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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Hasil Pencarian (17430)

Halaman 284 / 349
Reboxetine Approved DB00234
small molecule | CAS: 71620-89-8

Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra. Reboxetine has t…

Kategori:
Adrenergic AgentsAdrenergic Uptake InhibitorsAntidepressive Agents +20
Target Protein:
Sodium-dependent noradrenaline transporter
Waktu Paruh12.5 hours
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REC-994 DB15616
small molecule

REC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).

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Recanaclotide DB15417
biotech | CAS: 1667762-62-0

Recanaclotide is under investigation in clinical trial NCT01712412 (Phase 2a Study of IW-9179 to Treat Functional Dyspepsia).

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Recaticimab DB19302
biotech | CAS: 2361290-85-7

Recaticimab is under investigation in clinical trial NCT06467617 (Adebrelimab Plus Chemo and Recaticimab Perioperative Treatment for Resectable NSCLC).

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Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV-2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated to the hepatitis B surface antigen[A226593]. Virus-li…

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Recifercept DB17899
biotech | CAS: 2226238-09-9

Deskripsi belum tersedia.

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Recilisib DB18310
small molecule | CAS: 334969-03-8

Deskripsi belum tersedia.

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Recoflavone DB12058
small molecule | CAS: 203191-10-0

Recoflavone has been used in trials studying the treatment of Acute Gastritis, Dry Eye Syndrome, and Chronic Gastritis.

Kategori:
BenzopyransChromonesHeterocyclic Compounds, Fused-Ring +1
Target Protein:
Nuclear factor NF-kappa-B p105 subunitTranscription factor RelBNuclear factor NF-kappa-B p100 subunit +2
Waktu Paruh-
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biotech

Alpha 1-antitrypsin is a glycoprotein primarily produced by hepatocytes, and to a lesser extent, immune system cells. Recombinant alpha 1-antitrypsin (rAAT) is produced from yeast, which unlike commercially available forms of plasma-derived AAT, eliminates th…

Target Protein:
Alpha-1-antitrypsin
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biotech | CAS: 122320-05-2

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsEnzyme InhibitorsPeptides +4
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biotech

B38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angioten…

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Recombinant CD40-ligand is under investigation in clinical trial NCT00053391 (Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCarbohydrates +8
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biotech

Recombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral.

Kategori:
Adjuvants, ImmunologicADP Ribose TransferasesBacterial Toxins +14
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biotech

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biotech | CAS: 389069-73-2

Recombinant human kallikrein-1 is under investigation in clinical trial NCT01845064 (A Study to Evaluate the Safety and Effectiveness of DM199 in Healthy Subjects and Type 2 Diabetes Patients).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +9
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biotech

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Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.

Kategori:
Amino Acids, Peptides, and ProteinsBiopolymersCalcium-Binding Proteins +9
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biotech

Recombinant human thrombopoietin is a full-length glycosylated cytokine produced by Chinese hamster ovary cells and is used to promote the generation of megakaryocytes and platelets.[A225691, A225696] This drug is used in the treatment of thrombocytopenia.

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The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853]. In pre-clinical trial testing on mice, rabbits, and non-human primates, the candi…

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Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen] - which have been…

Kategori:
Respiratory syncytial virus (RSV) vaccinesVaccinesViral Vaccines
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Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen] - which have been…

Kategori:
Respiratory syncytial virus (RSV) vaccinesVaccinesViral Vaccines
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Recombinant super-compound interferon (rSIFN-co) is a recombinant version of interferon alpha with modified spatial configuration. This interferon has antiviral and antitumor activity.

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biotech

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Red bell pepper Approved DB10890
biotech

Red bell pepper allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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biotech

Red blood cell-encapsulated L-asparaginase is [Asparaginase Escherichia coli] encapsulated inside donor-derived red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism. It is being investigated in cancers.[L44923]

Kategori:
AmidohydrolasesAntineoplastic AgentsEnzymes +2
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Red currant Approved DB10862
biotech

Red currant allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
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Red king crab Approved DB10526
biotech

Crab allergenic extract is used in allergenic testing.

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Red pepper Approved DB14759
biotech

Red pepper allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Red snapper Approved DB10620
biotech

Red snapper allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Redaporfin DB17219
small molecule | CAS: 1224104-08-8

Deskripsi belum tersedia.

Kategori:
AmidesBiological FactorsHeterocyclic Compounds, Fused-Ring +3
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Redasemtide DB19121
biotech | CAS: 1606186-88-2

Redasemtide is under investigation in clinical trial NCT05953480 (A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke).

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Refametinib DB06309
small molecule | CAS: 923032-37-5

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +2
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Refanezumab DB14908
biotech | CAS: 1233953-61-1

Refanezumab is under investigation in clinical trial NCT00833989 (Safety Escalating Repeat IV, in Stroke Patients).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +8
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Regadenoson Approved DB06213
small molecule | CAS: 313348-27-5

Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.

Kategori:
Adenosine A receptor agonistsAdenosine A2 Receptor AgonistsCardiac Therapy +6
Target Protein:
Adenosine receptor A2a
Waktu ParuhInitial phase: 2-4 …
Vol. DistribusiCentral compartment…
KlirensAverage plasma rena…
Genetik -
Regdanvimab Approved DB16405
biotech | CAS: 2444308-95-4

Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein.[L39140] It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +11
Target Protein:
Spike glycoprotein
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe steady-state ap…
KlirensThe mean clearance …
Genetik -
Reglitazar DB04971
small molecule | CAS: 170861-63-9

Reglitazar, an isoxazolidine-3,5-dione derivative, is being developed by Pfizer for the treatment of diabetes. It is the first non-thiazolidenedione to enter clinical trials.

Target Protein:
Peroxisome proliferator-activated receptor alphaPeroxisome proliferator-activated receptor gamma
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Regorafenib Approved DB08896
small molecule | CAS: 755037-03-7

Regorafenib is an orally-administered inhibitor of multiple kinases. It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. Approved use of Reg…

Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +31
Target Protein:
Vascular endothelial growth factor receptor 1Vascular endothelial growth factor receptor 2Vascular endothelial growth factor receptor 3 +15
Waktu ParuhRegorafenib, 160 mg…
Vol. DistribusiRegorafenib undergo…
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