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S-3APG DB17419

small molecule

S-3APG (S-3-[3-amino-phthalimido]-glutarimide) is a derivative of thalidomide with dual activity against B-cell neoplasias.[A255168]

Kategori:

Acids, CarbocyclicHeterocyclic Compounds, Fused-RingIsoindoles +4

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S-4-Nitrobutyryl-CoA DB03245

small molecule

Deskripsi belum tersedia.

Target Protein:

Glutaryl-CoA dehydrogenase, mitochondrial

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S-40503 DB13938

small molecule | CAS: 404920-28-1

S-40503 is an investigational selective androgen receptor modulator (SARM) developed for the treatment of osteoporosis by the Japanese company Kaken Pharmaceuticals.

Kategori:

Heterocyclic Compounds, Fused-Ring

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S-49076 DB16821

small molecule | CAS: 1265965-22-7

Deskripsi belum tersedia.

Kategori:

Antineoplastic AgentsHeterocyclic Compounds, Fused-RingSulfur Compounds +1

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S-55746 DB18365

small molecule | CAS: 1448584-12-0

Deskripsi belum tersedia.

Kategori:

Heterocyclic Compounds, Fused-RingOxazines

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S-777469 DB16321

small molecule | CAS: 885496-53-7

S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis).

Kategori:

Pyridines

Target Protein:

Cannabinoid receptor 2

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S-8510 DB06504

small molecule

S-8510 / SB-737552 is a BZD inverse agonist investigated for the treatment of Alzheimer’s disease and mild to moderate senile dementia. It was being codeveloped by Shionogi and GlaxoSmithKline.

Kategori:

BenzazepinesHeterocyclic Compounds, Fused-Ring

Target Protein:

Translocator protein

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S-9-(2-hydroxypropyl)adenine DB03000

small molecule | CAS: 14047-27-9

Deskripsi belum tersedia.

Target Protein:

Thymidine kinase, cytosolicThymidine kinaseAdenosine deaminase

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S-Acetyl-Cysteine DB02039

small molecule

Deskripsi belum tersedia.

Target Protein:

Histone acetyltransferase KAT5Acetyl-CoA acetyltransferase3-oxoacyl-[acyl-carrier-protein] synthase 3 +1

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S-Adenosyl-1,8-Diamino-3-Thiooctane DB02844

small molecule | CAS: 76426-40-9

Deskripsi belum tersedia.

Kategori:

Heterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and NucleosidesNucleosides +3

Target Protein:

Polyamine aminopropyltransferase

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S-adenosyl-L-homocysteine DB01752

small molecule | CAS: 979-92-0

5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.

Kategori:

Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +7

Target Protein:

DNA (cytosine-5)-methyltransferase 3BHistamine N-methyltransferaseCap-specific mRNA (nucleoside-2'-O-)-methyltransferase +34

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S-Adenosyl-L-Homoselenocysteine DB03423

small molecule

Deskripsi belum tersedia.

Kategori:

Selenium Compounds

Target Protein:

tRNA (cmo5U34)-methyltransferase

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S-Apomorphine DB16927

small molecule | CAS: 39478-62-1

Deskripsi belum tersedia.

Target Protein:

D(1A) dopamine receptorD(2) dopamine receptor

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S-Arsonocysteine DB03352

small molecule

Deskripsi belum tersedia.

Target Protein:

Arsenate reductaseProtein ArsC3-mercaptopyruvate sulfurtransferase

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S-azabisabolene DB02099

small molecule

Deskripsi belum tersedia.

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S-benzylglutathione DB03602

small molecule

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsLactoylglutathione Lyase, antagonists & inhibitorsOligopeptides +1

Target Protein:

Lactoylglutathione lyaseGlutathione S-transferase A1

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S-Butyryl-Cystein DB02160

small molecule

Deskripsi belum tersedia.

Target Protein:

Acetyl-CoA acetyltransferase

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S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea DB02991

small molecule

Deskripsi belum tersedia.

Target Protein:

Nitric oxide synthase 1

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S-Ethylisothiourea DB02234

small molecule | CAS: 2986-20-1

S-Ethylisothiourea is a nitric oxide synthase inhibitor.

Kategori:

AmidesCardiovascular AgentsCentral Nervous System Agents +7

Target Protein:

Nitric oxide synthase, inducibleNitric oxide synthase 3Nitric oxide synthase oxygenase

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S-Hexylglutathione DB04132

small molecule | CAS: 24425-56-7

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsEnzyme InhibitorsLactoylglutathione Lyase, antagonists & inhibitors +2

Target Protein:

Hematopoietic prostaglandin D synthaseLactoylglutathione lyaseGlutathione S-transferase Mu 4 +4

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S-Hydroxycysteine DB01915

small molecule

S-hydroxycysteine is a solid. This compound belongs to the alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. …

Target Protein:

Tyrosine-protein phosphatase non-receptor type 1M-phase inducer phosphatase 2Proto-oncogene tyrosine-protein kinase Src +8

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S-Mercaptocysteine DB02761

small molecule | CAS: 5652-32-4

Deskripsi belum tersedia.

