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12560

Total database: 17430
Struktur (SMILES)
9109 (72.5%)
Target
6912 (55.0%)
Genomik
109 (0.9%)
Referensi
12560 (100.0%)

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Hasil Pencarian (12560)

Halaman 218 / 252
Sodium apolate DB13477
small molecule | CAS: 25053-27-4

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAlkenes +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium arsenite DB18508
small molecule | CAS: 7784-46-5

Deskripsi belum tersedia.

Kategori:
AnionsArsenicalsElectrolytes +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium aurothiomalate Approved DB09276
small molecule | CAS: 12244-57-4

Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. It is most effective in act…

Kategori:
Acids, AcyclicAntiinflammatory and Antirheumatic ProductsAntirheumatic Agents +13
Waktu Paruh12.5 days
Vol. DistribusiThe apparent volume…
Klirens7.0 ml/ kg/day
Genetik -
Sodium bicarbonate Approved DB01390
small molecule | CAS: 144-55-8

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Kategori:
AntacidsAntacids and AdsorbentsBicarbonates +13
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1HA-type voltage-gated potassium channel KCND3Hydrogen ions
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium bisulfite Approved DB14015
small molecule | CAS: 7631-90-5

Sodium bisulfite has been used externally for parasitic skin diseases and as a gastrointestinal antiseptic.

Kategori:
AnionsAnti-Infective AgentsAnti-Infective Agents, Local +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium borate Approved DB14505
small molecule | CAS: 1330-43-4

Deskripsi belum tersedia.

Kategori:
AnionsAnti-Infective AgentsBoric Acids +5
Waktu ParuhAccording to human …
Vol. DistribusiVolume of distribut…
KlirensA case report of ac…
Genetik -
Sodium camphorsulfonate Approved DB15950
small molecule | CAS: 21791-94-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium cation DB14516
small molecule | CAS: 17341-25-2

Deskripsi belum tersedia.

Kategori:
Increased Large Intestinal MotilityInhibition Large Intestine Fluid/Electrolyte AbsorptionLaxatives +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium chloride Approved DB09153
small molecule | CAS: 7647-14-5

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid o…

Kategori:
Alimentary Tract and MetabolismBlood and Blood Forming OrgansBlood Substitutes and Perfusion Solutions +14
Waktu Paruh17 minutes
Vol. DistribusiThe volume of distr…
Klirens-
Genetik -
Sodium chlorite DB13210
small molecule | CAS: 7758-19-2

Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, …

Kategori:
AnionsChlorine CompoundsCicatrizants +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium chromate Cr-51 Approved DB09380
small molecule | CAS: 10039-53-9

Deskripsi belum tersedia.

Kategori:
Radioactive Diagnostic Agent
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium citrate Approved DB09154
small molecule | CAS: 68-04-2

Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the me…

Kategori:
Acids, AcyclicAntacids and AdsorbentsAnticoagulants +21
Target Protein:
Carbonic anhydrase 4
Waktu Paruh18-54 min [A19414]
Vol. Distribusi19-39L [A19414].
KlirensTotal clearance of …
Genetik -
small molecule

Sodium copper chlorophyllin (SCC) is a water-soluble and bright green mixture derived from natural chlorophyll that has potential antimutagenic and antioxidant properties[A227718]. This compound is used as a food colorant and supplement[A227718]. SCC of t…

Kategori:
Anti-Infective Agents, LocalAntimutagenic AgentsChlorophyll +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 2156-56-1

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicChloroacetates +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium feredetate Approved DB13381
small molecule | CAS: 15708-41-5

Deskripsi belum tersedia.

