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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

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Hasil Pencarian (13591)

Halaman 241 / 272
Sulbentine DB13671
small molecule | CAS: 350-12-9

Deskripsi belum tersedia.

Kategori:
Antifungals for Dermatological UseAntifungals for Topical UseDermatologicals
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbutiamine DB13416
small molecule | CAS: 3286-46-2

Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other th…

Kategori:
Alimentary Tract and MetabolismPyrimidinesSulfur Compounds +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulconazole Approved DB06820
small molecule | CAS: 61318-90-9

Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +11
Target Protein:
Lanosterol 14-alpha demethylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulesomab Approved DB13976
biotech | CAS: 167747-19-5

Market product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfabenzamide Approved DB09355
small molecule | CAS: 127-71-9

Sulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.

Kategori:
AmidesSulfonesSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfacetamide Approved DB00634
small molecule | CAS: 144-80-9

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.

Kategori:
AmidesAminesAniline Compounds +17
Target Protein:
Dihydropteroate synthaseDihydropteroate synthase type-1Folic acid synthesis protein FOL1
Waktu Paruh7-12.8 hours
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 80-32-0

A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Kategori:
AmidesAminesAniline Compounds +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadiazine Approved DB00359
small molecule | CAS: 68-35-9

One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

Kategori:
AmidesAminesAniline Compounds +29
Target Protein:
Dihydropteroate synthetaseDihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadicramide DB13214
small molecule | CAS: 115-68-4

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsOphthalmologicalsSensory Organs +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadimethoxine Approved DB06150
small molecule | CAS: 122-11-2

Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved…

Kategori:
AmidesAminesAniline Compounds +16
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 963-14-4

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfaguanidine DB13726
small molecule | CAS: 57-67-0

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAmidesAmidines +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 515-64-0

Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has been officially approved for use anywhere [A175672].

Kategori:
AmidesAminesAniline Compounds +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamazone DB13556
small molecule | CAS: 65761-24-2

Deskripsi belum tersedia.

Kategori:
Antibacterials for Systemic UseAntiinfectives for Systemic UseLong-Acting Antibacterial Sulfonamides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamethoxazole Approved DB01015
small molecule | CAS: 723-46-6

Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria.[L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis…

Kategori:
Agents causing hyperkalemiaAgents Causing Muscle ToxicityAmines +39
Target Protein:
Dihydropteroate synthase
Waktu ParuhThe average serum h…
Vol. DistribusiThe volume of distr…
KlirensThe oral and renal …
Genetik -
small molecule | CAS: 80-35-3

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 515-59-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfametomidine DB13485
small molecule | CAS: 3772-76-7

Deskripsi belum tersedia.

Kategori:
Antibacterials for Systemic UseAntiinfectives for Systemic UseLong-Acting Antibacterial Sulfonamides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfametrole DB15975
small molecule | CAS: 32909-92-5

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Carbonic anhydrase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfanilamide Approved DB00259
small molecule | CAS: 63-74-1

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.

Kategori:
AmidesAminesAniline Compounds +21
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfanitran DB11463
small molecule | CAS: 122-16-7

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfaperin DB13320
small molecule | CAS: 599-88-2

Deskripsi belum tersedia.

Kategori:
Antibacterials for Systemic UseAntiinfectives for Systemic UseLong-Acting Antibacterial Sulfonamides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfaphenazole Approved DB06729
small molecule | CAS: 526-08-9

Sulfaphenazole is a sulfonamide antibacterial.

Kategori:
AmidesAminesAniline Compounds +27
Target Protein:
Dihydropteroate synthaseCytochrome P450 2C9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfapyridine Approved DB00891
small molecule | CAS: 144-83-2

Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.

Kategori:
AmidesAminesAniline Compounds +18
Target Protein:
Dihydropteroate synthaseDihydropteroate synthase type-1
Waktu Paruh6-14 hours.
Vol. Distribusi-
Klirens-
Genetik -
Sulfasalazine Approved DB00795
small molecule | CAS: 599-79-1

Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metab…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAlimentary Tract and Metabolism +23
Target Protein:
Broad substrate specificity ATP-binding cassette transporter ABCG2Transcription factor RelBTranscription factor p65 +12
Waktu ParuhThe observed plasma…
Vol. DistribusiFollowing intraveno…
KlirensThe calculated clea…
Genetik -
Sulfathiazole Approved DB06147
small molecule | CAS: 72-14-0

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those…

Kategori:
AmidesAminesAniline Compounds +16
Target Protein:
Dihydropteroate synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfathiourea DB13699
small molecule | CAS: 515-49-1

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfatolamide DB13547
small molecule | CAS: 1161-88-2

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfinpyrazone Approved DB01138
small molecule | CAS: 57-96-5

A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

Kategori:
Antigout PreparationsAntiplatelet agentsBSEP/ABCB11 Substrates +19
Target Protein:
Solute carrier family 22 member 12Multidrug resistance-associated protein 1ATP-binding cassette sub-family C member 2 +1
Waktu ParuhApproximately 4-6 h…
Vol. Distribusi-
Klirens-
Genetik -
Sulfisoxazole Approved DB00263
small molecule | CAS: 127-69-5

A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.

