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3253

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2451 (75.3%)
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1833 (56.3%)
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35 (1.1%)
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3253 (100.0%)

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Halaman 32 / 66
Insulin degludec Approved DB09564
biotech | CAS: 844439-96-9

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the ac…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +13
Target Protein:
InsulinInsulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhThe half-life after…
Vol. DistribusiUsing a one-compart…
KlirensThe mean apparent c…
Genetik -
Insulin detemir Approved DB01307
biotech | CAS: 169148-63-4

Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenou…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +13
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhAfter subcutaneous …
Vol. DistribusiInsulin detemir has…
KlirensThe apparent cleara…
Genetik -
Insulin glargine Approved DB00047
biotech | CAS: 160337-95-1

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insuli…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsAntimetabolites +18
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Insulin glulisine Approved DB01309
biotech | CAS: 207748-29-6

Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insu…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +15
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhElimination half li…
Vol. Distribusi13 L
Klirens-
Genetik -
Insulin human Approved DB00030
biotech | CAS: 11061-68-0

Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced ins…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +14
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptorCarboxypeptidase E +3
Waktu ParuhSystemic insulin di…
Vol. Distribusi-
Klirens-
Genetik -
Insulin lispro Approved DB00046
biotech | CAS: 133107-64-9

Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptid…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +14
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhAfter subcutaneous …
Vol. DistribusiWhen administered i…
KlirensWhen administered i…
Genetik -
biotech | CAS: 1200440-65-8

Deskripsi belum tersedia.

Kategori:
AlcoholsAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +16
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Insulin pork Approved DB00071
biotech | CAS: 12584-58-6

Insulin isolated from pig pancreas. Composed of alpha and beta chains, processed from pro-insulin. Forms a hexameric structure.

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +13
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Intepirdine DB12680
small molecule | CAS: 607742-69-8

Intepirdine has been used in trials studying the treatment of Alzheimer's Disease.

Kategori:
Heterocyclic Compounds, Fused-RingSulfur Compounds
Target Protein:
5-hydroxytryptamine receptor 6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Interferon alfa-2b Approved DB00105
biotech | CAS: 98530-12-2

Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by …

Kategori:
Adjuvants, ImmunologicAlfa InterferonsAmino Acids, Peptides, and Proteins +24
Target Protein:
Interferon alpha/beta receptor 2Interferon alpha-2Interferon alpha/beta receptor 1
Waktu ParuhThe elimination hal…
Vol. Distribusi-
Klirens-
Genetik -
Interleukin-10 DB12880
biotech

Interleukin-10 has been used in trials studying the prevention and treatment of Vasculitis, Pancreatitis, Bile Duct Diseases, Pancreatic Diseases, and Gallbladder Diseases, among others.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Intermedine DB17612
biotech | CAS: 581-05-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsAmino Acids, Peptides, and ProteinsHeterocyclic Compounds, Fused-Ring +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Intetumumab DB12701
biotech | CAS: 725735-28-4

Intetumumab has been used in trials studying the treatment of Melanoma.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Intoplicine DB12868
small molecule | CAS: 125974-72-3

Intoplicine has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Inupadenant DB19129
small molecule | CAS: 2246607-08-7

Inupadenant is under investigation in clinical trial NCT05060432 (Study of EOS-448 With Standard of Care And/or Investigational Therapies in Participants With Advanced Solid Tumors).

Target Protein:
Adenosine receptor A2a
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Invert sugar DB09344
small molecule | CAS: 8013-17-0

Invert sugar is obtained from sugar cane when this is treated with dilute acid or with the invertase enzyme. It is formed by an equal amount of glucose and fructose. It differentiates from sugar cane in the rotation of the polarized light, which in the case o…

Kategori:
Antivaricose TherapyCarbohydratesCariogenic Agents +14
Waktu ParuhThe glucose half-li…
Vol. Distribusi-
Klirens-
Genetik -
Iobenguane Approved DB06704
small molecule | CAS: 80663-95-2

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionu…

Kategori:
AmidinesBenzene DerivativesCompounds used in a research, industrial, or household setting +16
Target Protein:
Sodium-dependent noradrenaline transporter
Waktu ParuhPhysical half life …
Vol. Distribusi-
Klirens-
Genetik -
Iobenguane sulfate I-123 Approved DB09546
small molecule | CAS: 80663-95-2

Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].

Kategori:
Drugs that are Mainly Renally ExcretedRadioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iobitridol Approved DB12407
small molecule | CAS: 136949-58-1

Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodide Approved DB12754
small molecule | CAS: 20461-54-5

Iodide has been investigated for the treatment of Goiter, Nodular.

Kategori:
AnionsElectrolytesIodides +2
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodide I-123 Approved DB09420
small molecule | CAS: 69239-56-1

Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid g…

Kategori:
Diagnostic RadiopharmaceuticalsElementsHalogens +6
Waktu ParuhIodine-123 decays b…
Vol. Distribusi-
Klirens-
Genetik -
Iodide I-131 Approved DB09293
small molecule | CAS: 14914-30-8

Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result o…

Kategori:
Diagnostic RadiopharmaceuticalsIodine (131I) CompoundsRadioactive Therapeutic Agent +3
Waktu ParuhIodine I-131 decays…
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 2420475-06-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodine I-125 DB14804
small molecule | CAS: 14158-31-7

Iodine I-125 is under investigation in clinical trial NCT00079417 (Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodixanol Approved DB01249
small molecule | CAS: 92339-11-2

Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +11
Waktu Paruh2.1 hours. In patie…
Vol. Distribusi* 0.26 L/kg
Klirens-
Genetik -
small molecule | CAS: 123748-56-1

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesHydrocarbons, HalogenatedHydrocarbons, Iodinated +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodohippurate sodium I-123 Approved DB09448
small molecule | CAS: 56254-07-0

Deskripsi belum tersedia.

