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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Halaman 282 / 349
Rabeprazole Approved DB01129
small molecule | CAS: 117976-89-3

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-depend…

Kategori:
2-PyridinylmethylsulfinylbenzimidazolesAcetatesAcid Reducers +47
Target Protein:
Potassium-transporting ATPase alpha chain 1
Waktu Paruh1-2 hours (in plasm…
Vol. Distribusi-
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Rabeximod DB05772
small molecule | CAS: 872178-65-9

Rabeximod is an orally administered compound for treatment of moderate or severe active rheumatoid arthritis that is currently undergoing phase II clinical testing in eight European countries.

Kategori:
Heterocyclic Compounds, Fused-Ring
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biotech

Deskripsi belum tersedia.

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biotech

IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine. Persons previously vaccinated wit…

Kategori:
Human Rabies Immune GlobulinsSerumVaccines
Target Protein:
Rabies Virus Proteins
Waktu Paruh-
Vol. Distribusi-
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biotech

Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.

Kategori:
Actively Acquired ImmunityAntiinfectives for Systemic UseBiological Products +7
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biotech

Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.[L12795]

Kategori:
Actively Acquired ImmunityAntiinfectives for Systemic UseImmune Sera +4
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Rabusertib DB11662
small molecule | CAS: 911222-45-2

Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer.

Kategori:
AmidesAntineoplastic AgentsBenzene Derivatives +1
Target Protein:
Serine/threonine-protein kinase Chk1
Waktu Paruh-
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Raceanisodamine DB16896
small molecule | CAS: 85760-60-7

Deskripsi belum tersedia.

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Racecadotril DB11696
small molecule | CAS: 81110-73-8

Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.

Kategori:
Alimentary Tract and MetabolismAmino AcidsAmino Acids, Peptides, and Proteins +9
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Racemethionine Approved DB13972
small molecule | CAS: 59-51-8

A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +2
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Racemetyrosine DB16306
small molecule | CAS: 658-48-0

Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +3
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Racephedrine Approved DB14752
small molecule | CAS: 90-81-3

Deskripsi belum tersedia.

Kategori:
Adrenergic AgonistsAdrenergic alpha-AgonistsAdrenergic beta-Agonists +4
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Racepinephrine Approved DB11124
small molecule | CAS: 329-65-7

Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective ?- and ?-adrenergic receptor agonist. It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma includi…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-1 Receptor Agonists +30
Target Protein:
Alpha-1A adrenergic receptorAlpha-1B adrenergic receptorAlpha-2A adrenergic receptor +6
Waktu ParuhTo refer to the pha…
Vol. DistribusiTo refer to the pha…
KlirensTo refer to the pha…
Genetik -
Racivir DB12753
small molecule | CAS: 143491-54-7

Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of [emtricitabine] and its positive enantiomer. Racivir has been used in trials studying the preventio…

Kategori:
Anti-Infective AgentsAntiviral AgentsDeoxycytidine +5
Target Protein:
Reverse transcriptase/RNaseH
Waktu Paruh-
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Raclopride DB12518
small molecule | CAS: 84225-95-6

Raclopride has been used in trials studying Parkinson Disease.

Kategori:
Acids, CarbocyclicAmidesAntipsychotic Agents +13
Target Protein:
Insulin receptorD(2) dopamine receptor
Waktu Paruh-
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Racotumomab DB13045
biotech | CAS: 946832-34-4

Racotumomab has been used in trials studying the treatment of Glioma, Wilm's Tumor, Neuroblastoma, Retinoblastoma, and Ewing's Sarcoma.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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Ractopamine DB11541
small molecule

Deskripsi belum tersedia.

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-Agonists +6
Target Protein:
Estrogen receptor
Waktu Paruh-
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RAD 502 DB17328
biotech

Deskripsi belum tersedia.

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RAD-140 DB13939
small molecule | CAS: 1182367-47-0

RAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.

