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ZYCOV-D DB15892

biotech

The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India[A219758]. The vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid carrying the gene of interest[L16503]. Once the plasmid D…

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ZYIL-1 DB18184

small molecule | CAS: 2455519-86-3

Deskripsi belum tersedia.

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[(1R)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron DB03607

small molecule

Deskripsi belum tersedia.

Target Protein:

Subtilisin Carlsberg

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[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID DB07680

small molecule

Deskripsi belum tersedia.

Target Protein:

Chymase

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[(1S)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron DB02560

small molecule

Deskripsi belum tersedia.

Target Protein:

Subtilisin Carlsberg

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[(1S)-4-(1-Aminobutylideneamino)-1-carboxybutyl]azanium DB03710

small molecule

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Target Protein:

Nitric oxide synthase 1

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[(2R)-1-[(2S)-2-[[(2S,3S)-1-Chloro-6-(diaminomethylideneamino)-2-hydroxyhexan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]azanium DB06841

small molecule

Deskripsi belum tersedia.

Target Protein:

Prothrombin

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[(2R,3R,4S,5S)-3,4-Dihydroxy-5-(4-oxo-4,5-dihydro-1H-pyrrolo[3,2-d]pyrimidin-7-yl)-2-pyrrolidinyl]methyl dihydrogen phosphate DB02075

small molecule

Deskripsi belum tersedia.

Target Protein:

Hypoxanthine-guanine-xanthine phosphoribosyltransferase

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[(2R,3S,4R,5R)-5-(4-acetonyl-3-carbamoyl-pyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate DB02732

small molecule

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[(2r,3s,4r,5r)-5-(6-Amino-9h-Purin-9-Yl)-3,4-Dihydroxytetrahydro-2-Furanyl]Methyl Sulfamate DB02916

small molecule

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[(2S)-4-methyl-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-yl]acetic acid DB08717

small molecule

Deskripsi belum tersedia.

Target Protein:

Carboxylesterase

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[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID DB07771

small molecule

Deskripsi belum tersedia.

Target Protein:

GTPase KRasProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit beta

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[(3R)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid DB07719

small molecule

Deskripsi belum tersedia.

Target Protein:

Tyrosine-protein phosphatase non-receptor type 1

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[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL DB07906

small molecule

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Target Protein:

Phenylethanolamine N-methyltransferase

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[(3R,4S)-4-HYDROXY-3-METHYL-2-OXOHEXYL]PHOSPHONIC ACID DB08431

small molecule

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Target Protein:

Type I polyketide synthase PikAIV

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[(3R,4S,5S,7R)-4,8-DIHYDROXY-3,5,7-TRIMETHYL-2-OXOOCTYL]PHOSPHONIC ACID DB08759

small molecule

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Target Protein:

Type I polyketide synthase PikAIV

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[(3S)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid DB06887

small molecule

Deskripsi belum tersedia.

Target Protein:

Tyrosine-protein phosphatase non-receptor type 1

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[(3S)-9-hydroxy-1-methyl-10-oxo-4,10-dihydro-3H-benzo[g]isochromen-3-yl]acetic acid DB08541

small molecule

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Target Protein:

ActII protein

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[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl hydrogen hex-5-enylphosphonate DB08475

small molecule

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Target Protein:

Lipase EstA

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[(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE DB08198

small molecule

Deskripsi belum tersedia.

Target Protein:

Kinesin-like protein KIF11

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[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl hydrogen hex-5-enylphosphonate DB08548

small molecule

Deskripsi belum tersedia.

Target Protein:

Lipase EstA

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[(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid DB06998

small molecule

Deskripsi belum tersedia.

