Digital Pharmacy - Dashboard Peneliti

Zorubicin DB11618

small molecule | CAS: 54083-22-6

Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.

Kategori:

AnthracyclinesAnthracyclines and Related SubstancesAntibiotics, Antineoplastic +6

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Zotarolimus DB18761

small molecule | CAS: 221877-54-9

Zotarolimus is an immunosuppressant under investigation for use in drug-eluting stents.

Kategori:

Anti-Bacterial AgentsLactonesMacrolides

Target Protein:

Serine/threonine-protein kinase mTOR

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Zotatifin DB16408

small molecule | CAS: 2098191-53-6

Zotatifin is under investigation in clinical trial NCT04092673 (Study of Eft226 in Subjects With Selected Advanced Solid Tumor Malignancies).

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Zotepine Approved DB09225

small molecule | CAS: 26615-21-4

Zotepine, with the formula (2-chloro-11-(2-dimethyl-amino-ethoxy)-dibenzo thiepin, is a neuroleptic drug. It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd.[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe…

Kategori:

Antidepressive AgentsAntipsychotic AgentsAntipsychotic Agents (Second Generation [Atypical]) +21

Target Protein:

D(1) dopamine receptorD(2) dopamine receptor5-hydroxytryptamine receptor 2A +4

Waktu ParuhThe half-life of zo…

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Zotiraciclib DB16656

small molecule | CAS: 1204918-72-8

Zotiraciclib is under investigation in clinical trial NCT02942264 (Zotiraciclib (TG02) Plus Dose-dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent…

Kategori:

Cyclin-Dependent Kinases, antagonists & inhibitorsHeterocyclic Compounds, Fused-Ring

Target Protein:

Cyclin-dependent kinase 2Cyclin-dependent kinase 9Tyrosine-protein kinase Fyn +1

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Zotizalkib DB19238

small molecule | CAS: 2648641-36-3

Deskripsi belum tersedia.

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Zoxazolamine DB19372

small molecule | CAS: 61-80-3

Deskripsi belum tersedia.

Kategori:

Antigout PreparationsAntirheumatic AgentsBenzoxazoles and derivatives +8

Target Protein:

Small conductance calcium-activated potassium channel protein 2

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ZSTK-474 DB12904

small molecule | CAS: 475110-96-4

ZSTK474 has been used in trials studying the treatment of Neoplasms.

Target Protein:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

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ZUBERITAMAB DB19443

biotech | CAS: 2251143-19-6

Zuberitamab is under investigation in clinical trial NCT06642909 (A Phase II Study of Zuberitamab Injection in Patients With Primary Membranous Nephropathy).

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Zucapsaicin Approved DB09120

small molecule | CAS: 25775-90-0

Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also known as the vanilloid o…

Kategori:

AlkaloidsAlkenesAlkynes +25

Target Protein:

Transient receptor potential cation channel subfamily V member 1

Waktu ParuhIn rats, the elimin…

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Zuclopenthixol Approved DB01624

small molecule | CAS: 53772-83-1

Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine rece…

Kategori:

Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +34

Target Protein:

D(1A) dopamine receptorD(1B) dopamine receptorD(2) dopamine receptor +4

Waktu Paruh20 hours (range 12-…

Vol. Distribusi20 L/kg.

Klirensapproximately 0.9 L…

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Zunsemetinib DB16502

small molecule | CAS: 1640282-42-3

ATI-450 was under investigation in clinical trials (NCT05279417 and NCT05216224) for treating patients with rheumatoid arthritis and hidradenitis suppurativa, respectively. Additionally, ATI-450 was studied in a terminated trial (NCT05511519) to treat patient…

Kategori:

Experimental Unapproved Treatments for COVID-19

Target Protein:

MAP kinase-activated protein kinase 2

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Zuranolone Approved DB15490

small molecule | CAS: 1632051-40-1

Zuranolone is a neuroactive steroid that acts as a positive allosteric modulator of the GABA<sub>A</sub> receptors. Unlike other more common GABA<sub>A</sub> positive allosteric modulators on the market like benzodiazepines, zuranolone can modulate both synap…

Kategori:

Antidepressive AgentsCentral Nervous System AgentsCentral Nervous System Depressants +9

Target Protein:

Gamma-aminobutyric acid receptor subunit gamma-3GABA(A) Receptor

Waktu ParuhThe terminal half-l…

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Zuretinol acetate DB12112

small molecule | CAS: 29584-22-3

Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).

Kategori:

Adjuvants, ImmunologicAlkenesAnticarcinogenic Agents +14

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ZVS101e DB18424

biotech

ZVS101e is a recombinant adeno-associated virus vector carrying human CYP4V2 gene.

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ZY19489 DB18062

small molecule | CAS: 1821293-40-6

Deskripsi belum tersedia.

Kategori:

AminesPolyamines

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ZYCOV-D DB15892

biotech

The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India[A219758]. The vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid carrying the gene of interest[L16503]. Once the plasmid D…

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ZYIL-1 DB18184

small molecule | CAS: 2455519-86-3

Deskripsi belum tersedia.

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Zytron Approved DB11768

small molecule | CAS: 299-85-4

Zytron (DMPA) is under investigation for the treatment and health services research of HIV, Lactation, Contraception, Postpartum Depression, and Immune Cells (Mucosal and Systemic). DMPA has been investigated for the prevention, treatment, and basic science o…

Kategori:

AminesOrganophosphorus CompoundsSulfur Compounds

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[(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid Ethyl Ester DB04107

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine protease 1

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[(1R)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron DB03607

small molecule

Deskripsi belum tersedia.