Kategori:
Oxazoles
Target Protein:
Androgen receptor
Waktu Paruh-
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Radafaxine DB11790
small molecule | CAS: 192374-14-4

Radafaxine has been used in trials studying the treatment of Depressive Disorder, Major.

Kategori:
KetonesPropiophenones
Target Protein:
Sodium-dependent dopamine transporterSodium-dependent noradrenaline transporter
Waktu Paruh-
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Radalbuvir DB12065
small molecule | CAS: 1314795-11-3

Radalbuvir has been used in trials studying the treatment of Chronic Hepatitis C, Chronic HCV Infection, and Chronic Hepatitis C Infection.

Kategori:
Sulfur Compounds
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Radavirsen DB15332
biotech | CAS: 1228284-45-4

Radavirsen is under investigation in clinical trial NCT01375985 (Safety Study of Single Administration Intravenous Treatment for Influenza).

Kategori:
Anti-Infective AgentsAntiviral AgentsMorpholines +5
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Rademikibart DB18995
biotech | CAS: 2648260-80-2

Rademikibart is under investigation in clinical trial NCT04773678 (Efficacy and Safety of CBP-201 in Patients With Moderate to Severe Persistent Asthma With Type 2 Inflammation).

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Radezolid DB12339
small molecule | CAS: 869884-78-6

Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsOxazoles
Target Protein:
Ribosome-binding protein 150S ribosomal protein L1
Waktu Paruh-
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Radgocitabine DB11667
small molecule | CAS: 135598-68-4

2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer.

Kategori:
ArabinonucleosidesNucleic Acids, Nucleotides, and NucleosidesNucleosides +2
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Radicicol DB03758
small molecule | CAS: 12772-57-5

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsAntifungal AgentsAntiparasitic Agents +5
Target Protein:
Heat shock protein HSP 90-alphaHeat shock protein HSP 90-betaEndoplasmin +3
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Radiprodil DB12260
small molecule | CAS: 496054-87-6

Radiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain.

Kategori:
AcetatesAcids, AcyclicAmides
Target Protein:
Glutamate receptor ionotropic, NMDA 2B
Waktu Paruh-
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Radish Approved DB10981
biotech

Radish allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Radium Ra 223 dichloride Approved DB08913
small molecule | CAS: 444811-40-9

Radium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles. As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of h…

Kategori:
Antineoplastic AgentsElementsElements, Radioactive +6
Waktu ParuhThe half-life is re…
Vol. DistribusiThe volume of distr…
KlirensThe clearance rate …
Genetik -
Radium Ra-223 DB12813
small molecule | CAS: 15623-45-7

Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC).

Kategori:
ElementsElements, RadioactiveIsotopes +4
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small molecule

Deskripsi belum tersedia.

Kategori:
alpha-Particle Emitting ActivityRadioactive alpha-Particle Emitting Therapeutic Agent
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Radotermin DB19127
biotech | CAS: 575458-75-2

Radotermin is under investigation in clinical trial NCT01182337 (A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal Rhgdf-5 for the Treatment of Early Stage Lumbar Disc Degeneration).

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Radotinib DB12323
small molecule | CAS: 926037-48-1

Radotinib is under investigation for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
Target Protein:
Tyrosine-protein kinase ABL1
Waktu Paruh-
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RAF-265 DB05984
small molecule | CAS: 927880-90-8

Deskripsi belum tersedia.

Target Protein:
Vascular endothelial growth factor receptor 2Serine/threonine-protein kinase B-raf
Waktu Paruh-
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Raffinose DB16839
small molecule | CAS: 512-69-6

Deskripsi belum tersedia.

Kategori:
CarbohydratesOligosaccharidesPolysaccharides +1
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RAG-17 DB18503
biotech

RAG-17 is a siRNA oligonucleotide designed to target and knockdown the expression of superoxide dismutase (SOD).

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Ragaglitazar DB06533
small molecule | CAS: 222834-30-2

Deskripsi belum tersedia.

