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16004

Total database: 17430
Struktur (SMILES)
12010 (75.0%)
Target
9041 (56.5%)
Genomik
112 (0.7%)
Referensi
16004 (100.0%)

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Hasil Pencarian (16004)

Halaman 283 / 321
biotech

Streptococcus pneumoniae type deOAc15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains de-O-acetylated saccharides of the capsular antigens of _Streptococcus pneumoniae_ serotype 15B individually conjugat…

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Streptodornase DB19273
biotech | CAS: 37340-82-2

Streptodornase is under investigation in clinical trial NCT04252963 (Clinical Trial to Assess the Efficacy and Safety of MUCOLASE Tablet(streptokinase • Streptodornase)).

Kategori:
Deoxyribonuclease I, antagonists & inhibitorsDeoxyribonucleasesEndodeoxyribonucleases +4
Waktu Paruh-
Vol. Distribusi-
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Streptokinase Approved DB00086
biotech | CAS: 9002-01-1

Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.

Kategori:
Agents causing angioedemaAmino Acids, Peptides, and ProteinsAnticoagulants +15
Target Protein:
PlasminogenProteinase-activated receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Streptolydigin DB04785
small molecule | CAS: 7229-50-7

Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsCarbohydrates +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Streptomycin Approved DB01082
small molecule | CAS: 57-92-1

Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for…

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAminoglycoside Antibacterials +16
Target Protein:
16S ribosomal RNA23S ribosomal RNA30S ribosomal protein S12 +3
Waktu ParuhStreptomycins serum…
Vol. Distribusi-
Klirens-
Genetik -
Streptozocin Approved DB00428
small molecule | CAS: 18883-66-4

An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.

Kategori:
Alkylating ActivityAlkylating DrugsAmides +18
Target Protein:
O-GlcNAcase BT_4395DNASolute carrier family 2, facilitated glucose transporter member 2 +1
Waktu Paruh5-15 minutes
Vol. Distribusi-
Klirens-
Genetik -
Strimvelis DB17594
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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STRO-001 DB17224
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Radioactive Therapeutic AgentRadiopharmaceutical Activity
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Strontium chloride Approved DB13987
small molecule | CAS: 10476-85-4

Strontium chloride (SrCl2) is a salt of strontium and chloride. SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin containing nerve endings that have become exposed by gum recession [A33167, A33168]. This…

Kategori:
Drugs that are Mainly Renally ExcretedElementsMetals +3
Waktu ParuhReadily accessible …
Vol. DistribusiThe distribution of…
KlirensDespite being the m…
Genetik -
Strontium chloride Sr-89 Approved DB09498
small molecule | CAS: 38270-90-5

Strontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. Strontium chloride is mainly used in cases of metastatic castrate-resistant prostate cancer.[A31264] Bone meta…

Kategori:
ElementsMetalsMetals, Alkaline Earth +6
Waktu ParuhStrontium chloride …
Vol. DistribusiThere have been sev…
KlirensStrontium chloride …
Genetik -
small molecule | CAS: 183133-72-4

Strontium malonate is being developed as a novel orally available pharmaceutical for the treatment and prevention of osteoporosis. It is being developed by Osteologix Inc.

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Strontium ranelate Approved DB09267
small molecule | CAS: 135459-87-9

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in wh…

Kategori:
Bone Density Conservation AgentsDrugs Affecting Bone Structure and MineralizationDrugs for Treatment of Bone Diseases +3
Waktu ParuhThe effective half-…
Vol. DistribusiStrontium has a vol…
KlirensThe plasma dclearan…
Genetik -
Strychnine DB15954
small molecule | CAS: 57-24-9

Deskripsi belum tersedia.

Kategori:
AlkaloidsCentral Nervous System AgentsCentral Nervous System Stimulants +13
Target Protein:
Glycine receptor subunit alpha-1Glycine receptor subunit alpha-2Glycine receptor subunit alpha-3 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
STX-100 DB16334
biotech | CAS: 1439902-67-6

STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).

Waktu Paruh-
Vol. Distribusi-
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STX-107 DB16943
small molecule | CAS: 935685-90-8

Deskripsi belum tersedia.

Target Protein:
Metabotropic glutamate receptor 5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Styphnolobium japonicum flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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biotech

Stypocaulon scoparium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
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Styramate DB13357
small molecule | CAS: 94-35-9

Deskripsi belum tersedia.

Kategori:
Carbamic Acid EstersCentral Nervous System DepressantsMuscle Relaxants +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
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SU-11652 DB08009
small molecule | CAS: 326914-10-7

SU-11652 is a tyrosine kinase inhibitor.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Platelet-derived growth factor receptor betaPlatelet-derived growth factor receptor alphaVascular endothelial growth factor receptor 1 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Subasumstat DB16406
small molecule | CAS: 1858276-04-6

Subasumstat is under investigation in clinical trial NCT03648372 (A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics (PK) of TAK-981 in Adult Participants With Advanced or Metastatic Solid Tumors or Relapsed/refractory Hem…

Kategori:
Experimental Unapproved Treatments for COVID-19Heterocyclic Compounds, Fused-RingSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Substance P DB19198
biotech | CAS: 33507-63-0

Substance P is under investigation in clinical trial NCT03738878 (Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1).

Kategori:
Amino Acids, Peptides, and ProteinsAutacoidsBiological Factors +11
Target Protein:
Substance-P receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succimer Approved DB00566
small molecule | CAS: 304-55-2

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.

