Hasil Filter

16004

Total database: 17430
Struktur (SMILES)
12010 (75.0%)
Target
9041 (56.5%)
Genomik
112 (0.7%)
Referensi
16004 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (16004)

Halaman 271 / 321
small molecule

S-hydroxycysteine is a solid. This compound belongs to the alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. …

Target Protein:
Tyrosine-protein phosphatase non-receptor type 1M-phase inducer phosphatase 2Proto-oncogene tyrosine-protein kinase Src +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Alcohol dehydrogenase class-3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 5652-32-4

Deskripsi belum tersedia.

Target Protein:
Cysteine desulfuraseThiosulfate sulfurtransferase GlpEHydroxylamine reductase +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 2922-56-7

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsOligopeptidesPeptides
Target Protein:
Glutathione S-transferase Mu 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Chemotaxis protein CheY
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Endoglucanase G
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Casein kinase II subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1187-84-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +4
Target Protein:
Cathepsin DMethylated-DNA--protein-cysteine methyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 57564-91-7

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Asthmatic AgentsAnti-Infective Agents +19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glutathione S-transferase P
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsGlutathione Transferase, antagonists & inhibitorsOligopeptides +1
Target Protein:
Glutathione S-transferase Mu 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Aspartate 1-decarboxylaseProlyl endopeptidaseExopolyphosphatase +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lactoylglutathione lyase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 114507-35-6

Deskripsi belum tersedia.

Target Protein:
Trafficking protein particle complex subunit 6ATrafficking protein particle complex subunit 3Trafficking protein particle complex subunit 6B +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +3
Target Protein:
N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component2-iminobutanoate/2-iminopropanoate deaminase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Arginase-1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Selenium Compounds
Target Protein:
Cysteine desulfurase
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 1637-71-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Eukaryotic translation initiation factor 4EPossible exported proteinCell adhesion molecule CEACAM5 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Endolysin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Prenyltransferase
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Actinorhodin polyketide synthase acyl carrier protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Actinorhodin polyketide synthase acyl carrier protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Sortase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Replicase polyprotein 1abReplicase polyprotein 1a
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Arginase-1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Epidermal growth factor receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S64315 DB17559
small molecule | CAS: 1799631-75-6

S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell leukemia 1 (Mcl-1).[A257311]

Waktu Paruh-
Vol. Distribusi-
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Genetik -
S65487 DB17556
small molecule | CAS: 1644600-79-2

S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
SAB-185 DB16491
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sabarubicin DB12410
small molecule | CAS: 211100-13-9

Sabarubicin has been used in trials studying the treatment of Prostate Cancer, Testicular Germ Cell Tumor, and Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
AnthracyclinesCarbohydratesGlycosides +3
Target Protein:
DNA topoisomerase 2-alphaDNA topoisomerase 2-beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sabatolimab DB16322
biotech | CAS: 2252262-24-9

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntineoplastic Agents +8
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Sabestomig DB19326
biotech | CAS: 2648346-74-9

Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Sabirnetug DB19438
biotech | CAS: 2747959-38-0

Sabirnetug is under investigation in clinical trial NCT06335173 (A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)).

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Saccharide isomerate Approved DB11232
small molecule | CAS: 100843-69-4

Deskripsi belum tersedia.

Kategori:
BiopolymersCarbohydratesMacromolecular Substances +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Saccharin DB12418
small molecule | CAS: 81-07-2

Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.

Kategori:
BenzothiazolesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +9
Target Protein:
Carbonic anhydrase 1Carbonic anhydrase 9Carbonic anhydrase 12 +2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Saccharomyces cerevisiae Approved DB10447
biotech | CAS: 68876-77-7

Saccharomyces cerevisiae is a fungus which can provoke allergic reactions. Saccharomyces cerevisiae is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +2
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Genetik -
Sacituzumab govitecan Approved DB12893
biotech | CAS: 1491917-83-9

Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents.[A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a re…

Kategori:
AlkaloidsAmino Acids, Peptides, and ProteinsAntibodies +20
Target Protein:
Tumor-associated calcium signal transducer 2DNA topoisomerase 1Far upstream element-binding protein 1
Waktu ParuhSacituzumab govitec…
Vol. DistribusiSacituzumab govitec…
KlirensSacituzumab govitec…
Genetik -
biotech | CAS: 2768350-77-0

Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Sacrosidase Approved DB06760
biotech | CAS: 85897-35-4

Sacrosidase is a liquid enzyme preparation from S.cerevisiae used for the treatment of congenital sucrose-isomaltase deficiency (CSID). People with CSID have variable amounts of sucrose-isomaltase enzyme activity and therefore have issues metabolizing dietary…

Kategori:
Alimentary Tract and MetabolismEnzymesEnzymes and Coenzymes +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sacubitril Approved DB09292
small molecule | CAS: 149709-62-6

Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. It was approved by the FDA after being given t…

Kategori:
Acids, AcyclicAgents causing angioedemaAmino Acids +13
Target Protein:
Neprilysin
Waktu ParuhThe half life of sa…
Vol. Distribusi103 L
Klirens-
Genetik -
Sacubitrilat DB14127
small molecule | CAS: 149709-44-4

A metabolite of LCZ696 with neprilysin inhibitory activity.

Kategori:
Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +4
Target Protein:
Neprilysin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Safflower oil Approved DB09446
biotech | CAS: 8001-23-8

Safflower (_Carthamus tinctorius_ L) is a herbaceous plant in the Asteraceae family. Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids, monounsaturated fatty acid (oleic acid) or essential n-6 polyunsatura…

Kategori:
Biological ProductsComplex MixturesDiet, Food, and Nutrition +10
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Safinamide Approved DB06654
small molecule | CAS: 133865-89-1

Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.

Kategori:
Agents that produce hypertensionAgents that reduce seizure thresholdAmines +27
Target Protein:
Amine oxidase [flavin-containing] B
Waktu Paruh22 h
Vol. Distribusi1.8 litres/kg
Klirenstotal oral clearanc…
Genetik -
Safingol DB11924
small molecule | CAS: 15639-50-6

Safingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
AlcoholsAminesAmino Alcohols +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Safrazine DB09253
small molecule | CAS: 33419-68-0

Safrazine is a member of the hydrazine family with non-selective and irreversible inhibitor effects against monoamine oxidases. In 1960, it was used as an antidepressant but it is now discontinued.

Kategori:
Agents that produce hypertensionAgents that reduce seizure thresholdAntidepressive Agents +4
Waktu Paruh-
Vol. Distribusi-
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Safusidenib DB18745
small molecule | CAS: 1898206-17-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sage oil DB11199
biotech | CAS: 8022-56-8

Sage oil is extracted from sage or *Salvia officinalis*, the herb commonly used for culinary purposes. *Salvia officinalis* is a common sage and a member of the genus *Salvia*, that includes aromatic and perennial plants with flowers. Essential oil has been t…

Kategori:
Agents that reduce seizure thresholdNon-Standardized Food Allergenic ExtractNon-Standardized Plant Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 13501–13550 dari 16004
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