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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
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17430 (100.0%)

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Hasil Pencarian (17430)

Halaman 311 / 349
Surotomycin DB12076
small molecule | CAS: 1233389-51-9

Surotomycin has been used in trials studying the treatment of Diarrhea and Clostridium Difficile Infection. It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents for the treatment of Gram-positive infections.…

Kategori:
Amino Acids, Peptides, and ProteinsLipidsPeptides
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Surufatinib DB15106
small molecule | CAS: 1308672-74-3

Surufatinib is under investigation in clinical trial NCT02588170 (Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors).

Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +4
Target Protein:
Fibroblast growth factor receptor 1Vascular endothelial growth factor receptor 2Vascular endothelial growth factor receptor 3 +2
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SurVaxM DB17397
biotech | CAS: 2416847-76-0

Deskripsi belum tersedia.

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Survodutide DB18989
biotech | CAS: 2805997-46-8

Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)).

Kategori:
Amino Acids, Peptides, and Proteins
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Surzebiclimab DB16669
biotech | CAS: 2342597-90-2

Surzebiclimab is under investigation in clinical trial NCT03744468 (Study of BGB-A425 in Combination With Tislelizumab in Advanced Solid Tumors).

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Sus scrofa hair Approved DB10881
biotech

Wild boar hair is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Sus scrofa placenta is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Sus scrofa skin Approved DB10606
biotech

Sus scrofa skin or pelt is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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biotech

Deskripsi belum tersedia.

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Susoctocog alfa Approved DB11606
biotech | CAS: 1339940-90-7

Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare blee…

Kategori:
Blood and Blood Forming OrgansBlood Coagulation FactorsHemostatics
Target Protein:
von Willebrand factor
Waktu ParuhThe terminal half-l…
Vol. DistribusiFollowing intraveno…
KlirensFollowing intraveno…
Genetik -
Sutetinib DB18841
small molecule | CAS: 1259519-20-4

Sutetinib is under investigation in clinical trial NCT05168566 (Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer).

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Sutezolid DB11905
small molecule | CAS: 168828-58-8

Sutezolid has been used in trials studying the treatment of Tuberculosis.

Kategori:
AcetatesAcids, AcyclicAmides +2
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Sutilain Approved DB09379
biotech | CAS: 12211-28-8

Sutilain is a member of the keratase family which includes agents such as papain. It is able to dissolve the intercellular matrix which helps with desquamation. Sutilain contains proteolytic enzymes derived from _Bacillus subtilis_ and it is available as a cr…

Kategori:
EndopeptidasesEnzymesEnzymes and Coenzymes +4
Waktu ParuhThis pharmacokineti…
Vol. DistribusiThis pharmacokineti…
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Sutimlimab Approved DB14996
biotech | CAS: 2049079-64-1

Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +11
Target Protein:
Complement C1s subcomponent
Waktu ParuhAt the approved rec…
Vol. DistribusiAt steady-state, th…
KlirensAt the approved rec…
Genetik -
Suvecaltamide DB19139
small molecule | CAS: 953778-58-0

Suvecaltamide is under investigation in clinical trial NCT05122650 (A Study to Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)).

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SUVN-502 DB06140
small molecule | CAS: 701205-60-9

SUVN-502 is a novel, potent, safe, highly selective and orally active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of cognitive disorders such as Alzheimer’s and Schizophrenia, an unmet medical need.

Kategori:
Antidepressive AgentsCentral Nervous System DepressantsHeterocyclic Compounds, Fused-Ring +3
Target Protein:
5-hydroxytryptamine receptor 6
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SUVN-G3031 DB14835
small molecule | CAS: 1394808-82-2

SUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-G3031 in Healthy Subjects).

Kategori:
Oxazines
Target Protein:
Histamine H3 receptor
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Suvodirsen DB17940
biotech | CAS: 2095270-67-8

Suvodirsen is an antisense oligonucleotide that has been investigated for the treatment of Duchenne muscular dystrophy.

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Suvorexant Approved DB09034
small molecule | CAS: 1030377-33-3

Suvorexant is a selective dual antagonist of orexin receptors OX1R and OX2R that promotes sleep by reducing wakefulness and arousal. It has been approved for the treatment of insomnia.

Kategori:
Central Nervous System AgentsCentral Nervous System DepressantsCytochrome P-450 CYP3A Inhibitors +13
Target Protein:
Orexin/Hypocretin receptor type 1Orexin receptor type 2
Waktu ParuhMean half life is a…
Vol. DistribusiMean volume of dist…
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Suvratoxumab DB15172
biotech | CAS: 1629620-18-3

Suvratoxumab is under investigation in clinical trial NCT02296320 (Study of the Efficacy and Safety of MEDI4893).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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Suxibuzone DB13232
small molecule | CAS: 27470-51-5

Deskripsi belum tersedia.

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAnalgesics +13
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Suzetrigine DB18927
small molecule | CAS: 2649467-58-1

Suzetrigine is under investigation in clinical trial NCT05558410 (Evaluation of Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty).

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SVV-001 DB06129
biotech

SVV-001 is investigated for use/treatment in cancer/tumors and lung cancer. SVV-001 is a solid. SVV-001 (Seneca Valley Virus) is a novel native picornavirus being developed as a systemically deliverable oncolytic virus for treatment of human cancers with neur…

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Sweet cherry Approved DB10853
biotech

Sweet cherry allergenic extract is used in allergenic testing.

