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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Halaman 315 / 349
TBA-7371 DB16243
small molecule | CAS: 1494675-86-3

TBA-7371 is under investigation in clinical trial NCT04176250 (Early Bactericidal Activity of TBA-7371 in Pulmonary Tuberculosis).

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TBAJ-876 DB18807
small molecule

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingQuinolines
Waktu Paruh-
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TBC-3711 DB05407
small molecule | CAS: 349453-49-2

TBC3711 is a next-generation endothelin antagonist that is being studied through oral and intravenous formulations by Encysive Pharmaceuticals.

Kategori:
Endothelin A Receptor AntagonistsEndothelin Receptor AntagonistsSulfur Compounds
Target Protein:
Endothelin-1 receptorEndothelin-1
Waktu Paruh-
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TBI-223 DB18911
small molecule | CAS: 2071265-08-0

TBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).

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TBX-1400 DB18263
biotech

TBX-1400 consists of human donor hematopoietic stem and progenitor cells.

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TBX-3400 DB17370
biotech

TBX-3400 is an investigational cell-based immunotherapy consisting of autologous peripheral blood mononuclear cells (PBMCs) treated ex vivo with TBX-4000, which is a recombinant TAT-MYC fusion protein.[L44281,L44286]

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TC-2216 DB06044
small molecule | CAS: 1159824-71-1

TC-2216 is an investigational novel small molecule that is being developed as an oral treatment for depression and anxiety disorders. TC-2216 showed greater potency than and anti-depressant effects comparable to selective serotonin reuptake inhibitors and tri…

Target Protein:
Neuronal acetylcholine receptor subunit alpha-4Neuronal acetylcholine receptor subunit beta-2
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TC-2696 DB05576
small molecule | CAS: 552302-36-0

Deskripsi belum tersedia.

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TC-5231 DB05333
small molecule

TC-5231 is a small molecule that has been under investigation as an oral treatment for ADHD (Attention Deficit/Hyperactivity Disorder). TC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but in a lower dose than I…

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TC-6987 DB14854
small molecule | CAS: 1196701-27-5

TC-6987 is under investigation in clinical trial NCT01296087 (TC-6987 for the Treatment of Mild to Moderate Asthma).

Target Protein:
Neuronal acetylcholine receptor subunit alpha-7
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TCB-008 DB18352
biotech

TCB-008 is an Allogeneic CD3+ T lymphocyte ex vivo expanded expressing the gamma delta T-cell receptor.

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TCN-202 DB17777
biotech

Deskripsi belum tersedia.

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TD-0903 DB16463
small molecule | CAS: 2412496-23-0

TD-0903 was investigated in clinical trials for its potential to treat acute lung injury (ALI) associated with COVID-19, including NCT04350736, NCT05091723 (a pharmacokinetics study in healthy participants with supplemental oxygenation), and NCT04402866 (focu…

Kategori:
AzetinesExperimental Unapproved Treatments for COVID-19Heterocyclic Compounds, Fused-Ring +1
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TD-2749 DB05905
small molecule | CAS: 863248-59-3

TD-2749 is selective 5-HT4 agonists discovered by Theravance through the application of multivalent drug design in a drug discovery program dedicated to finding new medicines for GI motility disorders such as chronic constipation, constipation-predominant irr…

Target Protein:
5-hydroxytryptamine receptor 4
Waktu Paruh-
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TD101 DB06596
small molecule

TD101, a small interfering RNA (siRNA) designed for the treatment of pachyonychia congenita

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TDI-01 DB19450
small molecule

TDI-01 is a small molecule is being developed by Beijing Tide Pharmaceutical.

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Tea leaf Approved DB10580
biotech

Tea leaf allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
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Tea tree oil DB11218
biotech | CAS: 68647-73-4

Tea tree oil is an essential oil derived mainly from the Australian native plant _Melaleuca alternifolia_ via steam distillation of the of the leaves and terminal branches [A32439]. It may be referred to as _Melaleuca alternifolia_ oil. It has been a popular …

Kategori:
Anti-Infective AgentsAnti-Infective Agents, LocalBiological Products +7
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Tebapivat DB19338
small molecule

Tebapivat is under investigation in clinical trial NCT05490446 (A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-risk Myelodysplastic Syndromes (LR-MDS)).

