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807

Total database: 17430
Struktur (SMILES)
608 (75.3%)
Target
525 (65.1%)
Genomik
15 (1.9%)
Referensi
807 (100.0%)

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Hasil Pencarian (807)

Halaman 3 / 17
biotech | CAS: 472960-22-8

Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to imp…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alclometasone Approved DB00240
small molecule | CAS: 67452-97-5

Alclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsCorticosteroid Hormone Receptor Agonists +17
Target Protein:
Corticosteroid-binding globulinGlucocorticoid receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alfacalcidol Approved DB01436
small molecule | CAS: 41294-56-8

Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D].[A234044] It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxyla…

Kategori:
Alimentary Tract and MetabolismBone Density Conservation AgentsCholestanes +13
Target Protein:
Vitamin D3 receptor25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialRetinoic acid receptor RXR-alpha
Waktu ParuhThe half-life of al…
Vol. Distribusi-
Klirens-
Genetik -
Alfaxalone DB11371
small molecule | CAS: 23930-19-0

Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. Along with alfadolone, it is also one of the…

Kategori:
AnestheticsAnesthetics, GeneralCentral Nervous System Agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alfuzosin Approved DB00346
small molecule | CAS: 81403-80-7

Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their …

Kategori:
Adrenergic AgentsAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists +17
Target Protein:
Alpha-1 adrenergic receptorsAlpha-1A adrenergic receptorAlpha-1B adrenergic receptor +1
Waktu ParuhThe apparent elimin…
Vol. DistribusiThe volume of distr…
KlirensExercise caution if…
Genetik -
Algenpantucel-L DB17184
biotech

Deskripsi belum tersedia.

Kategori:
Biological ProductsComplex MixturesVaccines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Algestone DB18000
small molecule | CAS: 595-77-7

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesContraceptive Agents, FemaleContraceptive Agents, Hormonal +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24356-94-3

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesAlgestoneAnti-Inflammatory Agents +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alglucosidase alfa Approved DB01272
biotech | CAS: 420784-05-0

Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produc…

Kategori:
Alimentary Tract and MetabolismEnzymesEnzymes and Coenzymes +5
Target Protein:
Cation-dependent mannose-6-phosphate receptorGlycogen
Waktu Paruh2.3 ± 0.4 ho…
Vol. Distribusi* 96 ± 16 mL/kg [20…
Klirens* 25+/- 4 mL/hr/kg …
Genetik -
small molecule | CAS: 514-12-5

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 71018-10-5

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7292-42-4

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesAntineoplastic AgentsHeterocyclic Compounds, Fused-Ring +5
Target Protein:
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasePantothenate synthetaseNH(3)-dependent NAD(+) synthetase +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyproteinGag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alpha-1-proteinase inhibitor Approved DB00058
biotech | CAS: 9041-92-3

Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.

Kategori:
Acute-Phase ProteinsAlpha-GlobulinsAmino Acids, Peptides, and Proteins +21
Target Protein:
Neutrophil elastase
Waktu Paruh-
Vol. Distribusi* 5632 ± 2006 mL [A…
Klirens* 940 +/- 275 mL/da…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1
Target Protein:
Glycine amidinotransferase, mitochondrialGag-Pol polyproteinPro-epidermal growth factor +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
alpha-Amyl cinnamaldehyde Approved DB14175
small molecule | CAS: 122-40-7

alpha-Amyl cinnamaldehyde has a jasmine-like odor and is a widely used synthetic fragrance & suspected allergen. It is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleasePerfume +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
alpha-Arbutin Approved DB14109
small molecule | CAS: 84380-01-8

Deskripsi belum tersedia.

Target Protein:
Lysosomal alpha-glucosidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Prostatic acid phosphatase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
alpha-Carotene DB15909
small molecule | CAS: 7488-99-5

Deskripsi belum tersedia.

Kategori:
AlkenesBiological FactorsCyclohexanes +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 467428-30-4

Deskripsi belum tersedia.

