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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (14063)

Halaman 207 / 282
small molecule

Deskripsi belum tersedia.

Target Protein:
Cyclomaltodextrin glucanotransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxitriptan Approved DB02959
small molecule | CAS: 4350-09-8

5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in the United Kingdom, United States and Canada as a dietar…

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +8
Target Protein:
Tryptophan--tRNA ligase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxitropium DB12086
small molecule | CAS: 99571-64-9

Oxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive.

Kategori:
Agents producing tachycardiaAlkaloidsAnticholinergic Agents +9
Target Protein:
Muscarinic acetylcholine receptor M5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxogluric acid DB08845
small molecule | CAS: 328-50-7

Oxogluric acid (?-Ketoglutarate) is not approved for any indication in the world but is an investigational drug in the United States. In the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplem…

Kategori:
Acids, AcyclicDicarboxylic AcidsGlutarates +2
Target Protein:
Aspartate aminotransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxolamine Approved DB13216
small molecule | CAS: 959-14-8

Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant [L5416]. It is listed as a prescription drug in New Zealand legislation [L5419]. Oxolamine is also approved in Taiwan for the treatment of respiratory tr…

Kategori:
Antitussive AgentsCentral Nervous System AgentsCough and Cold Preparations +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxolinic acid DB13627
small molecule | CAS: 14698-29-4

Deskripsi belum tersedia.

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxomemazine DB13820
small molecule | CAS: 3689-50-7

Deskripsi belum tersedia.

Kategori:
Antihistamines for Systemic UseHeterocyclic Compounds, Fused-RingPhenothiazine Derivatives +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 19771-63-2

Procysteine has been used in trials studying the treatment of HIV Infections.

Kategori:
Amino AcidsAmino Acids, AcidicAmino Acids, Cyclic +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxprenolol Approved DB01580
small molecule | CAS: 6452-71-7

A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-Antagonists +32
Target Protein:
Beta-1 adrenergic receptorBeta-3 adrenergic receptorBeta-2 adrenergic receptor
Waktu Paruh1-2 hours
Vol. Distribusi-
Klirens-
Genetik -
Oxybenzone Approved DB01428
small molecule | CAS: 131-57-7

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultra…

Kategori:
Benzene DerivativesCompounds used in a research, industrial, or household settingCosmetics +6
Target Protein:
Hormone-sensitive lipaseProgesterone receptorAndrogen receptor +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxybuprocaine Approved DB00892
small molecule | CAS: 99-43-4

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ion…

Kategori:
Acids, CarbocyclicAminobenzoatesAnesthetics +15
Target Protein:
Sodium channel protein type 10 subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxybutynin Approved DB01062
small molecule | CAS: 5633-20-5

Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.…

Kategori:
Acids, CarbocyclicAgents producing tachycardiaAnticholinergic Agents +23
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M1
Waktu ParuhThe plasma eliminat…
Vol. DistribusiOxybutynin has a wi…
Klirens-
Genetik -
Oxycinchophen DB13596
small molecule | CAS: 485-89-2

Deskripsi belum tersedia.

Kategori:
Antiinflammatory and Antirheumatic ProductsMusculo-Skeletal SystemQuinolines +1
Target Protein:
Dihydroorotate dehydrogenase (quinone), mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxycodone Approved DB00497
small molecule | CAS: 76-42-6

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requi…

Kategori:
AlkaloidsAnalgesicsCentral Nervous System Agents +21
Target Protein:
Mu-type opioid receptorKappa-type opioid receptorDelta-type opioid receptor
Waktu ParuhThe apparent elimin…
Vol. Distribusi2.6L/kg.[Label]
KlirensTotal plasma cleara…
Genetik -
Oxygen Approved DB09140
small molecule | CAS: 7782-44-7

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exer…

Kategori:
ChalcogensElementsGases +3
Target Protein:
Cytochrome c oxidase subunit 1NADPH oxidase 1
Waktu ParuhApproximately 122.2…
Vol. Distribusi-
Klirens-
Genetik -
Oxymatrine DB16276
small molecule | CAS: 16837-52-8

Oxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects).

