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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Halaman 291 / 349
Rovaleucel DB18691
biotech

Rovaleucel is an EBV-specific autologous T-cell therapy under investigation for the treatment of EBV-positive cancers.

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biotech | CAS: 1613313-09-9

Rovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma, Other Solid Tumors, Small Cell Lung Cancer, and Medullary Thyroid Cancer, among others.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
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Rovanersen DB16982
biotech | CAS: 2072901-32-5

Deskripsi belum tersedia.

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Rovatirelin DB15338
small molecule | CAS: 204386-76-5

Rovatirelin is under investigation in clinical trial NCT01384435 (A Phase II Double Blind Comparative Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)).

Kategori:
Oxazoles
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Rovazolac DB16320
small molecule | CAS: 1454288-88-0

Rovazolac is under investigation in clinical trial NCT03175354 (A Study in Subjects With Moderate Atopic Dermatitis).

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biotech | CAS: 2163074-26-6

Deskripsi belum tersedia.

Kategori:
Adeno-associated Viral Vector Therapies
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ROX-888 DB05364
small molecule

ROX-888 is ROXRO's lead compound which is currently in Phase 3 trials for the treatment of acute pain, including post-operative pain.

Target Protein:
C-C motif chemokine 3
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Roxadustat Approved DB04847
small molecule | CAS: 808118-40-3

Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that st…

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAntianemic Preparations +10
Target Protein:
Egl nine homolog 1Prolyl hydroxylase EGLN2Prolyl hydroxylase EGLN3
Waktu ParuhThe mean effective …
Vol. DistribusiThe blood-to-plasma…
KlirensThe apparent total …
Genetik -
Roxarsone DB11458
small molecule | CAS: 121-19-7

Roxarsone is an organoarsenic molecule added to poultry feed. The addition of this compound to poultry feed improves weight gain and feed efficiency as well as prevent the growth of coccidian parasites. The drug is also approved in the United States for use i…

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiparasitic Agents +3
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small molecule | CAS: 78628-28-1

Roxatidine acetate is a specific and competitive H2 receptor antagonist. It is currently approved in South Africa under the tradename Roxit.

Kategori:
Acid ReducersAlimentary Tract and MetabolismAnti-Ulcer Agents +8
Target Protein:
Histamine H2 receptor
Waktu Paruh5-6 hours
Vol. Distribusi-
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Roxithromycin Approved DB00778
small molecule | CAS: 80214-83-1

Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to [erythromycin], [azithromycin], or [clarithromycin]. It was shown to be more effective against certain Gram-negative bacteria, particularly _Legionel…

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntibacterials for Systemic Use +19
Target Protein:
50S ribosomal protein L10ATP-dependent translocase ABCB1
Waktu Paruh12 hours
Vol. Distribusi-
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Royal jelly DB14250
biotech | CAS: 8031-67-2

Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
BeesLipids
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Rozanolixizumab Approved DB14919
biotech | CAS: 1584645-37-3

Rozanolixizumab is a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P) targeting the immunoglobulin G (IgG). Rozonolixizumab itself is an IgG4P, an inactive isotype, to reduce the likelihood of unwanted chain exchange.…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
Target Protein:
IgG receptor FcRn large subunit p51
Waktu Paruh-
Vol. DistribusiThe apparent volume…
KlirensThe apparent cleara…
Genetik -
Rozibafusp Alfa DB19233
biotech | CAS: 2143449-47-0

Rozibafusp Alfa is under investigation in clinical trial NCT04058028 (Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)).

Kategori:
Amino Acids, Peptides, and ProteinsProteinsRecombinant Proteins
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Rozrolimupab DB05209
biotech | CAS: 909402-77-3

Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and the prevention of Hemolytic…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +6
Target Protein:
Rhesus blood group D antigen
Waktu Paruh-
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RP-67580 DB16742
small molecule | CAS: 135911-02-3

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingNeurokinin-1 Receptor AntagonistsNeurotransmitter Agents
Target Protein:
Substance-P receptor
Waktu Paruh-
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Genetik -
RP-72 DB17156
biotech

Deskripsi belum tersedia.

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RP-A501 DB17647
biotech

RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is being investigated for Dan…

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RP-A601 DB18339
biotech

RP-A601 is an adeno-associated virus serotype rhesus 10 vector expressing the human galactocerebrosidase (GALC) gene

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RP-L201 DB17595
biotech

Deskripsi belum tersedia.

