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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

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Hasil Pencarian (13591)

Halaman 217 / 272
Protein S human Approved DB13149
biotech

Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties [A19561]. It serves as a negative feedback mechanism in the coagulation cascade.

Kategori:
Amino Acids, Peptides, and ProteinsAnticoagulantsBiological Factors +8
Target Protein:
Coagulation factor VCoagulation factor XVitamin K-dependent protein C
Waktu Paruh-
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Prothipendyl DB12958
small molecule | CAS: 303-69-5

Prothipendyl has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.

Kategori:
Antipsychotic AgentsCentral Nervous System DepressantsNervous System +3
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Prothrombin Approved DB11311
biotech | CAS: 9001-26-7

Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +7
Target Protein:
Fibrinogen alpha chainFibrinogen beta chainCoagulation factor XIII A chain +1
Waktu ParuhApproximately 60h […
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Protiofate DB13632
small molecule | CAS: 58416-00-5

Deskripsi belum tersedia.

Kategori:
Genito Urinary System and Sex HormonesGynecological Antiinfectives and Antiseptics
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Protirelin Approved DB09421
small molecule | CAS: 24305-27-9

Protirelin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH). It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) a…

Kategori:
Amino Acids, Peptides, and ProteinsDiagnostic AgentsHormones +12
Target Protein:
Thyrotropin-releasing hormone receptor
Waktu Paruh-
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small molecule | CAS: 139-85-5

Also known as protocatechuic aldehyde, protocatechualdehyde is a naturally-occuring phenolic aldehyde that is found in barley, green cavendish bananas, grapevine leaves and root of the herb S. miltiorrhiza [A27224]. Protocatechualdehyde possesses antiprolifer…

Kategori:
AldehydesAnticoagulantsBenzene Derivatives +2
Target Protein:
Amine oxidase [flavin-containing] B
Waktu Paruh-
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Protokylol Approved DB06814
small molecule | CAS: 136-70-9

Protokylol is a ?-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.

Kategori:
Adrenergic AgonistsAdrenergic beta-2 Receptor AgonistsAdrenergic beta-Agonists +15
Target Protein:
Beta-2 adrenergic receptorBeta-1 adrenergic receptor
Waktu Paruh-
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Protoporphyrin DB02285
small molecule | CAS: 553-12-8

Deskripsi belum tersedia.

Kategori:
Biological FactorsDermatologicalsHeterocyclic Compounds, Fused-Ring +4
Target Protein:
Hematopoietic prostaglandin D synthaseFerritin light chain
Waktu Paruh-
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Protriptyline Approved DB00344
small molecule | CAS: 438-60-8

Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individ…

Kategori:
Adrenergic AgentsAdrenergic Uptake InhibitorsAgents that produce hypertension +24
Target Protein:
Sodium-dependent noradrenaline transporterSodium-dependent serotonin transporter
Waktu Paruh-
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Proxalutamide DB16065
small molecule | CAS: 1398046-21-3

Proxalutamide is under investigation in clinical trial NCT03899467 (The Safety and Tolerability of Proxalutamide (GT0918) in Subjects With Metastatic Castrate Resistant Prostate Cancer).

Kategori:
HydantoinsImidazolesImidazolidines
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Proxazole DB13819
small molecule | CAS: 5696-09-3

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismDrugs for Functional Gastrointestinal DisordersOxazoles
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Proxibarbal Approved DB13253
small molecule | CAS: 2537-29-3

Proxibarbal is a derivative of barbiturates, which has been used to treat migraines. Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing immunoallergic thrombocytopenia [L5476].

Kategori:
Barbiturates, PlainCentral Nervous System AgentsCentral Nervous System Depressants +5
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Proxyphylline DB13449
small molecule | CAS: 603-00-9

Deskripsi belum tersedia.

