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12560

Total database: 17430
Struktur (SMILES)
9109 (72.5%)
Target
6912 (55.0%)
Genomik
109 (0.9%)
Referensi
12560 (100.0%)

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Hasil Pencarian (12560)

Halaman 38 / 252
Acotiamide DB12482
small molecule | CAS: 185106-16-5

Acotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.

Kategori:
Acids, CarbocyclicAlimentary Tract and MetabolismAmides +10
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Acoziborole DB13086
small molecule | CAS: 1266084-51-8

SCYX-7158 has been used in trials studying the treatment of Trypanosomiasis, Parasitic Diseases, Protozoan Infections, and Trypanosomiasis, African.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +1
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ACP-015 DB17824
biotech

Deskripsi belum tersedia.

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ACR-16 DB05371
small molecule

ACR-16 is under investigation by NeuroSearch. ACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled trial in patients with Huntington’s disease as well as in three Phase Ib studies within Huntington’s disease, …

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ACR325 DB05196
small molecule

ACR325 is developed for the treatment of Parkinson’s disease and psychoses, including bipolar disorder, for which disease existing therapies have only limited effect and considerable adverse side effects. ACR325 is a dopaminergic stabiliser, which has demonst…

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small molecule | CAS: 89459-25-6

Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.

Kategori:
Antineoplastic AgentsEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +2
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Acriflavine DB13373
small molecule | CAS: 65589-70-0

Deskripsi belum tersedia.

Kategori:
AcridinesAminoacridinesAnti-Infective Agents +10
Target Protein:
Gag-Pol polyprotein
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Acrivastine Approved DB09488
small molecule | CAS: 87848-99-5

Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histami…

Kategori:
Antihistamines for Systemic UseDrugs that are Mainly Renally ExcretedHistamine Agents +7
Target Protein:
Histamine H1 receptor
Waktu ParuhThe mean terminal h…
Vol. Distribusi0.46 ± 0.05 L/kg
Klirens2.9 ± 0.7 mL/min/kg
Genetik -
Acrizanib DB16081
small molecule | CAS: 1229453-99-9

Acrizanib is under investigation in clinical trial NCT02355028 (LHA510 Proof-of-concept Study as a Maintenance Therapy for Patients With Wet Age-related Macular Degeneration).

Kategori:
Compounds used in a research, industrial, or household settingEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +5
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Acrylic Acid DB02579
small molecule | CAS: 79-10-7

A ?,?-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.

Kategori:
Acids, AcyclicCompounds used in a research, industrial, or household settingEquipment and Supplies +3
Target Protein:
Beta-lactamase SHV-1
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ACT-451840 DB13054
small molecule | CAS: 1839508-99-4

ACT-451840 has been used in trials studying Malaria.

Kategori:
Acids, AcyclicAcrylatesAmides
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Actelion-1 DB05367
small molecule

Actelion-1 is a tissue-targeting Endothelin Receptor Antagonist that has been discovered by Actelion Pharmaceuticals.

Kategori:
AmidesEndothelin A Receptor AntagonistsEndothelin B Receptor Antagonists +3
Target Protein:
Endothelin-1 receptor
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Activated charcoal Approved DB09278
small molecule | CAS: 64365-11-3

Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, p…

Kategori:
AdsorptionAlimentary Tract and MetabolismAnions +14
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Actoxumab DB16376
biotech | CAS: 1245634-25-6

Actoxumab is under investigation in clinical trial NCT01241552 (A Study of MK-3415, MK-6072, and MK-3415A in Participants Receiving Antibiotic Therapy for Clostridium Difficile Infection (MK-3415A-001)).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Neutralizing +6
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ACTUS-101 DB17658
biotech

Deskripsi belum tersedia.

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ACTX-401 DB18504
biotech

ACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing the human immunoglobulin u-binding protein 2 cDNA.

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Acumapimod DB15448
small molecule | CAS: 836683-15-9

Acumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
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ACV tripeptide DB02025
small molecule | CAS: 32467-88-2

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
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ACY001 DB06355
biotech

Deskripsi belum tersedia.