Kategori:
AlkaloidsAnti-Infective AgentsAntiarrhythmic agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxymetazoline Approved DB00935
small molecule | CAS: 1491-59-4

Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (?)-adrenergic agonist with affinity to both ?<sub>1</sub>- and ?<sub>2</sub>-adrenoceptors.[A215542] Oxymetazoline is available in various formulations with a wide variety of clinical…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-1 Receptor Agonists +25
Target Protein:
Alpha-1A adrenergic receptorAlpha-2A adrenergic receptorAlpha-2B adrenergic receptor +7
Waktu ParuhFollowing ocular ad…
Vol. DistribusiThere is limited in…
KlirensThere is limited in…
Genetik -
Oxymetholone Approved DB06412
small molecule | CAS: 434-07-1

Oxymetholone is a synthetic anabolic steroid marketed under the brand name Anapolon by Hoffmann La Roche Limitedand used in the treatment of osteoporosis, anaemia, and as an agent to stimulate muscle growth in malnourished or underdeveloped patients. Anabolic…

Kategori:
Alimentary Tract and MetabolismAnabolic AgentsAnabolic Agents for Systemic Use +20
Target Protein:
Androgen receptorNatriuretic peptides B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxymorphone Approved DB01192
small molecule | CAS: 76-41-5

An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia …

Kategori:
AdjuvantsAdjuvants, AnesthesiaAlkaloids +22
Target Protein:
Mu-type opioid receptorDelta-type opioid receptor
Waktu Paruh1.3 (+/-0.7) hours
Vol. Distribusi-
Klirens-
Genetik -
Oxyphenbutazone Approved DB03585
small molecule | CAS: 129-20-4

Oxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow suppression.

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAnalgesics +20
Target Protein:
AlbuminGroup IIE secretory phospholipase A2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxyphencyclimine Approved DB00383
small molecule | CAS: 125-53-1

Oxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAnticholinergic Agents +3
Target Protein:
Muscarinic acetylcholine receptor M5Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M1 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxyphenisatin DB04823
small molecule | CAS: 125-13-3

A laxative that undergoes enterohepatic circulation. It may cause jaundice.

Kategori:
Alimentary Tract and MetabolismContact LaxativesDrugs for Constipation +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxyphenisatin acetate Approved DB14627
small molecule | CAS: 115-33-3

Oxyphenisatin acetate is the pro-drug of [oxyphenisatin] (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942]

Kategori:
Gastrointestinal AgentsHeterocyclic Compounds, Fused-RingIndoles +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxyphenonium Approved DB00219
small molecule | CAS: 14214-84-7

A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drop…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAmines +12
Target Protein:
Muscarinic acetylcholine receptor M1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxypurinol DB05262
small molecule | CAS: 2465-59-0

Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.

Kategori:
Enzyme InhibitorsPyrazolesPyrimidines +1
Target Protein:
Xanthine dehydrogenase/oxidase
Waktu Paruh23.3 +/- 6.0 hours
Vol. Distribusi-
Klirens-
Genetik -
Oxyquinoline Approved DB11145
small molecule | CAS: 148-24-3

Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.

Kategori:
Alimentary Tract and MetabolismAnti-Infective Agents, LocalAntiinfectives and Antiseptics for Local Oral Treatment +11
Target Protein:
Methionine aminopeptidase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxytetracycline Approved DB00595
small molecule | CAS: 79-57-2

A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.

Kategori:
Agents that produce neuromuscular block (indirect)Alimentary Tract and MetabolismAnti-Bacterial Agents +16
Target Protein:
30S ribosomal protein S930S ribosomal protein S416S ribosomal RNA
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oxytocin Approved DB00107
biotech | CAS: 50-56-6

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A…

Kategori:
Amino Acids, Peptides, and ProteinsGenito Urinary System and Sex HormonesHormones +15
Target Protein:
Oxytocin receptorVasopressin V1b receptorVasopressin V2 receptor +1
Waktu ParuhThe plasma half-lif…
Vol. Distribusi-
KlirensIn a study that obs…
Genetik -
Ozagrel DB12017
small molecule | CAS: 82571-53-7

Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.

