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8,9,10-Trihydroxy-7-hydroxymethyl-2-thioxo-6-oxa-1,3-diaza-spiro[4.5]decan-4-one DB02964

small molecule | CAS: 227458-60-8

Deskripsi belum tersedia.

Target Protein:

Glycogen phosphorylase, muscle form

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8,9,10-trihydroxy-7-hydroxymethyl-3-methyl-6-oxa-1,3-diaza-spiro[4.5]decane-2,4-dione DB03479

small molecule

Deskripsi belum tersedia.

Target Protein:

Glycogen phosphorylase, muscle form

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8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine DB04273

small molecule

Deskripsi belum tersedia.

Target Protein:

Phenylethanolamine N-methyltransferase

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8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine DB03137

small molecule

Deskripsi belum tersedia.

Target Protein:

Heat shock protein HSP 90-alpha

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8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine DB03093

small molecule

Deskripsi belum tersedia.

Target Protein:

Heat shock protein HSP 90-alpha

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8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine DB02550

small molecule

Deskripsi belum tersedia.

Target Protein:

Heat shock protein HSP 90-alpha

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8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine DB04505

small molecule

Deskripsi belum tersedia.

Target Protein:

Heat shock protein HSP 90-alpha

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8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM DB08096

small molecule

Deskripsi belum tersedia.

Target Protein:

Mitogen-activated protein kinase 14

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8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE DB07877

small molecule

Deskripsi belum tersedia.

Target Protein:

Heat shock protein HSP 90-betaHeat shock protein HSP 90-alpha

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8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide DB04059

small molecule

Deskripsi belum tersedia.

Target Protein:

Urokinase-type plasminogen activator

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8-Aminotheophylline DB01778

small molecule | CAS: 19410-53-8

Deskripsi belum tersedia.

Target Protein:

Dihydroneopterin aldolase

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8-anilinonaphthalene-1-sulfonic acid DB04474

small molecule | CAS: 82-76-8

Deskripsi belum tersedia.

Kategori:

AminesAniline CompoundsArylsulfonates +12

Target Protein:

Fatty acid-binding protein, liverProtein S100-A7UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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8-azaguanine DB01667

small molecule | CAS: 134-58-7

8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.

Kategori:

AntimetabolitesAntineoplastic AgentsAza Compounds +8

Target Protein:

Purine nucleoside phosphorylase

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8-azaxanthine DB01875

small molecule | CAS: 1468-26-4

Deskripsi belum tersedia.

Kategori:

AlkaloidsHeterocyclic Compounds, Fused-RingPurines +1

Target Protein:

Uric acid degradation bifunctional protein

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8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine DB04254

small molecule

Deskripsi belum tersedia.

Target Protein:

Heat shock protein HSP 90-alpha

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8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- DB08436

small molecule

Deskripsi belum tersedia.

Target Protein:

Heat shock protein HSP 90-alpha

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8-Benzyl-2-Hydroperoxy-2-(4-Hydroxy-Benzyl)-6-(4-Hydroxy-Phenyl)-2h-Imidazo[1,2-a]Pyrazin-3-One DB02241

small molecule

Deskripsi belum tersedia.

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8-Benzyl-2-Hydroxy-2-(4-Hydroxy-Benzyl)-6-(4-Hydroxy-Phenyl)-2h-Imidazo[1,2-a]Pyrazin-3-One DB02194

small molecule

Deskripsi belum tersedia.

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8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide DB08365

small molecule

Deskripsi belum tersedia.

Target Protein:

Wee1-like protein kinase

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8-Bromo-Adenosine-5'-Monophosphate DB03349

small molecule

Deskripsi belum tersedia.

Target Protein:

3',5'-cyclic-AMP phosphodiesterase 4BAdenosine 5'-monophosphoramidase HINT1

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8-Bromoadenosine-5'-Diphosphate DB04554

small molecule

Deskripsi belum tersedia.

Target Protein:

S-adenosylmethionine synthase

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8-Chloroadenosine DB16075

small molecule | CAS: 34408-14-5

8-Chloroadenosine is under investigation in clinical trial NCT02509546 (8-chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia).

Kategori:

Heterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and NucleosidesNucleosides +3

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8-chlorotheophylline DB14132

small molecule | CAS: 85-18-7

8-Chlorotheophylline is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine. Its main use is in combination with [Diphenhydramine] as the antiemetic drug [Dimenhydrinate]. The stimulant properties of 8-chlorotheophy…

Kategori:

AlkaloidsCytochrome P-450 CYP1A2 SubstratesCytochrome P-450 Substrates +4

Target Protein:

Adenosine receptor A2a

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8-demethyl-8-dimethylamino-flavin-adenine-dinucleotide DB03482

small molecule

Deskripsi belum tersedia.