Target Protein:

Cysteine desulfuraseThiosulfate sulfurtransferase GlpEHydroxylamine reductase +6

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S-Methyl glutathione DB04701

small molecule | CAS: 2922-56-7

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsOligopeptidesPeptides

Target Protein:

Glutathione S-transferase Mu 2

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S-Methyl Phosphocysteine DB02461

small molecule

Deskripsi belum tersedia.

Target Protein:

Chemotaxis protein CheY

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S-Methyl Thiocysteine Group DB02361

small molecule

Deskripsi belum tersedia.

Target Protein:

Endoglucanase G

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S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE DB04720

small molecule

Deskripsi belum tersedia.

Target Protein:

Casein kinase II subunit alpha

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S-Methylcysteine DB02216

small molecule | CAS: 1187-84-4

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +4

Target Protein:

Cathepsin DMethylated-DNA--protein-cysteine methyltransferase

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S-octylglutathione DB03032

small molecule

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsGlutathione Transferase, antagonists & inhibitorsOligopeptides +1

Target Protein:

Glutathione S-transferase Mu 4

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S-oxy-L-cysteine DB03382

small molecule

Deskripsi belum tersedia.

Target Protein:

Aspartate 1-decarboxylaseProlyl endopeptidaseExopolyphosphatase +4

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S-palmitoyl-L-cysteine DB08342

small molecule | CAS: 114507-35-6

Deskripsi belum tersedia.

Target Protein:

Trafficking protein particle complex subunit 6ATrafficking protein particle complex subunit 3Trafficking protein particle complex subunit 6B +3

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S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate DB08217

small molecule

Deskripsi belum tersedia.

Target Protein:

Eukaryotic translation initiation factor 4EPossible exported proteinCell adhesion molecule CEACAM5 +1

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S-[(1-Hydroxy-2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate DB08456

small molecule

Deskripsi belum tersedia.

Target Protein:

Endolysin

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S-[(2E)-3,7-DIMETHYLOCTA-2,6-DIENYL] TRIHYDROGENTHIODIPHOSPHATE DB04702

small molecule

Deskripsi belum tersedia.

Target Protein:

Prenyltransferase

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S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate DB08585

small molecule

Deskripsi belum tersedia.

Target Protein:

Actinorhodin polyketide synthase acyl carrier protein

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S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate DB08586

small molecule

Deskripsi belum tersedia.

Target Protein:

Actinorhodin polyketide synthase acyl carrier protein

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S-[5-(TRIFLUOROMETHYL)-4H-1,2,4-TRIAZOL-3-YL] 5-(PHENYLETHYNYL)FURAN-2-CARBOTHIOATE DB07743

small molecule

Deskripsi belum tersedia.

Target Protein:

Replicase polyprotein 1abReplicase polyprotein 1a

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S-{2-[(2-chloro-4-sulfamoylphenyl)amino]-2-oxoethyl} 6-methyl-3,4-dihydroquinoline-1(2H)-carbothioate DB08494

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyprotein

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S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine DB02689

small molecule

Deskripsi belum tersedia.

Target Protein:

Arginase-1

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S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE DB07602

small molecule

Deskripsi belum tersedia.

Target Protein:

Epidermal growth factor receptor

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S64315 DB17559

small molecule | CAS: 1799631-75-6

S64315 (MIK665) is an inhibitor of induced myeloid leukemia cell differentiation protein Myeloid cell leukemia 1 (Mcl-1).[A257311]

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S65487 DB17556

small molecule | CAS: 1644600-79-2

S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.

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SAB-185 DB16491

biotech

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +7

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Sabarubicin DB12410

small molecule | CAS: 211100-13-9

Sabarubicin has been used in trials studying the treatment of Prostate Cancer, Testicular Germ Cell Tumor, and Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:

AnthracyclinesCarbohydratesGlycosides +3

Target Protein:

DNA topoisomerase 2-alphaDNA topoisomerase 2-beta

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Sabatolimab DB16322

biotech | CAS: 2252262-24-9

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesAntineoplastic Agents +8

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Sabestomig DB19326

biotech | CAS: 2648346-74-9

Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).

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Sabirnetug DB19438

biotech | CAS: 2747959-38-0

Sabirnetug is under investigation in clinical trial NCT06335173 (A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)).

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Saccharide isomerate Approved DB11232

small molecule | CAS: 100843-69-4

Deskripsi belum tersedia.

Kategori:

BiopolymersCarbohydratesMacromolecular Substances +2

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Saccharin DB12418

small molecule | CAS: 81-07-2

Saccharin has been investigated for the treatment of Hypertension and Hyperglycemia.

Kategori:

BenzothiazolesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +9

Target Protein:

Carbonic anhydrase 1Carbonic anhydrase 9Carbonic anhydrase 12 +2

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Sacituzumab govitecan Approved DB12893

biotech | CAS: 1491917-83-9

Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents.[A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a re…

Kategori:

AlkaloidsAmino Acids, Peptides, and ProteinsAntibodies +20

Target Protein:

Tumor-associated calcium signal transducer 2DNA topoisomerase 1Far upstream element-binding protein 1

Waktu ParuhSacituzumab govitec…

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Genetik -

Sacituzumab tirumotecan DB18777

biotech | CAS: 2768350-77-0

Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.

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