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14063

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10481 (74.5%)
Target
8038 (57.2%)
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107 (0.8%)
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14063 (100.0%)

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Hasil Pencarian (14063)

Halaman 268 / 282
Typhoid Vaccine Live Approved DB11050
biotech

Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain *Salmonella typhi* Ty21a. The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by *Salm…

Kategori:
Actively Acquired ImmunityInactivated Salmonella Typhi VaccineLive Attenuated Salmonella Typhi Vaccine +2
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biotech

Typhoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older. The vaccine contains the puri…

Kategori:
Actively Acquired ImmunityAntiinfectives for Systemic UseBacterial Vaccines +3
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Tyramine DB08841
small molecule | CAS: 51-67-2

Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An important characteristic of thi…

Kategori:
Adrenergic AgentsAgents producing tachycardiaAgents that produce hypertension +9
Target Protein:
Trace amine-associated receptor 1
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small molecule | CAS: 30223-92-8

Deskripsi belum tersedia.

Kategori:
AminesBiogenic AminesBiogenic Monoamines
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Tyropanoic acid Approved DB09340
small molecule | CAS: 27293-82-9

Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones under the trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. The molecule contains three heavy iodine atoms which obstruct X-rays in the same w…

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingContrast Media +6
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Tyrosinase DB16626
biotech | CAS: 9002-10-2

Tyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839] Within mammals, …

Kategori:
Catechol OxidaseEnzymesEnzymes and Coenzymes +6
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Tyrosine Approved DB00135
small molecule | CAS: 60-18-4

Tyrosine is a non-essential amino acid. In animals it is synthesized from [phenylalanine]. It is also the precursor of [epinephrine], thyroid hormones, and melanin.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +4
Target Protein:
Tyrosine 3-monooxygenaseTyrosine--tRNA ligase, mitochondrialTyrosine--tRNA ligase, cytoplasmic +1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Tyrosine--tRNA ligase
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Tyrothricin Approved DB13503
small molecule | CAS: 1404-88-2

Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis and Bacillus aneurinolyticus [A36353]. This complex…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Bacterial AgentsAnti-Infective Agents +9
Target Protein:
Phospholipid membraneAcetylcholinesteraseBeta-galactosidase
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small molecule | CAS: 133550-34-2

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesBenzylidene CompoundsHeterocyclic Compounds, Fused-Ring +2
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Tyrphostin B44 DB16762
small molecule | CAS: 133550-32-0

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesBenzylidene CompoundsHeterocyclic Compounds, Fused-Ring +2
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Tyrphostin B56 DB16775
small molecule | CAS: 149092-35-3

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesBenzylidene CompoundsHeterocyclic Compounds, Fused-Ring +3
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Tyvelose DB04028
small molecule | CAS: 5658-12-8

Deskripsi belum tersedia.

Kategori:
CarbohydratesMonosaccharides
Target Protein:
Tail fiber protein
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TZP-102 DB16129
small molecule | CAS: 1008993-65-4

TZP-102 is under investigation in clinical trial NCT01452815 (Affects of Once-daily Oral Administration of TZP-102 on the Treatment of Symptoms Associated With Diabetic Gastroparesis).

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U-0126 DB17060
small molecule | CAS: 218601-62-8

U-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.[A253162]

Kategori:
AlkadienesAlkenesEnzyme Inhibitors +2
Target Protein:
Mitogen-activated protein kinase kinase kinase 2Mitogen-activated protein kinase kinase kinase 1
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UB-612 DB16444
biotech

The UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components[L30653]. The vaccine incorporates a strong S1-RBD component linked to …

Kategori:
Biological ProductsComplex MixturesVaccines +1
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Ubamatamab DB18875
biotech | CAS: 2305629-50-7

Ubamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers).

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Ubenimex DB03424
small molecule | CAS: 58970-76-6

Ubenimex (also known as bestatin) is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.

