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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (14063)

Halaman 249 / 282
Substance P DB19198
biotech | CAS: 33507-63-0

Substance P is under investigation in clinical trial NCT03738878 (Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1).

Kategori:
Amino Acids, Peptides, and ProteinsAutacoidsBiological Factors +11
Target Protein:
Substance-P receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succimer Approved DB00566
small molecule | CAS: 304-55-2

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.

Kategori:
Acids, AcyclicAntidotesChelating Agents +9
Target Protein:
LeadMercuryCadmium +1
Waktu Paruh48 hours
Vol. Distribusi-
Klirens-
Genetik -
Succinic acid Approved DB00139
small molecule | CAS: 110-15-6

A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condens…

Kategori:
Acids, AcyclicDicarboxylic AcidsDietary Supplements +3
Target Protein:
Succinate-semialdehyde dehydrogenase, mitochondrialSuccinate receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Steroid Delta-isomerase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinimide DB13376
small molecule | CAS: 123-56-8

Deskripsi belum tersedia.

Kategori:
Genito Urinary System and Sex HormonesImidesPyrrolidines +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinobucol DB05399
small molecule | CAS: 216167-82-7

AGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary artery disease.

Kategori:
Benzene DerivativesPhenols
Target Protein:
Vascular cell adhesion protein 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 68915-24-2

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAmino Acids, Peptides, and ProteinsDicarboxylic Acids +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Succinylcholine Approved DB00202
small molecule | CAS: 306-40-1

Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.[A19054] It has been widely used for over 50 years,[A299] most commonly in its chlori…

Kategori:
Acids, AcyclicAgents causing hyperkalemiaAmines +20
Target Protein:
Neuronal Acetylcholine (nACh) Receptor SubunitsMuscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M3
Waktu ParuhThe mean half-life …
Vol. DistribusiAt intravenous dose…
KlirensThe mean _in vivo_ …
Genetik -
Sucralfate Approved DB00364
small molecule | CAS: 54182-58-0

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to …

Kategori:
Alimentary Tract and MetabolismAluminium CompoundsAluminum Complex +14
Target Protein:
Pepsin A-5Fibroblast growth factor 2Pro-epidermal growth factor +1
Waktu ParuhThe half-life is no…
Vol. DistribusiThis drug is absorb…
KlirensSucralfate contains…
Genetik -
Sucralose DB15049
small molecule | CAS: 56038-13-2

Sucralose is an artificial sweetener used as a sugar substitute.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sucrose Approved DB02772
small molecule | CAS: 57-50-1

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +12
Target Protein:
Beta-lactamaseTaste receptor type 1 member 2Beta-lactamase +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sudapyridine DB18984
small molecule | CAS: 1859978-72-5

Sudapyridine is under investigation in clinical trial NCT05824871 (Sudapyridine (WX-081) in Rr/mdr/xdr-tuberculosis Patients).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sufentanil Approved DB00708
small molecule | CAS: 56030-54-7

Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as _Dsuvia_, the sublingual form is u…

Kategori:
Adjuvants, AnesthesiaAgents that produce hypertensionAnalgesics +25
Target Protein:
Mu-type opioid receptorDelta-type opioid receptorKappa-type opioid receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiSufentanil has a di…
KlirensThe total plasma cl…
Genetik -
Sugammadex Approved DB06206
small molecule | CAS: 343306-71-8

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause …

Kategori:
AntidotesCarbohydratesCompounds used in a research, industrial, or household setting +6
Waktu ParuhAbout 2 hours
Vol. DistribusiAt steady state, th…
Klirens88L/min
Genetik -
Sugemalimab DB16641
biotech | CAS: 2256084-03-2

Sugemalimab is a fully human, full-length IgG4 monoclonal anti-PD-L1 antibody discovered by CStone Pharmaceuticals and being investigated against relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) in adult patients and T-cell ly…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulanemadlin DB17285
biotech | CAS: 1451199-98-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbactam Approved DB09324
small molecule | CAS: 68373-14-8

Sulbactam is a beta (?)-lactamase inhibitor and a derivative of the basic penicillin nucleus.[L50131] When given in combination with ?-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydro…

Kategori:
AmidesAnti-Infective AgentsAntibacterials for Systemic Use +10
Target Protein:
Beta-lactamase
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe steady-state vo…
KlirensEenal clearance is …
Genetik -
Sulbentine DB13671
small molecule | CAS: 350-12-9

Deskripsi belum tersedia.

Kategori:
Antifungals for Dermatological UseAntifungals for Topical UseDermatologicals
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbutiamine DB13416
small molecule | CAS: 3286-46-2

Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other th…

Kategori:
Alimentary Tract and MetabolismPyrimidinesSulfur Compounds +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulconazole Approved DB06820
small molecule | CAS: 61318-90-9

Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +11
Target Protein:
Lanosterol 14-alpha demethylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfabenzamide Approved DB09355
small molecule | CAS: 127-71-9

Sulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.

