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16004

Total database: 17430
Struktur (SMILES)
12010 (75.0%)
Target
9041 (56.5%)
Genomik
112 (0.7%)
Referensi
16004 (100.0%)

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Hasil Pencarian (16004)

Halaman 292 / 321
Terodiline DB13725
small molecule | CAS: 15793-40-5

Deskripsi belum tersedia.

Kategori:
Agents causing hyperkalemiaAlkanesAmines +20
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Teropavimab DB18916
biotech | CAS: 2417213-72-8

Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Terpin hydrate Approved DB13163
small molecule | CAS: 2451-01-6

Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting with acute or chronic bronchitis, and related pulmonary conditions. It is derived from sources such as turpentine, oregano, thyme and eucalyptus. It was…

Kategori:
AlcoholsCyclohexane MonoterpenesCyclohexanes +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Terpinen-4-ol DB12816
small molecule | CAS: 562-74-3

Terpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).

Kategori:
Cytochrome P-450 CYP2A6 SubstratesCytochrome P-450 Substrates
Target Protein:
AcetylcholinesteraseApoptosis regulator Bcl-2E3 ubiquitin-protein ligase XIAP +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Terpineol DB15956
small molecule | CAS: 8000-41-7

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 8007-35-0

Deskripsi belum tersedia.

Kategori:
Perfume
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
TERT-572 DB17286
biotech | CAS: 255706-49-1

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsCarrier ProteinsDNA Nucleotidyltransferases +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
tert-butanol DB03900
small molecule | CAS: 75-65-0

Deskripsi belum tersedia.

Kategori:
AlcoholsButanolsFatty Alcohols +1
Target Protein:
Calmodulin-2Calmodulin-1Calmodulin-3 +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin K
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
HTH-type transcriptional regulator EthR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Collagenase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Queuine tRNA-ribosyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Methionine aminopeptidase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin K
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tertatolol DB13775
small molecule | CAS: 83688-84-0

Tertatolol is a beta blocker.

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-Antagonists +13
Target Protein:
5-hydroxytryptamine receptor 1A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tertomotide DB12747
biotech | CAS: 915019-08-8

Tertomotide is under investigation in clinical trial NCT01223209 (A Study, Combination, Immunologic Study of LTX-315 as adjunct to tertomotide in Patients Following Curative Surgery for Carcinoma). It is a peptide vaccine that activates the immune system so t…

Target Protein:
Telomerase reverse transcriptase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tesaglitazar DB06536
small molecule | CAS: 251565-85-2

Tesaglitazar is a dual peroxisome proliferator-activated receptor alpha/gamma agonist which improves apolipoprotein levels in non-diabetic subjects with insulin resistance. Tesaglitazar is a proposed treatment for type 2 diabetes and has completed several pha…

Kategori:
Acids, CarbocyclicAlkanesAlkanesulfonic Acids +4
Target Protein:
Peroxisome proliferator-activated receptor gammaPeroxisome proliferator-activated receptor alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tesamorelin Approved DB08869
biotech | CAS: 218949-48-5

Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition…

Kategori:
Amino Acids, Peptides, and ProteinsAnterior Pituitary Lobe Hormones and AnaloguesGrowth Hormone Releasing Factor Analog +17
Target Protein:
Growth hormone-releasing hormone receptor
Waktu Paruh26 and 38 minutes i…
Vol. Distribusi9.4±3.1 L/kg in hea…
Klirens-
Genetik -
Tesetaxel DB12019
small molecule | CAS: 333754-36-2

Tesetaxel has been used in trials studying the treatment of Cancer, Melanoma, Prostate Cancer, Gastric Carcinoma, and Advanced Melanoma, among others.

Kategori:
CyclodecanesCycloparaffinsDiterpenes +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tesevatinib DB11973
small molecule | CAS: 781613-23-8

Tesevatinib has been used in trials studying the treatment of Cancer, Stomach Cancer, Brain Metastases, Esophageal Cancer, and Leptomeningeal Metastases, among others. Tesevatinib is a potent inhibitor of multiple RTKs implicated in driving tumor cell prol…

Kategori:
Antineoplastic AgentsAza CompoundsEnzyme Inhibitors +6
Target Protein:
Ephrin type-B receptor 4Pro-epidermal growth factorReceptor tyrosine-protein kinase erbB-2
Waktu Paruh50-70 hours
Vol. Distribusi-
Klirens-
Genetik -
Tesidolumab DB11926
biotech | CAS: 1531594-08-7

Tesidolumab has been used in trials studying the treatment of Geographic Atrophy, Non-infectious Panuveitis, Exudative Macular Degeneration, Non-infectious Posterior Uveitis, and Age-related Macular Degeneration, among others.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tesmilifene DB04905
small molecule | CAS: 98774-23-3

Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.

Kategori:
Antiplatelet agentsBenzene DerivativesCytochrome P-450 CYP2D6 Substrates +18
Target Protein:
ATP-dependent translocase ABCB1Histamine H1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tesnatilimab DB16377
biotech | CAS: 2242758-08-1

Tesnatilimab is under investigation in clinical trial NCT04655807 (A Study of JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tesofensine DB06156
small molecule | CAS: 195875-84-4

Deskripsi belum tersedia.

Kategori:
Biogenic Monoamines, antagonists & inhibitors
Target Protein:
Insulin receptorSodium-dependent serotonin transporterSodium-dependent noradrenaline transporter +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Testolactone Approved DB00894
small molecule | CAS: 968-93-4

An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.

