Digital Pharmacy - Dashboard Peneliti

S-Phosphocysteine DB03544

small molecule

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +3

Target Protein:

N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component2-iminobutanoate/2-iminopropanoate deaminase

Waktu Paruh-

Vol. Distribusi-

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Genetik -

S-propylamine-L-cysteine DB04648

small molecule

Deskripsi belum tersedia.

Target Protein:

Arginase-1

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

S-Selanyl Cysteine DB03049

small molecule

Deskripsi belum tersedia.

Kategori:

Selenium Compounds

Target Protein:

Cysteine desulfurase

Waktu Paruh-

Vol. Distribusi-

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S-sulphocysteine DB04370

small molecule | CAS: 1637-71-4

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +3

Waktu Paruh-

Vol. Distribusi-

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Genetik -

S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate DB08217

small molecule

Deskripsi belum tersedia.

Target Protein:

Eukaryotic translation initiation factor 4EPossible exported proteinCell adhesion molecule CEACAM5 +1

Waktu Paruh-

Vol. Distribusi-

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Genetik -

S-[(1-Hydroxy-2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate DB08456

small molecule

Deskripsi belum tersedia.

Target Protein:

Endolysin

Waktu Paruh-

Vol. Distribusi-

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S-[(2E)-3,7-DIMETHYLOCTA-2,6-DIENYL] TRIHYDROGENTHIODIPHOSPHATE DB04702

small molecule

Deskripsi belum tersedia.

Target Protein:

Prenyltransferase

Waktu Paruh-

Vol. Distribusi-

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S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate DB08585

small molecule

Deskripsi belum tersedia.

Target Protein:

Actinorhodin polyketide synthase acyl carrier protein

Waktu Paruh-

Vol. Distribusi-

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S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate DB08586

small molecule

Deskripsi belum tersedia.

Target Protein:

Actinorhodin polyketide synthase acyl carrier protein

Waktu Paruh-

Vol. Distribusi-

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S-[3-(3,4-DICHLOROPHENYL)-3-OXOPROPYL]-L-CYSTEINE DB07590

small molecule

Deskripsi belum tersedia.

Target Protein:

Sortase

Waktu Paruh-

Vol. Distribusi-

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S-[5-(TRIFLUOROMETHYL)-4H-1,2,4-TRIAZOL-3-YL] 5-(PHENYLETHYNYL)FURAN-2-CARBOTHIOATE DB07743

small molecule

Deskripsi belum tersedia.

Target Protein:

Replicase polyprotein 1abReplicase polyprotein 1a

Waktu Paruh-

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S-{2-[(2-chloro-4-sulfamoylphenyl)amino]-2-oxoethyl} 6-methyl-3,4-dihydroquinoline-1(2H)-carbothioate DB08494

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyprotein

Waktu Paruh-

Vol. Distribusi-

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S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine DB02689

small molecule

Deskripsi belum tersedia.

Target Protein:

Arginase-1

Waktu Paruh-

Vol. Distribusi-

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S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE DB07602

small molecule

Deskripsi belum tersedia.

Target Protein:

Epidermal growth factor receptor

Waktu Paruh-

Vol. Distribusi-

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S64315 DB17559

small molecule | CAS: 1799631-75-6

S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell leukemia 1 (Mcl-1).[A257311]

Waktu Paruh-

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S65487 DB17556

small molecule | CAS: 1644600-79-2

S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.

Waktu Paruh-

Vol. Distribusi-

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Genetik -

SAB-185 DB16491

biotech

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +7

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Sabarubicin DB12410

small molecule | CAS: 211100-13-9

Sabarubicin has been used in trials studying the treatment of Prostate Cancer, Testicular Germ Cell Tumor, and Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:

AnthracyclinesCarbohydratesGlycosides +3

Target Protein:

DNA topoisomerase 2-alphaDNA topoisomerase 2-beta

Waktu Paruh-

Vol. Distribusi-

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Sabatolimab DB16322

biotech | CAS: 2252262-24-9

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesAntineoplastic Agents +8

Waktu Paruh-

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Sabestomig DB19326

biotech | CAS: 2648346-74-9

Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).