Kategori:
AmidesSulfonesSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 80-32-0

A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Kategori:
AmidesAminesAniline Compounds +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfacytine Approved DB01298
small molecule | CAS: 17784-12-2

Sulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamide…

Kategori:
AmidesAminesAniline Compounds +5
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadiazine Approved DB00359
small molecule | CAS: 68-35-9

One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

Kategori:
AmidesAminesAniline Compounds +29
Target Protein:
Dihydropteroate synthetaseDihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadicramide DB13214
small molecule | CAS: 115-68-4

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsOphthalmologicalsSensory Organs +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadimethoxine Approved DB06150
small molecule | CAS: 122-11-2

Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved…

Kategori:
AmidesAminesAniline Compounds +16
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadoxine Approved DB01299
small molecule | CAS: 2447-57-6

A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.

Kategori:
AmidesAminesAniline Compounds +15
Target Protein:
Dihydropteroate synthetaseAmine oxidase [flavin-containing] BDihydropteroate synthase +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 963-14-4

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfaguanidine DB13726
small molecule | CAS: 57-67-0

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAmidesAmidines +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 515-64-0

Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has been officially approved for use anywhere [A175672].

Kategori:
AmidesAminesAniline Compounds +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamazone DB13556
small molecule | CAS: 65761-24-2

Deskripsi belum tersedia.

Kategori:
Antibacterials for Systemic UseAntiinfectives for Systemic UseLong-Acting Antibacterial Sulfonamides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamerazine Approved DB01581
small molecule | CAS: 127-79-7

A sulfanilamide that is used as an antibacterial agent.

Kategori:
AmidesAminesAniline Compounds +16
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfameter Approved DB06821
small molecule | CAS: 651-06-9

Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.

Kategori:
AmidesAminesAniline Compounds +17
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamethazine Approved DB01582
small molecule | CAS: 57-68-1

A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.

Kategori:
AmidesAminesAniline Compounds +13
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamethizole Approved DB00576
small molecule | CAS: 144-82-1

A sulfathiazole antibacterial agent.

Kategori:
AmidesAminesAniline Compounds +26
Target Protein:
Dihydropteroate synthase
Waktu Paruh3-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Sulfamethoxazole Approved DB01015
small molecule | CAS: 723-46-6

Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria.[L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis…

Kategori:
Agents causing hyperkalemiaAgents Causing Muscle ToxicityAmines +39
Target Protein:
Dihydropteroate synthase
Waktu ParuhThe average serum h…
Vol. DistribusiThe volume of distr…
KlirensThe oral and renal …
Genetik -
small molecule | CAS: 515-59-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfametomidine DB13485
small molecule | CAS: 3772-76-7

Deskripsi belum tersedia.

Kategori:
Antibacterials for Systemic UseAntiinfectives for Systemic UseLong-Acting Antibacterial Sulfonamides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfametopyrazine Approved DB00664
small molecule | CAS: 152-47-6

Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.

Kategori:
AmidesAminesAniline Compounds +17
Target Protein:
Dihydropteroate synthetaseDihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfametrole DB15975
small molecule | CAS: 32909-92-5

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Carbonic anhydrase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamoxole DB08798
small molecule | CAS: 729-99-7

Sulfamoxole is an antibacterial in the sulfonamide class.

Kategori:
AmidesAminesAniline Compounds +14
Target Protein:
Dihydropteroate synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfanilamide Approved DB00259
small molecule | CAS: 63-74-1

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.

Kategori:
AmidesAminesAniline Compounds +21
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfanitran DB11463
small molecule | CAS: 122-16-7

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfaperin DB13320
small molecule | CAS: 599-88-2

Deskripsi belum tersedia.

Kategori:
Antibacterials for Systemic UseAntiinfectives for Systemic UseLong-Acting Antibacterial Sulfonamides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfaphenazole Approved DB06729
small molecule | CAS: 526-08-9

Sulfaphenazole is a sulfonamide antibacterial.

Kategori:
AmidesAminesAniline Compounds +27
Target Protein:
Dihydropteroate synthaseCytochrome P450 2C9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfapyridine Approved DB00891
small molecule | CAS: 144-83-2

Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.

Kategori:
AmidesAminesAniline Compounds +18
Target Protein:
Dihydropteroate synthaseDihydropteroate synthase type-1
Waktu Paruh6-14 hours.
Vol. Distribusi-
Klirens-
Genetik -
Sulfasalazine Approved DB00795
small molecule | CAS: 599-79-1

Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metab…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAlimentary Tract and Metabolism +23
Target Protein:
Broad substrate specificity ATP-binding cassette transporter ABCG2Transcription factor RelBTranscription factor p65 +12
Waktu ParuhThe observed plasma…
Vol. DistribusiFollowing intraveno…
KlirensThe calculated clea…
Genetik -
Sulfate ion DB14546
small molecule | CAS: 14808-79-8

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesIncreased Large Intestinal Motility +9
Target Protein:
Carbonic anhydrase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfathiazole Approved DB06147
small molecule | CAS: 72-14-0

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those…

Kategori:
AmidesAminesAniline Compounds +16
Target Protein:
Dihydropteroate synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 12401–12450 dari 14063
Sebelumnya Halaman 249 / 282 Berikutnya