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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

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Hasil Pencarian (13591)

Halaman 236 / 272
Sodium apolate DB13477
small molecule | CAS: 25053-27-4

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAlkenes +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium ascorbate Approved DB14482
small molecule | CAS: 134-03-2

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAntioxidantsBiological Factors +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium aurotiosulfate Approved DB13743
small molecule | CAS: 33614-49-2

Deskripsi belum tersedia.

Kategori:
Antiinflammatory and Antirheumatic ProductsGold PreparationsLaxatives +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium bicarbonate Approved DB01390
small molecule | CAS: 144-55-8

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Kategori:
AntacidsAntacids and AdsorbentsBicarbonates +13
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1HA-type voltage-gated potassium channel KCND3Hydrogen ions
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium bisulfite Approved DB14015
small molecule | CAS: 7631-90-5

Sodium bisulfite has been used externally for parasitic skin diseases and as a gastrointestinal antiseptic.

Kategori:
AnionsAnti-Infective AgentsAnti-Infective Agents, Local +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium borate Approved DB14505
small molecule | CAS: 1330-43-4

Deskripsi belum tersedia.

Kategori:
AnionsAnti-Infective AgentsBoric Acids +5
Waktu ParuhAccording to human …
Vol. DistribusiVolume of distribut…
KlirensA case report of ac…
Genetik -
Sodium cation DB14516
small molecule | CAS: 17341-25-2

Deskripsi belum tersedia.

Kategori:
Increased Large Intestinal MotilityInhibition Large Intestine Fluid/Electrolyte AbsorptionLaxatives +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium cellulose phosphate Approved DB06776
small molecule | CAS: 9038-41-9

Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. [A31694] This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intesti…

Kategori:
BiopolymersCalcium BinderCalcium Chelating Activity +8
Target Protein:
Calcium ions
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium chloride Approved DB09153
small molecule | CAS: 7647-14-5

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid o…

Kategori:
Alimentary Tract and MetabolismBlood and Blood Forming OrgansBlood Substitutes and Perfusion Solutions +14
Waktu Paruh17 minutes
Vol. DistribusiThe volume of distr…
Klirens-
Genetik -
Sodium chlorite DB13210
small molecule | CAS: 7758-19-2

Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, …

Kategori:
AnionsChlorine CompoundsCicatrizants +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium chromate Cr-51 Approved DB09380
small molecule | CAS: 10039-53-9

Deskripsi belum tersedia.

Kategori:
Radioactive Diagnostic Agent
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium feredetate Approved DB13381
small molecule | CAS: 15708-41-5

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAmines +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 34089-81-1

Sodium ferric gluconate complex is an iron replacement product for treatment of iron deficiency anemia. The stable macromolecular complex is negatively charged at alkaline pH with an apparent molecular weight of 289,000 – 440,000 daltons on gel chromatography…

Kategori:
Iron PreparationsParenteral Iron Replacement
Target Protein:
Ferritin light chainHemoglobin subunit betaHemoglobin subunit alpha
Waktu ParuhThe terminal elimin…
Vol. DistribusiUsing single-dose p…
KlirensTotal clearance ran…
Genetik -
Sodium fluoride Approved DB09325
small molecule | CAS: 7681-49-4

Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18].[L4894] Sodium fluoride's benefits on dental health were first o…

Kategori:
Alimentary Tract and MetabolismAnionsCaries Prophylactic Agents +13
Target Protein:
Hydroxyapatite
Waktu ParuhThe terminal plasma…
Vol. DistribusiFluoride distribute…
KlirensSodium fluoride is …
Genetik -
Sodium fluorophosphate Approved DB09484
small molecule | CAS: 10163-15-2

Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.

