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17430

Total database: 17430
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12313 (70.6%)
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9368 (53.7%)
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17430 (100.0%)

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Halaman 297 / 349
Scallop Approved DB10623
biotech

Scallop allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Scarlet red Approved DB19136
small molecule | CAS: 85-83-6

Scarlet red is under investigation in clinical trial NCT00591916 (New Treatment for Donor Sites).

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household setting
Waktu Paruh-
Vol. Distribusi-
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Genetik -
SCB-2019 DB15805
biotech

SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The vaccine was developed and test…

Kategori:
Biological ProductsComplex MixturesVaccines +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
SCH-486757 DB12782
small molecule | CAS: 524019-25-8

Sch 486757 has been used in trials studying the treatment of Cough.

Kategori:
Aza Compounds
Waktu Paruh-
Vol. Distribusi-
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Genetik -
SCH-58500 DB17416
biotech

SCH-58500 is a recombinant replication-deficient adenovirus vector carrying the human p53 gene.

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Genetik -
SCH-900271 DB12433
small molecule | CAS: 915210-50-3

Sch 900271 has been used in trials studying the treatment of Mixed Hyperlipidemia and Primary Hypercholesterolemia.

Target Protein:
Hydroxycarboxylic acid receptor 2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Schinus molle pollen Approved DB10483
biotech

Schinus molle pollen is the pollen of the Schinus molle plant. Schinus molle pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
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SCIB1 DB18439
biotech

SCIB1 is an investigational cancer vaccine being developed by Scancell Ltd. It is being investigated for the treatment of melanoma. It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate the patient's T cell…

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Scopolamine Approved DB00747
small molecule | CAS: 51-34-3

Scopolamine is a tropane alkaloid isolated from members of the _Solanaceae_ family of plants, similar to [atropine] and [hyoscyamine], all of which structurally mimic the natural neurotransmitter [acetylcholine].[A228423, A228763] Scopolamine was first synthe…

Kategori:
AdjuvantsAdjuvants, AnesthesiaAgents producing tachycardia +30
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3 +5
Waktu ParuhThe half-life of sc…
Vol. DistribusiThe volume of distr…
KlirensIV infusion of 0.5 …
Genetik -
biotech

Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of *C. noxius*, *C. l. limpidus*, *C. l. tecomanus*, and *C. s. suffusus*. It is int…

Kategori:
AntiveninsPassively Acquired ImmunityVenom Neutralization
Waktu Paruh159 ± 57 h [FDA lab…
Vol. DistribusiSteady state: 13.6 …
Klirens83.5 ± 38.4 ml/Hr […
Genetik -
Scriptaid DB17053
small molecule | CAS: 287383-59-9

Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.[A253127]

Kategori:
AminesAntineoplastic AgentsEnzyme Inhibitors +2
Target Protein:
Histone deacetylase 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
AngiospermsBiological ProductsComplex Mixtures +10
Waktu Paruh-
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Scutellaria lateriflora Approved DB14339
biotech

Scutellaria lateriflora is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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SCY-635 DB12451
small molecule | CAS: 210759-10-7

SCY-635 has been investigated for the treatment of Chronic Hepatitis C and Hepatitis C Infection.

Kategori:
Amino Acids, Peptides, and ProteinsPeptidesPeptides, Cyclic
Target Protein:
Guided entry of tail-anchored proteins factor CAMLG
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
scyllo-inositol DB03106
small molecule | CAS: 488-59-5

An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phosph…

Kategori:
AlcoholsCarbohydratesStereoisomerism +1
Target Protein:
Lysosomal acid glucosylceramidase1-phosphatidylinositol phosphodiesteraseCDP-diacylglycerol--inositol 3-phosphatidyltransferase +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SD-0006 DB07943
small molecule | CAS: 271576-80-8

Deskripsi belum tersedia.

Target Protein:
Mitogen-activated protein kinase 14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SD118 DB05207
small molecule

SD118 was previously under investigation in Japan for a different indication and now, following re-profiling and evaluation in experimental animal models, has demonstrated its potential as a new oral therapy for neuropathic pain.

Target Protein:
Tumor necrosis factorInterleukin-1 receptor type 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SD146 DB02729
small molecule | CAS: 183854-21-9

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Selenium Compounds
Target Protein:
Nitric oxide synthase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sea salt Approved DB11266
small molecule

Sea salt is the salt obtained from the evaporation of seawater or water from saltwater lakes. Sea salt production is subject to little processing which leaves certain trace minerals and elements behind. In comparison, table salt is mined from underground sedi…

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Sea scallop Approved DB15538
biotech

Sea scallop allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SEA-BCMA DB18309
biotech | CAS: 2115084-53-0

Deskripsi belum tersedia.

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SEA-CD70 DB17555
biotech

SEA-CD70 is an investigational humanized, non-fucosylated monoclonal antibody targeting CD70. SEA-CD70 is under investigation in clinical trial NCT04227847 (A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies).

Waktu Paruh-
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Sebacic acid DB07645
small molecule | CAS: 111-20-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsLipids
Target Protein:
Hemoglobin subunit alphaHemoglobin subunit beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sebelipase alfa Approved DB11563
biotech | CAS: 1276027-63-4

The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage…

Kategori:
Alimentary Tract and MetabolismCarboxylic Ester HydrolasesCholesterol Ester Storage Disease, drug therapy +7
Waktu ParuhThe mean half-life …
Vol. DistribusiIn patients 4-11 ye…
KlirensAcross all age grou…
Genetik -
Sebetralstat DB18305
small molecule | CAS: 1933514-13-6

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
Secalciferol DB18406
small molecule | CAS: 55721-11-4

Deskripsi belum tersedia.

