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14494

Total database: 17430
Struktur (SMILES)
9687 (66.8%)
Target
7525 (51.9%)
Genomik
112 (0.8%)
Referensi
14494 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (14494)

Halaman 37 / 290
small molecule

Deskripsi belum tersedia.

Target Protein:
ActVA 6 protein
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small molecule | CAS: 616204-22-9

Argireline has been used in trials studying the treatment of wrinkles.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
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small molecule | CAS: 145576-25-6

Deskripsi belum tersedia.

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Acetyl sulfisoxazole Approved DB14033
small molecule | CAS: 80-74-0

Sulfisoxazole acetyl is an ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, _dihydropteroate synthas…

Kategori:
AmidesAminesAniline Compounds +13
Target Protein:
Dihydropteroate synthase
Waktu ParuhThe serum half-life…
Vol. DistribusiThe sulfonamides ar…
KlirensThe clearance of su…
Genetik -
small molecule | CAS: 543-24-8

Deskripsi belum tersedia.

Target Protein:
Glycine oxidase
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Acetylcarnitine Approved DB08842
small molecule | CAS: 3040-38-8

Acetylcarnitine is an investigational drug in the United states, Italy, United Kingdom, China, Israel, and Norway, and it is approved in Italy, Portugal, Argentina, Chile, Philippines, Australia, and India. Acetylcarnitine can be synthesized, but it is also n…

Kategori:
AminesCentral Nervous System AgentsMicronutrients +6
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Acetylcholine Approved DB03128
small molecule | CAS: 51-84-3

A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is gen…

Kategori:
AminesAntiglaucoma Preparations and MioticsBiogenic Amines +12
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3 +2
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Acetylcysteine Approved DB06151
small molecule | CAS: 616-91-1

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed re…

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +19
Target Protein:
Glutathione synthetaseCystine/glutamate transporterNAPQI (N-acetyl-p-benzoquinone imine) +8
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe volume of distr…
KlirensAcetylcysteine has …
Genetik -
small molecule | CAS: 38520-57-9

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +2
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Genetik -
small molecule | CAS: 36330-79-7

Deskripsi belum tersedia.

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Genetik -
small molecule | CAS: 2736440-65-4

Deskripsi belum tersedia.

Kategori:
Experimental Unapproved Treatments for COVID-19
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small molecule | CAS: 49793-39-7

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +11
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Acetyldigitoxin Approved DB00511
small molecule | CAS: 1111-39-3

Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.

Kategori:
Antiarrhythmic agentsCarbohydratesCardanolides +12
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1
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Acetyldigoxin DB13691
small molecule | CAS: 5511-98-8

Deskripsi belum tersedia.

Kategori:
Antiarrhythmic agentsCarbohydratesCardanolides +15
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small molecule | CAS: 3861-72-1

Deskripsi belum tersedia.

Kategori:
Cough and Cold PreparationsOpium Alkaloids and Derivatives
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Acetyldinaline DB16142
small molecule | CAS: 58338-59-3

Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).

Kategori:
Acids, CarbocyclicAmidesAmines +8
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Acetylene Approved DB15906
small molecule | CAS: 74-86-2

Deskripsi belum tersedia.

Kategori:
AlkynesHydrocarbons, Acyclic
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Acetyleneurea DB03533
small molecule | CAS: 496-46-8

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingImidazoles
Target Protein:
Streptavidin
Waktu Paruh-
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Genetik -
small molecule | CAS: 17427-14-4

Deskripsi belum tersedia.

Kategori:
Central Nervous System DepressantsHypnotics and SedativesNervous System +1
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Acetylleucine DB13226
small molecule | CAS: 99-15-0

Used for treating vestibular-related imbalance and vertigo.

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Peptides, and Proteins +2
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Genetik -
small molecule | CAS: 110044-82-1

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsCysteine Proteinase InhibitorsEnzyme Inhibitors +4
Target Protein:
Proteasome subunit alpha type-7
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Acetylphosphate DB02897
small molecule

Deskripsi belum tersedia.

Target Protein:
GDP-L-fucose synthasePhosphate acetyltransferase
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Acetylsalicylic acid Approved DB00945
small molecule | CAS: 50-78-2

Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and i…

Kategori:
Acids, CarbocyclicAgents causing angioedemaAgents causing hyperkalemia +38
Target Protein:
Prostaglandin G/H synthase 13-hydroxy-3-methylglutaryl-coenzyme A reductaseProstaglandin G/H synthase 2 +17
Gen Terkait:
CYP2C9 ITGB3 LTC4S
Waktu ParuhThe half-life of AS…
Vol. DistribusiThis drug is distri…
KlirensThe clearance rate …
Genetik 3 Varian
ACG-801 DB17659
biotech

Deskripsi belum tersedia.

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Acheta domesticus Approved DB10866
biotech

House cricket allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Genetik -
small molecule | CAS: 68957-71-1

Deskripsi belum tersedia.

Kategori:
ArylsulfonatesArylsulfonic AcidsBenzene Derivatives +3
Target Protein:
Bifunctional purine biosynthesis protein ATIC
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Acifluorfen DB07338
small molecule | CAS: 50594-66-6

Acifluorfen is a protoporphyrinogen oxidase inhibitor.

Kategori:
Acids, CarbocyclicAgrochemicalsBenzene Derivatives +6
Target Protein:
Protoporphyrinogen oxidaseProtoporphyrinogen oxidase
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Acimtamig DB18674
biotech | CAS: 2738880-26-5

Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
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Acipimox Approved DB09055
small molecule | CAS: 51037-30-0

Acipimox is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the…

Kategori:
Agents Causing Muscle ToxicityHypolipidemic AgentsLipid Modifying Agents +3
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Acitretin Approved DB00459
small molecule | CAS: 55079-83-9

An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.