Kategori:
Adjuvants, ImmunologicAmino AcidsAmino Acids, Branched-Chain +9
Target Protein:
Leukotriene A-4 hydrolaseBacterial leucyl aminopeptidase
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Ubidecarenone Approved DB09270
small molecule | CAS: 303-98-0

Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail.[A7874] It is a powerful antioxidant, a lipid-soluble and es…

Kategori:
Agents Causing Muscle ToxicityBenzoquinonesCardiac Therapy +13
Target Protein:
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrialSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Waktu ParuhThe pharmacokinetic…
Vol. DistribusiUbidecarenone is di…
KlirensIn preclinical stud…
Genetik -
Ubiquinol Approved DB11340
small molecule | CAS: 992-78-9

Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in ma…

Kategori:
BenzoquinonesCoenzymesEnzymes and Coenzymes +1
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Ubiquinone Q1 DB08689
small molecule | CAS: 727-81-1

Deskripsi belum tersedia.

Kategori:
BenzoquinonesCoenzymesEnzymes and Coenzymes +1
Target Protein:
Photosynthetic reaction center cytochrome c subunitReaction center protein H chainReaction center protein L chain +10
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Ubiquinone Q2 DB08690
small molecule | CAS: 606-06-4

Deskripsi belum tersedia.

Kategori:
AntidotesBenzoquinonesCoenzymes +10
Target Protein:
Succinate dehydrogenase flavoprotein subunitSuccinate dehydrogenase iron-sulfur subunitSuccinate dehydrogenase cytochrome b556 subunit +22
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Ublituximab Approved DB11850
biotech | CAS: 1174014-05-1

CD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers and autoimmune conditions.[A244195, A244200, A244205] Monoclonal antibodies for B cell depletion rely on their binding affinity and ability to clear bo…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +11
Target Protein:
B-lymphocyte antigen CD20
Waktu ParuhThe estimated mean …
Vol. DistribusiThe estimated centr…
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Ubrogepant Approved DB15328
small molecule | CAS: 1374248-77-7

Ubrogepant is indicated for the acute treatment of migraine headaches with or without aura in adults.[L10926] It was approved by the FDA on December 23, 2019, and is the first oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for the ac…

Kategori:
AnalgesicsAntimigraine PreparationsBCRP/ABCG2 Substrates +23
Target Protein:
Calcitonin gene-related peptide type 1 receptor
Waktu ParuhUbrogepant has an e…
Vol. DistribusiThe apparent centra…
KlirensThe apparent oral c…
Genetik -
UC-781 DB05871
small molecule | CAS: 178870-32-1

UC-781 is a thiocarboxanilide non-nucleoside reverse transcriptase inhibitor (NNRTI). It is a topical microbicide targeted against the AIDS virus.

Kategori:
AmidesAnti-Infective AgentsAnti-Retroviral Agents +2
Target Protein:
Gag-Pol polyprotein
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UCART22 DB17466
biotech

UCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes.

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UCB7362 DB17096
small molecule

UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria.[A254222] Plasmepsins are aspartyl proteases produced by the malaria parasite _Plasmodium falciparum_, and PMX is considered to be essential for paras…

Target Protein:
Plasmepsin XPlasmepsin X
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Udenafil Approved DB06267
small molecule | CAS: 268203-93-6

Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. It is not yet approved for use in the U.S., E.U., or Canada.

Kategori:
AmidesBenzene DerivativesCytochrome P-450 CYP3A Substrates +14
Target Protein:
cGMP-specific 3',5'-cyclic phosphodiesterase
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Udifitimod DB19053
small molecule | CAS: 1883345-06-9

Udifitimod is under investigation in clinical trial NCT05014438 (A Study of BMS-986166 or Branebrutinib for the Treatment of Participants With Atopic Dermatitis).

Kategori:
Naphthalenes
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Udonitrectag DB18013
small molecule | CAS: 1458063-04-1

Deskripsi belum tersedia.

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small molecule

Deskripsi belum tersedia.

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small molecule | CAS: 2616-64-0

A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation o…

Kategori:
CarbohydratesGlycosidesNucleic Acids, Nucleotides, and Nucleosides +8
Target Protein:
UDP-glucose 4-epimeraseGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3UDP-glucose 6-dehydrogenase
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UK-396,082 DB12099
small molecule | CAS: 400044-47-5

UK-396,082 has been used in trials studying the basic science of Safety, Phase 1, Toleration, Multiple Dose, and Pharmacokinetic.