Target Protein:

DNA polymerase III subunit beta

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[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate DB03831

small molecule

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[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester DB01871

small molecule

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Target Protein:

Cathepsin FCruzipain

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[1-(3-CHLORO-2-FORMYL-PHENYLCARBAMOYL)-2-METHYL-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER DB07956

small molecule

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Target Protein:

Chymotrypsin-like elastase family member 1

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[1-(3-hydroxy-2-oxo-1-phenethyl-propylcarbamoyl)2-phenyl-ethyl]-carbamic acid pyridin-4-ylmethyl ester DB02128

small molecule

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Target Protein:

Cruzipain

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[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid DB07546

small molecule

Deskripsi belum tersedia.

Target Protein:

Casein kinase II subunit alpha'

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[1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID) DB07426

small molecule

Deskripsi belum tersedia.

Target Protein:

Farnesyl pyrophosphate synthaseDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)

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[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA DB07247

small molecule

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Target Protein:

Coagulation factor VIITissue factor

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[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid DB03135

small molecule

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Target Protein:

Triosephosphate isomerase

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[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine DB04172

small molecule

Deskripsi belum tersedia.

Target Protein:

Urokinase-type plasminogen activator

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[2-(1-amino-2-hydroxy-propyl)-4-(1H-indol-3-ylmethylene)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetaldehyde DB03914

small molecule

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[2-(1-Amino-2-Hydroxy-Propyl)-4-(4-Fluoro-1h-Indol-3-Ylmethyl)-5-Hydroxy-Imidazol-1-Yl]-Acetic Acid DB01674

small molecule

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[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID DB07410

small molecule

Deskripsi belum tersedia.

Target Protein:

Farnesyl pyrophosphate synthaseGeranylgeranyl pyrophosphate synthaseDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)

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[2-(5-Mercapto-[1,3,4]thiadiazol-2-ylcarbamoyl)-1-phenyl-ethyl]-carbamic acid benzyl ester DB07987

small molecule

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Target Protein:

Stromelysin-1

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[2-(Methyleneamine)-4-(4-Hydroxy-Benzylidine)-5-Oxo-4,5-Dihydro-Imidazol-1-Yl]-Acetaldehyde DB03998

small molecule

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[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone DB04006

small molecule

Deskripsi belum tersedia.

Target Protein:

Cyclin-dependent kinase 2

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[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid DB02106

small molecule

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Target Protein:

Thyroid hormone receptor beta

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[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid DB02504

small molecule

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Target Protein:

Phospholipase A2, membrane associated

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[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium DB01736

small molecule

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Target Protein:

ADP/ATP translocase 1

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[4-(1,3,2-Dioxaborolan-2-Yloxy)Methyl]Benzamidine DB04109

small molecule

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Target Protein:

Trypsin-3

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[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine DB02833

small molecule

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Target Protein:

Cyclin-A2Cyclin-dependent kinase 2

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[4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE DB04764

small molecule

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Target Protein:

Tryptase beta-2

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[4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID DB07784

small molecule

Deskripsi belum tersedia.

Target Protein:

Immunoglobulin kappa constant

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[4-(4-Hydroxy-Benzyl)-2-(2-Hydroxy-1-Methyl-Ethyl)-5-Oxo-Imidazolidin-1-Yl]-Acetic Acid DB03537

small molecule

Deskripsi belum tersedia.

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[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid DB07837

small molecule

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Target Protein:

Serine/threonine-protein kinase Sgk1

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[4-(6-Chloro-Naphthalene-2-Sulfonyl)-Piperazin-1-Yl]-(3,4,5,6-Tetrahydro-2h-[1,4']Bipyridinyl-4-Yl)-Methanone DB01836

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine protease 1

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[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile DB07168

small molecule

Deskripsi belum tersedia.

Target Protein:

Calcium/calmodulin-dependent protein kinase type II subunit beta

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[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile DB07966

small molecule

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Target Protein:

Proto-oncogene tyrosine-protein kinase Src

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[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID DB08513

small molecule

Deskripsi belum tersedia.

Target Protein:

Mitogen-activated protein kinase 1Insulin receptorInsulin receptor substrate 1

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