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11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (11778)

Halaman 40 / 236
small molecule | CAS: 71031-08-8

Deskripsi belum tersedia.

Target Protein:
Chondroitinase-AC
Waktu Paruh-
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Genetik -
small molecule | CAS: 14687-15-1

Deskripsi belum tersedia.

Target Protein:
Mannose-binding protein CChondroitinase-AC
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Alpha-amylase 2BMaltose binding protein
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Genetik -
small molecule | CAS: 125769-41-7

Deskripsi belum tersedia.

Kategori:
Acids, Carbocyclic
Target Protein:
Chymotrypsinogen B
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Ribose-phosphate pyrophosphokinase
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Aconitate hydratase, mitochondrial
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small molecule | CAS: 105743-53-1

Deskripsi belum tersedia.

Target Protein:
Branched-chain-amino-acid aminotransferase
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small molecule | CAS: 103963-66-2

alpha-methylthiofentanyl is an opioid analgesic that is an analog of fentanyl.

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small molecule | CAS: 14215-68-0

The N-acetyl derivative of galactosamine. [PubChem]

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small molecule | CAS: 604-59-1

Deskripsi belum tersedia.

Kategori:
BenzopyransChromonesFlavonoids +2
Target Protein:
DNA-dependent protein kinase catalytic subunitAromataseCytochrome P450 1A2
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alpha-Pinene DB15573
small molecule | CAS: 80-56-8

Deskripsi belum tersedia.

Kategori:
Bridged-Ring CompoundsMonoterpenesTerpenes
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
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alpha-Tocopherol acetate Approved DB14003
small molecule | CAS: 7695-91-2

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is conside…

Kategori:
AntioxidantsBenzopyransBiological Factors +16
Target Protein:
Free radicals
Waktu ParuhThe apparent half-l…
Vol. DistribusiWhen three particul…
KlirensWhen three specific…
Genetik -
alpha-Tocopherol succinate Approved DB14001
small molecule | CAS: 4345-03-3

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is conside…

Kategori:
AntioxidantsBenzopyransBiological Factors +12
Target Protein:
SEC14-like protein 3SEC14-like protein 2Nuclear receptor subfamily 1 group I member 2 +5
Waktu Paruh_In addition to any…
Vol. Distribusi_In addition to any…
Klirens_In addition to any…
Genetik -
small molecule | CAS: 17199-58-5

A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]

Kategori:
AnalgesicsCentral Nervous System AgentsCentral Nervous System Depressants +6
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Alphamethadol DB01498
small molecule | CAS: 17199-54-1

Deskripsi belum tersedia.

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Alphaprodine DB13160
small molecule | CAS: 77-20-3

Deskripsi belum tersedia.

Kategori:
AnalgesicsCentral Nervous System AgentsCentral Nervous System Depressants +6
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Genetik -
biotech

Deskripsi belum tersedia.

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Alprazolam Approved DB00404
small molecule | CAS: 28981-97-7

Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiaz…

Kategori:
AminesAnti-Anxiety AgentsBenzazepines +25
Target Protein:
GABA(A) ReceptorTranslocator proteinGABA(A) Receptor Benzodiazepine Binding Site
Waktu ParuhAlprazolam has a me…
Vol. DistribusiAlprazolam has a vo…
KlirensA 0.8 mg oral dose …
Genetik -
Alprostadil Approved DB00770
small molecule | CAS: 745-65-3

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppositor…

Kategori:
AutacoidsBiological FactorsCardiac Therapy +27
Target Protein:
Thromboxane A2 receptorProstaglandin E2 receptor EP1 subtypeProstaglandin E2 receptor EP2 subtype +3
Waktu ParuhIn healthy adults a…
Vol. DistribusiThe volume of distr…
KlirensIn patients with er…
Genetik -
Alrizomadlin DB17549
small molecule | CAS: 1818393-16-6

Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]

Target Protein:
E3 ubiquitin-protein ligase Mdm2Cellular tumor antigen p53
Waktu Paruh-
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ALS-08 DB05705
small molecule

ALS-08 is a proprietary creatine-derivative that is being developed as a potential therapeutic for amyotrophic lateral sclerosis (ALS). It is being developed by Avicena Group, Inc.

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Alsactide DB13298
small molecule | CAS: 34765-96-3

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsDiagnostic AgentsHormones +12
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ALT-2074 DB05631
small molecule | CAS: 173026-17-0

An organoselenium drug previously studied by Oxis International in Phase-II clinical trials for ulcerative colitis patients. Some indications of efficacy were demonstrated. BXT-51072 has enthusiastic endorsement for treatment in cardiovascular indications, pr…

Kategori:
Selenium Compounds
Target Protein:
Nitric oxide synthase, inducible
Waktu Paruh2.08 (+/-0.17) hour…
Vol. Distribusi-
Klirens24.15 (+/-2.38) (ml…
Genetik -
ALT-801 DB15386
biotech | CAS: 1188450-53-4

ALT-801 is under investigation in clinical trial NCT01478074 (ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +8
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ALT-P7 DB17220
biotech

Deskripsi belum tersedia.

