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17430

Total database: 17430
Struktur (SMILES)
12313 (70.6%)
Target
9368 (53.7%)
Genomik
112 (0.6%)
Referensi
17430 (100.0%)

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Hasil Pencarian (17430)

Halaman 271 / 1743
ABSK-012 DB18035
small molecule | CAS: 2271209-99-3

Deskripsi belum tersedia.

Waktu Paruh-
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Genetik -
ABSK-091 DB18442
small molecule | CAS: 1035270-39-3

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesAntineoplastic Agents +2
Waktu Paruh-
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Genetik -
ABT-072 DB15156
small molecule | CAS: 1132936-00-5

ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat Hepatitis C).

Kategori:
AmidesPyrimidinesPyrimidinones +2
Target Protein:
Genome polyprotein
Waktu Paruh-
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ABT-288 DB15192
small molecule | CAS: 948845-91-8

ABT-288 is under investigation in clinical trial NCT01018875 (Efficacy and Safety Study of ABT-288 in Subjects With Mild-to-Moderate Alzheimer's Disease).

Kategori:
Histamine Antagonists
Target Protein:
Histamine H3 receptor
Waktu Paruh-
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ABT-341 DB08044
small molecule | CAS: 913623-69-5

ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different). [A39406]

Kategori:
Benzene DerivativesEnzyme InhibitorsProtease Inhibitors
Target Protein:
Dipeptidyl peptidase 4
Waktu Paruh-
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ABT-384 DB12501
small molecule | CAS: 868623-40-9

ABT-384 has been used in trials studying the treatment of Alzheimer's Disease.

Kategori:
11-beta-Hydroxysteroid Dehydrogenase Type 1, antagonists & inhibitorsBridged-Ring CompoundsCycloparaffins
Waktu Paruh-
Vol. Distribusi-
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Genetik -
ABT-510 DB05434
small molecule | CAS: 251579-55-2

ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and slows tumor growth. It is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Target Protein:
Thrombospondin-1Fibroblast growth factor 2Hepatocyte growth factor +2
Waktu Paruh-
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Genetik -
ABT-560 DB06093
small molecule

ABT-560 is a neuronal nicotinic receptor (NNR) modulator, which has shown promise in preclinical models relevant for the treatment of cognitive deficits.

Waktu Paruh-
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ABT-639 DB15055
small molecule | CAS: 1235560-28-7

ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain).

Kategori:
AmidesBenzene DerivativesHeterocyclic Compounds, Fused-Ring +3
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1H
Waktu Paruh-
Vol. Distribusi-
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Genetik -
ABT-737 DB17023
small molecule | CAS: 852808-04-9

An inhibitor of members of the Bcl?2 family of apoptosis regulators.[A252977]

Kategori:
AmidesBenzene DerivativesNitro Compounds +4
Target Protein:
Apoptosis regulator Bcl-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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