
Cholinesterase
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99mTc-14 F7 Mab DB05867
biotech

99mTc 14F7 Mab has strong anti tumor activity against myeloma cells in vivo. Growth inhibition and prolonged survival of the myeloma tumor were obtained as evidences of anti tumor effect after treatment with 99mTc 14F7 Mab.

Target Protein:
Lactosylceramide alpha-2,3-sialyltransferase
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99mTc-glucarate DB05810
small molecule

99mTc-glucarate(GLA) is an agent for non-invasive detection of breast tumours.

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small molecule | CAS: 913556-61-3

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsOrganometallic CompoundsPeptides +1
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9CUAB30 DB12316
small molecule | CAS: 205252-57-9

9 Cuab30 has been used in trials studying the treatment and prevention of HER2/Neu Positive, HER2/Neu Negative, No Evidence of Disease, Estrogen Receptor Negative, and estrogen receptor positive, among others.

Kategori:
Fatty AcidsLipids
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9r,13r-Opda DB03007
small molecule

Deskripsi belum tersedia.

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small molecule | CAS: 1474-34-6

?-Hydroxythiofentanyl is an analgesic of the _opioid_ class. This drug is an analog of fentanyl, a potent opioid.

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small molecule | CAS: 101860-00-8

?-Methylacetylfentanyl is an analog of fentanyl with opioid analgesic properties. It was categorized under the Schedule I in the US and it was illegally sold in early 1980. ?-Methylacetylfentanyl synthesis process is very similar to ?-methylfentanyl with the …

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small molecule | CAS: 79704-88-4

?-Methylfentanyl is an analog of fentanyl with opioid analgesic properties.

Kategori:
Designer DrugsPiperidinesStreet Drugs
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small molecule | CAS: 79146-56-8

?-Methylfentanyl is an analgesic of the _opioid_ class. It is an analog of the potent opioid, fentanyl.

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?A?–Gas6 DB17069
biotech

?A?–Gas6 is a chimeric fusion protein being investigated in preclinical studies as an immunotherapeutic agent for Alzheimer's disease (AD). It is made of a single chain variable fragment (scFv) of an Amyloid ? (A?)-targeting monoclonal antibody fused with a t…

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A-16L DB18270
biotech | CAS: 410527-75-2

Deskripsi belum tersedia.

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A-620223 DB07330
small molecule | CAS: 272769-49-0

Deskripsi belum tersedia.

Target Protein:
Poly [ADP-ribose] polymerase 1
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A-674563 DB08568
small molecule | CAS: 552325-73-2

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingPyrazoles
Target Protein:
RAC-alpha serine/threonine-protein kinasecAMP-dependent protein kinase catalytic subunit alphacAMP-dependent protein kinase inhibitor alpha
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A-98881 DB02804
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
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biotech | CAS: 1470038-56-2

A-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides).

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A166 DB17413
biotech

A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.

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AAG-1 DB17199
small molecule | CAS: 1204408-18-3

Deskripsi belum tersedia.

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AAV-AIPL DB17857
biotech

AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in _AIPL1_ gene.

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AAV-AQP1 DB17417
biotech

Deskripsi belum tersedia.

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AAV-CNGB3 DB18344
biotech

AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.

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AAV-dXIAP DB17880
biotech

AAV-dXIAP is a recombinant adeno-associated virus-encoded gene for X-linked mammalian inhibitor of apoptosis protein (XIAP) developed by Neurologix.

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AAV-RPE65 DB18343
biotech

AAV-RPE65 is an adenovirus associated viral vector serotype 5 containing the human RPE65 gene

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AAV1-FS344 DB17855
biotech

AAV1-FS344 is an investigational gene therapy developed by Milo Biotechnology to deliver follistatin, a potent myostatin inhibitor. It is being investigated for the treatment of Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and inclusion body myosit…

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biotech

Deskripsi belum tersedia.

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AAV9/MFSD8 DB18616
biotech

AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8.…

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