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Tebentafusp Approved DB15283
biotech | CAS: 1874157-95-5

Tebentafusp is a gp100 peptide-HLA-directed CD3 T cell engager.[L39995] It is a bispecific, fusion protein and first-in-class drug of immune-mobilizing monoclonal T cell receptors against cancer (ImmTACs), a recently developed cancer immunotherapy with a nove…

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +6
Target Protein:
Melanocyte protein PMEL
Waktu ParuhThe median terminal…
Vol. DistribusiThe geometric mean …
KlirensThe geometric mean …
Genetik -
small molecule | CAS: 161715-24-8

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial AgentsAntibacterials for Systemic Use +5
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Tebotelimab DB16685
biotech | CAS: 2245725-04-4

Tebotelimab is under investigation in clinical trial NCT04082364 (Combination Margetuximab, INCMGA00012, MGD013, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/gej Cancer (MAHOGANY)).

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Tecadenoson DB04954
small molecule | CAS: 204512-90-3

Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for the conversion of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm. It is being developed by CV Therapeutics, Inc.

Kategori:
Heterocyclic Compounds, Fused-RingNeurotransmitter AgentsNucleic Acids, Nucleotides, and Nucleosides +7
Target Protein:
Adenosine receptor A1
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Tecarfarin DB12823
small molecule | CAS: 867257-26-9

Tecarfarin has been used in trials studying the prevention of Thrombosis and Thromboembolism.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzopyrans +5
Target Protein:
Vitamin K epoxide reductase complex subunit 1
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Tecastemizole DB06457
small molecule | CAS: 75970-99-9

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Histamine H1 receptorVoltage-gated inwardly rectifying potassium channel KCNH2
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Teceleukin DB15389
biotech | CAS: 136279-32-8

Teceleukin is under investigation in clinical trial NCT03610490 (Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Osteosarcoma, or Pancreatic Ductal Adenocarcinoma).

Kategori:
Amino Acids, Peptides, and ProteinsAnalgesicsAnalgesics, Non-Narcotic +12
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Tecemotide DB12568
biotech | CAS: 221214-84-2

Tecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung.

Kategori:
Amino Acids, Peptides, and ProteinsBiological ProductsCarbohydrates +6
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small molecule | CAS: 14133-76-7

Technetium-99m is the metastable isotope of technetium. It is commonly symbolized as 99mTc and used in the area of medical diagnosis. Technetium-99m is the most commonly used medical radioisotope.

Kategori:
ElementsElements, RadioactiveIsotopes +4
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biotech

Deskripsi belum tersedia.

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
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biotech | CAS: 154361-49-6

Reduced Fab fragment of the murine IgG1 monoclonal antibody IMMU-4 (also called NP-4) with specificity for carcinoembryonic antigen (CEA) covalently labeled with Technitium 99. The molecule has a molecular weight of ~54,000 Daltons.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +9
Target Protein:
Cell adhesion molecule CEACAM1
Waktu ParuhApproximately 1 hour
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small molecule | CAS: 374107-43-4

99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal abscess, pneumonia, appendi…

Kategori:
4-QuinolonesAnti-Bacterial AgentsCytochrome P-450 CYP1A2 Inhibitors +9
Target Protein:
DNA gyrase subunit BDNA topoisomerase 2-beta
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Technetium Tc-99m disofenin Approved DB09164
small molecule

Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bil…

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Peptides, and Proteins +15
Waktu ParuhTechnetium Tc99m de…
Vol. DistribusiTechnetium Tc99M di…
KlirensTechnetium Tc 99M D…
Genetik -
biotech

Technetium Tc-99m epratuzumab is under investigation in clinical trial NCT00003337 (Radiolabeled Monoclonal Antibody in the Detection and Staging of Patients With Non-Hodgkin's Lymphoma).

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Technetium Tc-99m etidronate Approved DB09411
small molecule | CAS: 63347-65-9

Deskripsi belum tersedia.

Kategori:
Compounds used in a research, industrial, or household settingDiagnostic RadiopharmaceuticalsDiagnostic Uses of Chemicals +6
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small molecule | CAS: 72950-39-1

Deskripsi belum tersedia.