Target Protein:

p-hydroxybenzoate hydroxylase

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8-epi-Cyanocobalamin DB14092

small molecule | CAS: 41325-63-7

Deskripsi belum tersedia.

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8-hydroxy-2'-deoxyguanosine DB02502

small molecule | CAS: 88847-89-6

Deskripsi belum tersedia.

Kategori:

Adjuvants, ImmunologicDeoxyguanosineDeoxyribonucleosides +7

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8-Hydroxy-2-oxa-bicyclo[3.3.1]non-6-ene-3,5-dicarboxylic acid DB08648

small molecule

Deskripsi belum tersedia.

Target Protein:

P-proteinChorismate mutase AroHSecreted chorismate mutase

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8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic Acid DB02566

small molecule

Deskripsi belum tersedia.

Target Protein:

Thiostrepton50S ribosomal protein L11

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8-iodo-guanine DB02985

small molecule

Deskripsi belum tersedia.

Target Protein:

Purine nucleoside phosphorylasePurine nucleoside phosphorylase

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8-Methyl-9-Oxoguanine DB02993

small molecule

Deskripsi belum tersedia.

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8-oxo-dGMP DB02023

small molecule | CAS: 127027-50-3

Deskripsi belum tersedia.

Kategori:

Guanine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4

Target Protein:

8-oxo-dGTP diphosphatase

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9(S)-HODE DB07302

small molecule | CAS: 73543-67-6

Deskripsi belum tersedia.

Target Protein:

Peroxisome proliferator-activated receptor gamma

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9,10-Deepithio-9,10-Didehydroacanthifolicin DB02169

small molecule | CAS: 78111-17-8

A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41)

Target Protein:

Dual specificity protein phosphatase 1Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

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9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE DB07553

small molecule

Deskripsi belum tersedia.

Target Protein:

Histone deacetylase 8Histone deacetylase 4Histone deacetylase 1 +4

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9-(2-carboxyethyl)-10-methylanthracene endoperoxide DB08332

small molecule

Deskripsi belum tersedia.

Target Protein:

Immunoglobulin heavy constant gamma 1

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9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine DB03735

small molecule

Deskripsi belum tersedia.

Target Protein:

Purine nucleoside phosphorylase DeoD-type

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9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE DB07940

small molecule

Deskripsi belum tersedia.

Kategori:

Cholinesterase Inhibitors

Target Protein:

Cholinesterase

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9-(4-hydroxybutyl)-N2-phenylguanine DB02495

small molecule

9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine is known to target thymidine kinase.

Target Protein:

Thymidine kinase, cytosolicThymidine kinase

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9-(4-Hydroxyphenyl)-2,7-Phenanthroline DB03623

small molecule

Deskripsi belum tersedia.

Target Protein:

Mitogen-activated protein kinase 10

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9-(5,5-Difluoro-5-Phosphonopentyl)Guanine DB04260

small molecule

Deskripsi belum tersedia.

Target Protein:

Purine nucleoside phosphorylase

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9-(6-deoxy-alpha-L-talofuranosyl)-6-methylpurine DB02934

small molecule

Deskripsi belum tersedia.

Target Protein:

Purine nucleoside phosphorylase DeoD-type

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9-(6-deoxy-beta-D-allofuranosyl)-6-methylpurine DB03952

small molecule

Deskripsi belum tersedia.

Target Protein:

Purine nucleoside phosphorylase DeoD-type

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9-(N-methyl-L-isoleucine)-cyclosporin A DB13068

small molecule | CAS: 143205-42-9

9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse.

Kategori:

Amino Acids, Peptides, and ProteinsCyclosporinsImmunosuppressive Agents +2

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9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE DB08655

small molecule

Deskripsi belum tersedia.

Target Protein:

CREB-binding protein

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9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid DB04227

small molecule

Deskripsi belum tersedia.

Target Protein:

Neuraminidase

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9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide DB02842

small molecule

9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour agents N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 9-amino-DACA.

Target Protein:

DNA

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9-aminocamptothecin DB12515

small molecule | CAS: 91421-43-1

Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.

Kategori:

AlkaloidsAntineoplastic AgentsCytochrome P-450 CYP3A Substrates +3

Target Protein:

DNA topoisomerase 1

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9-Aminophenanthrene DB03369

small molecule | CAS: 947-73-9

Deskripsi belum tersedia.

Target Protein:

6-deoxyerythronolide B hydroxylase

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9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid DB07283

small molecule

Deskripsi belum tersedia.

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9-Beta-D-Xylofuranosyl-Adenine DB03528

small molecule

Deskripsi belum tersedia.

Target Protein:

Purine nucleoside phosphorylase DeoD-type

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