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12560

Total database: 17430
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9109 (72.5%)
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6912 (55.0%)
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109 (0.9%)
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12560 (100.0%)

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Halaman 212 / 252
Sagopilone DB12391
small molecule | CAS: 305841-29-6

Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to comb…

Kategori:
Anti-Bacterial AgentsAntineoplastic AgentsCytochrome P-450 CYP3A Inhibitors +8
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Sakuranetin DB08517
small molecule | CAS: 2957-21-3

Deskripsi belum tersedia.

Kategori:
BenzopyransBiological FactorsChromones +3
Target Protein:
Adenosine receptor A2bAdenosine receptor A1Adenosine receptor A3 +1
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small molecule | CAS: 183990-46-7

Deskripsi belum tersedia.

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Salicin DB19357
small molecule | CAS: 138-52-3

Deskripsi belum tersedia.

Kategori:
AlcoholsAnalgesicsAnalgesics, Non-Narcotic +11
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Salicylamide Approved DB08797
small molecule | CAS: 65-45-2

Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with bo…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +16
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small molecule | CAS: 25395-22-6

Deskripsi belum tersedia.

Kategori:
Amides
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Salinomycin DB11544
small molecule | CAS: 53003-10-4

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiparasitic Agents +8
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Salirasib DB12681
small molecule | CAS: 162520-00-5

Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.

Kategori:
Acids, CarbocyclicAlcoholsAntineoplastic Agents +11
Target Protein:
Serine/threonine-protein kinase mTORGTPase NRas
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biotech

Salix alba bark volatile oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Salix discolor pollen Approved DB10753
biotech

Salix discolor pollen is the pollen of the Salix discolor plant. Salix discolor pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Salix lasiolepis pollen Approved DB10752
biotech

Salix lasiolepis pollen is the pollen of the Salix lasiolepis plant. Salix lasiolepis pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Salmeterol Approved DB00938
small molecule | CAS: 89365-50-4

Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-2 Receptor Agonists +35
Target Protein:
Beta-2 adrenergic receptorBeta-1 adrenergic receptorBeta-3 adrenergic receptor
Waktu ParuhThe half life of sa…
Vol. DistribusiIn asthmatic patien…
KlirensThe average clearan…
Genetik -
Salmon calcitonin Approved DB00017
biotech | CAS: 47931-85-1

Synthetic peptide, 32 residues long formulated as a nasal spray.

Kategori:
Amino Acids, Peptides, and ProteinsBone Density Conservation AgentsBone Density, drug effects +15
Target Protein:
Calcitonin receptor
Waktu ParuhHalf-life eliminati…
Vol. Distribusi0.15 to 0.3 L/kg
Klirens-
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Salsalate Approved DB01399
small molecule | CAS: 552-94-3

Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the …

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +17
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
Waktu ParuhThe parent compound…
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small molecule | CAS: 96574-01-5

Salvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).

Kategori:
Acids, CarbocyclicAntineoplastic AgentsCinnamates +4
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small molecule | CAS: 121521-90-2

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAldehyde ReductaseAldehyde Reductase, antagonists & inhibitors +6
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Salvinorin A DB12327
small molecule | CAS: 83729-01-5

Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations.

Kategori:
AlkaloidsCentral Nervous System AgentsCentral Nervous System Depressants +6
Target Protein:
Mu-type opioid receptorDelta-type opioid receptorKappa-type opioid receptor
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Samalizumab DB12636
biotech | CAS: 1073059-33-2

Samalizumab has been used in trials studying the treatment of Multiple Myeloma and B-cell Chronic Lymphocytic Leukemia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
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Samarium (153Sm) lexidronam Approved DB05273
small molecule | CAS: 122575-21-7

Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the functio…

Kategori:
AnalgesicsAnalgesics, Non-NarcoticCentral Nervous System Agents +7
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Samarium Sm-153 DB12905
small molecule | CAS: 15766-00-4

Samarium 153 has been used in trials studying the supportive care of Pain, Lung Cancer, Breast Cancer, Prostate Cancer, and Metastatic Cancer.

Kategori:
ElementsIsotopesLanthanoid Series Elements +2
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Samatasvir DB12660
small molecule | CAS: 1312547-19-5

Samatasvir has been used in trials studying the treatment of Hepatitis C, Chronic, Chronic Hepatitis C Virus, and Chronic Hepatitis C Infection.

