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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

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Hasil Pencarian (14063)

Halaman 279 / 282
Zinc carbonate DB14494
small molecule | CAS: 5263-02-5

Deskripsi belum tersedia.

Kategori:
AlkaliesAnionsCarbon Compounds, Inorganic +7
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Zinc cation DB14532
small molecule | CAS: 23713-49-7

Deskripsi belum tersedia.

Kategori:
Copper Absorption InhibitorDecreased Copper Ion AbsorptionMetal cations +3
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Zinc chloride Approved DB14533
small molecule | CAS: 7646-85-7

Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes.[L14189] Zinc chloride was granted FDA approval before 26 June 1986.[L14189]

Kategori:
AcidsAcids, NoncarboxylicAgents for Treatment of Hemorrhoids and Anal Fissures for Topical Use +20
Target Protein:
B1 bradykinin receptorMethylated-DNA--protein-cysteine methyltransferaseFructose-bisphosphate aldolase A +94
Waktu ParuhUsing a two compart…
Vol. Distribusi-
KlirensIn one study of hea…
Genetik -
Zinc citrate DB11154
small molecule | CAS: 546-46-3

Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration [A27280].

Kategori:
Metal cationsMetal divalent cationsZinc Compounds
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Zinc dibutyldithiocarbamate Approved DB14194
small molecule | CAS: 136-23-2

Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen. Sensitivity to zinc dibutyldithiocarbamate may be identified with a clinical patch test.

Kategori:
Acids, AcyclicAgents for Treatment of Hemorrhoids and Anal Fissures for Topical UseCarbamates +8
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small molecule | CAS: 15281-32-0

Deskripsi belum tersedia.

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Zinc gluconate Approved DB11248
small molecule | CAS: 4468-02-4

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081]. It is available as a trace mineral supplement and over the cou…

Kategori:
Acids, AcyclicAgents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAlimentary Tract and Metabolism +8
Waktu Paruh280 days [L2091]
Vol. DistribusiStored primarily in…
KlirensPlease refer to Dru…
Genetik -
Zinc glycinate DB14493
small molecule | CAS: 14281-83-5

Glycoprotein marker of gastrointestinal cancer.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAntigens +5
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small molecule | CAS: 14354-67-7

Deskripsi belum tersedia.

Kategori:
Biological FactorsCoordination ComplexesHeterocyclic Compounds, Fused-Ring +5
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Genetik -
small molecule | CAS: 62008-21-3

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicDermatologicalsDicarboxylic Acids
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Zinc orotate DB15720
small molecule | CAS: 60388-02-5

Deskripsi belum tersedia.

Kategori:
PyrimidinesPyrimidinones
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Zinc oxide Approved DB09321
small molecule | CAS: 1314-13-2

Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and firs…

Kategori:
Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseBasic Ointments and ProtectantsBasic Powders and Demulcents +12
Waktu ParuhIntended for local …
Vol. DistribusiIntended for local …
KlirensIntended for local …
Genetik -
Zinc phenolsulfonate Approved DB15793
small molecule | CAS: 127-82-2

Deskripsi belum tersedia.

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small molecule

Deskripsi belum tersedia.

Kategori:
Metal cationsMetal divalent cationsZinc Compounds
Target Protein:
Cytochrome c
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Zinc sulfate Approved DB09322
small molecule | CAS: 7733-02-0

Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Kategori:
Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAlimentary Tract and MetabolismAstringents +17
Waktu Paruh3 hours
Vol. DistribusiAfter absorption zi…
Klirens-
Genetik -
small molecule

Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]

Kategori:
Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseMetal cationsMetal divalent cations +2
Target Protein:
B1 bradykinin receptorMethylated-DNA--protein-cysteine methyltransferaseFructose-bisphosphate aldolase A +94
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Metal cationsMetal divalent cationsZinc Compounds
Target Protein:
Glutathione S-transferase Mu 1
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
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Zingerone DB15589
small molecule | CAS: 122-48-5

Zingerone is a pungent component of ginger.

