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11778

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8554 (72.6%)
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6383 (54.2%)
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96 (0.8%)
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11778 (100.0%)

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Halaman 52 / 236
Azvudine DB16407
small molecule | CAS: 1011529-10-4

Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)).

Kategori:
DeoxyribonucleosidesExperimental Unapproved Treatments for COVID-19Nitrogen Compounds +4
Target Protein:
Broad substrate specificity ATP-binding cassette transporter ABCG2ATP-binding cassette sub-family C member 2ATP-dependent translocase ABCB1
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AZX-100 DB06323
biotech | CAS: 1217194-46-1

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsHeat-Shock ProteinsMolecular Chaperones +1
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small molecule | CAS: 69984-73-2

Deskripsi belum tersedia.

Target Protein:
Pancreatic triacylglycerol lipaseCytochrome c oxidase subunit 1Cytochrome c oxidase subunit 2 +11
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B27PD DB16289
biotech | CAS: 160387-12-2

B27PD is under investigation in clinical trial NCT01195948 (Optiquel® as Corticosteroid-sparing Therapy for Chronic Noninfectious Uveitis).

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biotech

Deskripsi belum tersedia.

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BA-2664 DB01479
small molecule | CAS: 641-82-7

Deskripsi belum tersedia.

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Bacampicillin Approved DB01602
small molecule | CAS: 50972-17-3

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbi…

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Target Protein:
Penicillin-binding protein
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Baccharis halimifolia pollen Approved DB10757
biotech

Baccharis halimifolia pollen is the pollen of the Baccharis halimifolia plant. Baccharis halimifolia pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Deskripsi belum tersedia.

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biotech

Bacillus Calmette-Guerin (BCG) substrain Russian BCG-I is a live BCG vaccine administered directly into the bladder for the adjuvant treatment of papillary urothelial cell carcinoma of the bladder. Live BCG vaccines administered intravesically have been a gol…

Kategori:
Antineoplastic AgentsLive vaccinesVaccines
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biotech

Bacillus calmette-guerin substrain tokyo 172-1 live antigen is under investigation in clinical trial NCT03091660 (S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer).

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Bacillus cereus DB19245
biotech | CAS: 68038-62-0

Deskripsi belum tersedia.

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biotech

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biotech | CAS: 68038-66-4

Deskripsi belum tersedia.

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biotech | CAS: 68038-70-0

Deskripsi belum tersedia.

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Bacitracin Approved DB00626
small molecule | CAS: 1405-87-4

Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A.[A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named …

Kategori:
Acids, CarbocyclicAmino Acids, Peptides, and ProteinsAnti-Bacterial Agents +19
Target Protein:
C55-isoprenyl pyrophosphateInsulin-degrading enzymeAlpha-2-macroglobulin
Waktu ParuhData regarding the …
Vol. DistribusiData regarding the …
KlirensData regarding the …
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Baclofen Approved DB00181
small molecule | CAS: 1134-47-0

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patie…

Kategori:
Agents Causing Muscle ToxicityAmino AcidsAmino Acids, Peptides, and Proteins +15
Target Protein:
Gamma-aminobutyric acid type B receptor subunit 2C-X-C chemokine receptor type 4Gamma-aminobutyric acid type B receptor subunit 1
Waktu ParuhThe half-life is 2-…
Vol. DistribusiThe volume of distr…
KlirensThe systemic cleara…
Genetik -
small molecule | CAS: 17499-98-8

A specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A.

Kategori:
Amino Acids, Peptides, and ProteinsBacteriochlorophyllsHeterocyclic Compounds, Fused-Ring +2
Target Protein:
Bacteriochlorophyll a proteinBacteriochlorophyll a protein
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biotech

Bacteroides thetaiotaomicron is a live biotherapeutic. Developed by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.[A259892]

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Bafilomycin A1 DB06733
small molecule | CAS: 88899-55-2

The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins are specific inhibitors of vacuolar-type H…

Kategori:
Anti-Infective AgentsAntifungal AgentsEnzyme Inhibitors +3
Target Protein:
V-type proton ATPase catalytic subunit A
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Bafilomycin B1 DB06734
small molecule | CAS: 88899-56-3

Deskripsi belum tersedia.

Kategori:
LactonesPolyketides
Target Protein:
V-type proton ATPase catalytic subunit A
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Baicalein DB16101
small molecule | CAS: 491-67-8

Baicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ?A Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of Improve Other Aspects of Healthy …

Kategori:
AntioxidantsBenzopyransBiological Factors +11
Target Protein:
Lactoylglutathione lyaseTumor necrosis factorXanthine dehydrogenase/oxidase +4
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Bakuchiol DB16102
small molecule | CAS: 10309-37-2

Bakuchiol is under investigation in clinical trial NCT03112863 (Comparison of the Cosmetic Effects of Bakuchiol and Retinol).

Kategori:
Benzene Derivatives
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BAL200 DB17793
biotech

Deskripsi belum tersedia.

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Balaglitazone DB12781
small molecule | CAS: 199113-98-9

Balaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2.

Kategori:
Blood Glucose Lowering AgentsCytochrome P-450 CYP2C8 InhibitorsCytochrome P-450 CYP2C8 Inhibitors (strength unknown) +9
Target Protein:
Peroxisome proliferator-activated receptor gamma
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Balapiravir DB12283
small molecule | CAS: 690270-29-2

Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic.

Kategori:
CarbohydratesGlycosidesNucleic Acids, Nucleotides, and Nucleosides
Target Protein:
Genome polyprotein
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Balhimycin DB04111
small molecule | CAS: 140932-79-2

Balhimycin is a novel glycopeptide antibiotic.