Kategori:
Acids, AcyclicHeterocyclic Compounds, Fused-Ring
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Samidorphan Approved DB12543
small molecule | CAS: 852626-89-2

[Olanzapine] is an effective atypical antipsychotic that, like other antipsychotics, is associated with weight gain, metabolic dysfunction, and increased risk of type II diabetes.[A235638, A235643] Samidorphan is a novel opioid antagonist structurally related…

Kategori:
AlkaloidsAntipsychotic AgentsCentral Nervous System Agents +17
Target Protein:
Mu-type opioid receptorKappa-type opioid receptorDelta-type opioid receptor
Waktu ParuhSamidorphan has a m…
Vol. DistribusiSamidorphan followi…
KlirensSamidorphan has a m…
Genetik -
Samuraciclib DB16061
small molecule | CAS: 1805833-75-3

Samuraciclib is under investigation in clinical trial NCT03363893 (Modular Study to Evaluate CT7001 Alone in Cancer Patients With Advanced Malignancies).

Target Protein:
Cyclin-dependent kinase 7
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small molecule | CAS: 141646-08-4

Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability of Sanfetrinem Cilexetil).

Kategori:
Amides
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Sapablursen DB18608
biotech | CAS: 2273007-95-5

Sapablursen is a synthetic 2'-O-(2-methoxyethyl)-modified antisense oligonucleotide linked to a tri-antennary cluster of N-acetyl galactosamine (GalNAc3) sugars targeting transmembrane protease, serine 6 messenger ribonucleic acid

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Sapacitabine DB06365
small molecule | CAS: 151823-14-2

Deskripsi belum tersedia.

Kategori:
Antineoplastic AgentsNucleic Acids, Nucleotides, and NucleosidesNucleosides +2
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Sapanisertib DB11836
small molecule | CAS: 1224844-38-5

Sapanisertib has been used in trials studying the treatment of HCC, Solid Tumor, Gliosarcoma, Liver Cancer, and Glioblastoma, among others.

Kategori:
Heterocyclic Compounds, Fused-RingPurines
Target Protein:
Serine/threonine-protein kinase mTOR
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Saposin C DB17380
biotech

Saposin C is a lysosomal protein. Recombinant, non-glycosylated Saposin C is an active ingredient of BXQ-350, which is a novel, investigational anti-neoplastic therapy. BXQ-350 consists of Saposin C and the phospholipid dioleoylphosphatidyl-serine (DOPS), a p…

Kategori:
CoenzymesEnzymes and CoenzymesSphingolipid Activator Proteins
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Sapropterin Approved DB00360
small molecule | CAS: 62989-33-7

Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine…

Kategori:
Alimentary Tract and MetabolismAminesBCRP/ABCG2 Inhibitors +15
Target Protein:
Phenylalanine-4-hydroxylaseNitric oxide synthase 3Tyrosine 3-monooxygenase +1
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Saquinavir Approved DB01232
small molecule | CAS: 127779-20-8

Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection. In 1995 it became the first protease inhibitor approved by the FDA, followed shortl…

Kategori:
Agents Causing Muscle ToxicityAnti-HIV AgentsAnti-Infective Agents +44
Target Protein:
Gag-Pol polyproteinPol polyprotein
Waktu Paruh-
Vol. DistribusiThe steady-state vo…
KlirensThe systemic cleara…
Genetik -
SAR-125844 DB15382
small molecule | CAS: 1116743-46-4

SAR-125844 is under investigation in clinical trial NCT01391533 (Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors).

Kategori:
AmidesHeterocyclic Compounds, Fused-RingSulfur Compounds +1
Target Protein:
Hepatocyte growth factor receptor
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SAR-405838 DB12541
small molecule | CAS: 1303607-60-4

SAR405838 has been used in trials studying the treatment of Neoplasm Malignant.

Kategori:
Heterocyclic Compounds, Fused-RingP-glycoprotein substrates
Target Protein:
Cellular tumor antigen p53
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SAR-439459 DB17864
biotech | CAS: 2114339-57-8

SAR-439459 is a pan-transforming Growth Factor-beta (TGF?) neutralizing antibody.[A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis Imperfecta.

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SAR422459 DB17908
biotech

SAR422459 is a Lentiviral Vector Containing The Human Abca4 Gene that is currently being investigated to treat Stargardt disease.

