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11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

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Hasil Pencarian (11778)

Halaman 208 / 236
Sucrose Approved DB02772
small molecule | CAS: 57-50-1

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +12
Target Protein:
Beta-lactamaseTaste receptor type 1 member 2Beta-lactamase +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sucrosofate DB01901
small molecule | CAS: 57680-56-5

Deskripsi belum tersedia.

Kategori:
Anti-Ulcer AgentsCarbohydratesDisaccharides +3
Target Protein:
Fibroblast growth factor 1Fibroblast growth factor receptor 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sudapyridine DB18984
small molecule | CAS: 1859978-72-5

Sudapyridine is under investigation in clinical trial NCT05824871 (Sudapyridine (WX-081) in Rr/mdr/xdr-tuberculosis Patients).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sufentanil Approved DB00708
small molecule | CAS: 56030-54-7

Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as _Dsuvia_, the sublingual form is u…

Kategori:
Adjuvants, AnesthesiaAgents that produce hypertensionAnalgesics +25
Target Protein:
Mu-type opioid receptorDelta-type opioid receptorKappa-type opioid receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiSufentanil has a di…
KlirensThe total plasma cl…
Genetik -
Sugammadex Approved DB06206
small molecule | CAS: 343306-71-8

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause …

Kategori:
AntidotesCarbohydratesCompounds used in a research, industrial, or household setting +6
Waktu ParuhAbout 2 hours
Vol. DistribusiAt steady state, th…
Klirens88L/min
Genetik -
Sugemalimab DB16641
biotech | CAS: 2256084-03-2

Sugemalimab is a fully human, full-length IgG4 monoclonal anti-PD-L1 antibody discovered by CStone Pharmaceuticals and being investigated against relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) in adult patients and T-cell ly…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulanemadlin DB17285
biotech | CAS: 1451199-98-6

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbactam Approved DB09324
small molecule | CAS: 68373-14-8

Sulbactam is a beta (?)-lactamase inhibitor and a derivative of the basic penicillin nucleus.[L50131] When given in combination with ?-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydro…

Kategori:
AmidesAnti-Infective AgentsAntibacterials for Systemic Use +10
Target Protein:
Beta-lactamase
Waktu ParuhIn healthy voluntee…
Vol. DistribusiThe steady-state vo…
KlirensEenal clearance is …
Genetik -
small molecule | CAS: 69388-79-0

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial Agentsbeta-Lactams +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbenicillin DB13693
small molecule | CAS: 41744-40-5

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulbentine DB13671
small molecule | CAS: 350-12-9

Deskripsi belum tersedia.

Kategori:
Antifungals for Dermatological UseAntifungals for Topical UseDermatologicals
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulconazole Approved DB06820
small molecule | CAS: 61318-90-9

Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntifungals for Dermatological Use +11
Target Protein:
Lanosterol 14-alpha demethylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulesomab Approved DB13976
biotech | CAS: 167747-19-5

Market product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfabenzamide Approved DB09355
small molecule | CAS: 127-71-9

Sulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.

Kategori:
AmidesSulfonesSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 116-45-0

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfacytine Approved DB01298
small molecule | CAS: 17784-12-2

Sulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamide…

Kategori:
AmidesAminesAniline Compounds +5
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfadoxine Approved DB01299
small molecule | CAS: 2447-57-6

A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.

Kategori:
AmidesAminesAniline Compounds +15
Target Protein:
Dihydropteroate synthetaseAmine oxidase [flavin-containing] BDihydropteroate synthase +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfaguanidine DB13726
small molecule | CAS: 57-67-0

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAmidesAmidines +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 515-64-0

Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has been officially approved for use anywhere [A175672].

Kategori:
AmidesAminesAniline Compounds +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamazone DB13556
small molecule | CAS: 65761-24-2

Deskripsi belum tersedia.

Kategori:
Antibacterials for Systemic UseAntiinfectives for Systemic UseLong-Acting Antibacterial Sulfonamides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamerazine Approved DB01581
small molecule | CAS: 127-79-7

A sulfanilamide that is used as an antibacterial agent.

Kategori:
AmidesAminesAniline Compounds +16
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamethazine Approved DB01582
small molecule | CAS: 57-68-1

A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.

Kategori:
AmidesAminesAniline Compounds +13
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamethizole Approved DB00576
small molecule | CAS: 144-82-1

A sulfathiazole antibacterial agent.

Kategori:
AmidesAminesAniline Compounds +26
Target Protein:
Dihydropteroate synthase
Waktu Paruh3-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Sulfamethoxazole Approved DB01015
small molecule | CAS: 723-46-6

Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria.[L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis…

Kategori:
Agents causing hyperkalemiaAgents Causing Muscle ToxicityAmines +39
Target Protein:
Dihydropteroate synthase
Waktu ParuhThe average serum h…
Vol. DistribusiThe volume of distr…
KlirensThe oral and renal …
Genetik -
small molecule | CAS: 80-35-3

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfametomidine DB13485
small molecule | CAS: 3772-76-7

Deskripsi belum tersedia.

