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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Hasil Pencarian (17430)

Halaman 302 / 349
SLN500 DB18636
biotech

SLN500 is a synthetic double-strand small interfering ribonucleic acid (siRNA) oligonucleotide drug directed against C3 messenger RNA

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SLV-334 DB15356
small molecule | CAS: 182821-33-6

SLV-334 is under investigation in clinical trial NCT00735085 (A Phase 2a Dose Escalation Study With SLV334 in Patients With Traumatic Brain Injury.).

Target Protein:
Neprilysin
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SLV319 DB05077
small molecule

SLV319 belongs to a novel class of agents called CB1 antagonists, which work by blocking the cannabinoid type 1 (CB1) receptor. It is developed for the treatment of obesity and other metabolic disorders.

Kategori:
Agents producing tachycardiaAmidesCannabinoid Receptor Antagonists +4
Target Protein:
Cannabinoid receptor 1
Waktu Paruh-
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SLx-2101 DB05615
small molecule

SLx-2101 is an oral, long-acting PDE5 inhibitor developed by Surface Logix Inc. to treat Hypertension.

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SLx-4090 DB05678
small molecule | CAS: 913541-47-6

SLx-4090 is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes. [A33218]

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
Target Protein:
Microsomal triglyceride transfer protein large subunit
Waktu Paruh-
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SM-1997 DB18670
biotech

SM-1997 is a protein-free solution derived from calf's blood comprising electrolytes, trace minerals, amino acids, peptides, nucleosides, and nucleotides.[A261816] It is under investigation for the treatment of cutaneous sulfur mustard-induced injury.

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SM-337 DB17112
small molecule | CAS: 1071992-61-4

Deskripsi belum tersedia.

Target Protein:
E3 ubiquitin-protein ligase XIAP
Waktu Paruh-
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Genetik -
biotech

The New York City Board of Health strain of _Vaccinia_ is a viral strain used as a component of some smallpox vaccinations.[L12747] ACAM2000, a percutaneously administered smallpox vaccine that was approved by the FDA in 2007, contains live antigens of this s…

Kategori:
Actively Acquired ImmunityBiological ProductsComplex Mixtures +4
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Genetik -
biotech

Deskripsi belum tersedia.

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SMART101 DB18370
biotech

SMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors that were cultured ex vivo.

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Smelt Approved DB10624
biotech

Smelt allergenic extract is used in allergenic testing.

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Smilagenin DB05450
small molecule | CAS: 126-18-1

Smilagenin is a novel non-peptide, orally bioavailable neurotrophic factor inducer that readily reverses free radical neurotoxicity produced by 1-ethyl-4- phenylpyridium (MPP+) in dopaminergic neurones and reverses the decrease of neuronal growth factors and …

Kategori:
CholestanesDrugs, Chinese HerbalFused-Ring Compounds +4
Waktu Paruh-
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SN-38 DB05482
small molecule | CAS: 86639-52-3

7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of …

Kategori:
AlkaloidsAntineoplastic AgentsCytochrome P-450 CYP3A Inhibitors +9
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
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small molecule | CAS: 59734-15-5

Deskripsi belum tersedia.

Kategori:
GlycerophosphatesGlycerophospholipidsLipids +3
Target Protein:
Annexin A5
Waktu Paruh-
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small molecule | CAS: 17989-41-2

Deskripsi belum tersedia.

Target Protein:
Fructose-bisphosphate aldolase BPyridoxine 5'-phosphate synthaseTriosephosphate isomerase +1
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Snail, unspecified Approved DB14245
biotech

Snail, unspecified is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

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SNP-ACTH (1-39) DB18544
biotech

SNP-ACTH (1-39) is a synthetic porcine Corticotropin (ACTH)

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SNS-032 DB05969
small molecule | CAS: 345627-80-7

Deskripsi belum tersedia.

Kategori:
Sulfur Compounds
Target Protein:
Cyclin-dependent kinase 9Cyclin-dependent kinase 2Cyclin-dependent kinase 7 +1
Waktu Paruh-
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SNS-314 DB06134
small molecule | CAS: 1057249-41-8

SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis, leading to multiple rounds of endoreduplication and eventually cell deat…

Kategori:
AmidesBenzene DerivativesProtein Kinase Inhibitors +1
Target Protein:
Aurora kinase BAurora kinase CAurora kinase A
Waktu Paruh-
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SNS01-T DB17302
biotech

SNS01-T is a gene therapy nanoparticle. It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets the native eIF5A that promotes growth/anti-apoptosis of cancer cells; and polyethylenimine.[A254706]

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SNSP113 DB17910
small molecule

Deskripsi belum tersedia.

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small molecule | CAS: 1226795-18-1

Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F)).

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SNX-2112 DB17055
small molecule | CAS: 908112-43-6

SNX-2112 is a heat shock protein 90 (Hsp90) inhibitor.[A253137]

Kategori:
Heterocyclic Compounds, Fused-RingHSP90 Heat-Shock Proteins, antagonists & inhibitors
Target Protein:
Heat shock protein HSP 90-alpha
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SNX-5422 DB06070
small molecule | CAS: 908115-27-5

SNX-5422 is a synthetic, novel, small molecule Hsp90 Inhibitor. As an oral formulation that demonstrates strong efficacy and tolerability, SNX-5422 is positioned as a breakthrough therapy with broad applicability across a wide range of cancers.