Kategori:
Acids, AcyclicAntidotesChelating Agents +9
Target Protein:
LeadMercuryCadmium +1
Waktu Paruh48 hours
Vol. Distribusi-
Klirens-
Genetik -
Succinamide-CoA DB03905
small molecule

Deskripsi belum tersedia.

Target Protein:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinic acid Approved DB00139
small molecule | CAS: 110-15-6

A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condens…

Kategori:
Acids, AcyclicDicarboxylic AcidsDietary Supplements +3
Target Protein:
Succinate-semialdehyde dehydrogenase, mitochondrialSuccinate receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Steroid Delta-isomerase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinimide DB13376
small molecule | CAS: 123-56-8

Deskripsi belum tersedia.

Kategori:
Genito Urinary System and Sex HormonesImidesPyrrolidines +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinobucol DB05399
small molecule | CAS: 216167-82-7

AGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary artery disease.

Kategori:
Benzene DerivativesPhenols
Target Protein:
Vascular cell adhesion protein 1
Waktu Paruh-
Vol. Distribusi-
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small molecule | CAS: 604-98-8

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +7
Target Protein:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 68915-24-2

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino Acids, Peptides, and ProteinsDicarboxylic Acids +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinylcholine Approved DB00202
small molecule | CAS: 306-40-1

Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.[A19054] It has been widely used for over 50 years,[A299] most commonly in its chlori…

Kategori:
Acids, AcyclicAgents causing hyperkalemiaAmines +20
Target Protein:
Neuronal Acetylcholine (nACh) Receptor SubunitsMuscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3
Waktu ParuhThe mean half-life …
Vol. DistribusiAt intravenous dose…
KlirensThe mean _in vivo_ …
Genetik -
small molecule | CAS: 116-43-8

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAmidesAmines +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sucralfate Approved DB00364
small molecule | CAS: 54182-58-0

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to …

Kategori:
Alimentary Tract and MetabolismAluminium CompoundsAluminum Complex +14
Target Protein:
Pepsin A-5Fibroblast growth factor 2Pro-epidermal growth factor +1
Waktu ParuhThe half-life is no…
Vol. DistribusiThis drug is absorb…
KlirensSucralfate contains…
Genetik -
Sucralose DB15049
small molecule | CAS: 56038-13-2

Sucralose is an artificial sweetener used as a sugar substitute.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Sucrose Approved DB02772
small molecule | CAS: 57-50-1

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +12
Target Protein:
Beta-lactamaseTaste receptor type 1 member 2Beta-lactamase +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sucrosofate DB01901
small molecule | CAS: 57680-56-5

Deskripsi belum tersedia.

Kategori:
Anti-Ulcer AgentsCarbohydratesDisaccharides +3
Target Protein:
Fibroblast growth factor 1Fibroblast growth factor receptor 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sudapyridine DB18984
small molecule | CAS: 1859978-72-5

Sudapyridine is under investigation in clinical trial NCT05824871 (Sudapyridine (WX-081) in Rr/mdr/xdr-tuberculosis Patients).

Waktu Paruh-
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Sufentanil Approved DB00708
small molecule | CAS: 56030-54-7

Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as _Dsuvia_, the sublingual form is u…

Kategori:
Adjuvants, AnesthesiaAgents that produce hypertensionAnalgesics +25
Target Protein:
Mu-type opioid receptorDelta-type opioid receptorKappa-type opioid receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiSufentanil has a di…
KlirensThe total plasma cl…
Genetik -
Sufugolix DB06494
small molecule | CAS: 308831-61-0

Deskripsi belum tersedia.

Target Protein:
Gonadotropin-releasing hormone receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Sugammadex Approved DB06206
small molecule | CAS: 343306-71-8

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause …

Kategori:
AntidotesCarbohydratesCompounds used in a research, industrial, or household setting +6
Waktu ParuhAbout 2 hours
Vol. DistribusiAt steady state, th…
Klirens88L/min
Genetik -
Sugemalimab DB16641
biotech | CAS: 2256084-03-2

Sugemalimab is a fully human, full-length IgG4 monoclonal anti-PD-L1 antibody discovered by CStone Pharmaceuticals and being investigated against relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) in adult patients and T-cell ly…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Sulanemadlin DB17285
biotech | CAS: 1451199-98-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Sulbactam Approved DB09324
small molecule | CAS: 68373-14-8

Sulbactam is a beta (?)-lactamase inhibitor and a derivative of the basic penicillin nucleus.[L50131] When given in combination with ?-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydro…

Kategori:
AmidesAnti-Infective AgentsAntibacterials for Systemic Use +10
Target Protein:
Beta-lactamase
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe steady-state vo…
KlirensEenal clearance is …
Genetik -
small molecule | CAS: 69388-79-0

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial Agentsbeta-Lactams +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbenicillin DB13693
small molecule | CAS: 41744-40-5

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbentine DB13671
small molecule | CAS: 350-12-9

Deskripsi belum tersedia.

Kategori:
Antifungals for Dermatological UseAntifungals for Topical UseDermatologicals
Waktu Paruh-
Vol. Distribusi-
Klirens-
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Sulbutiamine DB13416
small molecule | CAS: 3286-46-2

Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other th…

Kategori:
Alimentary Tract and MetabolismPyrimidinesSulfur Compounds +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulconazole Approved DB06820
small molecule | CAS: 61318-90-9

Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +11
Target Protein:
Lanosterol 14-alpha demethylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulesomab Approved DB13976
biotech | CAS: 167747-19-5

Market product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfabenzamide Approved DB09355
small molecule | CAS: 127-71-9

Sulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.

Kategori:
AmidesSulfonesSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Menampilkan 14101–14150 dari 16004
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