Kategori:
Antibacterials for Systemic UseAntiinfectives for Systemic UseLong-Acting Antibacterial Sulfonamides +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfametopyrazine Approved DB00664
small molecule | CAS: 152-47-6

Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.

Kategori:
AmidesAminesAniline Compounds +17
Target Protein:
Dihydropteroate synthetaseDihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfametrole DB15975
small molecule | CAS: 32909-92-5

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfamoxole DB08798
small molecule | CAS: 729-99-7

Sulfamoxole is an antibacterial in the sulfonamide class.

Kategori:
AmidesAminesAniline Compounds +14
Target Protein:
Dihydropteroate synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfanilamide Approved DB00259
small molecule | CAS: 63-74-1

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.

Kategori:
AmidesAminesAniline Compounds +21
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfanitran DB11463
small molecule | CAS: 122-16-7

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfaphenazole Approved DB06729
small molecule | CAS: 526-08-9

Sulfaphenazole is a sulfonamide antibacterial.

Kategori:
AmidesAminesAniline Compounds +27
Target Protein:
Dihydropteroate synthaseCytochrome P450 2C9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfasalazine Approved DB00795
small molecule | CAS: 599-79-1

Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metab…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAlimentary Tract and Metabolism +23
Target Protein:
Broad substrate specificity ATP-binding cassette transporter ABCG2Transcription factor RelBTranscription factor p65 +12
Waktu ParuhThe observed plasma…
Vol. DistribusiFollowing intraveno…
KlirensThe calculated clea…
Genetik -
Sulfate ion DB14546
small molecule | CAS: 14808-79-8

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesIncreased Large Intestinal Motility +9
Target Protein:
Carbonic anhydrase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfathiazole Approved DB06147
small molecule | CAS: 72-14-0

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those…

Kategori:
AmidesAminesAniline Compounds +16
Target Protein:
Dihydropteroate synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfatide DB04780
small molecule

Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.

Kategori:
Acidic GlycosphingolipidsCarbohydratesGlycoconjugates +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfatolamide DB13547
small molecule | CAS: 1161-88-2

Deskripsi belum tersedia.

Kategori:
AmidesAminesAniline Compounds +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfinpyrazone Approved DB01138
small molecule | CAS: 57-96-5

A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

Kategori:
Antigout PreparationsAntiplatelet agentsBSEP/ABCB11 Substrates +19
Target Protein:
Solute carrier family 22 member 12Multidrug resistance-associated protein 1ATP-binding cassette sub-family C member 2 +1
Waktu ParuhApproximately 4-6 h…
Vol. Distribusi-
Klirens-
Genetik -
Sulfisoxazole Approved DB00263
small molecule | CAS: 127-69-5

A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.

Kategori:
AmidesAminesAniline Compounds +26
Target Protein:
Dihydropteroate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 297-83-6

Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans [A174970].

Kategori:
Benzene DerivativesColoring AgentsCompounds used in a research, industrial, or household setting +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 182410-00-0

Deskripsi belum tersedia.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingCyclodextrins +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfogaiacol DB15992
small molecule | CAS: 7134-11-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfotep DB11497
small molecule | CAS: 3689-24-5

Deskripsi belum tersedia.

Kategori:
Organophosphorus CompoundsSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfoxone Approved DB01145
small molecule | CAS: 144-76-3

Sulfoxone is a water-soluble sulfone used as an antileprosy drug. It has been used with limited success in the treatment of dermatitis herpetiformis.

Kategori:
Antiinfectives for Systemic UseAntimycobacterialsDrugs for Treatment of Lepra +2
Target Protein:
Dihydropteroate synthetase
Waktu Paruh3-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Sulfur chloride DB14647
small molecule | CAS: 10025-67-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfur dioxide DB16426
small molecule | CAS: 7446-09-5

Deskripsi belum tersedia.

Kategori:
Air PollutantsEnvironmental PollutantsGases +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulfuric acid DB11309
small molecule | CAS: 7664-93-9

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicSulfur Acids +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulisobenzone DB11185
small molecule | CAS: 4065-45-6

Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations [F38]. It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage [L2153]. The UV-filter s…

Kategori:
Benzene DerivativesDrugs that are Mainly Renally ExcretedKetones +1
Target Protein:
Skin epithelial cells
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Suloctidil DB13340
small molecule | CAS: 54767-75-8

Deskripsi belum tersedia.

Kategori:
AlcoholsAminesAmino Alcohols +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Sulodexide Approved DB06271
biotech | CAS: 57821-29-1

Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).

Kategori:
Agents causing hyperkalemiaAnticoagulantsBlood and Blood Forming Organs +8
Target Protein:
Heparin cofactor 2Antithrombin-III
Waktu ParuhThe elimination hal…
Vol. DistribusiCmax=516+/-77.54ng/…
Klirens2.70+/-0.58L/h
Genetik -
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