Kategori:
Acids, AcyclicAcrylatesCardiovascular Agents +6
Target Protein:
Mitogen-activated protein kinase 14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ozanezumab DB12891
biotech | CAS: 1310680-64-8

Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ozanimod Approved DB12612
small molecule | CAS: 1306760-87-1

Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) [L11025] and was approved by the FDA …

Kategori:
Antineoplastic and Immunomodulating AgentsBCRP/ABCG2 SubstratesCytochrome P-450 CYP2C8 Substrates +13
Target Protein:
Sphingosine 1-phosphate receptor 1Sphingosine 1-phosphate receptor 5
Waktu ParuhThe half-life of oz…
Vol. DistribusiThe average volume …
KlirensThe mean apparent o…
Genetik -
Ozarelix DB12581
small molecule | CAS: 295350-45-7

Ozarelix has been used in trials studying the treatment of Prostate Cancer, Benign Prostatic Hypertrophy, and Benign Prostatic Hyperplasia (BPH).

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ozekibart DB18675
biotech | CAS: 2539847-03-3

Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ozenoxacin Approved DB12924
small molecule | CAS: 245765-41-7

To date, ozenoxacin has been used in trials studying the treatment of impetigo. As of December 11, 2017 the FDA approved Ferrer Internacional S.A.'s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by *Staphy…

Kategori:
AminesAnti-Bacterial AgentsAnti-Infective Agents +9
Target Protein:
DNA gyrase subunit ADNA topoisomerase 4 subunit ADNA gyrase subunit B +1
Waktu Paruh-
Vol. DistribusiOzenoxacin undergoe…
KlirensOzenoxacin undergoe…
Genetik -
Ozone DB12510
small molecule | CAS: 10028-15-6

Ozone has been used in trials studying the treatment of Mild Asthma and Primary Apical Periodontite.

Kategori:
Compounds used in a research, industrial, or household settingGasesNoxae +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ozoralizumab DB12014
biotech | CAS: 1167985-17-2

Ozoralizumab has been used in trials studying the treatment of Rheumatoid Arthritis and Active Rheumatoid Arthritis.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 2460400-11-5

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Sulfur Compounds
Target Protein:
Prostaglandin G/H synthase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
P-113D DB04987
biotech | CAS: 190673-60-0

P-113D is a novel 12 amino-acid antimicrobial peptide drug derived from histatins, which are compounds found naturally in human saliva. It is being pursued as a potential treatment for cystic fibrosis by Demegen, Inc.

Kategori:
Amino Acids, Peptides, and ProteinsAntimicrobial Cationic PeptidesAntimicrobial Peptides +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
P-2045 Re-188 DB17204
biotech | CAS: 934712-65-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
P-42 peptide DB18610
biotech

P-42 peptide is a synthetic 23 amino acid peptide AASSGVSTPGSAGHDIITEQPRS derived from the Huntingtin protein

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
P-57AS3 DB06569
small molecule | CAS: 384329-61-7

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
p-Aminophenol DB14144
small molecule | CAS: 123-30-8

Deskripsi belum tersedia.

Kategori:
AminesAniline CompoundsBenzene Derivatives +4
Target Protein:
Carbonic anhydrase 14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Heat-labile enterotoxin B chain
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
P-Anisic Acid DB02795
small molecule | CAS: 100-09-4

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +5
Target Protein:
Phospholipase A2Group IIE secretory phospholipase A2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 104504-45-2

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +3
Target Protein:
Tyrosine-protein phosphatase non-receptor type 1Tyrosine--tRNA ligase, cytoplasmic
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 76410-58-7

p-Boronophenylalanine is under investigation in clinical trial NCT00039572 (Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain).

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 74-11-3

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates
Target Protein:
4-chlorobenzoyl CoA ligase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
p-Coumaric acid DB04066
small molecule | CAS: 501-98-4

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAdrenal Cortex HormonesAnti-Infective Agents +7
Target Protein:
Carbonic anhydrase 12Carbonic anhydrase 2Carbonic anhydrase 14 +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
p-Cumylphenol DB06902
small molecule | CAS: 599-64-4

Deskripsi belum tersedia.

Kategori:
Benzene Derivatives
Target Protein:
Estrogen-related receptor gamma
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 10301–10350 dari 14063
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