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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Hasil Pencarian (17430)

Halaman 292 / 349
RU85493 DB01908
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RU90395 DB02432
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rubella virus vaccine Approved DB10317
biotech

Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, …

Kategori:
Actively Acquired ImmunityAntiinfectives for Systemic UseLive Attenuated Rubella Virus Vaccine +5
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Rubidium Approved DB11346
small molecule | CAS: 7440-17-7

Deskripsi belum tersedia.

Kategori:
ElementsMetalsMetals, Alkali +1
Waktu Paruh-
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Genetik -
Rubidium Rb-82 Approved DB09479
small molecule

Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial p…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu Paruh1.27 minutes
Vol. Distribusi-
Klirens-
Genetik -
Rubitecan DB06159
small molecule | CAS: 91421-42-0

Deskripsi belum tersedia.

Kategori:
AlkaloidsAntineoplastic AgentsEnzyme Inhibitors +2
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ruboxistaurin DB11829
small molecule | CAS: 169939-94-0

Ruboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus.

Kategori:
Acids, AcyclicDicarboxylic AcidsEnzyme Inhibitors +4
Target Protein:
Peptide deformylase, mitochondrialProtein kinase C beta type
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rucaparib Approved DB12332
small molecule | CAS: 283173-50-2

Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair.[A18745] Rucaparib is proposed to work in several PARP-dependent and PARP-independent mechanisms of action; however…

Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Inhibitors +47
Target Protein:
Poly [ADP-ribose] polymerase 1Poly [ADP-ribose] polymerase 2Protein mono-ADP-ribosyltransferase PARP3
Waktu ParuhThe mean (coefficie…
Vol. DistribusiThe mean (coefficie…
KlirensThe mean (coefficie…
Genetik -
Rufinamide Approved DB06201
small molecule | CAS: 106308-44-5

Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.

Kategori:
AnticonvulsantsCarboxamide DerivativesCardiovascular Agents +14
Target Protein:
Sodium channel protein type 9 subunit alphaMetabotropic glutamate receptor 5
Waktu ParuhElimination half-li…
Vol. DistribusiRufinamide was even…
Klirens-
Genetik -
Rufloxacin DB13772
small molecule | CAS: 101363-10-4

Rufloxacin is a quinolone antibiotic. [A31894]

Kategori:
4-QuinolonesAnti-Bacterial AgentsAntibacterials for Systemic Use +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rugonersen DB18662
biotech | CAS: 2591587-57-2

Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of Angelman Syndrome.

Waktu Paruh-
Vol. Distribusi-
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Rulonilimab DB18922
biotech | CAS: 2417124-95-7

Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma).

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Rumex acetosella pollen Approved DB10359
biotech

Rumex acetosella pollen is the pollen of the Rumex acetosella plant. Rumex acetosella pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
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Rumex acetosella whole Approved DB14166
biotech

Rumex acetosella whole allergenic extract is used in allergenic testing.

Kategori:
Non-Standardized Food Allergenic Extract
Waktu Paruh-
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Rumex altissimus pollen Approved DB10901
biotech

Rumex altissimus pollen is the pollen of the Rumex altissimus plant. Rumex altissimus pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Rumex crispus pollen Approved DB10360
biotech

Rumex crispus pollen is the pollen of the Rumex crispus plant. Rumex crispus pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rumex crispus top Approved DB14167
biotech

Rumex crispus top allergenic extract is used in allergenic testing.

Kategori:
Non-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Rumex crispus whole Approved DB14267
biotech

Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
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Rumex obtusifolius pollen Approved DB10900
biotech

Rumex obtusifolius pollen is the pollen of the Rumex obtusifolius plant. Rumex obtusifolius pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Rumex salicifolius var. mexicanus pollen is the pollen of the Rumex salicifolius var. mexicanus plant. Rumex salicifolius var. mexicanus pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Runcaciguat DB16700
small molecule | CAS: 1402936-61-1

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesCycloparaffins
Target Protein:
Guanylate cyclase soluble subunit alpha-1Guanylate cyclase soluble subunit beta-1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Rupatadine Approved DB11614
small molecule | CAS: 158876-82-5

Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tr…

Kategori:
Antihistamines for Systemic UseBenzocycloheptenesCytochrome P-450 CYP2C19 Substrates +13
Target Protein:
Platelet-activating factor receptorHistamine H1 receptor
Waktu ParuhThe half life of el…
Vol. DistribusiThe apparent volume…
KlirensSystemic clearance …
Genetik -
Rupintrivir DB05102
small molecule | CAS: 223537-30-2

Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV) infections. Rupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells. It is designed to combat colds caused b…

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Branched-Chain +8
Target Protein:
Genome polyproteinGenome polyprotein
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Ruplizumab DB06475
biotech | CAS: 220651-94-5

Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +4
Target Protein:
CD40 ligand
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Rurioctocog alfa pegol Approved DB16007
biotech | CAS: 1417412-83-9

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated r…

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +9
Target Protein:
von Willebrand factorCoagulation factor VIII
Waktu ParuhFollowing intraveno…
Vol. DistribusiFollowing intraveno…
KlirensFollowing intraveno…
Genetik -
RUS 3108 DB05911
small molecule

RUS 3108 is being developed for the treatment of atherosclerosis, the major cause of cardiovascular disorders such as heart attacks and stroke by Dr. Reddy’s Laboratories. The drug’s Phase I clinical trials have been initiated in Europe to assess safety of …

Waktu Paruh-
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Genetik -
biotech | CAS: 875455-82-6

Chrysalin has been used in trials studying the treatment of Radius Fracture.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +11
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Ruscogenin DB15830
small molecule | CAS: 472-11-7

Deskripsi belum tersedia.

Kategori:
CholestanesFused-Ring CompoundsSapogenins +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rusfertide DB17724
biotech | CAS: 1628323-80-7

Rusfertide is a hepcidin mimetic currently being developed by Protagonist Therapeutics for the treatment of polycythemia vera and beta-thalassemia.

Waktu Paruh-
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Rutin Approved DB01698
small molecule | CAS: 153-18-4

A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.

Kategori:
BenzopyransCapillary Stabilizing AgentsChromones +12
Target Protein:
Aldo-keto reductase family 1 member C3Carbonyl reductase [NADPH] 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RUTI® Vaccine DB15853
biotech

The RUTI® Vaccine contains fragmented, purified and liposomed heat-inactivated Mycobacterium tuberculosis bacilli. The vaccine has demonstrated a reasonable safety profile and potent stimulation of the immune response against tuberculosis. Much like the BCG v…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ruxolitinib Approved DB08877
small molecule | CAS: 941678-49-5

Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved in cytokine signalling and hematopoiesis.[A745…

Kategori:
Agents for Dermatitis, Excluding CorticosteroidsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +18
Target Protein:
Urokinase plasminogen activator surface receptorTyrosine-protein kinase JAK2Tyrosine-protein kinase JAK1 +2
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe mean volume of …
KlirensRuxolitinib clearan…
Genetik -
Ruzasvir DB11713
small molecule | CAS: 1613081-64-3

Ruzasvir has been used in trials studying the treatment of Hepatitis C, Hepatitis C, Chronic, and Hepatitis C Infection.

Kategori:
Anti-Infective AgentsAntiviral AgentsHeterocyclic Compounds, Fused-Ring +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ruzinurad DB19209
small molecule | CAS: 1638327-48-6

Ruzinurad is under investigation in clinical trial NCT04956432 (A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout).

Kategori:
CycloparaffinsHeterocyclic Compounds, Fused-Ring
Target Protein:
Solute carrier family 22 member 12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RVT-3101 DB18718
biotech

RVT-3101 is a fully human monoclonal antibody targeting vascular endothelial growth inhibitor, also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15. It is being investigated for ulcerative colitis.

Target Protein:
Tumor necrosis factor ligand superfamily member 15
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RWJ-51084 DB03251
small molecule

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +4
Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RWJ-56423 DB02812
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RWJ-800088 DB18693
biotech | CAS: 257287-15-3

RWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous TPO.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsPeptides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rye Approved DB10564
biotech

Rye allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 40281-79-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase, inducibleNitric oxide synthase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Thymidylate synthaseDelta-aminolevulinic acid dehydratase3',5'-cyclic-AMP phosphodiesterase 4B +15
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
ThermonucleaseListeriolysin regulatory protein
Waktu Paruh-
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Genetik -
small molecule | CAS: 26289-39-4

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsHaptensOligopeptides +1
Target Protein:
Glutathione S-transferase Mu 1Glutathione S-transferase Mu 2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Enoyl-[acyl-carrier-protein] reductase [NADH]
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glycylpeptide N-tetradecanoyltransferase 2
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Acyl carrier protein
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Acyl carrier protein
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

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Menampilkan 14551–14600 dari 17430
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