Kategori:
AndrostadienesAndrostanesAndrostenes +7
Target Protein:
Aromatase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Testosterone Approved DB00624
small molecule | CAS: 58-22-0

Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and dev…

Kategori:
3-Oxoandrosten (4) DerivativesAnabolic SteroidsAndrogens +33
Target Protein:
Androgen receptorEstrogen receptorMineralocorticoid receptor
Waktu ParuhThe half life of te…
Vol. DistribusiThe volume of distr…
KlirensThe mean metabolic …
Genetik -
Testosterone cypionate Approved DB13943
small molecule | CAS: 58-20-8

Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It w…

Kategori:
Anabolic AgentsAndrogensAndrostanes +33
Target Protein:
Androgen receptorEstrogen receptorMineralocorticoid receptor
Waktu ParuhThe half-life of te…
Vol. DistribusiThe volume of distr…
KlirensTestosterone cypion…
Genetik -
small molecule | CAS: 5721-91-5

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesAndrostenols +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 18625-33-7

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesAndrostenols +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Testosterone enanthate Approved DB13944
small molecule | CAS: 315-37-7

Testosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. This slow release is achieved by the presence of the enanthate ester functional group attached to the testosterone molecule.[A31615…

Kategori:
Adrenal Cortex HormonesAndrogensAndrostanes +34
Target Protein:
Androgen receptorEstrogen receptorMineralocorticoid receptor
Waktu ParuhTestosterone enanth…
Vol. DistribusiThe volume of distr…
Klirens-
Genetik -
small molecule | CAS: 15262-86-9

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesAndrostenols +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1255-49-8

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesAndrostenols +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Testosterone propionate Approved DB01420
small molecule | CAS: 57-85-2

Testosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17? propionate ester of testosterone.[T83] Testosterone propionate was developed initially by…

Kategori:
AndrogensAndrostanesAndrostenes +17
Target Protein:
Androgen receptor
Waktu ParuhTestosterone propio…
Vol. DistribusiThe registered volu…
KlirensTestosterone propio…
Genetik -
small molecule | CAS: 521-15-3

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesAndrostenols +9
Target Protein:
Neocarzinostatin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Testosterone undecanoate Approved DB13946
small molecule | CAS: 5949-44-0

Testosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the carbon 17? position.[L35970] It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone.[A246594] Ther…

Kategori:
AndrogensAndrostanesAndrostenes +32
Target Protein:
Androgen receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThere is no informa…
KlirensWhile there is limi…
Genetik -
Tetomilast DB05298
small molecule | CAS: 145739-56-6

Tetomilast has been used in trials studying the treatment of Crohn Disease, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease.

Kategori:
Sulfur Compounds
Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4D
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 12279-90-2

Tetraarsenic tetrasulfide is under investigation in clinical trial NCT05682131 (South China Children Cancer Group - Relapsed-acute Lymphoblastic Leukemia 2022 Protocol).

Kategori:
AnionsElectrolytesHydrogen Sulfide +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tetrabenazine Approved DB04844
small molecule | CAS: 58-46-8

A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders. It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August…

Kategori:
Adrenergic AgentsCytochrome P-450 CYP2D6 SubstratesCytochrome P-450 Substrates +11
Target Protein:
Synaptic vesicular amine transporterD(2) dopamine receptor
Waktu ParuhThere is interindiv…
Vol. DistribusiSteady State, IV, i…
KlirensIV, 1.67 L/min in H…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Mitogen-activated protein kinase 8Glycogen synthase kinase-3 betaMitogen-activated protein kinase 12 +15
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 2052-49-5

Deskripsi belum tersedia.

Target Protein:
Immunoglobulin kappa constantpH-gated potassium channel KcsA
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tetracaine Approved DB09085
small molecule | CAS: 94-24-6

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

Kategori:
Acids, CarbocyclicAgents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAminobenzoates +23
Target Protein:
Ryanodine receptor 1Sodium channel protein type 10 subunit alphaRyanodine receptor 2 +1
Waktu ParuhTetracaine is hydro…
Vol. DistribusiTetracaine is rapid…
KlirensTetracaine is hydro…
Genetik -
Tetrachlorodecaoxide Approved DB05389
small molecule | CAS: 92047-76-2

WF10 is a chlorite-based, immunomodulating drug is developed by Nuvo Research Inc. Certain preclinical evidence and clinical pilot data suggest that WF10 may be effective in treating certain cancers. The Corporation believes the research to-date demonstrates …

Kategori:
AnionsCompounds used in a research, industrial, or household settingElectrolytes +7
Target Protein:
E3 ubiquitin-protein transferase MAEAScavenger receptor cysteine-rich type 1 protein M130
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tetracosactide Approved DB01284
small molecule | CAS: 16960-16-0

Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the…

Kategori:
AdrenalsAdrenocortical InsufficiencyAdrenocorticotropic Hormone +16
Target Protein:
Adrenocorticotropic hormone receptor
Waktu ParuhAbout 15 minutes fo…
Vol. Distribusi-
Klirens-
Genetik -
Tetracycline Approved DB00759
small molecule | CAS: 60-54-8

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from b…

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAnti-Bacterial Agents +32
Target Protein:
30S ribosomal protein S730S ribosomal protein S1430S ribosomal protein S3 +6
Waktu Paruh6-12 hours
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1336-20-5

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 300-52-7

Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids and varicose veins [L2031]. Sodium tetradecyl…

Kategori:
Drugs that are Mainly Renally Excreted
Target Protein:
Endothelial protein C receptor
Waktu Paruh-
Vol. DistribusiIn humans, a large …
Klirens-
Genetik -
small molecule | CAS: 2921-20-2

Deskripsi belum tersedia.

Kategori:
AnionsAntioxidantsBiological Factors +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 66-40-0

Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental age…

Kategori:
AminesCardiovascular AgentsGanglion Blockers +9
Target Protein:
Potassium voltage-gated channel subfamily KQT member 3Potassium channel subfamily T member 2Potassium channel subfamily T member 1 +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 14551–14600 dari 16004
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