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3253

Total database: 17430
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2451 (75.3%)
Target
1833 (56.3%)
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35 (1.1%)
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3253 (100.0%)

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Halaman 31 / 66
biotech

The SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus and is inactivated in Vero Cells[A219758]. This vaccine specifically was developed in collaboration with the Chinese Academy of Medical Sciences, West Chin…

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Inarigivir DB15062
small molecule | CAS: 475650-36-3

Inarigivir is under investigation in clinical trial NCT03434353 (Study to Evaluate the Antiviral Activity of Inarigivir (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB)).

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small molecule | CAS: 942123-43-5

Inarigivir soproxil is under investigation in clinical trial NCT03434353 (Study to Evaluate the Antiviral Activity of Inarigivir (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB)).

Target Protein:
Nucleotide-binding oligomerization domain-containing protein 2
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Incadronic acid DB06255
small molecule | CAS: 124351-85-5

Incadronate, or YM-175,[A202769] is a nitrogen containing bisphosphonate. Along with being investigated to treat hypercalcemia of malignancy,[A202862] it has also been investigated in the treatment of myeloma, leukemia, and other cancers.[A14426,A14431,A14427…

Kategori:
Antineoplastic AgentsBisphosphonatesBone Density Conservation Agents +2
Target Protein:
Farnesyl pyrophosphate synthaseCaspase-3Caspase-4 +1
Waktu ParuhIncadronate has a b…
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INCB-9471 DB12960
small molecule | CAS: 869769-98-2

INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat HIV/AIDS. It is a potent, selective inhibitor of the HIV-1 virus.

Kategori:
Receptors, CCR4, antagonists & inhibitors
Target Protein:
C-C chemokine receptor type 5
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Inclacumab DB12246
biotech | CAS: 1256258-86-2

Inclacumab has been used in trials studying the treatment and prevention of Myocardial Infarction, Peripheral Arterial Disease (PAD), and Coronary Heart Disease, Graft Occlusion, Vascular.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
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Indacaterol Approved DB05039
small molecule | CAS: 312753-06-3

Indacaterol is a novel, ultra-long-acting, rapid onset ?(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 20…

Kategori:
Adrenergic AgonistsAdrenergic beta-2 Receptor AgonistsAdrenergic beta-Agonists +17
Target Protein:
Beta-2 adrenergic receptor
Waktu ParuhIndacaterol serum c…
Vol. DistribusiAfter intravenous i…
KlirensRenal clearance of …
Genetik -
Indantadol DB12664
small molecule | CAS: 202844-10-8

Indantadol has been used in trials studying the treatment of Cough and Diabetic Peripheral Neuropathic Pain.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsIndenes +1
Target Protein:
Amine oxidase [flavin-containing] BAmine oxidase [flavin-containing] A
Waktu Paruh-
Vol. Distribusi-
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biotech | CAS: 1238517-16-2

Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Bacterial AgentsAntibodies +10
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Indiplon DB12590
small molecule | CAS: 325715-02-4

Indiplon has been used in trials studying the treatment of Insomnia and Depression.

Kategori:
BenzazepinesCentral Nervous System AgentsCentral Nervous System Depressants +7
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1
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Indirubin DB12379
small molecule | CAS: 479-41-4

Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).

Kategori:
Antibiotics, AntineoplasticAntineoplastic AgentsColoring Agents +4
Target Protein:
Cytochrome P450 1A1Aryl hydrocarbon receptor
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Indobufen DB12545
small molecule | CAS: 63610-08-2

Indobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +16
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Indole DB04532
small molecule | CAS: 120-72-9

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
EndolysinNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
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small molecule | CAS: 700-06-1

Indole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).

Kategori:
Anticarcinogenic AgentsAntineoplastic AgentsCompounds used in a research, industrial, or household setting +2
Target Protein:
NF-kappa-B inhibitor alpha
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Indoramin Approved DB08950
small molecule | CAS: 26844-12-2

Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.

Kategori:
Acids, CarbocyclicAdrenergic AgentsAdrenergic alpha-1 Receptor Antagonists +16
Target Protein:
Alpha-1D adrenergic receptorAlpha-2C adrenergic receptorAlpha-2B adrenergic receptor +1
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Indotecan DB18752
small molecule | CAS: 915303-09-2

Deskripsi belum tersedia.

Kategori:
DioxolesDNA Topoisomerases, Type IHeterocyclic Compounds, Fused-Ring
Target Protein:
DNA topoisomerase 1
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Indoximod DB12827
small molecule | CAS: 110117-83-4

Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +2
Target Protein:
Indoleamine 2,3-dioxygenase 1
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biotech | CAS: 1514889-12-3

Indusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and Advanced Gastrointestinal Carcinoma, among others.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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Inebilizumab Approved DB12530
biotech | CAS: 1299440-37-1

Inappropriate growth of or self-directed antibody production by B-cells is the etiological underpinning of a variety of conditions, including the multiple sclerosis-like neurological condition neuromyelitis optica spectrum disorder (NMOSD).[A214283, A214286] …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +12
Target Protein:
B-lymphocyte antigen CD19
Waktu ParuhInebilizumab exhibi…
Vol. DistribusiInebilizumab has an…
KlirensInebilizumab has an…
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune…

Kategori:
Inactivated Influenza A Virus VaccineInfluenza VaccinesVaccines +1
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biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune…

Kategori:
Inactivated Influenza A Virus VaccineInfluenza VaccinesVaccines +1
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biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1383547-60-1

Ingenol disoxate is under investigation in clinical trial NCT02120456 (Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis).

Kategori:
Terpenes
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Ingenol mebutate Approved DB05013
small molecule | CAS: 75567-37-2

Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis. Before approval, ingenol mebutate was called PEP005 as an investigational drug. PEP005…

Kategori:
Cell Death InducerDermatologicalsIncreased Cellular Death +2
Target Protein:
Protein kinase C delta typeProtein kinase C alpha type
Waktu ParuhThere is no half-li…
Vol. DistribusiThere is no volume …
KlirensThere is no clearan…
Genetik -
Insulin aspart Approved DB01306
biotech | CAS: 116094-23-6

Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin…

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsBlood Glucose Lowering Agents +14
Target Protein:
Insulin receptorInsulin-like growth factor 1 receptor
Waktu ParuhElimination half-li…
Vol. Distribusi-
Klirens1.2 L/h/kg
Genetik -
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