Waktu Paruh-

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Sabirnetug DB19438

biotech | CAS: 2747959-38-0

Sabirnetug is under investigation in clinical trial NCT06335173 (A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)).

Waktu Paruh-

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Saccharide isomerate Approved DB11232

small molecule | CAS: 100843-69-4

Deskripsi belum tersedia.

Kategori:

BiopolymersCarbohydratesMacromolecular Substances +2

Waktu Paruh-

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Saccharin DB12418

small molecule | CAS: 81-07-2

Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.

Kategori:

BenzothiazolesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +9

Target Protein:

Carbonic anhydrase 1Carbonic anhydrase 9Carbonic anhydrase 12 +2

Waktu Paruh-

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Saccharomyces cerevisiae Approved DB10447

biotech | CAS: 68876-77-7

Saccharomyces cerevisiae is a fungus which can provoke allergic reactions. Saccharomyces cerevisiae is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +2

Waktu Paruh-

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Sacituzumab govitecan Approved DB12893

biotech | CAS: 1491917-83-9

Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents.[A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a re…

Kategori:

AlkaloidsAmino Acids, Peptides, and ProteinsAntibodies +20

Target Protein:

Tumor-associated calcium signal transducer 2DNA topoisomerase 1Far upstream element-binding protein 1

Waktu ParuhSacituzumab govitec…

Vol. DistribusiSacituzumab govitec…

KlirensSacituzumab govitec…

Genetik -

Sacituzumab tirumotecan DB18777

biotech | CAS: 2768350-77-0

Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.

Waktu Paruh-

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Sacrosidase Approved DB06760

biotech | CAS: 85897-35-4

Sacrosidase is a liquid enzyme preparation from S.cerevisiae used for the treatment of congenital sucrose-isomaltase deficiency (CSID). People with CSID have variable amounts of sucrose-isomaltase enzyme activity and therefore have issues metabolizing dietary…

Kategori:

Alimentary Tract and MetabolismEnzymesEnzymes and Coenzymes +3

Waktu Paruh-

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Sacubitril Approved DB09292

small molecule | CAS: 149709-62-6

Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. It was approved by the FDA after being given t…

Kategori:

Acids, AcyclicAgents causing angioedemaAmino Acids +13

Target Protein:

Neprilysin

Waktu ParuhThe half life of sa…

Vol. Distribusi103 L

Klirens-

Genetik -

Sacubitrilat DB14127

small molecule | CAS: 149709-44-4

A metabolite of LCZ696 with neprilysin inhibitory activity.

Kategori:

Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +4

Target Protein:

Neprilysin

Waktu Paruh-

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Genetik -

Safflower Approved DB10905

biotech

Safflower allergenic extract is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1

Waktu Paruh-

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Safflower oil Approved DB09446

biotech | CAS: 8001-23-8

Safflower (_Carthamus tinctorius_ L) is a herbaceous plant in the Asteraceae family. Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids, monounsaturated fatty acid (oleic acid) or essential n-6 polyunsatura…

Kategori:

Biological ProductsComplex MixturesDiet, Food, and Nutrition +10

Waktu ParuhNo pharmacokinetic …

Vol. DistribusiNo pharmacokinetic …

KlirensNo pharmacokinetic …

Genetik -

Safinamide Approved DB06654

small molecule | CAS: 133865-89-1

Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.

Kategori:

Agents that produce hypertensionAgents that reduce seizure thresholdAmines +27

Target Protein:

Amine oxidase [flavin-containing] B

Waktu Paruh22 h

Vol. Distribusi1.8 litres/kg

Klirenstotal oral clearanc…

Genetik -

Safingol DB11924

small molecule | CAS: 15639-50-6

Safingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:

AlcoholsAminesAmino Alcohols +3

Waktu Paruh-

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Safrazine DB09253

small molecule | CAS: 33419-68-0

Safrazine is a member of the hydrazine family with non-selective and irreversible inhibitor effects against monoamine oxidases. In 1960, it was used as an antidepressant but it is now discontinued.