Kategori:
AcidsAcids, NoncarboxylicAlimentary Tract and Metabolism +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium glycerophosphate Approved DB09561
small molecule | CAS: 1334-74-3

Sodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. The extent of this reaction …

Kategori:
AlcoholsBlood and Blood Forming OrgansBlood Substitutes and Perfusion Solutions +10
Waktu ParuhInorganic phosphate…
Vol. Distribusi-
Klirens-
Genetik -
Sodium hydroxide Approved DB11151
small molecule | CAS: 1310-73-2

Sodium hydroxide is also known as _lye_ or _soda_ , or _caustic soda_ [L1971]. At room temperature, sodium hydroxide is a white crystalline odorless solid that absorbs moisture from the air. It is a synthetically manufactured substance. When dissolved in w…

Kategori:
AlkaliesAnionsCaustics +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium iodide Approved DB11119
small molecule | CAS: 7681-82-5

Sodium iodide is a water-soluble ionic compound with a crystal lattice. Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine. Radiolabelled compound…

Kategori:
IodidesIodine CompoundsReplacement Preparations +2
Waktu Paruh-
Vol. DistribusiIodides are distrib…
Klirens-
Genetik -
small molecule | CAS: 151-21-3

Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. SLS lowers surface tension of aqueous solutions and is used as fat emulsi…

Kategori:
AlcoholsAlkanesulfonatesAlkanesulfonic Acids +9
Target Protein:
Albumin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium lauryl sulfoacetate Approved DB13157
small molecule | CAS: 1847-58-1

Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.

Kategori:
Alimentary Tract and MetabolismDrugs for ConstipationEnemas
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium metavanadate Approved DB14702
small molecule | CAS: 13718-26-8

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesIons +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium molybdate Approved DB14496
small molecule | CAS: 7631-95-0

Deskripsi belum tersedia.

Kategori:
ElementsMetalsMetals, Heavy +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium nitrate DB15952
small molecule | CAS: 7631-99-4

Deskripsi belum tersedia.

Kategori:
AnionsCarcinogensElectrolytes +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium oxybate Approved DB09072
small molecule | CAS: 502-85-2

Sodium oxybate (Xyrem) is a central nervous system (CNS) depressant used to treat cataplexy or excessive daytime sleepiness associated with narcolepsy.[L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmit…

Kategori:
Acids, AcyclicAdjuvants, AnesthesiaAnesthetics +9
Target Protein:
GABA(B) ReceptorSolute carrier family 52, riboflavin transporter, member 2
Waktu ParuhGHB has an eliminat…
Vol. DistribusiThe apparent volume…
KlirensIn healthy GHB-naïv…
Genetik -
Sodium phosphate P 32 Approved DB09370
small molecule | CAS: 7635-46-3

Deskripsi belum tersedia.

Kategori:
Antineoplastic AgentsDiagnostic AgentsNarrow Therapeutic Index Drugs +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium phosphate, monobasic Approved DB09449
small molecule | CAS: 7558-80-7

Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.

Kategori:
AcidsAcids, NoncarboxylicAgents that reduce seizure threshold +19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
LaxativesOsmotic Laxatives
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Sodium stibogluconate Approved DB05630
small molecule | CAS: 16037-91-5

Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufacture…

Kategori:
Acids, AcyclicAgents Against Leishmaniasis and TrypanosomiasisAnti-Infective Agents +10
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium sulfide Approved DB11159
small molecule | CAS: 1313-82-2

Sodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes including the production of rubber chemicals, sulfur dye…

Kategori:
AnionsElectrolytesHydrogen Sulfide +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium tartrate Approved DB13707
small molecule | CAS: 868-18-8

Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food…

Kategori:
Acids, AcyclicAlimentary Tract and MetabolismCarbohydrates +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium tetradecyl sulfate Approved DB00464
small molecule | CAS: 139-88-8

An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.

Kategori:
AcidsAlcoholsAlkanesulfonates +16
Target Protein:
Vitamin K-dependent protein SVitamin K-dependent protein C
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7758-29-4

Sodium tripolyphosphate is an inorganic compound with formula Na5P3O10 and the sodium salt of the polyphosphate penta-anion. It is used as a component of a wide range domestic and industrial products, particularly detergents.