Kategori:
Amino Acids, Peptides, and ProteinsCarbohydratesGlycoconjugates +2
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Balicatib DB12239
small molecule | CAS: 354813-19-7

Balicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +1
Target Protein:
Cathepsin K
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Baliforsen DB17852
biotech | CAS: 1698048-23-5

Deskripsi belum tersedia.

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Balipodect DB14774
small molecule | CAS: 1238697-26-1

Balipodect is under investigation in clinical trial NCT01892189 (Effects of TAK-063 on Preventing Ketamine-Induced Brain Activity Changes as Well as Psychotic-Like Symptoms in Healthy Male Adults).

Target Protein:
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
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Balixafortide DB15370
biotech | CAS: 1051366-32-5

Balixafortide is under investigation in clinical trial NCT03786094 (Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
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Baloramotide DB17986
biotech | CAS: 2207581-19-7

Deskripsi belum tersedia.

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Balovaptan DB14823
small molecule | CAS: 1228088-30-9

Balovaptan is under investigation in clinical trial NCT01793441 (A Study of RG7314 to Investigate Efficacy and Safety in Individuals With Autism Spectrum Disorders (ASD)).

Kategori:
Antidiuretic Hormone Receptor AntagonistsBenzazepinesHeterocyclic Compounds, Fused-Ring +1
Target Protein:
Vasopressin V1a receptor
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Baloxavir DB15675
small molecule | CAS: 1985605-59-1

Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).

Kategori:
Anti-Infective AgentsAntiviral AgentsBaloxavir and prodrugs +8
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Baloxavir marboxil Approved DB13997
small molecule | CAS: 1985606-14-1

Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +25
Target Protein:
Polymerase acidic protein
Waktu ParuhThe apparent termin…
Vol. DistribusiThe volume of distr…
KlirensClearance of baloxa…
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Balsalazide Approved DB01014
small molecule | CAS: 80573-04-2

Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenz…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +27
Target Protein:
Peroxisome proliferator-activated receptor gammaProstaglandin G/H synthase 2Prostaglandin G/H synthase 1 +1
Waktu ParuhHalf-life could not…
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Balsam of Peru DB11482
small molecule | CAS: 8007-00-9

Balsam of Peru is a resin that comes from the tree Myroxylon balsamum pereirae. It is constituted by a mixture of substances from which the major components are benzyl cinnamate and [DB00676]. Balsam of Peru has also presented several allergens such as cinnam…

Kategori:
Biological ProductsBiopolymersCell-mediated Immunity +8
Waktu ParuhThis pharmacokineti…
Vol. DistribusiThis pharmacokineti…
KlirensThis pharmacokineti…
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Balstilimab DB15676
biotech | CAS: 2148321-77-9

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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Balugrastim DB12699
biotech | CAS: 527698-09-5

Balugrastim has been used in trials studying the treatment of Solid Tumors.

Kategori:
Adjuvants, ImmunologicAlbuminsAmino Acids, Peptides, and Proteins +14
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Bambermycins DB11377
small molecule | CAS: 11015-37-5

Bambermycins are antibiotic complexes which are retrieved from the organism, _Streptomyces bambergiensis_. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics consists primarily of moenomycins A and C.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntigens +5
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Bambuterol DB01408
small molecule | CAS: 81732-65-2

Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.

Kategori:
Adrenergic AgonistsAdrenergic beta-2 Receptor AgonistsAdrenergic beta-Agonists +20
Target Protein:
Beta-2 adrenergic receptorCholinesterase
Waktu Paruh13 hours for bambut…
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Bamet-UD2 DB08857
small molecule

Bamet-UD2 is a novel bile acid-platinum derivative.

Kategori:
Bile Acids and SaltsCholanesCholic Acids +3
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Bamethan DB13206
small molecule | CAS: 3703-79-5

Deskripsi belum tersedia.

Kategori:
2-Amino-1-Phenylethanol DerivativesAlcoholsAmines +5
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Baminercept DB06576
biotech | CAS: 909110-25-4

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsProteinsRecombinant Proteins
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Bamipine DB13489
small molecule | CAS: 4945-47-5

Deskripsi belum tersedia.

Kategori:
Antihistamines for Systemic UseAntihistamines for Topical UseAntipruritics, Incl. Antihistamines, Anesthetics, Etc. +4
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Bamlanivimab Approved DB15718
biotech | CAS: 2423943-37-5

Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of the first blood samples in the United States from a patient who recovered from COVID-19.[A224039, L15311, L15316] Bamlanivimab is a neutralizing Ig…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntibodies +10
Target Protein:
Spike glycoprotein
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Bamocaftor DB15177
small molecule | CAS: 2204245-48-5

Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis).

Kategori:
Chloride Channel AgonistsMembrane Transport Modulators
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Bamosiran DB12256
biotech | CAS: 1337968-84-9

Bamosiran has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, and Open Angle Glaucoma.

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Banoxantrone DB04975
small molecule | CAS: 136470-65-0

Banoxantrone is a highly selective bioreductive drug that is activated in, and is preferentially toxic to, hypoxic cells in tumours. It has been shown to work synergistically with fractionated radiation to significantly delay growth of tumours compared to adm…

Kategori:
AnthracenesAntineoplastic AgentsCytochrome P-450 CYP2B6 Substrates +4
Target Protein:
DNA topoisomerase 2-betaDNA topoisomerase 2-alpha
Waktu Paruh0.64 to 0.83 hours
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Bapineuzumab DB11715
biotech | CAS: 648895-38-9

Bapineuzumab has been investigated for the treatment of Alzheimer's Disease.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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