Hasil Filter

15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (15718)

Halaman 43 / 315
Acarbose Approved DB00284
small molecule | CAS: 56180-94-0

Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal…

Kategori:
Alimentary Tract and MetabolismBlood Glucose Lowering AgentsCarbohydrates +9
Target Protein:
Maltase-glucoamylaseSucrase-isomaltase, intestinalPancreatic alpha-amylase +1
Waktu ParuhIn healthy voluntee…
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Maltogenic alpha-amylasePancreatic alpha-amylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acasunlimab DB18932
biotech | CAS: 2253937-12-9

Acasunlimab is under investigation in clinical trial NCT06046274 (GEN1046 in Combination With Anticancer Agents for the Treatment of Advanced Endometrial Cancer).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acazicolcept DB18410
biotech | CAS: 2270247-50-0

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsImmunologic FactorsImmunosuppressive Agents +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ACE393 DB05071
small molecule

ACE393 is an injectable vaccine designed to combat the bacterium Campylobacter jejuni, one of the greatest causes of bacterial diarrhoeal infections in the developed world.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acebilustat DB15385
small molecule | CAS: 943764-99-6

Acebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety and Tolerability of CTX-4430).

Kategori:
Acids, CarbocyclicAza CompoundsBenzene Derivatives
Target Protein:
Leukotriene A-4 hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acebutolol Approved DB01193
small molecule | CAS: 37517-30-9

A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-1 Receptor Antagonists +29
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptor
Waktu ParuhThe plasma eliminat…
Vol. Distribusi-
Klirens-
Genetik -
Acecainide DB17602
small molecule | CAS: 32795-44-1

Acecainide is an investigational anti-arrhythmia drug.

Kategori:
Acids, CarbocyclicAminobenzoatesAntiarrhythmic agents +5
Target Protein:
Sodium channel protein type 5 subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Aceclidine Approved DB13262
small molecule | CAS: 827-61-2

Aceclidine has been marketed in Europe but has not been used clinically in the United States. It is used in the treatment of open-angle glaucoma and is a parasympathomimetic agent.

Kategori:
Antiglaucoma Preparations and MioticsAutonomic AgentsMiotics +4
Target Protein:
Muscarinic acetylcholine receptor M5Muscarinic acetylcholine receptor M4Muscarinic acetylcholine receptor M3 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Aceclofenac Approved DB06736
small molecule | CAS: 89796-99-6

Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action …

Kategori:
Acetic Acid Derivatives and Related SubstancesAcids, CarbocyclicAgents causing hyperkalemia +20
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
Waktu ParuhThe mean plasma eli…
Vol. DistribusiThe volume of distr…
KlirensThe mean clearance …
Genetik -
Acedoben DB04500
small molecule | CAS: 556-08-1

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAminobenzoatesBenzene Derivatives +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acefylline DB13573
small molecule | CAS: 652-37-9

Deskripsi belum tersedia.

Kategori:
AlkaloidsCytochrome P-450 CYP1A2 SubstratesCytochrome P-450 Substrates +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Aceglutamide DB04167
small molecule | CAS: 2490-97-3

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +2
Target Protein:
o-succinylbenzoate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acemannan DB19224
small molecule | CAS: 110042-95-0

Acemannan is under investigation in clinical trial NCT03250923 (Celagace™ Orarinse Solution for Treatment of Candidiasis).

Kategori:
Adjuvants, ImmunologicAnti-Infective AgentsAntineoplastic Agents +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acemetacin Approved DB13783
small molecule | CAS: 53164-05-9

Acemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin.[A31352] In clinical trials, aceme…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +16
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu ParuhThe elimination hal…
Vol. DistribusiThe apparent volume…
KlirensIntravenous adminis…
Genetik -
small molecule | CAS: 131-48-6

Aceneuramic acid has been used in trials studying the treatment of Distal Myopathy, Nonaka Type, Hereditary Inclusion Body Myopathy, and Distal Myopathy With Rimmed Vacuoles.