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Sweet potato Approved DB10648
biotech

Sweet potato allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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biotech

Swertia japonica whole flowering is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Swordfish Approved DB10625
biotech

Swordfish allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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SX-682 DB19210
small molecule | CAS: 1648843-04-2

SX-682 is under investigation in clinical trial NCT04574583 (Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With Bintrafusp Alfa (M7824 or Tgf-beta "Trap"/pd-l1) With CV301 TRIC…

Target Protein:
C-X-C chemokine receptor type 2C-X-C chemokine receptor type 1
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SXR-1096 DB18119
small molecule | CAS: 1087624-28-9

Deskripsi belum tersedia.

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SY-5609 DB17099
small molecule | CAS: 2417302-07-7

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
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Syagrus romanzoffiana pollen Approved DB10482
biotech

Syagrus romanzoffiana pollen is the pollen of the Syagrus romanzoffiana plant. Syagrus romanzoffiana pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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SYD-003 DB17106
small molecule | CAS: 249937-52-8

Deskripsi belum tersedia.

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small molecule | CAS: 30344-00-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +1
Target Protein:
Haloalkane dehalogenase
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SYN-101 DB05958
biotech

SYN-101 is an investigational antibody-drug conjugate developed for the treatment of cancer. SYN101 is comprised of an immune cell specific antibody linked to an ALK5 inhibitor payload to selectively block TGF-b signalling in immune cells.

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SYNB1020 DB17667
biotech

SYNB1020 is an engineered strain of _Escherichia coli_ Nissle 1917 developed by Synlogic Inc. It was initially designed to convert ammonia to L-arginine [A258838] and granted orphan designation by the FDA for the treatment of urea cycle disorders in August 20…

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SYNB1353 DB17666
biotech

SYNB1353 is a strain of the probiotic bacteria _Escherichia coli_ (_E. coli_) type Nissle and an engineered probiotic drug.[A258833] Developed by Synlogic Operating Company, Inc., SYNB1353 is being investigated for the treatment of homocystinuria. It is desig…

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SYNB1891 DB17541
biotech

SYNB1891 is a live, modified strain of the probiotic _Escherichia coli_ Nissle engineered to produce cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway.[A256733] SYNB1891 is under investigation in clinical trial NCT0416713…

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Syncephalastrum racemosum Approved DB10848
biotech

Syncephalastrum racemosum is a fungus which can provoke allergic reactions. Syncephalastrum racemosum extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Synephrine DB09203
small molecule | CAS: 94-07-5

Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-Agonists +23
Target Protein:
Alpha-1 adrenergic receptors
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SynKIR-110 DB17365
biotech

SynKIR-110 are autologous T cells genetically engineered to express an anti-mesothelin killer immunoglobulin-like receptor-chimeric antigen receptor (KIR-CAR).

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SynOV1.1 DB17539
biotech

SynOV1.1 is an investigational cancer immunotherapy developed by SyngenTech. It is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating factor cytokine granulocyte-macrophage colony-stimulating factor …

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Synthetic camphor Approved DB14156
small molecule | CAS: 76-22-2

Deskripsi belum tersedia.

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small molecule

Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances: estrone sulfate, sodium equilin sulfate, sodium 17?-dihydroequilin sulfate, sodium 17?-estradiol sulfate, sodium 17?­ dihydroequilin sulfate, sodiu…

Kategori:
Cytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 SubstratesCytochrome P-450 Substrates +7
Target Protein:
Estrogen receptor
Waktu ParuhThe half life of ba…
Vol. DistribusiThe distribution of…
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small molecule | CAS: 746658-13-9

Synthetic conjugated estrogens, B tablets contain a blend of ten synthetic estrogenic substances. The estrogenic substances are: sodium estrone sulfate, sodium equilin sulfate, sodium 17?-dihydroequilin sulfate, sodium 17?-estradiol sulfate, sodium 17?­ dihyd…

Kategori:
Cytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 SubstratesCytochrome P-450 Substrates +7
Target Protein:
Estrogen receptor
Waktu ParuhThe half life of ba…
Vol. DistribusiThe distribution of…
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SYRINGATE DB08589
small molecule

Deskripsi belum tersedia.

Target Protein:
Endo-1,4-beta-xylanase Y
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Syrosingopine Approved DB19379
small molecule | CAS: 84-36-6

Deskripsi belum tersedia.

Kategori:
AlkaloidsAntihypertensive AgentsHeterocyclic Compounds, Fused-Ring +5
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T-2000 DB11654
small molecule | CAS: 97846-21-4

T2000 has been used in trials studying the treatment of Myoclonus and Essential Tremor.

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T-5224 DB05998
small molecule | CAS: 530141-72-1

T-5224 is an investigational drug developed to treat Sepsis-induced Acute Kidney Injury. It's mechanism of action is to inhibit c-Fos/activator protein-1.

Kategori:
Benzene DerivativesKetones
Target Protein:
Transcription factor Jun
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T-62 DB12919
small molecule | CAS: 40312-34-3

T-62 has been used in trials studying the treatment of Postherpetic Neuralgia.

Target Protein:
Adenosine receptor A2a
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T-900607 DB12068
small molecule | CAS: 261944-52-9

T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.

Kategori:
AmidesSulfonesSulfur Compounds
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