Kategori:
Acids, CarbocyclicAmidesAmino Acids +5
Target Protein:
Heat shock protein HSP 90-alphaHeat shock protein HSP 90-beta
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SO-101 DB05345
small molecule

SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia. Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 7…

Target Protein:
Histamine H1 receptor
Waktu Paruh-
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Sobetirome DB07425
small molecule | CAS: 211110-63-3

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicBenzene DerivativesFatty Acids +2
Target Protein:
Muscarinic acetylcholine receptor M1Thyroid hormone receptor, alpha isoform 1 variantThyroid hormone receptor beta
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SOBI-003 DB15451
biotech

SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients).

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Soblidotin DB12677
small molecule | CAS: 149606-27-9

Soblidotin has been used in trials studying the treatment of Sarcoma, Lung Cancer, and Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic AgentsPeptides
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Sobrerol DB13315
small molecule | CAS: 42370-41-2

Deskripsi belum tersedia.

Kategori:
Cough and Cold PreparationsExpectorantsRespiratory System Agents
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Socazolimab DB18845
biotech | CAS: 2305043-30-3

Socazolimab is under investigation in clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody) in Patients With ES-SCLC).

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Sodelglitazar DB16332
small molecule | CAS: 447406-78-2

Sodelglitazar is under investigation in clinical trial NCT00196989 (Study in People With Type 2 Diabetes).

Target Protein:
Peroxisome proliferator-activated receptor deltaPeroxisome proliferator-activated receptor gammaPeroxisome proliferator-activated receptor alpha
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small molecule | CAS: 200880-41-7

Deskripsi belum tersedia.

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Sodium acetate Approved DB09395
small molecule | CAS: 127-09-3

Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important compo…

Kategori:
AcetatesAcids, AcyclicBlood and Blood Forming Organs +5
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small molecule | CAS: 1344-00-9

Deskripsi belum tersedia.

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Sodium apolate DB13477
small molecule | CAS: 25053-27-4

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAlkenes +12
Waktu Paruh-
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Sodium arsenite DB18508
small molecule | CAS: 7784-46-5

Deskripsi belum tersedia.

Kategori:
AnionsArsenicalsElectrolytes +3
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Sodium ascorbate Approved DB14482
small molecule | CAS: 134-03-2

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAntioxidantsBiological Factors +13
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Sodium aurothiomalate Approved DB09276
small molecule | CAS: 12244-57-4

Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. It is most effective in act…

Kategori:
Acids, AcyclicAntiinflammatory and Antirheumatic ProductsAntirheumatic Agents +13
Waktu Paruh12.5 days
Vol. DistribusiThe apparent volume…
Klirens7.0 ml/ kg/day
Genetik -
Sodium aurotiosulfate Approved DB13743
small molecule | CAS: 33614-49-2

Deskripsi belum tersedia.

Kategori:
Antiinflammatory and Antirheumatic ProductsGold PreparationsLaxatives +2
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Sodium bicarbonate Approved DB01390
small molecule | CAS: 144-55-8

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Kategori:
AntacidsAntacids and AdsorbentsBicarbonates +13
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1HA-type voltage-gated potassium channel KCND3Hydrogen ions
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Sodium bisulfite Approved DB14015
small molecule | CAS: 7631-90-5

Sodium bisulfite has been used externally for parasitic skin diseases and as a gastrointestinal antiseptic.

Kategori:
AnionsAnti-Infective AgentsAnti-Infective Agents, Local +10
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Sodium borate Approved DB14505
small molecule | CAS: 1330-43-4

Deskripsi belum tersedia.

Kategori:
AnionsAnti-Infective AgentsBoric Acids +5
Waktu ParuhAccording to human …
Vol. DistribusiVolume of distribut…
KlirensA case report of ac…
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Sodium camphorsulfonate Approved DB15950
small molecule | CAS: 21791-94-6

Deskripsi belum tersedia.

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Sodium carbonate Approved DB09460
small molecule | CAS: 497-19-8

Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid.

Kategori:
AlkaliesAnionsCarbon Compounds, Inorganic +3
Target Protein:
Carbonic anhydrase 1Carbonic anhydrase 2Carbonic anhydrase 4 +1
Waktu Paruh-
Vol. DistribusiDistribution occurs…
Klirens-
Genetik -
Sodium cation DB14516
small molecule | CAS: 17341-25-2

Deskripsi belum tersedia.

Kategori:
Increased Large Intestinal MotilityInhibition Large Intestine Fluid/Electrolyte AbsorptionLaxatives +2
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Sodium cellulose phosphate Approved DB06776
small molecule | CAS: 9038-41-9

Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. [A31694] This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intesti…

Kategori:
BiopolymersCalcium BinderCalcium Chelating Activity +8
Target Protein:
Calcium ions
Waktu Paruh-
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Sodium chloride Approved DB09153
small molecule | CAS: 7647-14-5

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid o…

Kategori:
Alimentary Tract and MetabolismBlood and Blood Forming OrgansBlood Substitutes and Perfusion Solutions +14
Waktu Paruh17 minutes
Vol. DistribusiThe volume of distr…
Klirens-
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Sodium chlorite DB13210
small molecule | CAS: 7758-19-2

Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, …

Kategori:
AnionsChlorine CompoundsCicatrizants +4
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Sodium chromate Cr-51 Approved DB09380
small molecule | CAS: 10039-53-9

Deskripsi belum tersedia.

Kategori:
Radioactive Diagnostic Agent
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Sodium citrate Approved DB09154
small molecule | CAS: 68-04-2

Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the me…

Kategori:
Acids, AcyclicAntacids and AdsorbentsAnticoagulants +21
Target Protein:
Carbonic anhydrase 4
Waktu Paruh18-54 min [A19414]
Vol. Distribusi19-39L [A19414].
KlirensTotal clearance of …
Genetik -
Menampilkan 15051–15100 dari 17430
Sebelumnya Halaman 302 / 349 Berikutnya