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Acyclovir Approved DB00787
small molecule | CAS: 59277-89-3

Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis.[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of the…

Kategori:
Acyclovir and prodrugAnti-Infective AgentsAntiinfectives for Systemic Use +28
Target Protein:
DNA polymerase catalytic subunitDNA polymerase catalytic subunit
Waktu ParuhThe clearance of ac…
Vol. DistribusiThe volume of distr…
KlirensThe renal clearance…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-lactamaseBeta-lactamaseRegulatory protein BlaR1
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Acyline DB11906
small molecule | CAS: 170157-13-8

Acyline has been investigated for the prevention and treatment of Hypogonadism and Contraception.

Kategori:
Amino Acids, Peptides, and ProteinsGonadotropin-Releasing Hormone, antagonists & inhibitorsHormone Antagonists +2
Target Protein:
Gonadotropin-releasing hormone receptor
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AD 337 DB05725
small molecule

AD 337 was under investigation in clinical trial NCT00377039 (A Multicentre Trial to Determine the Efficacy and Safety of AD-337 in the Treatment of Fibromyalgia). The drug was created by Sosei pharmaceuticals to treat Fibromyalgia in female patients.

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AD-114 DB18285
biotech

Deskripsi belum tersedia.

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Ad-CEA vaccine DB17581
biotech

Ad-CEA vaccine is a cancer immunotherapy composed of carcinoembryonic antigen (CEA). Ad-CEA vaccine is under investigation in clinical trial NCT03050814 (Standard of Care Alone or in Combination With Ad-cea Vaccine and Avelumab in People With Previously Untre…

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Ad-ISF35 DB17181
biotech

Deskripsi belum tersedia.

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Ad-SGE-REIC DB17183
biotech

Deskripsi belum tersedia.

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Ad5-nCoV DB15655
biotech

Ad5-nCoV is a recombinant adenovirus type-5 vector (Ad5) vaccine currently being investigated for prophylaxis against SARS-CoV-2.[L12675,L12678] It is being developed by CanSino Biologics Inc., in partnership with the Beijing Institute of Biotechnology, who i…

Kategori:
Experimental Unapproved Treatments for COVID-19
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Adafosbuvir DB14906
small molecule | CAS: 1613589-09-5

Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).

Kategori:
AcidsAcids, NoncarboxylicAmino Acids +13
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biotech | CAS: 1458687-85-8

Adagloxad simolenin is under investigation in clinical trial NCT03562637 (Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC).

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Adagrasib Approved DB15568
small molecule | CAS: 2326521-71-3

Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations.[A254941] However, the development of KRAS inhibitors has …

Kategori:
Antineoplastic AgentsAntineoplastic Agents, ImmunologicalAntineoplastic and Immunomodulating Agents +21
Target Protein:
GTPase KRas
Waktu ParuhAdagrasib has a ter…
Vol. DistribusiAdagrasib has an ap…
KlirensAdagrasib has an ap…
Genetik -
Adalimumab Approved DB00051
biotech | CAS: 331731-18-1

Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and ap…

Kategori:
Agents reducing cytokine levelsAmino Acids, Peptides, and ProteinsAnti-Inflammatory Agents +19
Target Protein:
Tumor necrosis factor
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe distribution vo…
KlirensThe single-dose pha…
Genetik -
ADAM I-123 DB19213
small molecule | CAS: 305352-16-3

ADAM I-123 is under investigation in clinical trial NCT01160263 (Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls).

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small molecule

Deskripsi belum tersedia.

Target Protein:
Camphor 5-monooxygenase
Waktu Paruh-
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small molecule

Deskripsi belum tersedia.

Target Protein:
Camphor 5-monooxygenase
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Adamantanone DB02125
small molecule | CAS: 700-58-3

Deskripsi belum tersedia.

