Digital Pharmacy - Dashboard Peneliti

RU82197 DB03268

small molecule

Deskripsi belum tersedia.

Target Protein:

Proto-oncogene tyrosine-protein kinase Src

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RU82209 DB03591

small molecule

Deskripsi belum tersedia.

Target Protein:

Proto-oncogene tyrosine-protein kinase Src

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RU83876 DB02336

small molecule

Deskripsi belum tersedia.

Target Protein:

Proto-oncogene tyrosine-protein kinase Src

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RU84687 DB01678

small molecule

RU84687 is a subnanomolar and Src SH2 selective binder.

Target Protein:

Proto-oncogene tyrosine-protein kinase Src

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RU85053 DB03712

small molecule

Deskripsi belum tersedia.

Target Protein:

Proto-oncogene tyrosine-protein kinase Src

Waktu Paruh-

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RU90395 DB02432

small molecule

Deskripsi belum tersedia.

Target Protein:

Proto-oncogene tyrosine-protein kinase Src

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Rubella virus vaccine Approved DB10317

biotech

Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, …

Kategori:

Actively Acquired ImmunityAntiinfectives for Systemic UseLive Attenuated Rubella Virus Vaccine +5

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Rubidium Rb-82 Approved DB09479

small molecule

Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial p…

Kategori:

Radioactive Diagnostic AgentRadiopharmaceutical Activity

Waktu Paruh1.27 minutes

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Rubitecan DB06159

small molecule | CAS: 91421-42-0

Deskripsi belum tersedia.

Kategori:

AlkaloidsAntineoplastic AgentsEnzyme Inhibitors +2

Target Protein:

DNA topoisomerase 1

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Ruboxistaurin DB11829

small molecule | CAS: 169939-94-0

Ruboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus.

Kategori:

Acids, AcyclicDicarboxylic AcidsEnzyme Inhibitors +4

Target Protein:

Peptide deformylase, mitochondrialProtein kinase C beta type

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Rucaparib Approved DB12332

small molecule | CAS: 283173-50-2

Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair.[A18745] Rucaparib is proposed to work in several PARP-dependent and PARP-independent mechanisms of action; however…

Kategori:

Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Inhibitors +47

Target Protein:

Poly [ADP-ribose] polymerase 1Poly [ADP-ribose] polymerase 2Protein mono-ADP-ribosyltransferase PARP3

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Rufinamide Approved DB06201

small molecule | CAS: 106308-44-5

Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.

Kategori:

AnticonvulsantsCarboxamide DerivativesCardiovascular Agents +14

Target Protein:

Sodium channel protein type 9 subunit alphaMetabotropic glutamate receptor 5

Waktu ParuhElimination half-li…

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Rufloxacin DB13772

small molecule | CAS: 101363-10-4

Rufloxacin is a quinolone antibiotic. [A31894]

Kategori:

4-QuinolonesAnti-Bacterial AgentsAntibacterials for Systemic Use +13

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Rugonersen DB18662

biotech | CAS: 2591587-57-2

Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of Angelman Syndrome.

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Rulonilimab DB18922

biotech | CAS: 2417124-95-7

Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma).

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Rumex crispus whole Approved DB14267

biotech

Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Rumex salicifolius var. mexicanus pollen Approved DB10902

biotech

Rumex salicifolius var. mexicanus pollen is the pollen of the Rumex salicifolius var. mexicanus plant. Rumex salicifolius var. mexicanus pollen is mainly used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1

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Runcaciguat DB16700

small molecule | CAS: 1402936-61-1

Deskripsi belum tersedia.

Kategori:

Benzene DerivativesCycloparaffins

Target Protein:

Guanylate cyclase soluble subunit alpha-1Guanylate cyclase soluble subunit beta-1

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Rupatadine Approved DB11614

small molecule | CAS: 158876-82-5

Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tr…

Kategori:

Antihistamines for Systemic UseBenzocycloheptenesCytochrome P-450 CYP2C19 Substrates +13

Target Protein:

Platelet-activating factor receptorHistamine H1 receptor

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Genetik -

Rupintrivir DB05102

small molecule | CAS: 223537-30-2

Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV) infections. Rupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells. It is designed to combat colds caused b…

Kategori:

Amino AcidsAmino Acids, AromaticAmino Acids, Branched-Chain +8

Target Protein:

Genome polyproteinGenome polyprotein

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Ruplizumab DB06475

biotech | CAS: 220651-94-5

Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.

Kategori:

Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +4

Target Protein:

CD40 ligand

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Rurioctocog alfa pegol Approved DB16007

biotech | CAS: 1417412-83-9

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated r…

Kategori:

Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +9

Target Protein:

von Willebrand factorCoagulation factor VIII

Waktu ParuhFollowing intraveno…

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Genetik -

Rusalatide acetate DB11668

biotech | CAS: 875455-82-6

Chrysalin has been used in trials studying the treatment of Radius Fracture.

Kategori:

Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +11

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Ruscogenin DB15830

small molecule | CAS: 472-11-7

Deskripsi belum tersedia.

Kategori:

CholestanesFused-Ring CompoundsSapogenins +1

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Rusfertide DB17724

biotech | CAS: 1628323-80-7

Rusfertide is a hepcidin mimetic currently being developed by Protagonist Therapeutics for the treatment of polycythemia vera and beta-thalassemia.