Kategori:
Amino Acids, Peptides, and Proteins
Target Protein:
Carboxypeptidase B2
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UK-432097 DB12691
small molecule | CAS: 380221-63-6

UK-432,097 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.

Kategori:
Adenosine A receptor agonistsAdenosine A2 Receptor AgonistsHeterocyclic Compounds, Fused-Ring +5
Target Protein:
Adenosine receptor A2a
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UK-500001 DB12837
small molecule | CAS: 582332-31-8

UK-500,001 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.

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Ukrain cation DB17150
small molecule | CAS: 732958-87-1

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicAlkaloidsAntineoplastic Agents +3
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Ulapualide A DB03021
small molecule

Deskripsi belum tersedia.

Kategori:
Ionophores
Target Protein:
Actin, alpha skeletal muscle
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Ularitide DB05034
small molecule | CAS: 118812-69-4

Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Asthmatic AgentsAutonomic Agents +10
Target Protein:
Atrial natriuretic peptide receptor 1
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Ulefnersen DB18677
biotech | CAS: 2589926-25-8

Deskripsi belum tersedia.

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Ulenistamab DB18291
biotech | CAS: 2415259-90-2

Deskripsi belum tersedia.

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Ulevostinag DB18789
small molecule | CAS: 2082743-96-0

Deskripsi belum tersedia.

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Uliledlimab DB16675
biotech | CAS: 2378407-27-1

Uliledlimab is under investigation in clinical trial NCT04322006 (A Phase I/II Study of TJ004309 for Advanced Solid Tumor).

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Ulimorelin DB12128
small molecule | CAS: 842131-33-3

Ulimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility of the GI tract is severely impaired.

Target Protein:
Growth hormone secretagogue receptor type 1
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Ulinastatin DB12038
biotech | CAS: 80449-31-6

Ulinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to Drug.

Kategori:
Amino Acids, Peptides, and ProteinsAntifibrinolytic AgentsBlood and Blood Forming Organs +9
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Ulipristal Approved DB08867
small molecule | CAS: 159811-51-5

Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist ac…

Kategori:
Adrenal Cortex HormonesContraceptive Agents, FemaleContraceptive Agents, Hormonal +16
Target Protein:
Progesterone receptorGlucocorticoid receptorAndrogen receptor
Waktu ParuhMean elimination ha…
Vol. Distribusi-
KlirensMean oral clearance…
Genetik -
Ulixacaltamide DB18788
small molecule | CAS: 1199236-64-0

Deskripsi belum tersedia.

Kategori:
Antiarrhythmic agentsCalcium Channel BlockersCalcium-Regulating Hormones and Agents +2
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1H
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Ulixertinib DB13930
small molecule | CAS: 869886-67-9

Ulixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity [A31474]. It is currently in clinical trials for the treatment of a wide range of tumors.

Kategori:
AminesPyridines
Target Protein:
Ephrin type-B receptor 2Mitogen-activated protein kinase 3Mitogen-activated protein kinase 1
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Ulmus pumila pollen Approved DB10362
biotech

Ulmus pumila pollen is the pollen of the Ulmus pumila plant. Ulmus pumila pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Ulobetasol Approved DB00596
small molecule | CAS: 98651-66-2

Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L1…

Kategori:
Adrenal Cortex HormonesAnti-Inflammatory AgentsAntipsoriatics +15
Target Protein:
Steroid hormone receptor ERR1Steroid hormone receptor ERR2Estrogen-related receptor gamma +1
Waktu Paruh_In vitro_ experime…
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Ulocuplumab DB12018
biotech | CAS: 1375830-34-4

Ulocuplumab is under investigation in Solid Tumor.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +8
Target Protein:
C-X-C chemokine receptor type 4
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Menampilkan 13351–13400 dari 14063
Sebelumnya Halaman 268 / 282 Berikutnya