Digital Pharmacy - Dashboard Peneliti

Alnus glutinosa DB15904

biotech

Deskripsi belum tersedia.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Alnus incana subsp. rugosa pollen Approved DB10453

biotech

Alnus incana subsp. rugosa pollen is the pollen of the Alnus incana subsp. rugosa plant. Alnus incana subsp. rugosa pollen is mainly used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Alnus serrulata pollen Approved DB15509

biotech

Alnus serrulata pollen allergenic extract is used in allergenic testing.

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Alobresib DB14970

small molecule | CAS: 1637771-14-2

Alobresib is under investigation in clinical trial NCT02607228 (Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer).

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Aloe ferox leaf Approved DB14257

biotech

Aloe ferox leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Aloe vera flower Approved DB14254

biotech

Aloe vera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Aloe vera leaf DB13906

biotech | CAS: 8001-97-6

Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or _Aloe barbadensis miller_, is the most common species of Aloe that is cultivated for agricultural and medica…

Target Protein:

Free radicals

Waktu ParuhNo pharmacokinetic …

Vol. DistribusiNo pharmacokinetic …

KlirensNo pharmacokinetic …

Genetik -

Alogabat DB18708

small molecule | CAS: 2230009-48-8

Deskripsi belum tersedia.

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Alogliptin Approved DB06203

small molecule | CAS: 850649-61-5

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conve…

Kategori:

Agents causing angioedemaAlimentary Tract and MetabolismBlood Glucose Lowering Agents +15

Target Protein:

Dipeptidyl peptidase 4

Waktu ParuhTerminal half-life …

Vol. DistribusiFollowing a single,…

KlirensRenal clearance = 9…

Genetik -

Aloglutamol DB13650

small molecule | CAS: 13755-41-4

Aloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro.

Kategori:

AlcoholsAlimentary Tract and MetabolismAlkalies +13

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Alomfilimab DB16681

biotech | CAS: 2378692-24-9

Alomfilimab is under investigation in clinical trial NCT03829501 (Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer).

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Alosetron Approved DB00969

small molecule | CAS: 122852-42-0

Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) pro…

Kategori:

Alimentary Tract and MetabolismAntidepressive AgentsAntiemetic Serotonin 5-HT3 Receptor Antagonists +23

Target Protein:

5-hydroxytryptamine receptor 3A

Waktu Paruh1.5 hours

Vol. Distribusi* 65 to 95 L

Klirens* 600 mL/min

Genetik -

Alovudine DB06198

small molecule | CAS: 25526-93-6

Deskripsi belum tersedia.

Kategori:

Anti-Infective AgentsAntiviral AgentsDeoxyribonucleosides +3

Target Protein:

Gag-Pol polyproteinReverse transcriptase/RNaseH

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Aloxiprin DB13509

small molecule | CAS: 9014-67-9

Deskripsi belum tersedia.

Kategori:

AnalgesicsBenzene DerivativesBlood and Blood Forming Organs +6

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Aloxistatin DB18145

small molecule | CAS: 88321-09-9

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, Branched-ChainAmino Acids, Essential +6

Target Protein:

Calpain-2 catalytic subunitCathepsin G

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Alpelisib Approved DB12015

small molecule | CAS: 1217486-61-7

Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110? [A179203], which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological proce…

Kategori:

Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Inhibitors +32

Target Protein:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Waktu ParuhThe mean half life …

Vol. DistribusiThe apparent volume…

KlirensThe mean apparent o…

Genetik -

alpha,alpha-Dibromo-D-camphor DB15659

small molecule | CAS: 514-12-5

Deskripsi belum tersedia.

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha,beta-Dehydroaminobutyric acid DB03720

small molecule | CAS: 71018-10-5

Deskripsi belum tersedia.

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha,beta-Methyleneadenosine 5'-triphosphate DB02596

small molecule | CAS: 7292-42-4

Deskripsi belum tersedia.

Kategori:

Adenine NucleotidesAntineoplastic AgentsHeterocyclic Compounds, Fused-Ring +5

Target Protein:

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasePantothenate synthetaseNH(3)-dependent NAD(+) synthetase +5

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE DB07332

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyproteinGag-Pol polyprotein

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Alpha-1-proteinase inhibitor Approved DB00058

biotech | CAS: 9041-92-3

Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.

Kategori:

Acute-Phase ProteinsAlpha-GlobulinsAmino Acids, Peptides, and Proteins +21

Target Protein:

Neutrophil elastase

Waktu Paruh-

Vol. Distribusi* 5632 ± 2006 mL [A…

Klirens* 940 +/- 275 mL/da…

Genetik -

Alpha-Aminobutyric Acid DB04454

small molecule

Deskripsi belum tersedia.

Kategori:

Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1

Target Protein:

Glycine amidinotransferase, mitochondrialGag-Pol polyproteinPro-epidermal growth factor +1

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Amyl cinnamaldehyde Approved DB14175

small molecule | CAS: 122-40-7

alpha-Amyl cinnamaldehyde has a jasmine-like odor and is a widely used synthetic fragrance & suspected allergen. It is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleasePerfume +1

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Alpha-Benzyl-Aminobenzyl-Phosphonic Acid DB03577

small molecule

Deskripsi belum tersedia.

Target Protein:

Prostatic acid phosphatase

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Carotene DB15909

small molecule | CAS: 7488-99-5

Deskripsi belum tersedia.

Kategori:

AlkenesBiological FactorsCyclohexanes +6

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Conotoxin VC 1.1 DB05724

small molecule | CAS: 467428-30-4

Deskripsi belum tersedia.