Kategori:
Musculo-Skeletal System
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acenocoumarol Approved DB01418
small molecule | CAS: 152-72-7

Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagul…

Kategori:
4-HydroxycoumarinsAnticoagulantsBenzopyrans +19
Target Protein:
Vitamin K epoxide reductase complex subunit 1
Gen Terkait:
CYP2C9 CYP2C9 CYP2C9 +2
Waktu Paruh8 to 11 hours.
Vol. DistribusiThe volume of distr…
Klirens-
Genetik 5 Varian
Acepromazine DB01614
small molecule | CAS: 61-00-7

Acepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.

Kategori:
Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +24
Target Protein:
D(2) dopamine receptorD(1A) dopamine receptor5-hydroxytryptamine receptor 2A +3
Waktu Paruh3 hours in horses.
Vol. Distribusi-
Klirens-
Genetik -
Aceprometazine DB01615
small molecule | CAS: 13461-01-3

Aceprometazine is a is a drug with neuroleptic and anti-histamine properties. Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.

Kategori:
Antipsychotic AgentsCentral Nervous System AgentsCentral Nervous System Depressants +13
Target Protein:
Histamine H1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acer macrophyllum pollen Approved DB10734
biotech

Acer macrophyllum pollen is the pollen of the Acer macrophyllum plant. Acer macrophyllum pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acer negundo pollen Approved DB10354
biotech

Acer negundo pollen is the pollen of the Acer negundo plant. Acer negundo pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acer rubrum pollen Approved DB10475
biotech

Acer rubrum pollen is the pollen of the Acer rubrum plant. Acer rubrum pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acer saccharinum pollen Approved DB10735
biotech

Acer saccharinum pollen is the pollen of the Acer saccharinum plant. Acer saccharinum pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acer saccharum pollen Approved DB10369
biotech

Acer saccharum pollen is the pollen of the Acer saccharum plant. Acer saccharum pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acesulfame DB16868
small molecule | CAS: 33665-90-6

Deskripsi belum tersedia.

Kategori:
Sulfur CompoundsSweetening Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetaminophen Approved DB00316
small molecule | CAS: 103-90-2

Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO).[A176318] It is also used for its antipyretic effe…

Kategori:
Acetaminophen and ProdrugsAmidesAmines +31
Target Protein:
Prostaglandin G/H synthase 2Sodium-dependent serotonin transporterSodium-dependent noradrenaline transporter +3
Waktu ParuhThe half-life for a…
Vol. DistribusiVolume of distribut…
KlirensAdults: 0.27 L/h/kg…
Genetik -
Acetarsol Approved DB13268
small molecule | CAS: 97-44-9

Acetarsol, with the molecular formula N-acetyl-4-hydroxy-m-arsanilic acid, is a pentavalent arsenical compound with antiprotozoal and antihelmintic properties.[L2622] It was first discovered in 1921 by Ernest Fourneau at the Pasteur Institute. It was develope…

Kategori:
Agents Against Leishmaniasis and TrypanosomiasisAlimentary Tract and MetabolismAnti-Infective Agents +8
Waktu ParuhThis pharmacokineti…
Vol. DistribusiThis pharmacokineti…
KlirensThis pharmacokineti…
Genetik -
Acetate DB14511
small molecule | CAS: 71-50-1

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicFatty Acids +2
Target Protein:
Macrophage metalloelastaseCalmodulin-1Superoxide dismutase [Cu-Zn] +19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetazolamide Approved DB00819
small molecule | CAS: 59-66-5

One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacer…

Kategori:
AnticonvulsantsAntiglaucoma AgentsAntiglaucoma Preparations and Miotics +22
Target Protein:
Carbonic anhydrase 1Carbonic anhydrase 2Carbonic anhydrase 4 +5
Waktu Paruh3 to 9 hours
Vol. Distribusi-
Klirens-
Genetik -
Acetic acid Approved DB03166
small molecule | CAS: 64-19-7

Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that …

Kategori:
AcetatesAcids, AcyclicAnti-Bacterial Agents +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 78887-71-5

Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People With Pulmonary Hypertension Who Have Impaired RV Fu…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 541-50-4

Deskripsi belum tersedia.