Kategori:
Bridged-Ring CompoundsCycloparaffins
Target Protein:
Camphor 5-monooxygenase
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Adapalene Approved DB00210
small molecule | CAS: 106685-40-9

Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with _Cutibacterium acnes_ (also known as…

Kategori:
Anti-Acne PreparationsAnti-Acne Preparations for Topical UseAnti-Inflammatory Agents +5
Target Protein:
Retinoic acid receptor betaRetinoic acid receptor gammaRetinoic acid receptor RXR-beta +6
Waktu ParuhIn one clinical stu…
Vol. Distribusi-
KlirensAdapalene is rapidl…
Genetik -
Adavosertib DB11740
small molecule | CAS: 955365-80-7

MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.

Kategori:
Enzyme InhibitorsPyrimidines
Target Protein:
Wee1-like protein kinase
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ADC4022 DB05195
small molecule

ADC4022 is an investigational medicine for the treatment of Chronic Obstructive Pulmonary Disease (COPD) and severe asthma.

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Adebrelimab DB16412
biotech | CAS: 2247114-85-6

Adebrelimab is under investigation in clinical trial NCT03711305 (Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-stage (ES) Small Cell Lung Cancer (SCLC)).

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Adecatumumab DB05006
biotech | CAS: 503605-66-1

Adecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity to epithelial cell adhesion molecule (EpCAM). EpCAM (CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types,…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +14
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Adefovir DB13868
small molecule | CAS: 106941-25-7

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsAntiviral AgentsEnzyme Inhibitors +8
Target Protein:
Protein PDNA polymerase catalytic subunit
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Adegramotide DB17248
small molecule | CAS: 1252802-98-4

Deskripsi belum tersedia.

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Adelmidrol DB16083
small molecule | CAS: 1675-66-7

Adelmidrol is under investigation in clinical trial NCT01420510 (Saginil in vs. Placebo for Gynecologic Oncology Patients Affected by Vaginitis).

Kategori:
Acids, AcyclicFatty AcidsLipids
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Adenine Approved DB00173
small molecule | CAS: 73-24-5

A purine base and a fundamental unit of adenine nucleotides.

Kategori:
Dietary SupplementsHeterocyclic Compounds, Fused-RingPurines +2
Target Protein:
Adenine phosphoribosyltransferaseDNAS-methyl-5'-thioadenosine phosphorylase +9
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Adenosine Approved DB00640
small molecule | CAS: 58-61-7

The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were not described in literature until the 1940s.[A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] thou…

Kategori:
Adenosine, antagonists & inhibitorsAgents producing tachycardiaAlkenes +32
Target Protein:
Adenosine receptor A1Adenosine receptor A2aAdenosine receptor A2b +1
Waktu ParuhThe half life of ad…
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik -
small molecule | CAS: 1053-73-2

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesHeterocyclic Compounds, Fused-RingIsomerism +5
Target Protein:
Heparan sulfate glucosamine 3-O-sulfotransferase 1Sulfotransferase 2B1Non-secretory ribonuclease +9
Waktu Paruh-
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small molecule | CAS: 3768-14-7

Deskripsi belum tersedia.

Kategori:
5'-Nucleotidase, antagonists & inhibitorsAdenine NucleotidesEnzyme Inhibitors +6
Target Protein:
5'-nucleotidaseDNARibose-phosphate pyrophosphokinase +2
Waktu Paruh-
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small molecule | CAS: 485-84-7

5'-Adenylic acid, monoanhydride with sulfuric acid. The initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS.

Kategori:
Adenine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4
Target Protein:
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1ATP sulfurylase (Sulfate adenylyltransferase)
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small molecule | CAS: 35094-46-3

A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.

Kategori:
Adenine NucleotidesAffinity LabelsCompounds used in a research, industrial, or household setting +8
Target Protein:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2Synapsin-1Branched-chain alpha-ketoacid dehydrogenase kinase +11
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Menampilkan 1851–1900 dari 12560
Sebelumnya Halaman 38 / 252 Berikutnya