Kategori:
Biological FactorsComplex MixturesMarine Toxins +3
Target Protein:
Neuronal acetylcholine receptor subunit alpha-10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 10016-20-3

Deskripsi belum tersedia.

Target Protein:
Cyclomaltodextrin glucanotransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 37388-49-1

Deskripsi belum tersedia.

Target Protein:
Ribokinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6189-71-5

Deskripsi belum tersedia.

Target Protein:
LactotransferrinL-arabinose-binding periplasmic protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 2255-14-3

Deskripsi belum tersedia.

Target Protein:
Beta-phosphoglucomutase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6294-16-2

The ?-anomer of D-galacturonic acid.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 58825-13-1

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, muscle form
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 10139-18-1

Deskripsi belum tersedia.

Target Protein:
Beta-phosphoglucomutasePhosphoglucomutase-1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15209-11-7

Deskripsi belum tersedia.

Target Protein:
Aldo-keto reductase family 1 member B1Glycogen phosphorylase, muscle formGlutamine--fructose-6-phosphate aminotransferase [isomerizing] +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 59-56-3

Deskripsi belum tersedia.

Kategori:
CarbohydratesHexosephosphatesSugar Phosphates
Target Protein:
Glycogen phosphorylase, muscle formPhosphomannomutase/phosphoglucomutaseMaltodextrin phosphorylase +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Vanadates
Target Protein:
Phosphoglucomutase-1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15978-07-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 40436-60-0

Deskripsi belum tersedia.

Target Protein:
Cation-dependent mannose-6-phosphate receptorPhosphomannomutase/phosphoglucomutaseCation-independent mannose-6-phosphate receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7658-08-4

The pyranose form of D-quinovose with an ?-configuration at the anomeric position .

Kategori:
CarbohydratesDeoxy Sugars
Target Protein:
Pancreatic alpha-amylaseCyclomaltodextrin glucanotransferaseAlpha-amylase +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Chondroitinase-BChondroitinase-ACExoglucanase/xylanase +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Citrate synthase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Alpha-hydroxy glycineamide (?HGA) is the active antiviral metabolite of tri-peptide glycyl-prolyl-glycine-amide (GPG-NH2). ?HGA inhibits the replication of HIV-1 in vitro by interfering with the capsid formation. It also has an effect on viral gp160 envelope …

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
AlcoholsFatty AlcoholsLipids +3
Target Protein:
Protein farnesyltransferase subunit betaProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 57818-44-7

alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study).

Kategori:
Fatty AcidsFatty Acids, EssentialFatty Acids, Omega-6 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1460-34-0

Deskripsi belum tersedia.

Kategori:
Pentanoic Acids
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24809-08-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 816-66-0

Deskripsi belum tersedia.

Kategori:
Caproates
Target Protein:
Deacetoxycephalosporin C synthaseD-2-hydroxyisocaproate dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 759-05-7

Deskripsi belum tersedia.

Kategori:
Pentanoic AcidsTerpenes
Target Protein:
Branched-chain-amino-acid aminotransferase, mitochondrial3-methyl-2-oxobutanoate hydroxymethyltransferaseDeacetoxycephalosporin C synthase +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
L-arabinose-binding periplasmic proteinArabinose operon regulatory proteinAldose 1-epimerase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
alpha-L-fucose DB04473
small molecule | CAS: 6696-41-9

Deskripsi belum tersedia.

Target Protein:
Genome polyproteinEnvelope glycoprotein gp160Immunoglobulin heavy constant gamma 1 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 71031-08-8

Deskripsi belum tersedia.

Target Protein:
Chondroitinase-AC
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 14687-15-1

Deskripsi belum tersedia.

Target Protein:
Mannose-binding protein CChondroitinase-AC
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 9051-29-0

alpha-Lactalbumin is under investigation in clinical trial NCT02082418 (Effects of Alpha-lactalbumin Intake on Metabolic and Cognitive Functions in Elderly).

Kategori:
AlbuminsAmino Acids, Peptides, and ProteinsAnimal Proteins, Dietary +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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