Kategori:
Benzene DerivativesCatecholsEthers +3
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Zinlirvimab DB18867
biotech | CAS: 2417213-75-1

Zinlirvimab is under investigation in clinical trial NCT03707977 (Dual Bnab Treatment in Children).

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biotech | CAS: 1387453-03-3

Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).

Kategori:
Acute-Phase ProteinsAmino Acids, Peptides, and ProteinsAmyloid +7
Waktu Paruh-
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Zipalertinib DB18763
small molecule | CAS: 1661854-97-2

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Waktu Paruh-
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Ziprasidone Approved DB00246
small molecule | CAS: 146939-27-7

Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior.[A190525] These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the qua…

Kategori:
Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +45
Target Protein:
D(2) dopamine receptorNeuronal acetylcholine receptor subunit alpha-75-hydroxytryptamine receptor 2A +24
Waktu ParuhThe half life of zi…
Vol. DistribusiThe mean apparent v…
KlirensThe mean apparent s…
Genetik -
biotech | CAS: 2377668-38-5

Deskripsi belum tersedia.

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small molecule | CAS: 1314-23-4

Deskripsi belum tersedia.

Kategori:
Compounds used in a research, industrial, or household settingDental AlloysDental Materials +4
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Genetik -
biotech

Zirconium panitumumab Zr-89 is under investigation in clinical trial NCT05423197 (Study Evaluating Zr-panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in Head and Neck Squamous Cell Carcinoma).

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Ziresovir DB15145
small molecule | CAS: 1422500-60-4

Ziresovir is under investigation in clinical trial NCT03699202 (Anti-RSV Study in Chinese Patients (ASCENT)).

Kategori:
Anti-Infective AgentsAntiviral AgentsAzepines +3
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Ziritaxestat DB15403
small molecule | CAS: 1628260-79-6

Ziritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective and Safe GLPG1690 is for Patients With Systemic Sclerosis).

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ZK-805623 DB04432
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
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Zk-806450 DB02112
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
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ZK-93423 DB17063
small molecule | CAS: 83910-44-5

ZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor.[A253172]

Kategori:
Anti-Anxiety AgentsAnticonvulsantsCentral Nervous System Agents +7
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Gamma-aminobutyric acid receptor subunit beta-2Gamma-aminobutyric acid receptor subunit gamma-2
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ZM-39923 DB17064
small molecule | CAS: 273727-89-2

ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).[A253177]

Target Protein:
Tyrosine-protein kinase JAK1Tyrosine-protein kinase JAK3
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

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Zofenopril Approved DB13166
small molecule | CAS: 81872-10-8

Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.

Kategori:
ACE Inhibitors and DiureticsAgents Acting on the Renin-Angiotensin SystemAgents causing angioedema +10
Target Protein:
Angiotensin-converting enzyme
Waktu Paruh-
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Zofin DB16519
biotech

Zofin, previously known as Organicell Flow, is a nanoparticle-based therapeutic derived from perinatal sources which is manufactured in a way that retains the naturally occurring microRNAs without the addition of other substances[L31323].

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Zolazepam DB11555
small molecule | CAS: 31352-82-6

Zolazepam is a pyrazolodiazepinone derivative used as an anaesthetic in veterinary medicine. Zolazepam is typically used in combination with the NMDA antagonist tiletamine or the ?2 adrenoceptor agonist xylazine. It is around four times the potency of diazepa…

Kategori:
Anti-Anxiety AgentsCentral Nervous System AgentsCentral Nervous System Depressants +6
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Zolbetuximab Approved DB15118
biotech | CAS: 1496553-00-4

Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +5
Target Protein:
Claudin-18
Waktu Paruh-
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Genetik -
small molecule | CAS: 1323976-37-9

Deskripsi belum tersedia.