Kategori:
AcidsAcids, NoncarboxylicAnions +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 17141-74-1

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent.[L2933…

Kategori:
AcidsAcids, NoncarboxylicAnions +13
Target Protein:
Potassium
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 1418200-58-4

Sofituzumab vedotin is under investigation in clinical trial NCT01335958 (Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sofosbuvir Approved DB08934
small molecule | CAS: 1190307-88-0

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is c…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +18
Target Protein:
Genome polyproteinRNA-dependent RNA-polymerase
Waktu ParuhSofosbuvir has a te…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of so…
Genetik -
Sofpironium Approved DB19325
small molecule | CAS: 1628251-49-9

Sofpironium is a "soft" anticholinergic analog of [glycopyrronium] that has been modified with a readily hydrolyzable ester moiety.[L51109] Soft drugs are designed to reduce systemic toxicity while enhancing local efficacy by employing retrometabolic drug des…

Kategori:
Anticholinergic AgentsCytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (strength unknown) +13
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor
Waktu ParuhThe _in vitro_ half…
Vol. Distribusi-
Klirens-
Genetik -
Solabegron DB06190
small molecule | CAS: 252920-94-8

Solabegron (GW-427,353) is a selective ?3 adrenoceptor agonist being developed for the treatment of overactive bladder and irritable bowel syndrome.

Kategori:
Acids, CarbocyclicAdrenergic AgentsAdrenergic Agonists +8
Target Protein:
Beta-3 adrenergic receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solamargine DB12700
small molecule | CAS: 20311-51-7

Solamargine has been used in trials studying the treatment of Actinic Keratosis.

Kategori:
Alkaloids
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solanezumab DB11756
biotech | CAS: 955085-14-0

Solanezumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers Disease, Familial.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solasodine DB18813
small molecule | CAS: 126-17-0

Deskripsi belum tersedia.

Kategori:
Alkaloids
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solasonine DB17103
small molecule | CAS: 19121-58-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsStereoisomerism
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solifenacin Approved DB01591
small molecule | CAS: 242478-37-1

Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.[L7511] It has a long duration of action as it is usually taken once daily.[L7511] Solifenacin was grante…

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAnticholinergic Agents +19
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M4 +2
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of so…
Genetik -
Solithromycin DB09308
small molecule | CAS: 760981-83-7

Solithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntibacterials for Systemic Use +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solnatide DB12136
biotech | CAS: 259206-53-6

Solnatide has been used in trials studying the treatment of Acute Lung Injury.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solriamfetol Approved DB14754
small molecule | CAS: 178429-62-4

Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with narcolepsy or obstructive sleep apnea[FDA Label]…

Kategori:
Acids, AcyclicAdrenergic AgentsAdrenergic Uptake Inhibitors +22
Target Protein:
Sodium-dependent dopamine transporterSodium-dependent noradrenaline transporter
Waktu Paruh7.1 hours[FDA Label…
Vol. Distribusi199L[FDA Label]. Ot…
KlirensRenal clearance is …
Genetik -
Solrikitug DB19301
biotech | CAS: 2768721-24-8

Solrikitug is under investigation in clinical trial NCT06496607 (A Study to Evaluate Solriktug in Adult Participants With Asthma).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Somapacitan Approved DB15093
biotech | CAS: 1338578-34-9

Somapacitan, also known as NNC0195-0092,[A219136] is a growth hormone analog indicated to treat adults with growth hormone deficiency.[A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effe…

Kategori:
AlcoholsAmino AcidsAmino Acids, Cyclic +25
Target Protein:
Growth hormone receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThe approximate vol…
KlirensThe apparent maximu…
Genetik -
Somatorelin DB12656
biotech | CAS: 83930-13-6

Somatorelin has been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and Mild Cognitive Impairment.

Kategori:
Amino Acids, Peptides, and ProteinsDiagnostic AgentsGrowth Hormone-Releasing Hormone, agonists +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Somatostatin Approved DB09099
small molecule | CAS: 38916-34-6

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues [T28] that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin an…

Kategori:
Amino Acids, Peptides, and ProteinsCytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A4 Inhibitors +17
Target Protein:
Mu-type opioid receptorDelta-type opioid receptorSomatostatin receptor type 1 +4
Waktu ParuhThe half-life of en…
Vol. DistribusiThis pharmacokineti…
KlirensFollowing intraveno…
Genetik -
Somatotropin Approved DB00052
biotech | CAS: 12629-01-5

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland.[A228183] Growth hormone plays an essential role in growth regulation during childhood as w…

Kategori:
Agents Causing Muscle ToxicityAmino Acids, Peptides, and ProteinsAnterior Pituitary Lobe Hormones and Analogues +23
Target Protein:
Growth hormone receptorProlactin receptor
Waktu ParuhWhen somatotropin w…
Vol. DistribusiInformation is unav…
KlirensFollowing intraveno…
Genetik -
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