Kategori:
Keto AcidsKetone BodiesKetones
Target Protein:
Fumarylacetoacetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetoacetyl-CoA DB03059
small molecule | CAS: 1420-36-6

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +7
Target Protein:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialAcetyl-CoA acetyltransferaseShort-chain specific acyl-CoA dehydrogenase, mitochondrial +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetohexamide Approved DB00414
small molecule | CAS: 968-81-0

A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.

Kategori:
Alimentary Tract and MetabolismAmidesBenzene Derivatives +13
Target Protein:
ATP-sensitive inward rectifier potassium channel 1ATP-binding cassette sub-family C member 8
Waktu ParuhElimination half-li…
Vol. Distribusi-
Klirens-
Genetik -
Acetohydroxamic acid Approved DB00551
small molecule | CAS: 546-88-3

Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not a…

Kategori:
AminesEnzyme InhibitorsGenito Urinary System and Sex Hormones +5
Target Protein:
Urease subunit alphaMacrophage metalloelastase
Waktu Paruh5-10 hours in patie…
Vol. Distribusi-
Klirens-
Genetik -
Acetomenaphthone Approved DB19387
small molecule | CAS: 573-20-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetophenazine Approved DB01063
small molecule | CAS: 2751-68-0

Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor.

Kategori:
Antipsychotic AgentsCentral Nervous System DepressantsDopamine Antagonists +8
Target Protein:
D(2) dopamine receptorAndrogen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetophenone DB04619
small molecule | CAS: 98-86-2

Deskripsi belum tersedia.

Kategori:
DermatologicalsKetonesPhotosensitizing Agents +1
Target Protein:
R-specific alcohol dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetorphine DB01469
small molecule | CAS: 25333-77-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetoxolone DB13640
small molecule | CAS: 6277-14-1

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismDrugs for Acid Related DisordersDrugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetrizoic acid DB09347
small molecule | CAS: 85-36-9

Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it is the first monomeric ionic compound used as an X-ray contrast agent.[A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in …

Kategori:
Acids, CarbocyclicAminobenzoatesBenzene Derivatives +9
Waktu ParuhWhen water-soluble …
Vol. Distribusi-
Klirens-
Genetik -
Acetyl chloride DB14623
small molecule | CAS: 75-36-5

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAnionsChlorine Compounds +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
ActVA 6 protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 616204-22-9

Argireline has been used in trials studying the treatment of wrinkles.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 145576-25-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetyl sulfisoxazole Approved DB14033
small molecule | CAS: 80-74-0

Sulfisoxazole acetyl is an ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, _dihydropteroate synthas…

Kategori:
AmidesAminesAniline Compounds +13
Target Protein:
Dihydropteroate synthase
Waktu ParuhThe serum half-life…
Vol. DistribusiThe sulfonamides ar…
KlirensThe clearance of su…
Genetik -
small molecule | CAS: 543-24-8

Deskripsi belum tersedia.

Target Protein:
Glycine oxidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetylcholine Approved DB03128
small molecule | CAS: 51-84-3

A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is gen…

Kategori:
AminesAntiglaucoma Preparations and MioticsBiogenic Amines +12
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acetylcysteine Approved DB06151
small molecule | CAS: 616-91-1

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed re…

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +19
Target Protein:
Glutathione synthetaseCystine/glutamate transporterNAPQI (N-acetyl-p-benzoquinone imine) +8
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe volume of distr…
KlirensAcetylcysteine has …
Genetik -
small molecule | CAS: 38520-57-9

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 2101–2150 dari 15718
Sebelumnya Halaman 43 / 315 Berikutnya