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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (15718)

Halaman 220 / 315
NV1020 DB04969
biotech

NV1020, a genetically engineered herpes simplex virus, is a novel anticancer therapeutic.

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NVD-001 DB18459
biotech

Deskripsi belum tersedia.

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NVL-655 DB18682
small molecule

NVL-655 is an orally bioavailable, brain-penetrant anaplastic lymphoma kinase (ALK) inhibitor inhibitor being investigated for the treatment of non-small cell lung cancer.

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NVP-LEQ-506 DB12857
small molecule | CAS: 1204975-42-7

LEQ506 has been used in trials studying the treatment of Advanced Solid Tumors, Recurrent or Refractory Medulloblastoma, and Locally Advanced or Metastatic Basal Cell Carcinoma.

Target Protein:
Protein smoothened
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NVS antibody DB05312
small molecule

This drug has been developed using Medarex's UltiMAb Human Antibody Development System to treat autoimmune diseases.

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NX-1207 DB05493
small molecule

NX-1207 is an investigational new drug for BPH, whose chemical entity and mechanism of action remain undisclosed. Nymox Pharmaceutical Corporation recently completed studies of NX-1207 for treatment of benign prostatic hyperplasia (BPH).

Kategori:
Amino Acids, Peptides, and Proteins
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NX-210c DB18209
biotech | CAS: 216682-41-6

Deskripsi belum tersedia.

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NX001 DB18099
biotech

Deskripsi belum tersedia.

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NXC680 DB18366
small molecule

NXC680 is a small molecule under investigation for the treatment of idiopathic pulmonary fibrosis (IPF).

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NXN-188 DB06096
small molecule

NXN-188 is a first-in-class, dual-action small molecule incorporating both neuronal nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of acute migraine.

Target Protein:
Nitric oxide synthase 15-hydroxytryptamine receptor 1B5-hydroxytryptamine receptor 1D
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biotech

NY-ESO-1 peptide vaccine is an investigational cancer immunotherapy. It contains a peptide derived from the cancer-testis antigen (NY-ESO-1).

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Nylidrin Approved DB06152
small molecule | CAS: 447-41-6

Nylidrin, also known as _buphenine_ belongs to the category of drugs called _vasodilators_, which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. Some studies show the evidence of improving cognitive impairment in selected i…

Kategori:
2-Amino-1-Phenylethanol DerivativesAdrenergic AgentsAdrenergic Agonists +29
Target Protein:
Interferon alpha/beta receptor 2Voltage-dependent T-type calcium channel subunit alpha-1I
Waktu ParuhDuration of action …
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Nystatin Approved DB00646
small molecule | CAS: 1400-61-9

Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species.[L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this …

Kategori:
Alimentary Tract and MetabolismAnti-Infective AgentsAntidiarrheals, Intestinal Antiinflammatory/antiinfective Agents +17
Target Protein:
Ergosterol
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Vol. DistribusiNystatin is not abs…
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NYX-2925 DB19149
small molecule | CAS: 2012536-16-0

NYX-2925 is under investigation in clinical trial NCT04146896 (Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)).

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small molecule

Deskripsi belum tersedia.

Target Protein:
4-hydroxy-tetrahydrodipicolinate synthase
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small molecule

Deskripsi belum tersedia.

Target Protein:
Transaldolase B
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NZ-1002 DB17688
biotech

Deskripsi belum tersedia.

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small molecule

Deskripsi belum tersedia.

Target Protein:
Poly [ADP-ribose] polymerase 1Exotoxin AElongation factor 2 +3
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin S
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small molecule

Deskripsi belum tersedia.

Target Protein:
Serine/threonine-protein kinase/endoribonuclease IRE1
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
ATP-dependent Clp protease proteolytic subunit
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-secretase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-secretase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-secretase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Vascular endothelial growth factor receptor 2
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small molecule

Deskripsi belum tersedia.

Target Protein:
Vascular endothelial growth factor receptor 2
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small molecule

Deskripsi belum tersedia.

Target Protein:
Carboxypeptidase A1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Carboxypeptidase A1
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Genetik -
small molecule | CAS: 67262-86-6

Deskripsi belum tersedia.

Kategori:
AntigensAntigens, NeoplasmBiological Factors +3
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small molecule | CAS: 5147-00-2

Deskripsi belum tersedia.

Target Protein:
Prostaglandin G/H synthase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Capsid scaffolding proteinSubtilisin SavinaseTrypsin-2 +2
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o-Cymen-5-ol DB15901
small molecule | CAS: 3228-02-2

Deskripsi belum tersedia.

Kategori:
Benzene Derivatives
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small molecule | CAS: 27415-09-4

Deskripsi belum tersedia.

Kategori:
Acids, Carbocyclic
Target Protein:
o-succinylbenzoate synthaseo-succinylbenzoate synthaseo-succinylbenzoate synthase
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small molecule

Deskripsi belum tersedia.

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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
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small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Gag-Pol polyprotein
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Genetik -
small molecule

Deskripsi belum tersedia.

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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cyanovirin-N
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Mannose-binding protein C
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Pyridoxal kinase
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small molecule

Deskripsi belum tersedia.

Target Protein:
Serine/threonine-protein kinase Chk1Glycogen synthase kinase-3 betaCyclin-dependent kinase 4 +2
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Oat Approved DB10546
biotech

Oat allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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OAV201 DB17842
biotech

OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter. It was first developed by Novartis and investigated…

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OAV401 DB18254
biotech

Deskripsi belum tersedia.

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Obatoclax DB12191
small molecule | CAS: 803712-67-6

Obatoclax has been used in trials studying the treatment of AML, Leukemia, Myelofibrosis, Hodgkin's Lymphoma, and Mantle-Cell Lymphoma, among others.

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-Ring
Target Protein:
Apoptosis regulator Bcl-2Induced myeloid leukemia cell differentiation protein Mcl-1Bcl-2-like protein 1
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OBE101 DB05080
small molecule

OBE101 is a new weight loss drug developed by Obecure Ltd. It is a new formulation that is based on the vertigo medication, Betahistine. Obecure is repurposing betahistine, which is an H1 receptor agonist and partial H3 receptor antagonist for the treatment o…

Target Protein:
Histamine H1 receptorHistamine H3 receptor
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Obecabtagene autoleucel Approved DB17362
biotech

Obecabtagene autoleucel is an investigational autologous CD19 CAR T cell therapy.

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Obeldesivir DB18821
small molecule | CAS: 2647441-36-7

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4
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Obeticholic acid Approved DB05990
small molecule | CAS: 459789-99-2

Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation.[A192786] Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to…

Kategori:
Alimentary Tract and MetabolismBile Acid PreparationsBile acids and derivatives +14
Target Protein:
Bile acid receptor
Waktu ParuhThe biological half…
Vol. DistribusiThe volume of distr…
KlirensClearance informati…
Genetik -
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