Digital Pharmacy - Dashboard Peneliti

N~2~-1,3-BENZOXAZOL-2-YL-3-CYCLOHEXYL-N-{2-[(4-METHOXYPHENYL)AMINO]ETHYL}-L-ALANINAMIDE DB07839

small molecule

Deskripsi belum tersedia.

Target Protein:

Cathepsin S

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N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine DB07382

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine/threonine-protein kinase/endoribonuclease IRE1

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N~2~-Succinylornithine DB03582

small molecule

Deskripsi belum tersedia.

Target Protein:

N-succinylarginine dihydrolase

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N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE DB07571

small molecule

Deskripsi belum tersedia.

Target Protein:

ATP-dependent Clp protease proteolytic subunit

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N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE DB07284

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~3~-BENZYLPYRIDINE-2,3-DIAMINE DB07281

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide DB07835

small molecule

Deskripsi belum tersedia.

Target Protein:

Mitogen-activated protein kinase 14

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N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE DB07993

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~3~-[3-(5-METHOXYPYRIDIN-3-YL)BENZYL]PYRIDINE-2,3-DIAMINE DB07303

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~3~-[5-(1H-INDOL-6-YL)-2-(PYRIDIN-2-YLMETHOXY)BENZYL]PYRIDINE-2,3-DIAMINE DB07994

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-secretase 1

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N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine DB08519

small molecule

Deskripsi belum tersedia.

Target Protein:

Vascular endothelial growth factor receptor 2

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N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine DB08042

small molecule

Deskripsi belum tersedia.

Target Protein:

Vascular endothelial growth factor receptor 2

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O,O-DIETHYL HYDROGEN THIOPHOSPHATE DB07674

small molecule

Deskripsi belum tersedia.

Target Protein:

Phosphotriesterase

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O-(((1R)-((N-(PHENYL-METHOXY-CARBONYL)-ALANYL)-AMINO)METHYL)HYDROXYPHOSPHINYL)3-L-PHENYLLACTATE DB07351

small molecule

Deskripsi belum tersedia.

Target Protein:

Carboxypeptidase A1

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O-(((1R)-((N-PHENYLMETHOXYCARBONYL-L-ALANYL)AMINO)ETHYL)HYDROXYPHOSPHONO)-L-BENZYLACETIC ACID DB08762

small molecule

Deskripsi belum tersedia.

Target Protein:

Carboxypeptidase A1

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O-(N-acetyl-alpha-D-galactosaminyl)-L-serine DB02397

small molecule | CAS: 67262-86-6

Deskripsi belum tersedia.

Kategori:

AntigensAntigens, NeoplasmBiological Factors +3

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O-acetyl-L-serine DB01837

small molecule | CAS: 5147-00-2

Deskripsi belum tersedia.

Target Protein:

Prostaglandin G/H synthase 1

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O-Benzylsulfonyl-Serine DB01973

small molecule

Deskripsi belum tersedia.

Target Protein:

Capsid scaffolding proteinSubtilisin SavinaseTrypsin-2 +2

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o-Bromophenol DB04586

small molecule | CAS: 95-56-7

Deskripsi belum tersedia.

Kategori:

Benzene Derivatives

Target Protein:

Thymidylate synthaseThymidylate synthase

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o-Cymen-5-ol DB15901

small molecule | CAS: 3228-02-2

Deskripsi belum tersedia.

Kategori:

Benzene Derivatives

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O-Decyl Hydrogen Thiocarbonate DB08684

small molecule

Deskripsi belum tersedia.

Target Protein:

3-oxoacyl-[acyl-carrier-protein] synthase 3

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O-Succinylbenzoate DB02251

small molecule | CAS: 27415-09-4

Deskripsi belum tersedia.

Kategori:

Acids, Carbocyclic

Target Protein:

o-succinylbenzoate synthaseo-succinylbenzoate synthaseo-succinylbenzoate synthase

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O-Trifluoromethylphenyl Anthranilic Acid DB02179

small molecule

Deskripsi belum tersedia.

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O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-bromophenyl)thiocarbamate DB08281

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyprotein

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O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-chlorophenyl)thiocarbamate DB08282

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyprotein

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O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-iodophenyl)thiocarbamate DB08284

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyprotein

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O1-Methyl-4-Deoxy-4-Thio-Alpha-D-Glucose DB03406

small molecule

Deskripsi belum tersedia.

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O1-Pentyl-Mannose DB02695

small molecule

Deskripsi belum tersedia.

Target Protein:

Cyanovirin-N

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O2-Sulfo-Glucuronic Acid DB02264

small molecule

Deskripsi belum tersedia.