Kategori:
AlkaloidsAnti-Asthmatic AgentsAutonomic Agents +11
Waktu Paruh-
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Prucalopride Approved DB06480
small molecule | CAS: 179474-81-8

Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties.[A37348] The high selectivity of prucalopride allowed further development as it pr…

Kategori:
Alimentary Tract and MetabolismAntidepressive AgentsCentral Nervous System Depressants +17
Target Protein:
5-hydroxytryptamine receptor 4
Waktu ParuhThe reported half-l…
Vol. DistribusiThe mean volume of …
KlirensPrucalopride renal …
Genetik -
Prulifloxacin DB11892
small molecule | CAS: 123447-62-1

Prulifloxacin has been investigated for the treatment of Urinary Tract Infection.

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +15
Target Protein:
DNA topoisomerase 4 subunit ADNA gyrase subunit ADNA gyrase subunit B
Waktu Paruh-
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Genetik -
biotech

Prunus armeniaca seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
AngiospermsBiological ProductsComplex Mixtures +11
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Prussian blue Approved DB06783
small molecule | CAS: 14038-43-8

Prussian blue is described as a deep blue pigment that is produced when the oxidation of ferrous ferrocyanide salts occurs. It contains ferric hexacyanoferrate(II) in a cubic lattice crystal structure. It is insoluble in water but also tends to form a colloid…

Kategori:
AnionsAntidotesChelating Activity +11
Waktu Paruh-
Vol. DistribusiHistopathological e…
KlirensThe clearance from …
Genetik -
Pruvanserin DB13094
small molecule | CAS: 443144-26-1

Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders.

Target Protein:
5-hydroxytryptamine receptor 2A
Waktu Paruh-
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PRX-03140 DB05596
small molecule | CAS: 869493-21-0

Deskripsi belum tersedia.

Waktu Paruh-
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PRX-07034 DB05993
small molecule | CAS: 903580-39-2

Deskripsi belum tersedia.

Target Protein:
5-hydroxytryptamine receptor 6
Waktu Paruh-
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PRX-08066 DB05607
small molecule

Deskripsi belum tersedia.

Kategori:
Antidepressive AgentsCentral Nervous System DepressantsSerotonin 5-HT2 Receptor Antagonists +3
Target Protein:
5-hydroxytryptamine receptor 2B
Waktu Paruh-
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PS386113 DB05211
small molecule

PS386113 is a small molecule drug candidate under investigation for the treatment of inflammatory disorders. It is being developed by Schering-Plough and Pharmacopeia. Little information has been released about PS386113.

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Pseudoephedrine Approved DB00852
small molecule | CAS: 90-82-4

Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first res…

Kategori:
Adrenergic AgonistsAdrenergic alpha-1 Receptor AgonistsAdrenergic alpha-2 Receptor Agonists +30
Target Protein:
Sodium-dependent noradrenaline transporterD(2) dopamine receptorSodium-dependent dopamine transporter +10
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe apparent volume…
KlirensA 60mg oral dose of…
Genetik -
small molecule | CAS: 567-19-1

Deskripsi belum tersedia.

Waktu Paruh-
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Pseudotropine DB04026
small molecule | CAS: 135-97-7

Deskripsi belum tersedia.

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

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PSI-352938 DB12896
small molecule | CAS: 1199809-32-9

PSI-352938 has been used in trials studying the treatment of Hepatitis C and Hepatitis C, Chronic.

Kategori:
CarbohydratesGlycosidesNucleic Acids, Nucleotides, and Nucleosides
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Psicose DB15087
small molecule | CAS: 23140-52-5

Psicose is under investigation in clinical trial NCT02459834 (The Fructose and Allulose Catalytic Effects (FACE) Trial).

Kategori:
CarbohydratesHexosesKetoses +1
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PSN357 DB05044
small molecule

PSN357 is a glycogen phosphorylase inhibitor (GPI), which is designed to rapidly lower blood glucose levels by preventing glycogen breakdown to glucose in the liver.

Target Protein:
Glycogen phosphorylase, liver form
Waktu Paruh-
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PSN9301 DB05001
small molecule

PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes. PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indica…

Target Protein:
Dipeptidyl peptidase 4
Waktu Paruh-
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PT-2385 DB16055
small molecule | CAS: 1672665-49-4

PT-2385 is under investigation in clinical trial NCT03108066 (PT2385 for the Treatment of Von Hippel-lindau Disease-associated Clear Cell Renal Cell Carcinoma).