Target Protein:

Subtilisin Carlsberg

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[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID DB07680

small molecule

Deskripsi belum tersedia.

Target Protein:

Chymase

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[(1S)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron DB02560

small molecule

Deskripsi belum tersedia.

Target Protein:

Subtilisin Carlsberg

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[(1S)-4-[[Amino-[(2R)-2-amino-2-carboxyethyl]sulfanylmethylidene]amino]-1-carboxybutyl]azanium DB04671

small molecule

Deskripsi belum tersedia.

Target Protein:

Arginine deiminase

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[(2-AMINO-ALPHA-METHOXYIMINO-4-THIAZOLYLACETYL)AMINO]METHYLBORONIC ACID DB07599

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-lactamase TEM

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[(2-Ethoxy-1-Naphthoyl)Amino]Methylboronic Acid DB02841

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-lactamase TEMBeta-lactamase TEMBeta-lactamase

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[(2R)-1-[(2S)-2-[[(2S,3S)-1-Chloro-6-(diaminomethylideneamino)-2-hydroxyhexan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]azanium DB06841

small molecule

Deskripsi belum tersedia.

Target Protein:

Prothrombin

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[(2R,3R,4S,5S)-3,4-Dihydroxy-5-(4-oxo-4,5-dihydro-1H-pyrrolo[3,2-d]pyrimidin-7-yl)-2-pyrrolidinyl]methyl dihydrogen phosphate DB02075

small molecule

Deskripsi belum tersedia.

Target Protein:

Hypoxanthine-guanine-xanthine phosphoribosyltransferase

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[(2R,3S,4R,5R)-5-(4-acetonyl-3-carbamoyl-pyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate DB02732

small molecule

Deskripsi belum tersedia.

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[(2r,3s,4r,5r)-5-(6-Amino-9h-Purin-9-Yl)-3,4-Dihydroxytetrahydro-2-Furanyl]Methyl Sulfamate DB02916

small molecule

Deskripsi belum tersedia.

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[(2S)-4-methyl-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-yl]acetic acid DB08717

small molecule

Deskripsi belum tersedia.

Target Protein:

Carboxylesterase

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[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID DB07771

small molecule

Deskripsi belum tersedia.

Target Protein:

GTPase KRasProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit beta

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[(3R)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid DB07719

small molecule

Deskripsi belum tersedia.

Target Protein:

Tyrosine-protein phosphatase non-receptor type 1

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[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL DB07906

small molecule

Deskripsi belum tersedia.

Target Protein:

Phenylethanolamine N-methyltransferase

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[(3R,4S)-4-HYDROXY-3-METHYL-2-OXOHEXYL]PHOSPHONIC ACID DB08431

small molecule

Deskripsi belum tersedia.

Target Protein:

Type I polyketide synthase PikAIV

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[(3R,4S,5S,7R)-4,8-DIHYDROXY-3,5,7-TRIMETHYL-2-OXOOCTYL]PHOSPHONIC ACID DB08759

small molecule

Deskripsi belum tersedia.

Target Protein:

Type I polyketide synthase PikAIV

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[(3S)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid DB06887

small molecule

Deskripsi belum tersedia.

Target Protein:

Tyrosine-protein phosphatase non-receptor type 1

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[(4-{4-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Butyl}-Phenyl)-Difluoro-Methyl]-Phosphonic Acid DB04204

small molecule

Deskripsi belum tersedia.

Target Protein:

Tyrosine-protein phosphatase non-receptor type 1

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[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl hydrogen hex-5-enylphosphonate DB08475

small molecule

Deskripsi belum tersedia.

Target Protein:

Lipase EstA

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[(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE DB08198

small molecule

Deskripsi belum tersedia.

Target Protein:

Kinesin-like protein KIF11

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[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl hydrogen hex-5-enylphosphonate DB08548

small molecule

Deskripsi belum tersedia.

Target Protein:

Lipase EstA

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[(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid DB06998

small molecule

Deskripsi belum tersedia.

Target Protein:

DNA polymerase III subunit beta

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[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate DB03831

small molecule

Deskripsi belum tersedia.

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[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester DB01871

small molecule

Deskripsi belum tersedia.

Target Protein:

Cathepsin FCruzipain

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[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester DB01810

small molecule

Deskripsi belum tersedia.

Target Protein:

Cathepsin FCruzipain

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[1-(3-CHLORO-2-FORMYL-PHENYLCARBAMOYL)-2-METHYL-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER DB07956

small molecule

Deskripsi belum tersedia.

Target Protein:

Chymotrypsin-like elastase family member 1

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[1-(3-hydroxy-2-oxo-1-phenethyl-propylcarbamoyl)2-phenyl-ethyl]-carbamic acid pyridin-4-ylmethyl ester DB02128

small molecule

Deskripsi belum tersedia.

Target Protein:

Cruzipain

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[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid DB07546

small molecule

Deskripsi belum tersedia.

Target Protein:

Casein kinase II subunit alpha'

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[1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID) DB07426

small molecule

Deskripsi belum tersedia.

Target Protein:

Farnesyl pyrophosphate synthaseDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)

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[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA DB07247

small molecule

Deskripsi belum tersedia.

Target Protein:

Coagulation factor VIITissue factor

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