Kategori:

Biological FactorsComplex MixturesMarine Toxins +3

Target Protein:

Neuronal acetylcholine receptor subunit alpha-10

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-D-Fucopyranose DB03485

small molecule | CAS: 6189-71-5

Deskripsi belum tersedia.

Target Protein:

LactotransferrinL-arabinose-binding periplasmic protein

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Alpha-D-Galactose-1-Phosphate DB02317

small molecule | CAS: 2255-14-3

Deskripsi belum tersedia.

Target Protein:

Beta-phosphoglucomutase

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-D-galacturonic acid DB03511

small molecule | CAS: 6294-16-2

The ?-anomer of D-galacturonic acid.

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-D-glucopyranosyl-2-carboxylic acid amide DB02720

small molecule | CAS: 58825-13-1

Deskripsi belum tersedia.

Target Protein:

Glycogen phosphorylase, muscle form

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Alpha-D-Glucose 1,6-Bisphosphate DB02835

small molecule | CAS: 10139-18-1

Deskripsi belum tersedia.

Target Protein:

Beta-phosphoglucomutasePhosphoglucomutase-1

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-D-glucose 6-phosphate DB02007

small molecule | CAS: 15209-11-7

Deskripsi belum tersedia.

Target Protein:

Aldo-keto reductase family 1 member B1Glycogen phosphorylase, muscle formGlutamine--fructose-6-phosphate aminotransferase [isomerizing] +6

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-D-glucose-1-phosphate DB02843

small molecule | CAS: 59-56-3

Deskripsi belum tersedia.

Kategori:

CarbohydratesHexosephosphatesSugar Phosphates

Target Protein:

Glycogen phosphorylase, muscle formPhosphomannomutase/phosphoglucomutaseMaltodextrin phosphorylase +2

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Alpha-D-mannose 1-phosphate DB17678

small molecule | CAS: 15978-07-1

Deskripsi belum tersedia.

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-D-quinovopyranose DB03773

small molecule | CAS: 7658-08-4

The pyranose form of D-quinovose with an ?-configuration at the anomeric position .

Kategori:

CarbohydratesDeoxy Sugars

Target Protein:

Pancreatic alpha-amylaseCyclomaltodextrin glucanotransferaseAlpha-amylase +2

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Hydroxy glycineamide DB06568

small molecule

Alpha-hydroxy glycineamide (?HGA) is the active antiviral metabolite of tri-peptide glycyl-prolyl-glycine-amide (GPG-NH2). ?HGA inhibits the replication of HIV-1 in vitro by interfering with the capsid formation. It also has an effect on viral gp160 envelope …

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID DB07895

small molecule

Deskripsi belum tersedia.

Kategori:

AlcoholsFatty AlcoholsLipids +3

Target Protein:

Protein farnesyltransferase subunit betaProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Hydroxylinoleic acid DB16027

small molecule | CAS: 57818-44-7

alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study).

Kategori:

Fatty AcidsFatty Acids, EssentialFatty Acids, Omega-6 +2

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Keto-beta-methylvaleric acid DB15831

small molecule | CAS: 1460-34-0

Deskripsi belum tersedia.

Kategori:

Pentanoic Acids

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Keto-isoleucine DB15833

small molecule | CAS: 24809-08-3

Deskripsi belum tersedia.

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Ketoisovalerate DB04074

small molecule | CAS: 759-05-7

Deskripsi belum tersedia.

Kategori:

Pentanoic AcidsTerpenes

Target Protein:

Branched-chain-amino-acid aminotransferase, mitochondrial3-methyl-2-oxobutanoate hydroxymethyltransferaseDeacetoxycephalosporin C synthase +1

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-L-iduronic acid DB02945

small molecule | CAS: 71031-08-8

Deskripsi belum tersedia.

Target Protein:

Chondroitinase-AC

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-L-methyl-fucose DB03879

small molecule | CAS: 14687-15-1

Deskripsi belum tersedia.

Target Protein:

Mannose-binding protein CChondroitinase-AC

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Lactalbumin DB15182

biotech | CAS: 9051-29-0

alpha-Lactalbumin is under investigation in clinical trial NCT02082418 (Effects of Alpha-lactalbumin Intake on Metabolic and Cognitive Functions in Elderly).

Kategori:

AlbuminsAmino Acids, Peptides, and ProteinsAnimal Proteins, Dietary +7

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Linolenic acid Approved DB00132

small molecule | CAS: 463-40-1

Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.

Kategori:

Dietary FatsDietary Fats, UnsaturatedDietary Supplements +8

Target Protein:

Free fatty acid receptor 1Prostaglandin G/H synthase 2Acyl-CoA (8-3)-desaturase +10

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acid DB07668

small molecule | CAS: 125769-41-7

Deskripsi belum tersedia.

Kategori:

Acids, Carbocyclic

Target Protein:

Chymotrypsinogen B

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Methylleucine DB04063

small molecule | CAS: 105743-53-1

Deskripsi belum tersedia.

Target Protein:

Branched-chain-amino-acid aminotransferase

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-N-Acetyl-D-galactosamine DB03567

small molecule | CAS: 14215-68-0

The N-acetyl derivative of galactosamine. [PubChem]

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Naphthoflavone DB07453

small molecule | CAS: 604-59-1

Deskripsi belum tersedia.

Kategori:

BenzopyransChromonesFlavonoids +2

Target Protein:

DNA-dependent protein kinase catalytic subunitAromataseCytochrome P450 1A2

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

alpha-Pinene DB15573

small molecule | CAS: 80-56-8

Deskripsi belum tersedia.

Kategori:

Bridged-Ring CompoundsMonoterpenesTerpenes

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

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