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6694

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4518 (67.5%)
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3751 (56.0%)
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81 (1.2%)
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6694 (100.0%)

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Halaman 30 / 134
Bleomycin A2 DB19091
small molecule | CAS: 11116-31-7

Bleomycin A2 is under investigation in clinical trial NCT00026208 (Combination Chemotherapy Plus Low-dose Radiation Therapy in Treating Patients With Stage I or Stage IIA Hodgkin's Lymphoma).

Kategori:
Amino Acids, Peptides, and ProteinsAngiogenesis InhibitorsAngiogenesis Modulating Agents +8
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Bleomycin A6 DB12992
small molecule | CAS: 37293-17-7

Bleomycin A6 (also known as boanmycin) has been used in trials studying the treatment of Squamous Cell Lung Cancer. It was developed in China as an antineoplastic antibiotic. This drug participated in clinical trials for the treatment of Squamous Cell Lung Ca…

Kategori:
Amino Acids, Peptides, and ProteinsCarbohydratesGlycoconjugates +2
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Bleselumab DB15253
biotech | CAS: 1453067-91-8

Bleselumab is under investigation in clinical trial NCT02921789 (Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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Bleximenib DB19328
small molecule | CAS: 2654081-35-1

Bleximenib is under investigation in clinical trials NCT04811560 (A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia) and NCT05453903 (A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies)

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Blinatumomab Approved DB09052
biotech | CAS: 853426-35-4

Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an ant…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +17
Target Protein:
B-lymphocyte antigen CD19T-cell surface glycoprotein CD3 delta chain
Waktu ParuhBlinatumomab has a …
Vol. DistribusiBlinatumomab has a …
KlirensBlinatumomab has an…
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Blonanserin DB09223
small molecule | CAS: 132810-10-7

Blonanserin is an atypical antipsychotic approved in Japan in January, 2008. It offers improved tolerability as it lacks side effects such as extrapyramidal symptoms, excessive sedation, or hypotension. As a second-generation (atypical) antipsychotic, it is s…

Kategori:
Antidepressive AgentsAntipsychotic AgentsAntipsychotic Agents (Second Generation [Atypical]) +13
Target Protein:
D(2) dopamine receptorD(3) dopamine receptor5-hydroxytryptamine receptor 2A
Waktu ParuhBlonanserin has a h…
Vol. DistribusiBlonanserin has a V…
KlirensBlonanserin has a c…
Genetik -
Blosozumab DB12560
biotech | CAS: 1132758-87-2

Blosozumab has been used in trials studying the basic science and treatment of Osteoporosis and Osteoporosis, Postmenopausal.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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BMS-181156 DB02466
small molecule | CAS: 110368-35-9

Deskripsi belum tersedia.

Target Protein:
Retinoic acid receptor gamma
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BMS-184476 DB12633
small molecule | CAS: 160237-25-2

BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
CyclodecanesCycloparaffinsDiterpenes +1
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BMS-188797 DB12619
small molecule | CAS: 172481-83-3

BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
CyclodecanesCycloparaffinsDiterpenes +1
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BMS-599626 DB12318
small molecule | CAS: 714971-09-2

BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.

Kategori:
Acids, AcyclicErbB Receptors, antagonists & inhibitors
Target Protein:
Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2
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BMS-777607 DB12064
small molecule | CAS: 1025720-94-8

BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.

Kategori:
AminesPyridines
Target Protein:
Hepatocyte growth factor receptor
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BMS-813160 DB16240
small molecule | CAS: 1286279-29-5

BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).

Kategori:
Cardiovascular Agents
Target Protein:
C-C chemokine receptor type 2C-C chemokine receptor type 5
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BMS-986141 DB14942
small molecule | CAS: 1478711-48-6

BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Target Protein:
PRKC apoptosis WT1 regulator protein
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BMS-986251 DB19007
small molecule | CAS: 2041841-30-7

BMS-986251 is under investigation in clinical trial NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis).