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RP-L301 DB17661
biotech

RP-L301 is a lentiviral vector containing the human liver and erythroid pyruvate kinase gene.

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RP01 DB05751
small molecule

RP01 is a novel anti-IgE immunotherapy for allergic individuals. It is designed to induce the immune system to produce antibodies that block Immunoglobulin E (IgE), the key mediator of an allergic response. It could offer benefit to millions of asthma and all…

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RPI-78M DB05740
small molecule

RPI-78M is being developed for the treatment of multiple sclerosis (MS). Other neurological disorders that may be served by RPI-78M include myasthenia gravis (MG), muscular dystrophy (MD) and amyotrophic lateral sclerosis (ALS).

Target Protein:
Neuronal acetylcholine receptor subunit alpha-2Neuronal acetylcholine receptor subunit beta-2Neuronal acetylcholine receptor subunit alpha-7 +3
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RPI-MN DB17957
biotech

RPI-MN is a detoxified or chemically modified alpha-cobratoxin with antiviral properties.[A260132] Being developed by Nutra Pharma under the trade name PEPTERON, it is being investigated for the treatment of neurological and immune disorders.[L47107]

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RPR128515 DB04424
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
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RPR131247 DB02744
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
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rPSGL-Ig DB06256
biotech

Recombinant P-selectin glycoprotein ligand IgG fusion protein (rPSGL-Ig) is a fusion protein of human P-selectin ligand and IgG1-Fc.

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RR001 DB17369
biotech

RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).[L44276]

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RRx-001 DB12060
small molecule | CAS: 925206-65-1

RRx-001 has been used in trials studying the treatment of Lymphomas, Brain Metastases, Cholangiocarcinoma, Colorectal Neoplasms, and Malignant Solid Tumor, among others.

Kategori:
AzetinesCarbon Radioisotopes
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RS-39604 DB17050
small molecule | CAS: 161362-65-8

RS-39604 is a selective 5-HT4 receptor antagonist.[A253112]

Kategori:
AlkanesHydrocarbons, Acyclic
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rsATP7A cDNA DB17854
biotech

Deskripsi belum tersedia.

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rsPSMA Vaccine Approved DB06361
biotech

Prostate-specific membrane antigen (PSMA) is an ?100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine based on a novel rsPS…

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RST-001 DB17843
biotech

RST-001 is a non-replicating recombinant adeno-associated virus vector containing a fragment of the gene encoding channel rhodopsin-2 protein.

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RSV-604 DB15197
small molecule | CAS: 676128-63-5

RSV-604 is under investigation in clinical trial NCT00416442 (Safety, Tolerability and Pharmacokinetic Study of Single and Multiple Intravenous Doses of RSV604 in Healthy Subjects.).

Kategori:
AmidesBenzazepinesBenzene Derivatives +1
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RTA 744 DB05920
small molecule

RTA 744 is a novel anthracycline derivative that crosses the blood-brain barrier and shows significant potential for the treatment of primary and metastatic brain cancers. Anthracyclines are one of the most broadly used and effective classes of cancer therapi…

Target Protein:
DNA topoisomerase 2-alpha
Waktu Paruh-
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RTL-1000 DB17946
biotech | CAS: 1391875-03-8

RTL-1000 is a recombinant T-Cell receptor ligand being investigated for the treatment of multiple sclerosis.

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RTP-801i DB06048
biotech

RTP-801i is an siRNA drug candidate designed to inhibit the expression of the hypoxia-inducible gene RTP801. The proposed primary indication for RTP-801i is the treatment of patients with neovascular (wet) Age-related Macular Degeneration (AMD or ARMD).

Kategori:
Antisense Elements (Genetics)Nucleic AcidsNucleic Acids, Nucleotides, and Nucleosides +3
Target Protein:
DNA damage-inducible transcript 4 protein
Waktu Paruh-
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RU78191 DB04080
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU78262 DB01947
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU78299 DB03828
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU78300 DB03306
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU78783 DB02908
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU79072 DB02762
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU79073 DB03525
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
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RU79256 DB01866
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU82197 DB03268
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU82209 DB03591
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU83876 DB02336
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
Vol. Distribusi-
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RU84687 DB01678
small molecule

RU84687 is a subnanomolar and Src SH2 selective binder.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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RU85053 DB03712
small molecule

Deskripsi belum tersedia.

Target Protein:
Proto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
Vol. Distribusi-
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Genetik -
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