Kategori:
AmidesAminesAniline Compounds +26
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 297-83-6

Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans [A174970].

Kategori:
Benzene DerivativesColoring AgentsCompounds used in a research, industrial, or household setting +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfogaiacol DB15992
small molecule | CAS: 7134-11-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulforaphane DB12422
small molecule | CAS: 142825-10-3

Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.

Kategori:
Anticarcinogenic AgentsAntineoplastic AgentsCompounds used in a research, industrial, or household setting +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfotep DB11497
small molecule | CAS: 3689-24-5

Deskripsi belum tersedia.

Kategori:
Organophosphorus CompoundsSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfoxone Approved DB01145
small molecule | CAS: 144-76-3

Sulfoxone is a water-soluble sulfone used as an antileprosy drug. It has been used with limited success in the treatment of dermatitis herpetiformis.

Kategori:
Antiinfectives for Systemic UseAntimycobacterialsDrugs for Treatment of Lepra +2
Target Protein:
Dihydropteroate synthetase
Waktu Paruh3-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Sulfuric acid DB11309
small molecule | CAS: 7664-93-9

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicSulfur Acids +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulglicotide DB13299
small molecule | CAS: 54182-59-1

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAmino Acids, Peptides, and ProteinsAnti-Ulcer Agents +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulindac Approved DB00605
small molecule | CAS: 38194-50-2

Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a pro…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +20
Target Protein:
Prostaglandin G/H synthase 2Aldo-keto reductase family 1 member B1Prostaglandin G/H synthase 1 +4
Waktu ParuhThe mean half-life …
Vol. Distribusi-
Klirens* Renal cl=68.12 +/…
Genetik -
Sulisobenzone DB11185
small molecule | CAS: 4065-45-6

Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations [F38]. It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage [L2153]. The UV-filter s…

Kategori:
Benzene DerivativesDrugs that are Mainly Renally ExcretedKetones +1
Target Protein:
Skin epithelial cells
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Suloctidil DB13340
small molecule | CAS: 54767-75-8

Deskripsi belum tersedia.

Kategori:
AlcoholsAminesAmino Alcohols +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulopenem etzadroxil Approved DB16335
small molecule | CAS: 1000296-70-7

Sulopenem etzadroxil is a prodrug of the penem antibacterial [sulopenem]. Like other beta-lactam antibacterials, it is a time-dependent inhibitor of bacterial cell wall synthesis.[L51768] Sulopenem etzadroxil was approved by the FDA in October 2024 for the…

Kategori:
OAT3/SLC22A8 SubstratesPenem Antibacterial
Target Protein:
Penicillin-binding protein 2Penicillin-binding protein 1APenicillin-binding protein 1B +4
Waktu ParuhIn the fasted state…
Vol. DistribusiIn the fasted state…
KlirensIn the fasted state…
Genetik -
Sulpiride Approved DB00391
small molecule | CAS: 15676-16-1

Sulpiride first appeared in published literature in 1967.[A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses.[A229683…

Kategori:
Acids, CarbocyclicAmidesAntidepressive Agents +26
Target Protein:
D(2) dopamine receptorD(3) dopamine receptorCarbonic anhydrase 2 +2
Waktu ParuhReports of the half…
Vol. DistribusiThe average volume …
KlirensThe total systemic …
Genetik -
Sulprostone DB12708
small molecule | CAS: 60325-46-4

Sulprostone has been used in trials studying Abortion, Induced.

Kategori:
Abortifacient AgentsAbortifacient Agents, NonsteroidalAutacoids +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sultamicillin Approved DB12127
small molecule | CAS: 76497-13-7

Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulthiame Approved DB08329
small molecule | CAS: 61-56-3

Deskripsi belum tersedia.

Kategori:
AmidesAnticonvulsantsBenzene Derivatives +8
Target Protein:
Carbonic anhydrase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sultopride Approved DB13273
small molecule | CAS: 53583-79-2

Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics [L5626].

Kategori:
Acids, CarbocyclicAmidesAntidepressive Agents +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sumanirole DB06477
small molecule | CAS: 179386-43-7

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
D(2) dopamine receptorD(3) dopamine receptorD(4) dopamine receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sumatriptan Approved DB00669
small molecule | CAS: 103628-46-2

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines.[A179761] S…

Kategori:
Agents that produce hypertensionAmidesAmines +33
Target Protein:
5-hydroxytryptamine receptor 1A5-hydroxytryptamine receptor 1D5-hydroxytryptamine receptor 1B +1
Gen Terkait:
GNB3
Waktu ParuhSubcutaneous sumatr…
Vol. DistribusiSumatriptan has a v…
KlirensSubcutaneous sumatr…
Genetik 1 Varian
SUN-101 DB17238
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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