Kategori:

Agents that produce hypertensionAgents that reduce seizure thresholdAntidepressive Agents +4

Waktu Paruh-

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Safusidenib DB18745

small molecule | CAS: 1898206-17-1

Deskripsi belum tersedia.

Waktu Paruh-

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Genetik -

Sage Approved DB10982

biotech

Sage allergenic extract is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1

Waktu Paruh-

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Sage oil DB11199

biotech | CAS: 8022-56-8

Sage oil is extracted from sage or *Salvia officinalis*, the herb commonly used for culinary purposes. *Salvia officinalis* is a common sage and a member of the genus *Salvia*, that includes aromatic and perennial plants with flowers. Essential oil has been t…

Kategori:

Agents that reduce seizure thresholdNon-Standardized Food Allergenic ExtractNon-Standardized Plant Allergenic Extract

Waktu Paruh-

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Sagopilone DB12391

small molecule | CAS: 305841-29-6

Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to comb…

Kategori:

Anti-Bacterial AgentsAntineoplastic AgentsCytochrome P-450 CYP3A Inhibitors +8

Waktu Paruh-

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Sakuranetin DB08517

small molecule | CAS: 2957-21-3

Deskripsi belum tersedia.

Kategori:

BenzopyransBiological FactorsChromones +3

Target Protein:

Adenosine receptor A2bAdenosine receptor A1Adenosine receptor A3 +1

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Salcaprozic acid DB18517

small molecule | CAS: 183990-46-7

Deskripsi belum tersedia.

Waktu Paruh-

Vol. Distribusi-

Klirens-

Genetik -

Salicin DB19357

small molecule | CAS: 138-52-3

Deskripsi belum tersedia.

Kategori:

AlcoholsAnalgesicsAnalgesics, Non-Narcotic +11

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Salicylamide Approved DB08797

small molecule | CAS: 65-45-2

Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with bo…

Kategori:

Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +16

Waktu Paruh-

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Salicylamide O-acetic acid DB16000

small molecule | CAS: 25395-22-6

Deskripsi belum tersedia.

Kategori:

Amides

Waktu Paruh-

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Salicylanilide Approved DB19376

small molecule | CAS: 87-17-2

Deskripsi belum tersedia.

Kategori:

AmidesAminesAnilides +2

Waktu Paruh-

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Salicylhydroxamic Acid DB03819

small molecule | CAS: 89-73-6

Deskripsi belum tersedia.

Kategori:

AmidesAnti-Infective AgentsAntifungal Agents +3

Target Protein:

Dihydroorotate dehydrogenase (quinone), mitochondrial

Waktu Paruh-

Vol. Distribusi-

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Genetik -

Salicylic acid Approved DB00936

small molecule | CAS: 69-72-7

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.

Kategori:

Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +35

Target Protein:

Carbonic anhydrase 6Carbonic anhydrase 12Carbonic anhydrase 2 +5

Waktu Paruh-

Vol. DistribusiThe volume of distr…

Klirens-

Genetik -

Salinomycin DB11544

small molecule | CAS: 53003-10-4

Deskripsi belum tersedia.

Kategori:

Anti-Bacterial AgentsAnti-Infective AgentsAntiparasitic Agents +8

Waktu Paruh-

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Salirasib DB12681

small molecule | CAS: 162520-00-5

Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.

Kategori:

Acids, CarbocyclicAlcoholsAntineoplastic Agents +11

Target Protein:

Serine/threonine-protein kinase mTORGTPase NRas

Waktu Paruh-

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Salix alba bark Approved DB14274

biotech

Salix alba bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:

Herbs and Natural Products

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Salix alba bark volatile oil DB14354

biotech

Salix alba bark volatile oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-

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