Kategori:
AlkenesAntipsoriaticsAntipsoriatics for Systemic Use +17
Target Protein:
Retinoic acid receptor RXR-alphaSignal transducer and activator of transcription 3Retinoic acid receptor alpha +6
Waktu Paruh49 hours (range 33 …
Vol. Distribusi-
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Genetik -
Aclarubicin DB11617
small molecule | CAS: 57576-44-0

Deskripsi belum tersedia.

Kategori:
AnthracyclinesAnthracyclines and Related SubstancesAntibiotics, Antineoplastic +9
Target Protein:
DNA topoisomerase 2-alphaDNA topoisomerase 2-beta
Waktu Paruh-
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Genetik -
Aclerastide DB12631
small molecule | CAS: 227803-63-6

Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.

Kategori:
Amino Acids, Peptides, and ProteinsAngiotensinsAutacoids +10
Target Protein:
Proto-oncogene Mas
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Aclidinium Approved DB08897
small molecule | CAS: 727649-81-2

Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.

Kategori:
Adrenergics, InhalantsAgents producing tachycardiaAgents to Treat Airway Disease +9
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3 +2
Waktu ParuhPlasma half-life = …
Vol. DistribusiFollowing IV admini…
KlirensTotal clearance, IV…
Genetik -
Aclimostat DB16079
small molecule | CAS: 2082752-83-6

Aclimostat is under investigation in clinical trial NCT03254368 (Study to Assess the Effects and Safety of ZGN-1061 in Overweight and Obese Participants With Type 2 Diabetes).

Kategori:
Anti-Obesity AgentsAzetinesEnzyme Inhibitors +1
Target Protein:
Methionine aminopeptidase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Acolbifene DB16080
small molecule | CAS: 182167-02-8

Acolbifene is under investigation in clinical trial NCT01452373 (Dehydroepiandrosterone (DHEA) + Acolbifene Against Vasomotor Symptoms (Hot Flushes) in Postmenopausal Women).

Target Protein:
Estrogen receptor
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Acoltremon DB19202
small molecule | CAS: 68489-09-8

Acoltremon is under investigation in clinical trial NCT05493111 (A Long-term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512).

Kategori:
AlcoholsAmidesAmines +10
Target Protein:
Transient receptor potential cation channel subfamily M member 8
Waktu Paruh-
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Genetik -
Aconiazide DB17731
small molecule | CAS: 13410-86-1

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsDrugs for Treatment of Tuberculosis +3
Waktu Paruh-
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Genetik -
Aconitate Ion DB04351
small molecule

Deskripsi belum tersedia.

Target Protein:
Aconitate hydratase, mitochondrialAconitate hydratase B
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Genetik -
Acoramidis DB17999
small molecule | CAS: 1446711-81-4

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmyloidosis, prevention & controlBenzene Derivatives
Target Protein:
Transthyretin
Waktu Paruh-
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Genetik -
biotech

Acorus calamus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Acotiamide DB12482
small molecule | CAS: 185106-16-5

Acotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.

Kategori:
Acids, CarbocyclicAlimentary Tract and MetabolismAmides +10
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Acoziborole DB13086
small molecule | CAS: 1266084-51-8

SCYX-7158 has been used in trials studying the treatment of Trypanosomiasis, Parasitic Diseases, Protozoan Infections, and Trypanosomiasis, African.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +1
Waktu Paruh-
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ACP-015 DB17824
biotech

Deskripsi belum tersedia.

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Genetik -
ACR-16 DB05371
small molecule

ACR-16 is under investigation by NeuroSearch. ACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled trial in patients with Huntington’s disease as well as in three Phase Ib studies within Huntington’s disease, …

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ACR325 DB05196
small molecule

ACR325 is developed for the treatment of Parkinson’s disease and psychoses, including bipolar disorder, for which disease existing therapies have only limited effect and considerable adverse side effects. ACR325 is a dopaminergic stabiliser, which has demonst…

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Acremonium strictum Approved DB10423
biotech

Acremonium strictum is a fungus which can provoke allergic reactions. Acremonium strictum extract is used in allergenic testing.

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small molecule | CAS: 89459-25-6

Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.

Kategori:
Antineoplastic AgentsEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +2
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Acriflavine DB13373
small molecule | CAS: 65589-70-0

Deskripsi belum tersedia.

Kategori:
AcridinesAminoacridinesAnti-Infective Agents +10
Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
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Genetik -
Acrivastine Approved DB09488
small molecule | CAS: 87848-99-5

Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histami…

Kategori:
Antihistamines for Systemic UseDrugs that are Mainly Renally ExcretedHistamine Agents +7
Target Protein:
Histamine H1 receptor
Waktu ParuhThe mean terminal h…
Vol. Distribusi0.46 ± 0.05 L/kg
Klirens2.9 ± 0.7 mL/min/kg
Genetik -
Acrizanib DB16081
small molecule | CAS: 1229453-99-9

Acrizanib is under investigation in clinical trial NCT02355028 (LHA510 Proof-of-concept Study as a Maintenance Therapy for Patients With Wet Age-related Macular Degeneration).

Kategori:
Compounds used in a research, industrial, or household settingEnzyme InhibitorsHeterocyclic Compounds, Fused-Ring +5
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Genetik -
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