Kategori:
Diagnostic RadiopharmaceuticalsRenal System
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iodoxamic acid DB13539
small molecule | CAS: 31127-82-9

Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iofetamine I-123 Approved DB09480
small molecule | CAS: 75917-92-9

Deskripsi belum tersedia.

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAmines +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1214283-52-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ioflupane I-123 Approved DB08824
small molecule | CAS: 155798-07-5

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +9
Target Protein:
Sodium-dependent dopamine transporter
Waktu ParuhHalf life is 13.2 h…
Vol. DistribusiCompared to the ent…
Klirens-
Genetik -
small molecule | CAS: 949575-24-0

Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).

Kategori:
AmidesAmino AcidsAmino Acids, Acidic +2
Target Protein:
Glutamate carboxypeptidase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ioforminol DB12439
small molecule | CAS: 1095110-48-7

Ioforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH With or Without PCI.

Kategori:
Acids, AcyclicAcids, CarbocyclicAmides +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iomazenil DB14971
small molecule | CAS: 127985-21-1

Iomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans).

Kategori:
BenzazepinesBenzodiazepinonesHeterocyclic Compounds, Fused-Ring +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iophendylate Approved DB01187
small molecule | CAS: 99-79-6

Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in…

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 873438-87-0

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
IOWH-032 DB12959
small molecule | CAS: 1191252-49-9

Iowh032 has been investigated for the treatment of Cholera, Diarrhea, and Secretory Diarrhea.

Kategori:
Oxazoles
Target Protein:
Cystic fibrosis transmembrane conductance regulator
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ipamorelin DB12370
small molecule | CAS: 170851-70-4

Ipamorelin has been investigated for the treatment of Ileus.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Target Protein:
Growth hormone secretagogue receptor type 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ipatasertib DB11743
small molecule | CAS: 1001264-89-6

Ipatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.

Kategori:
Antineoplastic AgentsEnzyme InhibitorsProtein Kinase Inhibitors +1
Target Protein:
RAC-alpha serine/threonine-protein kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ipecac Approved DB13293
small molecule | CAS: 8012-96-2

Ipecac is obtained from the plant _Cephaelis ipecacuanha_ and contains a number of emetic alkaloids including emetine and cephaeline.[L2753] Ipecac was approved by Health Canada as an OTC but all those products are now discontinued.[L1113] The FDA does not ha…

Kategori:
Agents Causing Muscle ToxicityAntidotesAutonomic Agents +15
Waktu ParuhThe effect of ipeca…
Vol. DistribusiThe volume of distr…
KlirensThe urinary excreti…
Genetik -
Ipilimumab Approved DB06186
biotech | CAS: 477202-00-9

Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4).[L12126] Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntibodies +21
Target Protein:
Cytotoxic T-lymphocyte protein 4
Waktu ParuhIpilimumab has a ha…
Vol. DistribusiThe volume of distr…
KlirensIpilimumab has a cl…
Genetik -
IPL-344 DB16958
small molecule | CAS: 877120-59-7

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ipriflavone DB13618
small molecule | CAS: 35212-22-7

Deskripsi belum tersedia.

Kategori:
BenzopyransBone RemodelingChromones +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
IQP-0528 DB14888
small molecule | CAS: 301297-45-0

IQP-0528 is under investigation in clinical trial NCT03082690 (ImQuest (IQP) DuoGel Phase 1 Pharmacokinetic Study).

Kategori:
Anti-HIV AgentsPyrimidines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Irdabisant DB12900
small molecule | CAS: 1005402-19-6

Irdabisant has been used in trials studying Cognitive Impairment.

Kategori:
Receptors, Histamine H3
Target Protein:
Histamine H3 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Irinotecan Approved DB00762
small molecule | CAS: 97682-44-5

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of [camptothecin], which is extracted from the Chinese tree _Camptotheca acuminate_.[A263376] The bis-piperidine side chain in the structure of irinotecan bestows en…

Kategori:
AlkaloidsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +29
Target Protein:
DNA topoisomerase I, mitochondrialDNA topoisomerase 1
Gen Terkait:
SLCO1B1 UGT1A1 UGT1A7 +2
Waktu ParuhAfter intravenous i…
Vol. DistribusiFollowing intraveno…
KlirensThe mean (± standar…
Genetik 5 Varian
Iron isomaltoside 1000 Approved DB12208
small molecule | CAS: 1370654-58-2

Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney Disease, and Anemia, Iron-Deficiency, among…

Kategori:
CarbohydratesHematinicsHematologic Agents +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Iron protein succinylate Approved DB11209
small molecule | CAS: 250705-13-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino Acids, Peptides, and ProteinsAntianemic Preparations +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
IRX-2 DB05643
biotech | CAS: 951209-71-5

IRX-2 contains a human leukocyte-derived cytokine mixture. It is being investigated to promote or enhance an anti-cancer immune response.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsIntercellular Signaling Peptides and Proteins +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 1551–1600 dari 3253
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