Kategori:
AcetatesAcids, AcyclicAmines +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 34089-81-1

Sodium ferric gluconate complex is an iron replacement product for treatment of iron deficiency anemia. The stable macromolecular complex is negatively charged at alkaline pH with an apparent molecular weight of 289,000 – 440,000 daltons on gel chromatography…

Kategori:
Iron PreparationsParenteral Iron Replacement
Target Protein:
Ferritin light chainHemoglobin subunit betaHemoglobin subunit alpha
Waktu ParuhThe terminal elimin…
Vol. DistribusiUsing single-dose p…
KlirensTotal clearance ran…
Genetik -
Sodium fluoride Approved DB09325
small molecule | CAS: 7681-49-4

Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18].[L4894] Sodium fluoride's benefits on dental health were first o…

Kategori:
Alimentary Tract and MetabolismAnionsCaries Prophylactic Agents +13
Target Protein:
Hydroxyapatite
Waktu ParuhThe terminal plasma…
Vol. DistribusiFluoride distribute…
KlirensSodium fluoride is …
Genetik -
Sodium fluorophosphate Approved DB09484
small molecule | CAS: 10163-15-2

Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.

Kategori:
AcidsAcids, NoncarboxylicAlimentary Tract and Metabolism +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium glycerophosphate Approved DB09561
small molecule | CAS: 1334-74-3

Sodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. The extent of this reaction …

Kategori:
AlcoholsBlood and Blood Forming OrgansBlood Substitutes and Perfusion Solutions +10
Waktu ParuhInorganic phosphate…
Vol. Distribusi-
Klirens-
Genetik -
Sodium hydroxide Approved DB11151
small molecule | CAS: 1310-73-2

Sodium hydroxide is also known as _lye_ or _soda_ , or _caustic soda_ [L1971]. At room temperature, sodium hydroxide is a white crystalline odorless solid that absorbs moisture from the air. It is a synthetically manufactured substance. When dissolved in w…

Kategori:
AlkaliesAnionsCaustics +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium iodide Approved DB11119
small molecule | CAS: 7681-82-5

Sodium iodide is a water-soluble ionic compound with a crystal lattice. Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine. Radiolabelled compound…

Kategori:
IodidesIodine CompoundsReplacement Preparations +2
Waktu Paruh-
Vol. DistribusiIodides are distrib…
Klirens-
Genetik -
small molecule | CAS: 151-21-3

Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. SLS lowers surface tension of aqueous solutions and is used as fat emulsi…

Kategori:
AlcoholsAlkanesulfonatesAlkanesulfonic Acids +9
Target Protein:
Albumin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium lauryl sulfoacetate Approved DB13157
small molecule | CAS: 1847-58-1

Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.

Kategori:
Alimentary Tract and MetabolismDrugs for ConstipationEnemas
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7681-57-4

Deskripsi belum tersedia.

Kategori:
AnionsAutonomic AgentsBronchoconstrictor Agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium molybdate Approved DB14496
small molecule | CAS: 7631-95-0

Deskripsi belum tersedia.

Kategori:
ElementsMetalsMetals, Heavy +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium nitrate DB15952
small molecule | CAS: 7631-99-4

Deskripsi belum tersedia.

Kategori:
AnionsCarcinogensElectrolytes +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium oxybate Approved DB09072
small molecule | CAS: 502-85-2

Sodium oxybate (Xyrem) is a central nervous system (CNS) depressant used to treat cataplexy or excessive daytime sleepiness associated with narcolepsy.[L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmit…

Kategori:
Acids, AcyclicAdjuvants, AnesthesiaAnesthetics +9
Target Protein:
GABA(B) ReceptorSolute carrier family 52, riboflavin transporter, member 2
Waktu ParuhGHB has an eliminat…
Vol. DistribusiThe apparent volume…
KlirensIn healthy GHB-naïv…
Genetik -
Sodium phosphate P 32 Approved DB09370
small molecule | CAS: 7635-46-3

Deskripsi belum tersedia.

Kategori:
Antineoplastic AgentsDiagnostic AgentsNarrow Therapeutic Index Drugs +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium phosphate, dibasic Approved DB14502
small molecule | CAS: 7558-79-4

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAnions +8
Target Protein:
Carbonic anhydrase 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 10140-65-5

Deskripsi belum tersedia.

Kategori:
LaxativesOsmotic Laxatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium phosphate, monobasic Approved DB09449
small molecule | CAS: 7558-80-7

Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.