Kategori:
Acids, Carbocyclic
Target Protein:
Peroxisome proliferator-activated receptor alphaPeroxisome proliferator-activated receptor gamma
Waktu Paruh-
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Ragifilimab DB18853
biotech | CAS: 2207590-51-8

Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).

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Ragweed pollen extract Approved DB05368
biotech

Ragweed pollen extract has been developed by Curalogic. The company has initiated a phase III trial with its product for oral immunotherapy of ragweed allergy. While traditional disease-modifying immunotherapeutics are administered by subcutaneous injection, …

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Rainbow trout Approved DB15540
biotech

Rainbow trout allergenic extract is used in allergenic testing.

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Ralimetinib DB11787
small molecule | CAS: 862505-00-8

Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult Glioblastoma, Fallopian Tube Cancer, and Metastatic Breast Cancer, among others.

Kategori:
Mitogen-Activated Protein Kinase 14, antagonists & inhibitors
Waktu Paruh-
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Ralinepag DB12462
small molecule | CAS: 1187856-49-0

Ralinepag has been used in trials studying the treatment of Pulmonary Arterial Hypertension.

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
Target Protein:
Prostacyclin receptor
Waktu Paruh-
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Ralmitaront DB19128
small molecule | CAS: 2133417-13-5

Ralmitaront is under investigation in clinical trial NCT04512066 (A Trial of the Efficacy and the Safety of RO6889450 (Ralmitaront) vs Placebo in Patients With an Acute Exacerbation of Schizophrenia or Schizoaffective Disorder).

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Raloxifene Approved DB00481
small molecule | CAS: 84449-90-1

Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific …

Kategori:
BCRP/ABCG2 SubstratesBenzene DerivativesBenzylidene Compounds +23
Target Protein:
Estrogen receptorEstrogen receptor betaSerpin B9 +1
Waktu ParuhThe average plasma …
Vol. DistribusiFollowing oral admi…
KlirensFollowing intraveno…
Genetik -
Raltegravir Approved DB06817
small molecule | CAS: 518048-05-0

Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive suc…

Kategori:
Agents Causing Muscle ToxicityAnti-HIV AgentsAnti-Infective Agents +13
Target Protein:
Gag-Pol polyproteinIntegrase
Waktu Paruh9 hours
Vol. DistribusiApproximately 83% b…
KlirensThe major mechanism…
Genetik -
Raltitrexed Approved DB00293
small molecule | CAS: 112887-68-0

Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.

Kategori:
AntimetabolitesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +11
Target Protein:
Thymidylate synthaseThymidylate synthaseFolylpolyglutamate synthase, mitochondrial
Waktu Paruh198 hours
Vol. Distribusi-
Klirens-
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biotech | CAS: 2610074-57-0

Raludotatug deruxtecan is under investigation in clinical trial NCT06660654 (A Study of Raludotatug Deruxtecan in Participants With Advanced/metastatic Solid Tumors (Rejoice-pantumor01)).

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Raluridine DB12894
small molecule | CAS: 119644-22-3

Raluridine has been used in trials studying the treatment of HIV Infections.

Kategori:
DeoxyribonucleosidesNucleic Acids, Nucleotides, and NucleosidesNucleosides
Target Protein:
Gag-Pol polyprotein
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Ramatercept DB15116
biotech | CAS: 1169766-01-1

Ramatercept is under investigation in clinical trial NCT00952887 (A Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ACE-031 in Healthy Postmenopausal Women).

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Ramatroban DB13036
small molecule | CAS: 116649-85-5

Ramatroban has been used in trials studying the treatment of Asthma.

Kategori:
AmidesAntiplatelet agentsHematologic Agents +5
Target Protein:
Thromboxane A2 receptorProstaglandin D2 receptor 2
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Menampilkan 14051–14100 dari 17430
Sebelumnya Halaman 282 / 349 Berikutnya