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Secale cereale pollen Approved DB10717
biotech

Secale cereale pollen is the pollen of the Secale cereale plant. Secale cereale pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityGrass Pollen Allergen ExtractsIncreased Histamine Release +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Seclidemstat DB17117
small molecule | CAS: 1423715-37-0

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +1
Target Protein:
Lysine-specific histone demethylase 1A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Secnidazole Approved DB12834
small molecule | CAS: 3366-95-8

Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays improved oral absorption and a longer terminal elimination half-life than other dru…

Kategori:
Anti-Infective AgentsAntibacterials for Systemic UseAntiinfectives for Systemic Use +18
Waktu ParuhThe plasma eliminat…
Vol. DistribusiThe apparent volume…
KlirensThe total body clea…
Genetik -
Secobarbital Approved DB00418
small molecule | CAS: 76-73-3

Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.

Kategori:
AdjuvantsAdjuvants, AnesthesiaAnticholinergic Agents +27
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-3Gamma-aminobutyric acid receptor subunit alpha-4 +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 29388-59-8

Secoisolariciresinol has been used in trials studying the prevention of Breast Cancer.

Kategori:
AlcoholsBenzene DerivativesBenzyl Compounds +5
Waktu Paruh-
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Klirens-
Genetik -
Secretin human Approved DB09532
biotech | CAS: 108153-74-8

Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 [L1875]. …

Kategori:
Amino Acids, Peptides, and ProteinsDiagnostic AgentsGastrointestinal Agents +11
Target Protein:
Secretin receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of sy…
Genetik -
Secretin porcine Approved DB09527
biotech | CAS: 17034-35-4

Secretin porcine stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma.

Kategori:
Gastrointestinal AgentsSecretin
Waktu Paruh-
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Secukinumab Approved DB09029
biotech | CAS: 1229022-83-6

Secukinumab is a fully human monoclonal IgG1/? antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis.[L39600] By blocking the actions of IL-17A, sec…

Kategori:
Agents reducing cytokine levelsAmino Acids, Peptides, and ProteinsAntibodies +14
Target Protein:
Interleukin-17A
Waktu ParuhThe half-life range…
Vol. DistribusiThe mean volume of …
KlirensThe mean systemic c…
Genetik -
Segesterone DB14584
small molecule | CAS: 7690-08-6

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesProgestins
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Segesterone acetate Approved DB14583
small molecule | CAS: 7759-35-5

Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 [A37048]. In animal studies, segesterone acetate was shown to be one of the most potent progestins [A37090]. It …

Kategori:
Adrenal Cortex HormonesContraceptive Agents, FemaleContraceptive Agents, Hormonal +24
Target Protein:
Progesterone receptorAndrogen receptorGlucocorticoid receptor
Waktu ParuhThe mean (SD) half …
Vol. DistribusiThe volume of distr…
KlirensNo pharmacokinetic …
Genetik -
SEL-24 DB18082
small molecule | CAS: 1616359-00-2

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
SEL-302 DB18434
biotech

SEL-302 is a recombinant adeno-associated virus vector-based gene therapy expressing the methylmalonyl-CoA mutase (MMUT) transgene.

Waktu Paruh-
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Genetik -
small molecule | CAS: 1609522-33-9

Deskripsi belum tersedia.

Target Protein:
Cyclin-dependent kinase 19Cyclin-dependent kinase 8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Seladelpar Approved DB12390
small molecule | CAS: 851528-79-5

Seladelpar is a peroxisome proliferator-activated receptor (PPAR)-delta (?) agonist. Seladelpar is a single enantiomer of the R-configuration.[L51149] On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary bili…

Kategori:
Acids, AcyclicAntimetabolitesBCRP/ABCG2 Substrates +13
Target Protein:
Peroxisome proliferator-activated receptor delta
Waktu ParuhFollowing administr…
Vol. DistribusiSeladelpar steady s…
KlirensThe apparent oral c…
Genetik -
Selamectin DB11459
small molecule | CAS: 220119-17-5

Selamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in dogs as well as prevent heartworms, fleas, ear mites, hookworms, and …

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiparasitic Agents +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Selatogrel DB15163
small molecule | CAS: 1159500-34-1

Selatogrel is under investigation in clinical trial NCT03814200 (A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects).

Kategori:
Organophosphorus Compounds
Target Protein:
P2Y purinoceptor 12
Waktu Paruh-
Vol. Distribusi-
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Selegiline Approved DB01037
small molecule | CAS: 14611-51-9

A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodop…

Kategori:
Agents that produce hypertensionAgents that reduce seizure thresholdAmines +42
Target Protein:
Amine oxidase [flavin-containing] BSubstance-P receptorAmine oxidase [flavin-containing] A
Waktu Paruh1.2-2 hours
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Selenium Compounds
Target Protein:
Inosine-5'-monophosphate dehydrogenase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Selenic acid Approved DB11068
small molecule | CAS: 7783-08-6

Selenic acid is an organic compound with the chemical formula H2SeO4. It may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential trace mineral for human health.

Kategori:
Alimentary Tract and MetabolismAntioxidantsBiological Factors +10
Waktu ParuhFollowing single or…
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Selenious acid Approved DB11127
small molecule | CAS: 7783-00-8

Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissu…

Kategori:
Alimentary Tract and MetabolismBlood and Blood Forming OrgansBlood Substitutes and Perfusion Solutions +14
Waktu Paruh30 days in beagle d…
Vol. DistribusiFollowing oral inta…
Klirens-
Genetik -
Selenium Approved DB11135
small molecule | CAS: 7782-49-2

Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]

Kategori:
Alimentary Tract and MetabolismAntioxidantsBiological Factors +14
Waktu ParuhHalf life was obser…
Vol. Distribusi-
Klirens-
Genetik -
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