Target Protein:
Endothelial PAS domain-containing protein 1Hypoxia-inducible factor 1-alpha
Waktu Paruh-
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Genetik -
PT217 DB18472
biotech

PT217 is a bispecific Antibody against DLL3 and CD47

Waktu Paruh-
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PTC299 DB05173
small molecule

PTC299 is a novel, orally administered small-molecule designed to inhibit the production of vascular endothelial growth factor (VEGF) in tumors. Overexpression of VEGF plays a key role in multiple diseases including cancer and macular degeneration. PTC299 was…

Kategori:
Acids, AcyclicHeterocyclic Compounds, Fused-RingIndoles
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Pteric acid DB04357
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Aldehyde oxidoreductase
Waktu Paruh-
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small molecule

Deskripsi belum tersedia.

Target Protein:
Dihydropteroate synthaseDihydropteroate synthaseDihydropteroate synthase
Waktu Paruh-
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Pterostilbene DB17939
small molecule | CAS: 18259-15-9

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesBenzylidene Compounds
Waktu Paruh-
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PTI-110 DB18298
small molecule | CAS: 633700-15-9

Deskripsi belum tersedia.

Target Protein:
Amyloid-beta precursor protein
Waktu Paruh-
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PTI-801 DB05300
small molecule | CAS: 615580-67-1

PTI-801 represents a new class of drugs to treat pain. PTI-801 can minimize the opioid tolerance, dependence or addiction that is often associated with repeat use of oxycodone. It is a combination of oxycodone with ultralow-dose naltrexone, an opioid antagoni…

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PTX-100 DB18125
small molecule | CAS: 501010-06-6

Deskripsi belum tersedia.

Target Protein:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit beta
Waktu Paruh-
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Genetik -
biotech

Puccinia striiformis var. striiformis is a fungus which can provoke allergic reactions. Puccinia striiformis var. striiformis extract is used in allergenic testing.

Kategori:
Non-Standardized Fungal Allergenic Extract
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Pucotenlimab Approved DB17552
biotech | CAS: 2403647-03-8

Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours.[A257296] It is being investigated in other cancers.

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Pudexacianinium DB19161
small molecule | CAS: 2243793-21-5

Pudexacianinium is under investigation in clinical trial NCT05754333 (A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery).

Waktu Paruh-
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Puerarin DB12290
small molecule | CAS: 3681-99-0

Puerarin has been investigated for the treatment of Alcohol Abuse.

Kategori:
BenzopyransCardiovascular AgentsChromones +4
Target Protein:
5-hydroxytryptamine receptor 2C
Waktu Paruh-
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Pulocimab DB18938
biotech | CAS: 2428381-49-9

Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma).

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Pumactant DB04955
small molecule | CAS: 258856-56-3

Pumactant is a synthetic surfactant used for treating respiratory distress syndrome in neonates. It is a unique formulation of the naturally occurring phospholipids Dipalmitoylphosphatidycholine (DPPC) and Phosphatidyl Glycerol (PG).

Kategori:
LipidsMembrane LipidsPulmonary Surfactants
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Pumice DB14374
biotech | CAS: 1332-09-8

Pumice is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
MineralsSilicon Compounds
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Pumosetrag DB12402
small molecule | CAS: 153062-94-3

Pumosetrag has been used in trials studying Gastroesophageal Reflux Disease.

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small molecule

Deskripsi belum tersedia.

Target Protein:
Ribonuclease pancreatic
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Puromycin DB08437
small molecule | CAS: 53-79-2

Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate doses.

Kategori:
Acids, CarbocyclicAgents that produce neuromuscular block (indirect)Aminoglycoside Antibacterials +20
Target Protein:
Ribosomal protein uL16-likeLarge ribosomal subunit protein uL13Large ribosomal subunit protein uL14 +10
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