Target Protein:

Fibroblast growth factor 1Hepatocyte growth factorHeparan sulfate glucosamine 3-O-sulfotransferase 3A1 +1

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O3-Sulfonylgalactose DB01818

small molecule

Deskripsi belum tersedia.

Target Protein:

Mannose-binding protein C

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O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL DB04770

small molecule

Deskripsi belum tersedia.

Target Protein:

Pyridoxal kinase

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O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE DB07126

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine/threonine-protein kinase Chk1Glycogen synthase kinase-3 betaCyclin-dependent kinase 4 +2

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OAV201 DB17842

biotech

OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter. It was first developed by Novartis and investigated…

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Obatoclax DB12191

small molecule | CAS: 803712-67-6

Obatoclax has been used in trials studying the treatment of AML, Leukemia, Myelofibrosis, Hodgkin's Lymphoma, and Mantle-Cell Lymphoma, among others.

Kategori:

Enzyme InhibitorsHeterocyclic Compounds, Fused-Ring

Target Protein:

Apoptosis regulator Bcl-2Induced myeloid leukemia cell differentiation protein Mcl-1Bcl-2-like protein 1

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Obecabtagene autoleucel Approved DB17362

biotech

Obecabtagene autoleucel is an investigational autologous CD19 CAR T cell therapy.

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Obeldesivir DB18821

small molecule | CAS: 2647441-36-7

Deskripsi belum tersedia.

Kategori:

Adenine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4

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Obeticholic acid Approved DB05990

small molecule | CAS: 459789-99-2

Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation.[A192786] Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to…

Kategori:

Alimentary Tract and MetabolismBile Acid PreparationsBile acids and derivatives +14

Target Protein:

Bile acid receptor

Waktu ParuhThe biological half…

Vol. DistribusiThe volume of distr…

KlirensClearance informati…

Genetik -

Obexelimab DB15032

biotech | CAS: 1690307-05-1

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).

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OBI-3424 DB16057

small molecule | CAS: 2097713-68-1

OBI-3424 is under investigation in clinical trial NCT04315324 (Study to Test Akr1c3-activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/refractory T-cell Acute Lymphoblastic Leukemia (T-ALL)).

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OBI-833 DB19270

biotech | CAS: 2142641-90-3

Deskripsi belum tersedia.

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OBI-888 DB18289

biotech | CAS: 2227156-40-1

Deskripsi belum tersedia.

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OBI-999 DB17356

biotech

Deskripsi belum tersedia.

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Obicetrapib DB14890

small molecule | CAS: 866399-87-3

Obicetrapib is under investigation in clinical trial NCT02241772 (A Study on the Effects of TA-8995 on Lp(a) in Subjects With Elevated Lp(a)).

Kategori:

Heterocyclic Compounds, Fused-Ring

Target Protein:

Cholesteryl ester transfer protein

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Obidoxime DB13750

small molecule | CAS: 7683-36-5

Deskripsi belum tersedia.

Kategori:

AminesAntidotesCholinergic Agents +7

Target Protein:

Acetylcholinesterase

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Obiltoxaximab Approved DB05336

biotech | CAS: 1351337-07-9

Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin. Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis to…

Kategori:

Amino Acids, Peptides, and ProteinsAnthrax Protective Antigen-directed AntibodyAnthrax Protective Antigen-directed Antibody Interactions +15

Target Protein:

Protective antigen

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Obinepitide DB05045

small molecule | CAS: 348119-84-6

Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from t…

Target Protein:

Neuropeptide Y receptor type 4Neuropeptide Y receptor type 2

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Obinutuzumab Approved DB08935

biotech | CAS: 949142-50-1

Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is …

Kategori:

Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +20

Target Protein:

B-lymphocyte antigen CD20

Waktu ParuhThe half life of ob…

Vol. DistribusiObinutuzumab has a …

KlirensThe clearance of ob…

Genetik -

Oblimersen DB13811

small molecule | CAS: 190977-41-4

Deskripsi belum tersedia.

Kategori:

Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsAntisense Elements (Genetics) +13

Target Protein:

Apoptosis regulator Bcl-2

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OBP-801 DB12279

small molecule | CAS: 328548-11-4

OBP-801 has been used in trials studying the treatment of Solid Tumor.

Kategori:

Amino Acids, Peptides, and ProteinsAntineoplastic AgentsHistone Deacetylase Inhibitors +2

Target Protein:

Histone deacetylase 1

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OC-1012 DB05834

small molecule

OC-1012 is a compound which has emerged as a promising therapeutic agent for the treatment and prevention of mucositis, a serious side effect of chemotherapy and head and neck radiation therapy.

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