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BMS-986278 DB18011
small molecule | CAS: 2170126-74-4

Deskripsi belum tersedia.

Target Protein:
Lysophosphatidic acid receptor 1
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BN-201 DB18295
small molecule | CAS: 1361200-34-1

Deskripsi belum tersedia.

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biotech

BN?Brachyury vaccine is a novel prime?boost therapeutic cancer immunotherapy. It is composed of the [MVA-BN-brachyury-TRICOM vaccine] and the fowlpox virus(FPV)?Brachyury booster vaccine.[A255173]

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BNT-162A1 DB16402
biotech | CAS: 2417899-74-0

BNT-162A1 is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +10
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BNT111 DB18177
biotech

BNT111 is an investigational cancer immunotherapy under development for advanced melanoma. It consists of a fixed combination of mRNA-encoded, tumor-associated antigens.

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biotech

BNT162a1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162a1 is a uridine mRNA (uRNA) vaccine formulated in lipid nanoparticles for delivery via intram…

Kategori:
Experimental Unapproved Treatments for COVID-19
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biotech

BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) …

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +11
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BNT162b2 Omicron (KP.2) Approved DB19415
biotech

BNT162b2 Omicron (KP.2) is COVID-19 mRNA vaccine encoding the viral spike (S) glycoprotein of SARS-CoV-2 Omicron variant lineage KP.2. It is the active ingredient in the 2024-2025 formulation of Pfizer-BioNTech's Comirnaty vaccine.[L36030]

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BNT162b3 DB16442
biotech

The BNT162b3 vaccine is the latest addition to BioNTech and partner Pfizer’s mRNA COVID-19 vaccine program. Similar to [BNT162b2], BNT162b3 uses a nucleoside-modified RNA (modRNA) technology. Pfizer and BioNTech deemed this compound as promising in preclinica…

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biotech

BNT162c2 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162c2 is a self-amplifying mRNA (saRNA) vaccine formulated in lipid nanoparticles for delivery v…

Kategori:
Experimental Unapproved Treatments for COVID-19
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Boceprevir Approved DB08873
small molecule | CAS: 394730-60-0

Boceprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine…

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Peptides, and Proteins +21
Target Protein:
Genome polyproteinGenome polyprotein
Waktu ParuhBoceprevir has a me…
Vol. DistribusiThe mean apparent v…
KlirensBoceprevir has a me…
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Bocidelpar DB16906
small molecule | CAS: 2095128-20-2

Deskripsi belum tersedia.

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Bococizumab DB12456
biotech | CAS: 1407495-02-6

Bococizumab has been used in trials studying the treatment and prevention of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, and Heterozygous Familial Hypercholesterolemia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +11
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Borage oil Approved DB11238
biotech

Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as an herbal treatment of skin disorders including eczema, seborrheic dermatitis, and neurode…

Kategori:
Agents that reduce seizure thresholdAntirheumatic AgentsBiological Products +11
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biotech

Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) is a vaccine that contains inactivated acellular pertussis antigen that is isolated from Bordetella pertussis culture.

Kategori:
Actively Acquired ImmunityInactivated Bordetella Pertussis Vaccine
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biotech

Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct fimbriae (Fim2 and Fim3).

Kategori:
Actively Acquired ImmunityInactivated Bordetella Pertussis Vaccine
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biotech

Bordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis [A31248].

Kategori:
Amino Acids, Peptides, and ProteinsBacterial ProteinsBacterial Toxins +7
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biotech

Bordetella pertussis toxoid antigen (formaldehyde inactivated) is a vaccine.