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Alteplase Approved DB00009
biotech | CAS: 105857-23-6

Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of…

Kategori:
Agents causing angioedemaAmino Acids, Peptides, and ProteinsAnticoagulants +19
Target Protein:
PlasminogenFibrinogen alpha chainFibrinogen gamma chain +1
Waktu ParuhAlteplase has an in…
Vol. DistribusiThe initial volume …
KlirensAlteplase has a pla…
Genetik -
Altiratinib DB17191
small molecule | CAS: 1345847-93-9

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +1
Target Protein:
High affinity nerve growth factor receptorNT-3 growth factor receptorVascular endothelial growth factor receptor 2 +2
Waktu Paruh-
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Altrenogest DB11372
small molecule | CAS: 850-52-2

Altrenogest, also known as allyltrenbolone, is a steroidal progestin that is widely used in veterinary medicine to suppress estrus in animals.

Kategori:
Adrenal Cortex HormonesEstranesEstrenes +6
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Altropane DB04947
small molecule | CAS: 180468-34-2

Boston Life Sciences (BLS) is developing Altropane as a potential radio-imaging agent to be used with single photon emission tomography (SPECT), for the early diagnosis of Parkinson's disease (PD) and attention deficit hyperactivity disorder (ADHD).

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +2
Target Protein:
Sodium-dependent dopamine transporter
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Altropane I-123 DB15144
small molecule | CAS: 208517-65-1

Altropane I-123 is under investigation in clinical trial NCT01950468 (A Cross-Over, Multi-Center Trial to Evaluate the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes).

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Aluminium Approved DB01370
small molecule | CAS: 7429-90-5

A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.

Kategori:
Aluminium CompoundsAluminum and magnesium containing antacidsAntacids +6
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1Kallikrein-1Amyloid-beta precursor protein +1
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small molecule | CAS: 19022-77-6

Aluminium acetoacetate is an aluminum containing antacid.

Kategori:
Alimentary Tract and MetabolismAluminium CompoundsAluminum and magnesium containing antacids +5
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small molecule | CAS: 15930-12-8

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsOtologicalsSensory Organs
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Genetik -
small molecule | CAS: 24818-79-9

Deskripsi belum tersedia.

Kategori:
Agents Causing Muscle ToxicityFibric AcidsLipid Modifying Agents +2
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small molecule | CAS: 41354-48-7

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAlkaliesAluminium Compounds +12
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small molecule | CAS: 7047-84-9

Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of …

Kategori:
Fatty AcidsLipids
Target Protein:
Troponin C, slow skeletal and cardiac musclesNon-selective voltage-gated ion channel VDAC1Voltage-dependent anion-selective channel protein 2 +1
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small molecule | CAS: 1976-28-9

Deskripsi belum tersedia.

Kategori:
Lipid Modifying AgentsLipid Modifying Agents, PlainNicotinic Acid and Derivatives
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Aluminium phosphate Approved DB14517
small molecule | CAS: 7784-30-7

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAdjuvants, Immunologic +16
Target Protein:
SerotransferrinSodium/potassium-transporting ATPase subunit alpha-1Kallikrein-1 +1
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Genetik -
small molecule | CAS: 637-12-7

Deskripsi belum tersedia.

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Aluminum cation DB14519
small molecule | CAS: 22537-23-1

Deskripsi belum tersedia.

Kategori:
Polyvalent cation containing laxatives, antacids, oral supplements
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Aluminum chloride Approved DB11081
small molecule | CAS: 7446-70-0

Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. It is used in various chemical applications as a Lewis base, with anhydrous a…

Kategori:
Aluminium CompoundsAnti-Acne PreparationsAnti-Acne Preparations for Topical Use +10
Target Protein:
Glutamate dehydrogenase 1, mitochondrial
Waktu ParuhFollowing oral admi…
Vol. DistribusiFollowing oral admi…
KlirensFollowing oral admi…
Genetik -
Aluminum chlorohydrate Approved DB11573
small molecule | CAS: 12359-72-7

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydr…

Kategori:
AlkaliesAluminium CompoundsAnions +12
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Aluminum hydroxide Approved DB06723
small molecule | CAS: 21645-51-2

Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandi…

Kategori:
Adjuvants, ImmunologicAlimentary Tract and MetabolismAlkalies +17
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Aluminum sesquichlorohydrate Approved DB11108
small molecule

Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts [A31171].

Kategori:
AlkaliesAluminium CompoundsAnions +6
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Aluminum subacetate Approved DB15679
small molecule | CAS: 142-03-0

Deskripsi belum tersedia.

Kategori:
Astringents
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small molecule | CAS: 174514-58-0

Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent [L2705], [L2706]. It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the po…

Target Protein:
Sweat ducts
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small molecule | CAS: 173762-83-9

Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.

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small molecule

Aluminum zirconium pentachlorohydrex gly, or Aluminum Zirconium Tetrachlorohydrex Glycine, is commonly used as an antiperspirant in many deodorant products. It is a coordination complex of Aluminum Zirconium pentachlorohydrate and glycine. Its anhydrous form …

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small molecule | CAS: 134375-99-8

Aluminum zirconium trichlorohydrex gly is a common active ingredient in deodorant and antiperspirant products for the over-the-counter use. It is consisted of a mixture of monomeric and polymeric Zr4+ and Al3+ complexes with hydroxide, chloride and glycine. T…

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