Kategori:
Diagnostic RadiopharmaceuticalsHepatic and Reticulo Endothelial SystemTechnetium (99Mtc) Compounds
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small molecule | CAS: 99944-78-2

Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise…

Kategori:
AminesCentral Nervous SystemCompounds used in a research, industrial, or household setting +13
Waktu Paruh-
Vol. DistribusiThe activity not as…
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Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsLigandsOrganometallic Compounds +1
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Technetium Tc-99m mebrofenin Approved DB09137
small molecule | CAS: 1415247-71-0

Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver o…

Kategori:
AminesAmino AcidsAmino Acids, Peptides, and Proteins +14
Waktu ParuhTechnetium Tc 99m d…
Vol. Distribusi-
KlirensFollowing intraveno…
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Technetium Tc-99m medronate Approved DB09138
small molecule | CAS: 121524-79-6

Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medroni…

Kategori:
Compounds used in a research, industrial, or household settingDiagnostic RadiopharmaceuticalsDiagnostic Uses of Chemicals +11
Waktu ParuhTechnetium Tc-99m d…
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small molecule | CAS: 165942-79-0

Technetium Tc-99m nofetumomab merpentan (Tc-99m nm) consists of a Fab fragment of an IgG2b of the pancarcinoma murine antibody NR-LU-10.[A32115] The NR-LU-10 antibody is directed against a 40 kDa glycoprotein antigen expressed in a variety of cancers and some…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
Epithelial cell adhesion moleculeB-lymphocyte antigen CD20
Waktu ParuhThe radioactive hal…
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Technetium Tc-99m oxidronate Approved DB09139
small molecule | CAS: 72945-61-0

Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical agent. A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and/or therapy.…

Kategori:
Diagnostic RadiopharmaceuticalsDrugs that are Mainly Renally ExcretedOrganometallic Compounds +6
Waktu ParuhThe elimination of …
Vol. DistribusiThe distribution of…
KlirensDuring the first 24…
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small molecule | CAS: 23288-61-1

Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine…

Kategori:
Compounds used in a research, industrial, or household settingDiagnostic RadiopharmaceuticalsDiagnostic Uses of Chemicals +7
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small molecule

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAnions +6
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small molecule | CAS: 52997-54-3

A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloi…

Kategori:
AcidsAcids, NoncarboxylicCompounds used in a research, industrial, or household setting +17
Target Protein:
HydroxyapatiteAmorphous calcium phosphate
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biotech

Technetium Tc-99m red blood cells is a radiopharmaceutical diagnostic agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu ParuhTechnetium Tc 99m d…
Vol. DistribusiFollowing intraveno…
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Technetium Tc-99m sestamibi Approved DB09161
small molecule | CAS: 109581-73-9

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name…

Kategori:
Compounds used in a research, industrial, or household settingDiagnostic RadiopharmaceuticalsDiagnostic Uses of Chemicals +10
Waktu ParuhTechnetium Tc 99m d…
Vol. Distribusi-
KlirensThe effective half-…
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Technetium Tc-99m succimer Approved DB09436
small molecule | CAS: 65438-08-6

Technetium Tc-99m (<sup>99m</sup>Tc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA),[A245643] is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorder…

Kategori:
Acids, AcyclicCompounds used in a research, industrial, or household settingDiagnostic Radiopharmaceuticals +14
Waktu ParuhTechnetium Tc-99m d…
Vol. DistribusiThere is no informa…
KlirensThere is no informa…
Genetik -
small molecule

Technetium 99m sulfur colloid is a radiopharmaceutical diagnostic agent used in the evaluation of various conditions including lymph node metastases in breast cancer, detection of shunt patency, imaging of reticuloendothelial cells for assessment of liver fun…

Kategori:
Compounds used in a research, industrial, or household settingDiagnostic RadiopharmaceuticalsDiagnostic Uses of Chemicals +9
Waktu ParuhTechnetium Tc 99m d…
Vol. DistribusiFollowing oral inge…
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small molecule | CAS: 127455-27-0

Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to a…

Kategori:
Compounds used in a research, industrial, or household settingDiagnostic RadiopharmaceuticalsDiagnostic Uses of Chemicals +7
Waktu ParuhTechnetium-99m tetr…
Vol. DistribusiReports have shown …
KlirensTechnetium-99m tetr…
Genetik -
small molecule | CAS: 1262984-82-6

Technetium Tc-99m tilmanocept is a radiopharmaceutical diagnostic imaging agent approved by the U.S. Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging. It is a macromolecule consisting of multiple units of…

Kategori:
Diagnostic RadiopharmaceuticalsRadioactive Diagnostic AgentRadiopharmaceutical Activity +2
Target Protein:
Macrophage mannose receptor 1
Waktu ParuhTechnetium Tc99m ti…
Vol. Distribusi-
KlirensIn dose-ranging cli…
Genetik -
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