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biotech

Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects the mucosal layers of the human resp…

Kategori:
Actively Acquired ImmunityBiological ProductsComplex Mixtures +2
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Boric acid Approved DB11326
small molecule | CAS: 10043-35-3

Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmet…

Kategori:
AcidsAcids, NoncarboxylicAgrochemicals +12
Waktu ParuhAccording to human …
Vol. DistribusiVolume of distribut…
KlirensA case report of ac…
Genetik -
Boron DB11203
small molecule | CAS: 7440-42-8

Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however …

Kategori:
Diet, Food, and NutritionElementsFood +4
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Bortezomib Approved DB00188
small molecule | CAS: 179324-69-7

Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma.[A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reve…

Kategori:
AcidsAcids, NoncarboxylicAntineoplastic Agents +36
Target Protein:
Proteasome subunit beta type-5Serine protease 1Proteasome subunit beta type-1
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe mean distributi…
KlirensFollowing the admin…
Genetik -
biotech

Bos taurus gallstone is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Complex MixturesGallstones
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Bosutinib Approved DB06616
small molecule | CAS: 380843-75-4

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hall…

Kategori:
AminesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +22
Target Protein:
Tyrosine-protein kinase ABL1Tyrosine-protein kinase LynProto-oncogene tyrosine-protein kinase Src +8
Waktu ParuhThe mean (SD) bosut…
Vol. DistribusiThe mean (SD) appar…
KlirensThe mean (SD) appar…
Genetik -
biotech | CAS: 2417551-39-2

Deskripsi belum tersedia.

Kategori:
Adeno-associated Viral Vector Therapies
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Botrytis cinerea Approved DB10428
biotech

Botrytis cinerea is a fungus which can provoke allergic reactions. Botrytis cinerea extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Botulinum toxin type A Approved DB00083
biotech | CAS: 93384-43-1

In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use.[A231824] With a wide variety of applications and favourable safety profile, Botulinum toxin A injecti…

Kategori:
Acetylcholine Release InhibitorsAgents that produce neuromuscular block (indirect)Amino Acids, Peptides, and Proteins +29
Target Protein:
Synaptosomal-associated protein 25Rho-related GTP-binding protein RhoB
Waktu ParuhThere is no readily…
Vol. DistribusiThere are extremely…
KlirensClearance informati…
Genetik -
Botulinum toxin type B Approved DB00042
biotech | CAS: 93384-44-2

Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and …

Kategori:
Acetylcholine Release InhibitorsAgents that produce neuromuscular block (indirect)Amino Acids, Peptides, and Proteins +28
Target Protein:
Vesicle-associated membrane protein 2Vesicle-associated membrane protein 1Synaptotagmin-2
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biotech

Botulinum toxin type e is under investigation in clinical trial NCT03193593 (Study to Evaluate EB-001 in Reducing Musculoskeletal Pain).

Kategori:
Amino Acids, Peptides, and ProteinsBacterial ProteinsBacterial Toxins +13
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Bouteloua gracilis pollen Approved DB10715
biotech

Bouteloua gracilis pollen is the pollen of the Bouteloua gracilis plant. Bouteloua gracilis pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityGrass Pollen Allergen ExtractsIncreased Histamine Release +2
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BPC-157 DB11882
small molecule | CAS: 137525-51-0

Bepecin is under investigation in clinical trial NCT02637284 (PCO-02 - Safety and Pharmacokinetics Trial).

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Ulcer AgentsGastrointestinal Agents +1
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BPH-608 DB07404
small molecule

Deskripsi belum tersedia.

Target Protein:
Farnesyl pyrophosphate synthaseDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)
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BQ-123 DB12054
small molecule | CAS: 136553-81-6

BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.

Kategori:
Amino Acids, Peptides, and ProteinsAntihypertensive AgentsCardiovascular Agents +2
Target Protein:
Endothelin-1 receptor
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BQ-788 DB17984
small molecule | CAS: 156161-89-6

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntihypertensive AgentsCardiovascular Agents +3
Target Protein:
Endothelin receptor type B
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Bradykinin DB12126
small molecule | CAS: 58-82-2

Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.

Kategori:
Amino Acids, Peptides, and ProteinsAutacoidsBiological Factors +11
Target Protein:
B2 bradykinin receptor
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Menampilkan 1451–1500 dari 6694
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