Kategori:
AcidsAcids, NoncarboxylicAgents that reduce seizure threshold +19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
LaxativesOsmotic Laxatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium stibogluconate Approved DB05630
small molecule | CAS: 16037-91-5

Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufacture…

Kategori:
Acids, AcyclicAgents Against Leishmaniasis and TrypanosomiasisAnti-Infective Agents +10
Target Protein:
DNA topoisomerase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium sulfate Approved DB09472
small molecule | CAS: 7757-82-6

Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the …

Kategori:
Alimentary Tract and MetabolismAnionsDrugs for Constipation +11
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu ParuhSerum sulfate: 8.5 …
Vol. Distribusi-
Klirens-
Genetik -
Sodium sulfide Approved DB11159
small molecule | CAS: 1313-82-2

Sodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes including the production of rubber chemicals, sulfur dye…

Kategori:
AnionsElectrolytesHydrogen Sulfide +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sodium tartrate Approved DB13707
small molecule | CAS: 868-18-8

Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food…

Kategori:
Acids, AcyclicAlimentary Tract and MetabolismCarbohydrates +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7758-29-4

Sodium tripolyphosphate is an inorganic compound with formula Na5P3O10 and the sodium salt of the polyphosphate penta-anion. It is used as a component of a wide range domestic and industrial products, particularly detergents.

Kategori:
AcidsAcids, NoncarboxylicAnions +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sofalcone DB05197
small molecule | CAS: 64506-49-6

Sofalcone is a mucosal protective agent that has been reported to inhibit growth of Helicobacter pylori. on adherence, production of vacuolating toxin (VT), and induction of interleukin-8 (IL-8) secretion by H. pylori.

Kategori:
Anti-Ulcer AgentsBenzopyransChromones +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sofinicline DB12527
small molecule | CAS: 799279-80-4

Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies, Diabetic Polyneuropathy, and Diabetic Neuropathic Pain, among others.

Kategori:
Aza Compounds
Target Protein:
Neuronal acetylcholine receptor subunit alpha-4Neuronal acetylcholine receptor subunit beta-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 1418200-58-4

Sofituzumab vedotin is under investigation in clinical trial NCT01335958 (Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sofosbuvir Approved DB08934
small molecule | CAS: 1190307-88-0

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is c…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +18
Target Protein:
Genome polyproteinRNA-dependent RNA-polymerase
Waktu ParuhSofosbuvir has a te…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of so…
Genetik -
Sofpironium Approved DB19325
small molecule | CAS: 1628251-49-9

Sofpironium is a "soft" anticholinergic analog of [glycopyrronium] that has been modified with a readily hydrolyzable ester moiety.[L51109] Soft drugs are designed to reduce systemic toxicity while enhancing local efficacy by employing retrometabolic drug des…

Kategori:
Anticholinergic AgentsCytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (strength unknown) +13
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor
Waktu ParuhThe _in vitro_ half…
Vol. Distribusi-
Klirens-
Genetik -
Solabegron DB06190
small molecule | CAS: 252920-94-8

Solabegron (GW-427,353) is a selective ?3 adrenoceptor agonist being developed for the treatment of overactive bladder and irritable bowel syndrome.

Kategori:
Acids, CarbocyclicAdrenergic AgentsAdrenergic Agonists +8
Target Protein:
Beta-3 adrenergic receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solamargine DB12700
small molecule | CAS: 20311-51-7

Solamargine has been used in trials studying the treatment of Actinic Keratosis.

Kategori:
Alkaloids
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solanezumab DB11756
biotech | CAS: 955085-14-0

Solanezumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers Disease, Familial.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solasodine DB18813
small molecule | CAS: 126-17-0

Deskripsi belum tersedia.

Kategori:
Alkaloids
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solasonine DB17103
small molecule | CAS: 19121-58-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsStereoisomerism
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solcoseryl DB15794
biotech

Deskripsi belum tersedia.

Kategori:
Complex MixturesTissue Extracts
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Solifenacin Approved DB01591
small molecule | CAS: 242478-37-1

Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.[L7511] It has a long duration of action as it is usually taken once daily.[L7511] Solifenacin was grante…

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAnticholinergic Agents +19
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M4 +2
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of so…
Genetik -
Solnatide DB12136
biotech | CAS: 259206-53-6

Solnatide has been used in trials studying the treatment of Acute Lung Injury.

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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