Hasil Filter

13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (13591)

Halaman 228 / 272
Rumex crispus pollen Approved DB10360
biotech

Rumex crispus pollen is the pollen of the Rumex crispus plant. Rumex crispus pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Runcaciguat DB16700
small molecule | CAS: 1402936-61-1

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesCycloparaffins
Target Protein:
Guanylate cyclase soluble subunit alpha-1Guanylate cyclase soluble subunit beta-1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rupintrivir DB05102
small molecule | CAS: 223537-30-2

Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV) infections. Rupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells. It is designed to combat colds caused b…

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Branched-Chain +8
Target Protein:
Genome polyproteinGenome polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rurioctocog alfa pegol Approved DB16007
biotech | CAS: 1417412-83-9

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated r…

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +9
Target Protein:
von Willebrand factorCoagulation factor VIII
Waktu ParuhFollowing intraveno…
Vol. DistribusiFollowing intraveno…
KlirensFollowing intraveno…
Genetik -
RUS 3108 DB05911
small molecule

RUS 3108 is being developed for the treatment of atherosclerosis, the major cause of cardiovascular disorders such as heart attacks and stroke by Dr. Reddy’s Laboratories. The drug’s Phase I clinical trials have been initiated in Europe to assess safety of …

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ruscogenin DB15830
small molecule | CAS: 472-11-7

Deskripsi belum tersedia.

Kategori:
CholestanesFused-Ring CompoundsSapogenins +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rusfertide DB17724
biotech | CAS: 1628323-80-7

Rusfertide is a hepcidin mimetic currently being developed by Protagonist Therapeutics for the treatment of polycythemia vera and beta-thalassemia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Rutin Approved DB01698
small molecule | CAS: 153-18-4

A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.

Kategori:
BenzopyransCapillary Stabilizing AgentsChromones +12
Target Protein:
Aldo-keto reductase family 1 member C3Carbonyl reductase [NADPH] 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RUTI® Vaccine DB15853
biotech

The RUTI® Vaccine contains fragmented, purified and liposomed heat-inactivated Mycobacterium tuberculosis bacilli. The vaccine has demonstrated a reasonable safety profile and potent stimulation of the immune response against tuberculosis. Much like the BCG v…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ruxolitinib Approved DB08877
small molecule | CAS: 941678-49-5

Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved in cytokine signalling and hematopoiesis.[A745…

Kategori:
Agents for Dermatitis, Excluding CorticosteroidsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +18
Target Protein:
Urokinase plasminogen activator surface receptorTyrosine-protein kinase JAK2Tyrosine-protein kinase JAK1 +2
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe mean volume of …
KlirensRuxolitinib clearan…
Genetik -
Ruzasvir DB11713
small molecule | CAS: 1613081-64-3

Ruzasvir has been used in trials studying the treatment of Hepatitis C, Hepatitis C, Chronic, and Hepatitis C Infection.

Kategori:
Anti-Infective AgentsAntiviral AgentsHeterocyclic Compounds, Fused-Ring +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ruzinurad DB19209
small molecule | CAS: 1638327-48-6

Ruzinurad is under investigation in clinical trial NCT04956432 (A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout).

Kategori:
CycloparaffinsHeterocyclic Compounds, Fused-Ring
Target Protein:
Solute carrier family 22 member 12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RVT-3101 DB18718
biotech

RVT-3101 is a fully human monoclonal antibody targeting vascular endothelial growth inhibitor, also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15. It is being investigated for ulcerative colitis.

Target Protein:
Tumor necrosis factor ligand superfamily member 15
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RWJ-51084 DB03251
small molecule

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +4
Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RWJ-56423 DB02812
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
RWJ-800088 DB18693
biotech | CAS: 257287-15-3

RWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous TPO.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsPeptides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 40281-79-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase, inducibleNitric oxide synthase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Thymidylate synthaseDelta-aminolevulinic acid dehydratase3',5'-cyclic-AMP phosphodiesterase 4B +15
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
ThermonucleaseListeriolysin regulatory protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 26289-39-4

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsHaptensOligopeptides +1
Target Protein:
Glutathione S-transferase Mu 1Glutathione S-transferase Mu 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Acyl carrier protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Acyl carrier protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glutathione S-transferase P
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6803-19-6

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsOligopeptidesPeptides
Target Protein:
Glutathione S-transferase P
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Betaine--homocysteine S-methyltransferase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Toll-like receptor 2Capsid scaffolding proteinGag-Pol polyprotein +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsOligopeptidesPeptides
Target Protein:
Hydroxyacylglutathione hydrolase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Lactoylglutathione lyase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Arginase-1Arginase-2, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-23 DB07419
small molecule | CAS: 1010396-29-8

An androgen receptor modulator.

Kategori:
AmidesAminesAniline Compounds +2
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-3304 DB12149
small molecule | CAS: 203640-27-1

S-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non Small Cell Lung Cancer, among others.

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-RingMatrix Metalloproteinase Inhibitors +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-38093 DB16893
small molecule | CAS: 862896-30-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesAza Compounds +2
Target Protein:
Histamine H3 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-3APG DB17419
small molecule

S-3APG (S-3-[3-amino-phthalimido]-glutarimide) is a derivative of thalidomide with dual activity against B-cell neoplasias.[A255168]

Kategori:
Acids, CarbocyclicHeterocyclic Compounds, Fused-RingIsoindoles +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glutaryl-CoA dehydrogenase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-40503 DB13938
small molecule | CAS: 404920-28-1

S-40503 is an investigational selective androgen receptor modulator (SARM) developed for the treatment of osteoporosis by the Japanese company Kaken Pharmaceuticals.

Kategori:
Heterocyclic Compounds, Fused-Ring
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-55746 DB18365
small molecule | CAS: 1448584-12-0

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingOxazines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-777469 DB16321
small molecule | CAS: 885496-53-7

S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis).

Kategori:
Pyridines
Target Protein:
Cannabinoid receptor 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-8510 DB06504
small molecule

S-8510 / SB-737552 is a BZD inverse agonist investigated for the treatment of Alzheimer’s disease and mild to moderate senile dementia. It was being codeveloped by Shionogi and GlaxoSmithKline.

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-Ring
Target Protein:
Translocator protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 14047-27-9

Deskripsi belum tersedia.

Target Protein:
Thymidine kinase, cytosolicThymidine kinaseAdenosine deaminase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Histone acetyltransferase KAT5Acetyl-CoA acetyltransferase3-oxoacyl-[acyl-carrier-protein] synthase 3 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 76426-40-9

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and NucleosidesNucleosides +3
Target Protein:
Polyamine aminopropyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 979-92-0

5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Sulfur +7
Target Protein:
DNA (cytosine-5)-methyltransferase 3BHistamine N-methyltransferaseCap-specific mRNA (nucleoside-2'-O-)-methyltransferase +34
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Selenium Compounds
Target Protein:
tRNA (cmo5U34)-methyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
S-Apomorphine DB16927
small molecule | CAS: 39478-62-1

Deskripsi belum tersedia.

Target Protein:
D(1A) dopamine receptorD(2) dopamine receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Arsenate reductaseProtein ArsC3-mercaptopyruvate sulfurtransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 3054-01-1

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +3
Target Protein:
Methylated-DNA--protein-cysteine methyltransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 11351–11400 dari 13591
Sebelumnya Halaman 228 / 272 Berikutnya