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Zoledronic acid Approved DB00399
small molecule | CAS: 118072-93-8

Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid].[A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hy…

Kategori:
BisphosphonatesBone Density Conservation AgentsDrugs Affecting Bone Structure and Mineralization +5
Target Protein:
Geranylgeranyl pyrophosphate synthaseHydroxylapatiteFarnesyl pyrophosphate synthase
Waktu ParuhZoledronic acid has…
Vol. Distribusi-
KlirensZoledronic acid has…
Genetik -
Zoliflodacin DB12817
small molecule | CAS: 1620458-09-4

Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.

Kategori:
Antineoplastic AgentsEnzyme InhibitorsOxazines +5
Target Protein:
DNA gyrase subunit ADNA gyrase subunit B
Waktu Paruh-
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Zolimidine DB13593
small molecule | CAS: 1222-57-7

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismDrugs for Acid Related DisordersDrugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)
Waktu Paruh-
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Zolmitriptan Approved DB00315
small molecule | CAS: 139264-17-8

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine.[A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilic…

Kategori:
Agents that produce hypertensionAminesAnalgesics +24
Target Protein:
5-hydroxytryptamine receptor 1B5-hydroxytryptamine receptor 1D5-hydroxytryptamine receptor 1F +5
Gen Terkait:
GNB3
Waktu ParuhZolmitriptan has a …
Vol. DistribusiZolmitriptan has a …
KlirensZolmitriptan has a …
Genetik 1 Varian
Zolpidem Approved DB00425
small molecule | CAS: 82626-48-0

Zolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the ti…

Kategori:
Benzodiazepine hypnotics and sedativesCentral Nervous System AgentsCentral Nervous System Depressants +21
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Gamma-aminobutyric acid receptor subunit gamma-3Gamma-aminobutyric acid receptor subunit alpha-2 +2
Waktu ParuhThe average zolpide…
Vol. Distribusi0.54 to 0.68 L/kg (…
KlirensIn a clinical trial…
Genetik -
Zomepirac DB04828
small molecule | CAS: 33369-31-2

Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +15
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2Prostaglandin D2 receptor 2
Waktu Paruh-
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Zongertinib DB18762
small molecule | CAS: 2728667-27-2

Deskripsi belum tersedia.

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Zonisamide Approved DB00909
small molecule | CAS: 68291-97-4

Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel…

Kategori:
Agents causing hyperkalemiaAmidesAnti-epileptic Agent +32
Target Protein:
Sodium channel protein type 1 subunit alphaSodium channel protein type 2 subunit alphaSodium channel protein type 3 subunit alpha +29
Waktu ParuhIn plasma, the elim…
Vol. DistribusiFollowing a 400 mg …
KlirensIn patients not tak…
Genetik -
Zopiclone Approved DB01198
small molecule | CAS: 43200-80-2

Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties.

Kategori:
Aza CompoundsBenzodiazepine hypnotics and sedativesCentral Nervous System Agents +16
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Gamma-aminobutyric acid receptor subunit alpha-2Gamma-aminobutyric acid receptor subunit alpha-3 +2
Waktu ParuhElimination half li…
Vol. Distribusi-
Klirens-
Genetik -
Zopolrestat DB08772
small molecule | CAS: 110703-94-1

Deskripsi belum tersedia.

Kategori:
Aldehyde Reductase, antagonists & inhibitorsAldose Reductase InhibitorsBlood Glucose Lowering Agents +4
Target Protein:
Aldo-keto reductase family 1 member B1Aldo-keto reductase family 1 member B10
Waktu Paruh-
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Genetik -
small molecule | CAS: 139570-93-7

Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others.

Kategori:
Amino Acids, Peptides, and ProteinsAnthracyclinesCarbohydrates +12
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu Paruh-
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Zorevunersen DB16912
biotech | CAS: 2415330-04-8

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
Menampilkan 13901–13950 dari 14063
Sebelumnya Halaman 279 / 282 Berikutnya