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Rutin Approved DB01698

small molecule | CAS: 153-18-4

A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.

Kategori:

BenzopyransCapillary Stabilizing AgentsChromones +12

Target Protein:

Aldo-keto reductase family 1 member C3Carbonyl reductase [NADPH] 1

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RUTI® Vaccine DB15853

biotech

The RUTI® Vaccine contains fragmented, purified and liposomed heat-inactivated Mycobacterium tuberculosis bacilli. The vaccine has demonstrated a reasonable safety profile and potent stimulation of the immune response against tuberculosis. Much like the BCG v…

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Ruxolitinib Approved DB08877

small molecule | CAS: 941678-49-5

Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved in cytokine signalling and hematopoiesis.[A745…

Kategori:

Agents for Dermatitis, Excluding CorticosteroidsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +18

Target Protein:

Urokinase plasminogen activator surface receptorTyrosine-protein kinase JAK2Tyrosine-protein kinase JAK1 +2

Waktu ParuhThe mean eliminatio…

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Genetik -

Ruzinurad DB19209

small molecule | CAS: 1638327-48-6

Ruzinurad is under investigation in clinical trial NCT04956432 (A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout).

Kategori:

CycloparaffinsHeterocyclic Compounds, Fused-Ring

Target Protein:

Solute carrier family 22 member 12

Waktu Paruh-

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RWJ-51084 DB03251

small molecule

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, BasicAmino Acids, Diamino +4

Target Protein:

Serine protease 1

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RWJ-56423 DB02812

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine protease 1

Waktu Paruh-

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RWJ-800088 DB18693

biotech | CAS: 257287-15-3

RWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous TPO.

Kategori:

Amino Acids, Peptides, and ProteinsBiological FactorsPeptides +2

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S,R-Warfarin alcohol DB08736

small molecule | CAS: 40281-79-6

Deskripsi belum tersedia.

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S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea DB03910

small molecule

Deskripsi belum tersedia.

Target Protein:

Nitric oxide synthase, inducibleNitric oxide synthase 3

Waktu Paruh-

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S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea DB02141

small molecule

Deskripsi belum tersedia.

Target Protein:

Nitric oxide synthase 3

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S,S-(2-Hydroxyethyl)Thiocysteine DB04530

small molecule

Deskripsi belum tersedia.

Target Protein:

Thymidylate synthaseDelta-aminolevulinic acid dehydratase3',5'-cyclic-AMP phosphodiesterase 4B +15

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S-(2,4-dinitrophenyl)glutathione DB02458

small molecule | CAS: 26289-39-4

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsHaptensOligopeptides +1

Target Protein:

Glutathione S-transferase Mu 1Glutathione S-transferase Mu 2

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S-(2-Acetamidoethyl) hexadecanethioate DB02990

small molecule

Deskripsi belum tersedia.

Target Protein:

Enoyl-[acyl-carrier-protein] reductase [NADH]

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S-(2-oxo)pentadecylcoa DB02271

small molecule

Deskripsi belum tersedia.

Target Protein:

Glycylpeptide N-tetradecanoyltransferase 2

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S-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) HEPTANETHIOATE DB08405

small molecule

Deskripsi belum tersedia.

Target Protein:

Acyl carrier protein

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S-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) HEXANETHIOATE DB08404

small molecule

Deskripsi belum tersedia.

Target Protein:

Acyl carrier protein

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S-(D-Carboxybutyl)-L-Homocysteine DB02337

small molecule

Deskripsi belum tersedia.

Target Protein:

Betaine--homocysteine S-methyltransferase 1

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S-(Methylmercury)-L-Cysteine DB02750

small molecule

Deskripsi belum tersedia.

Target Protein:

Elongation factor-like GTPase 1

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S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione DB03889

small molecule

Deskripsi belum tersedia.

Kategori:

Amino Acids, Peptides, and ProteinsOligopeptidesPeptides

Target Protein:

Hydroxyacylglutathione hydrolase, mitochondrial

Waktu Paruh-

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S-(N-hydroxy-N-iodophenylcarbamoyl)glutathione DB03330

small molecule

Deskripsi belum tersedia.

Target Protein:

Lactoylglutathione lyase

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S-2-(Boronoethyl)-L-Cysteine DB03731

small molecule

Deskripsi belum tersedia.

Target Protein:

Arginase-1Arginase-2, mitochondrial

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S-23 DB07419

small molecule | CAS: 1010396-29-8

An androgen receptor modulator.

Kategori:

AmidesAminesAniline Compounds +2

Target Protein:

Androgen receptor

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S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE DB07769

small molecule

Deskripsi belum tersedia.

Target Protein:

Androgen receptor

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S-3304 DB12149

small molecule | CAS: 203640-27-1

S-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non Small Cell Lung Cancer, among others.

Kategori:

Enzyme InhibitorsHeterocyclic Compounds, Fused-RingMatrix Metalloproteinase Inhibitors +2

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S-38093 DB16893

small molecule | CAS: 862896-30-8

Deskripsi belum tersedia.

Kategori:

Acids, CarbocyclicAmidesAza Compounds +2

Target Protein:

Histamine H3 receptor

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Genetik -

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