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SAR443122 DB16492
small molecule | CAS: 2125450-76-0

SAR443122, was investigated in several clinical trials to evaluate its safety and efficacy. NCT04469621 was studied in severe COVID-19 patients, while NCT05588843 is currently recruiting participants with ulcerative colitis. Additionally, NCT04781816, which w…

Kategori:
Experimental Unapproved Treatments for COVID-19
Target Protein:
Receptor-interacting serine/threonine-protein kinase 1
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SAR445136 DB17708
biotech

SAR445136 is an investigational zinc finger nuclease gene-edited cell therapy. It consists of autologous CD34+ hematopoietic stem precursor cells (HSPC) modified ex vivo by zinc finger nucleases (ZFN) that target the BCL11A gene erythroid-specific enhancer (E…

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small molecule | CAS: 110880-55-2

Sar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist. It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species.

Kategori:
Amino Acids, Peptides, and ProteinsAutacoidsBiological Factors +11
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Saracatinib DB11805
small molecule | CAS: 379231-04-6

Saracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer.

Kategori:
Antineoplastic AgentsCytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A4 Inhibitors +6
Target Protein:
Proto-oncogene tyrosine-protein kinase SrcTyrosine-protein kinase ABL1
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Sarafloxacin DB11491
small molecule | CAS: 98105-99-8

Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.

Kategori:
4-QuinolonesAnti-Bacterial AgentsCytochrome P-450 CYP1A2 Inhibitors +8
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Sarconeos DB16457
small molecule

Sarconeos is an activator of the MAS receptor.

Kategori:
Experimental Unapproved Treatments for COVID-19
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Sarcosine DB12519
small molecule | CAS: 107-97-1

Sarcosine has been investigated for the treatment of Schizophrenia.

Kategori:
Amino AcidsAmino Acids, Peptides, and ProteinsN-substituted Glycines
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Sarecycline Approved DB12035
small molecule | CAS: 1035654-66-0

Sarecycline is a semi-synthetic derivative of tetracycline that was initially discovered by Paratek Pharmaceuticals from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 [A40005]. After completing various phase-II and phase-III …

Kategori:
Anti-Acne PreparationsAnti-Acne Preparations for Systemic UseAnti-Bacterial Agents +7
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe mean apparent v…
KlirensThe mean apparent o…
Genetik -
Sarilumab Approved DB11767
biotech | CAS: 1189541-98-7

Sarilumab is a fully human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling cascades of IL-6.[A27262] Sarilumab was develope…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +22
Target Protein:
Interleukin-6 receptor subunit alphaHigh affinity immunoglobulin gamma Fc receptor ILow affinity immunoglobulin gamma Fc region receptor II-a +3
Waktu ParuhThe half-life will …
Vol. DistribusiIn patients with rh…
KlirensSarilumab is not el…
Genetik -
Sarizotan DB06454
small molecule | CAS: 351862-32-3

Deskripsi belum tersedia.

Target Protein:
5-hydroxytryptamine receptor 1AD(2) dopamine receptorD(3) dopamine receptor
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Saroglitazar DB13115
small molecule | CAS: 495399-09-2

Saroglitazar has been investigated for the treatment of Fatty Liver.

Kategori:
Acids, Carbocyclic
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Sarpogrelate DB12163
small molecule | CAS: 125926-17-2

Sarpogrelate has been investigated for the treatment of Diabetes Mellitus, Diabetic Nephropathy, Coronary Artery Disease, and Renal Insufficiency, Chronic.

Kategori:
Acids, AcyclicAntidepressive AgentsAntiplatelet agents +8
Target Protein:
5-hydroxytryptamine receptor 2C5-hydroxytryptamine receptor 2A
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Sarracenia Purpurea Approved DB13965
biotech

_Sarracenia purpurea_, commonly known as the purple pitcher plant, northern pitcher plant, turtle socks, or side-saddle flower, is a perennial carnivorous plant in the family _Sarraceniaceae_. _Sarracenia purpurea_ attract and trap insects within their pitche…

Kategori:
Miscellaneous Analgesics and Antipyretics
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
biotech

SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated mRNA encoding the receptor binding domain of SARS-CoV-2[A220048]. It is the first COVID-19 mRNA vaccine to be approved for clinical trials …

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biotech

The University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations (CEPI) and CSL has developed a COVID-19 candidate, SARS-CoV-2 Sclamp. The vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine plat…

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biotech

Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer.[L48902] It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SAR…

Kategori:
COVID-19 VaccinesVaccinesViral Vaccines
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Menampilkan 10551–10600 dari 12560
Sebelumnya Halaman 212 / 252 Berikutnya